ES2386729T3 - Detección de metilación genica para el diagnostico de un trastorno proliferativo - Google Patents

Detección de metilación genica para el diagnostico de un trastorno proliferativo Download PDF

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Publication number: ES2386729T3
Authority: ES; Spain
Prior art keywords: seq; gstp1; dna; scorpion; reagents
Prior art date: 2005-09-15
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Active

Application number

ES06254777T

Other languages

English (en)

Spanish (es)

Inventor

Tatiana Vener

Jyoti Mehrotra

Shobha Varde

Abhijit Mazumder

Jon Baden

John Backus

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Janssen Diagnostics LLC

Original Assignee

Veridex LLC

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2005-09-15

Filing date

2006-09-14

Publication date

2012-08-28

2006-09-14 Application filed by Veridex LLC filed Critical Veridex LLC

2012-08-28 Application granted granted Critical

2012-08-28 Publication of ES2386729T3 publication Critical patent/ES2386729T3/es

Status Active legal-status Critical Current

2026-09-14 Anticipated expiration legal-status Critical

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Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6809—Methods for determination or identification of nucleic acids involving differential detection
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/154—Methylation markers
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/16—Primer sets for multiplex assays

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Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Zoology (AREA)
Engineering & Computer Science (AREA)
Analytical Chemistry (AREA)
Wood Science & Technology (AREA)
Genetics & Genomics (AREA)
Immunology (AREA)
Biotechnology (AREA)
Physics & Mathematics (AREA)
Microbiology (AREA)
Molecular Biology (AREA)
Biochemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
General Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Biophysics (AREA)
Pathology (AREA)
Hospice & Palliative Care (AREA)
Oncology (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

ES06254777T 2005-09-15 2006-09-14 Detección de metilación genica para el diagnostico de un trastorno proliferativo Active ES2386729T3 (es)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US71779005P	2005-09-15	2005-09-15
US717790P		2005-09-15

Publications (1)

Publication Number	Publication Date
ES2386729T3 true ES2386729T3 (es)	2012-08-28

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ID=37682657

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ES06254777T Active ES2386729T3 (es)	2005-09-15	2006-09-14	Detección de metilación genica para el diagnostico de un trastorno proliferativo

Country Status (12)

Country	Link
US (1)	US20070059753A1 (de)
EP (1)	EP1764419B1 (de)
JP (1)	JP2007075114A (de)
CN (1)	CN1966724A (de)
AR (1)	AR055437A1 (de)
AT (1)	ATE555214T1 (de)
AU (1)	AU2006213972A1 (de)
BR (1)	BRPI0604761A (de)
CA (1)	CA2561991A1 (de)
DK (1)	DK1764419T3 (de)
ES (1)	ES2386729T3 (de)
IL (1)	IL178118A0 (de)

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AUPP312998A0 (en) *	1998-04-23	1998-05-14	Commonwealth Scientific And Industrial Research Organisation	Diagnostic assay
US7906288B2 (en) *	2006-01-04	2011-03-15	The Johns Hopkins University	Compare-MS: method rapid, sensitive and accurate detection of DNA methylation
CN101153336B (zh)	2006-09-27	2011-09-07	香港中文大学	检测dna甲基化程度的方法和试剂盒
CA2699856C (en) *	2007-09-17	2019-08-20	Oncomethylome Sciences Sa	Improved methylation detection
JP2011509688A (ja) *	2008-01-22	2011-03-31	ベリデックス・エルエルシー	前立腺癌におけるｇｓｔｐ１高メチル化の発見
JP2011530287A (ja) *	2008-08-05	2011-12-22	ベリデックス・エルエルシー	前立腺癌メチル化分析
ES2686309T3 (es) *	2011-02-02	2018-10-17	Exact Sciences Development Company, Llc	Análisis digital de secuencia de la metilación de ADN
GB201322034D0 (en)	2013-12-12	2014-01-29	Almac Diagnostics Ltd	Prostate cancer classification
EP2942400A1 (de)	2014-05-09	2015-11-11	Lifecodexx AG	Multiplex-Nachweis von DNA, die aus einem spezifischen Zelltyp herrührt
US10801067B2 (en)	2014-05-09	2020-10-13	Eurofins Lifecodexx Gmbh	Detection of DNA that originates from a specific cell-type and related methods
EP3168309B8 (de)	2015-11-10	2020-06-03	Eurofins LifeCodexx GmbH	Nachweis von fötalen chromosomalen aneuploidien mittels dna-regionen mit unterschiedlicher methylierung zwischen dem fötus und der schwangeren frau
KR20250117473A (ko)	2017-11-30	2025-08-04	메이오 파운데이션 포 메디칼 에쥬케이션 앤드 리써치	유방암 검출방법
CN113215260A (zh) *	2021-06-18	2021-08-06	杭州昱鼎生物科技有限公司	一种gstp1，apc和rassf1在制备前列腺癌标志物中的应用及其试剂盒

