ES2397862T3 - Derivados de 1-aminociclohexano y de 1-ciclohexeno 4-heteroaril-sustituidos que tienen efecto sobre el sistema receptor opioide - Google Patents

Derivados de 1-aminociclohexano y de 1-ciclohexeno 4-heteroaril-sustituidos que tienen efecto sobre el sistema receptor opioide Download PDF

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ES2397862T3
ES2397862T3 ES07801431T ES07801431T ES2397862T3 ES 2397862 T3 ES2397862 T3 ES 2397862T3 ES 07801431 T ES07801431 T ES 07801431T ES 07801431 T ES07801431 T ES 07801431T ES 2397862 T3 ES2397862 T3 ES 2397862T3
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heteroaryl
substituted
aminocyclohexane
effect
polysubstituted
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Saskia Zemolka
Stefan Schunk
Werner Englberger
Babette-Yvonne Kögel
Klaus Linz
Hans Schick
Helmut Sonnenschein
Heinz Graubaum
Claudia Hinze
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Gruenenthal GmbH
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Abstract

Derivados heteroarilo sustituidos de fórmula general I donde A representa N o CR7-10, donde A es N dos veces como máximo; W representa O, S o NR4, con la condición de que, cuando W es O oS, A significa CR7-10; uno de los grupos B o C denota H, alquilo(C1-8), en cada caso saturado oinsaturado, lineal o ramificado, mono o polisustituido o no sustituido,COR12, SO2R12, arilo, cicloalquilo(C3-8) o heteroarilo unido mediante unalquilo(C1-3), en cada caso mono o polisustituido o no sustituido; arilo oheteroarilo, en cada caso mono o polisustituido o no sustituido; cicloalquilo(C3-8), en cada caso mono o polisustituido o no sustituido; y elotro grupo B o C representa **Fórmula**
ES07801431T 2006-07-18 2007-07-17 Derivados de 1-aminociclohexano y de 1-ciclohexeno 4-heteroaril-sustituidos que tienen efecto sobre el sistema receptor opioide Active ES2397862T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE102006033109 2006-07-18
DE102006033109A DE102006033109A1 (de) 2006-07-18 2006-07-18 Substituierte Heteroaryl-Derivate
PCT/EP2007/006325 WO2008009415A2 (de) 2006-07-18 2007-07-17 4-heteroaryl-substituierte 1-aminocyclohexan-1- und cyclohexen-1-derivate mit wirkung auf das opiod rezeptor system

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ES2397862T3 true ES2397862T3 (es) 2013-03-11

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