ES2507496T3 - Polipéptido para tratar o evitar adherencias - Google Patents

Polipéptido para tratar o evitar adherencias Download PDF

Info

Publication number
ES2507496T3
ES2507496T3 ES09830789.5T ES09830789T ES2507496T3 ES 2507496 T3 ES2507496 T3 ES 2507496T3 ES 09830789 T ES09830789 T ES 09830789T ES 2507496 T3 ES2507496 T3 ES 2507496T3
Authority
ES
Spain
Prior art keywords
adhesions
polypeptide
adhesion
composition
treating
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES09830789.5T
Other languages
English (en)
Spanish (es)
Inventor
Alyssa Panitch
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Moerae Matrix Inc
Original Assignee
Moerae Matrix Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Moerae Matrix Inc filed Critical Moerae Matrix Inc
Application granted granted Critical
Publication of ES2507496T3 publication Critical patent/ES2507496T3/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Dermatology (AREA)
  • Zoology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Surgery (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Materials For Medical Uses (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ES09830789.5T 2008-10-20 2009-10-20 Polipéptido para tratar o evitar adherencias Active ES2507496T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US106834P 1998-11-03
US10683408P 2008-10-20 2008-10-20
PCT/US2009/061345 WO2010065206A1 (en) 2008-10-20 2009-10-20 Polypeptide for treating or preventing adhesions

Publications (1)

Publication Number Publication Date
ES2507496T3 true ES2507496T3 (es) 2014-10-15

Family

ID=42108870

Family Applications (1)

Application Number Title Priority Date Filing Date
ES09830789.5T Active ES2507496T3 (es) 2008-10-20 2009-10-20 Polipéptido para tratar o evitar adherencias

Country Status (11)

Country Link
US (1) US9034815B2 (2)
EP (1) EP2349310B1 (2)
JP (1) JP5785085B2 (2)
KR (2) KR20170001756A (2)
CN (1) CN102256613B (2)
AU (1) AU2009322865B2 (2)
BR (1) BRPI0919759A2 (2)
CA (1) CA2741302C (2)
DK (1) DK2349310T3 (2)
ES (1) ES2507496T3 (2)
WO (1) WO2010065206A1 (2)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2007342674B2 (en) 2007-01-10 2013-09-19 Purdue Research Foundation Polypeptide inhibitors of HSP27 kinase and uses therefor
JP5703466B2 (ja) 2007-08-07 2015-04-22 パーデュー・リサーチ・ファウンデーションＰｕｒｄｕｅ Ｒｅｓｅａｒｃｈ Ｆｏｕｎｄａｔｉｏｎ キナーゼ阻害薬およびその使用
CA2744104C (en) 2008-12-10 2017-07-18 Purdue Research Foundation Cell-permeant peptide-based inhibitor of kinases
US9890195B2 (en) 2009-07-27 2018-02-13 Purdue Research Foundation MK2 inhibitor compositions and methods to enhance neurite outgrowth, neuroprotection, and nerve regeneration
US20130115256A1 (en) * 2010-05-24 2013-05-09 Cynthia Lander Methods for treating or preventing vascular graft failure
BR112013026313A8 (pt) * 2011-04-12 2018-01-30 Moerae Matrix Inc composições e métodos para prevenir ou tratar doenças, condições ou processos caracterizados por proliferação anormal de fibroblastos e depósito de matriz extracelular
US9890200B2 (en) 2011-04-12 2018-02-13 Moerae Matrix, Inc. Compositions and methods for preventing or treating diseases, conditions, or processes characterized by aberrant fibroblast proliferation and extracellular matrix deposition
WO2013134636A1 (en) 2012-03-09 2013-09-12 Purdue Research Foundation Compositions and methods for delivery of kinase inhibiting peptides
KR102266659B1 (ko) * 2012-03-23 2021-06-17 아미크로베, 인코포레이티드. 조직-적합성 특성을 갖는 항균물질의 조성물 및 용도
US20140072613A1 (en) * 2012-09-10 2014-03-13 Cynthia Lander Compositions and Methods for Treating Cutaneous Scarring
WO2016061145A1 (en) * 2014-10-13 2016-04-21 Symic Biomedical, Inc. Synthetic proteoglycans for preventing tissue adhesion
CN107106650A (zh) * 2014-11-17 2017-08-29 莫伊莱麦屈克斯公司 用于预防或治疗表征为异常的成纤维细胞增殖和细胞外基质沉积的疾病、状况或过程的组合物和方法
EP3242886A4 (en) 2015-01-08 2018-08-29 Moerae Matrix, Inc., Formulation of mk2 inhibitor peptides
JP2018512401A (ja) 2015-03-12 2018-05-17 モイライ マトリックス インコーポレイテッド Ｍｋ２阻害剤ペプチド含有組成物を用いた非小細胞肺癌の治療を目的とするその使用
CA3058901C (en) 2017-04-06 2025-05-06 Amicrobe, Inc. Compositions and uses of topically applied antimicrobial agents offering improvements in performance and safety
RU2741247C1 (ru) * 2020-10-13 2021-01-22 федеральное государственное бюджетное образовательное учреждение высшего образования "Ростовский государственный медицинский университет" Министерства здравоохранения Российской Федерации (ФГБОУ ВО РостГМУ Минздрава России) Способ профилактики перитонеальных спаек женского таза