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US4683195A (en)	1986-01-30	1987-07-28	Cetus Corporation	Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US5536648A (en) *	1988-12-09	1996-07-16	Amrad Corporation Limited	Amplified DNA assay using a double stranded DNA binding protein
GB9609441D0 (en)	1996-05-04	1996-07-10	Zeneca Ltd	Process
US6017704A (en) *	1996-06-03	2000-01-25	The Johns Hopkins University School Of Medicine	Method of detection of methylated nucleic acid using agents which modify unmethylated cytosine and distinguishing modified methylated and non-methylated nucleic acids
AUPP312998A0 (en) *	1998-04-23	1998-05-14	Commonwealth Scientific And Industrial Research Organisation	Diagnostic assay
GB9812768D0 (en)	1998-06-13	1998-08-12	Zeneca Ltd	Methods
US6686155B2 (en) *	2001-06-14	2004-02-03	Response Genetics, Inc.	Method of determining a chemotherapeutic regimen based on glutathione-S-transferase pi expression
AU2002352745A1 (en) *	2001-11-16	2003-06-10	The Johns Hopkins University School Of Medicine	Method of detection of prostate cancer
US20040146868A1 (en)	2003-01-24	2004-07-29	Epigenomics Ag	Methods and nucleic acids for the analysis of CpG dinucleotide methylation status associated with the development of peripheral zone prostate cancer
AU2003900368A0 (en) *	2003-01-24	2003-02-13	Human Genetic Signatures Pty Ltd	Assay for nucleic acid molecules
WO2004087957A2 (en) *	2003-04-03	2004-10-14	Oncomethylome Sciences S.A.	Hypermethylated genes and cervical cancer
EP1636381B1 (de) *	2003-06-23	2011-01-05	Epigenomics AG	Verfahren und nukleinsäuren zur analyse von störungen der proliferation von kolonzellen
EP1649050A2 (de) *	2003-06-24	2006-04-26	Epigenomics AG	Verbesserter heavymethyl-test zur methylierungsanalyse des gstpi-gens
US8062849B2 (en) *	2003-10-28	2011-11-22	The Johns Hopkins University	Quantitative multiplex methylation-specific PCR

2006
- 2006-09-13 US US11/520,233 patent/US20070059753A1/en not_active Abandoned
- 2006-09-14 ES ES06254777T patent/ES2386729T3/es active Active
- 2006-09-14 IL IL178118A patent/IL178118A0/en unknown
- 2006-09-14 JP JP2006249663A patent/JP2007075114A/ja active Pending
- 2006-09-14 AU AU2006213972A patent/AU2006213972A1/en not_active Abandoned
- 2006-09-14 AT AT06254777T patent/ATE555214T1/de active
- 2006-09-14 DK DK06254777.3T patent/DK1764419T3/da active
- 2006-09-14 EP EP06254777A patent/EP1764419B1/de not_active Not-in-force
- 2006-09-15 CA CA002561991A patent/CA2561991A1/en not_active Abandoned
- 2006-09-15 AR ARP060104052A patent/AR055437A1/es not_active Application Discontinuation
- 2006-09-15 CN CNA2006101431787A patent/CN1966724A/zh active Pending
- 2006-09-15 BR BRPI0604761-0A patent/BRPI0604761A/pt not_active IP Right Cessation

Also Published As

Publication number	Publication date
EP1764419A2 (de)	2007-03-21
AU2006213972A1 (en)	2007-03-29
CN1966724A (zh)	2007-05-23
EP1764419B1 (de)	2012-04-25
US20070059753A1 (en)	2007-03-15
JP2007075114A (ja)	2007-03-29
IL178118A0 (en)	2006-12-31
BRPI0604761A (pt)	2007-08-28
DK1764419T3 (da)	2012-08-06
ATE555214T1 (de)	2012-05-15
EP1764419A3 (de)	2007-06-13
AR055437A1 (es)	2007-08-22
CA2561991A1 (en)	2007-03-15

Publication	Publication Date	Title
US11965212B2 (en)	2024-04-23	Nucleic acid detection combining amplification with fragmentation
US20080254455A1 (en)	2008-10-16	Detecting prostate cancer
CN109952381B (zh)	2022-10-14	用于多重检测甲基化dna的方法
US9994900B2 (en)	2018-06-12	Composite biomarkers for non-invasive screening, diagnosis and prognosis of colorectal cancer
CA2610104A1 (en)	2008-04-30	Methylation of marker genes predicts aggressiveness of prostate cancer
ES2386729T3 (es)	2012-08-28	Detección de metilación genica para el diagnostico de un trastorno proliferativo
CA2712772A1 (en)	2009-07-30	Detection of gstp1 hypermethylation in prostate cancer
US8673563B2 (en)	2014-03-18	Amplification method of methylated or unmethylated nucleic acid
US11535897B2 (en)	2022-12-27	Composite epigenetic biomarkers for accurate screening, diagnosis and prognosis of colorectal cancer
US8377657B1 (en)	2013-02-19	Primers for analyzing methylated sequences and methods of use thereof
US20130309667A1 (en)	2013-11-21	Primers for analyzing methylated sequences and methods of use thereof
US20100003670A1 (en)	2010-01-07	Characterizing prostate cancer
EP1918711A2 (de)	2008-05-07	Verfahren und Kits zur Prostatakrebs-Feldeffektanalyse
US20080213781A1 (en)	2008-09-04	Methods of detecting methylation patterns within a CpG island
US20140315192A1 (en)	2014-10-23	Characterizing Prostate Cancer
US20130310550A1 (en)	2013-11-21	Primers for analyzing methylated sequences and methods of use thereof
MXPA06010628A (en)	2008-09-26	Detecting gene methylation
WO2018052883A1 (en)	2018-03-22	Method for detecting aberrant dna methylation of the tert promoter
HK40004890B (en)	2023-05-12	Multiple detection method of methylated dna