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1521000A (en) 1975-06-13 1978-08-09 Syntex Puerto Rico Inc Inhalation device
US4227522A (en) 1978-09-05 1980-10-14 Syntex Puerto Rico, Inc. Inhalation device
US4192309A (en) 1978-09-05 1980-03-11 Syntex Puerto Rico, Inc. Inhalation device with capsule opener
US4778054A (en) 1982-10-08 1988-10-18 Glaxo Group Limited Pack for administering medicaments to patients
GB2129691B (en) 1982-10-08 1987-08-05 Glaxo Group Ltd Devices for administering medicaments to patients
AU591152B2 (en) 1985-07-30 1989-11-30 Glaxo Group Limited Devices for administering medicaments to patients
JPH05963A (ja) 1990-04-13 1993-01-08 Toray Ind Inc ポリペプチド類組成物
AU4115693A (en) 1992-04-24 1993-11-29 Sri International In vivo homologous sequence targeting in eukaryotic cells
US6582728B1 (en) 1992-07-08 2003-06-24 Inhale Therapeutic Systems, Inc. Spray drying of macromolecules to produce inhaleable dry powders
DE733059T1 (de) 1993-12-09 1997-08-28 Univ Jefferson Verbindungen und verfahren zur ortsspezifischen mutation in eukaryotischen zellen
US20030190364A1 (en) 2002-04-01 2003-10-09 Alyssa Panitch Biological affinity based delivery systems
US8008093B2 (en) * 2004-12-02 2011-08-30 The University Of North Carolina At Chapel Hill Inhibition of Hsp27 phosphorylation for the treatment of blistering disorders
US7767642B2 (en) * 2005-04-15 2010-08-03 Arizona Biomedical Research Commission Therapeutic peptides for the treatment of metastatic cancer
AU2007342674B2 (en) * 2007-01-10 2013-09-19 Purdue Research Foundation Polypeptide inhibitors of HSP27 kinase and uses therefor
US20080293640A1 (en) * 2007-01-10 2008-11-27 Arizona Board of Regents, A body Corporate, of the State of Arizona, acting for and on behalf of Polypeptide inhibitors of HSP27 kinase and uses therefor
WO2008109794A2 (en) * 2007-03-08 2008-09-12 Tufts Medical Center The role of the mk2 pathway in treating fibrosis and scarring
JP5703466B2 (ja) * 2007-08-07 2015-04-22 パーデュー・リサーチ・ファウンデーションＰｕｒｄｕｅ Ｒｅｓｅａｒｃｈ Ｆｏｕｎｄａｔｉｏｎ キナーゼ阻害薬およびその使用
WO2009123759A2 (en) * 2008-04-02 2009-10-08 Moerae Matrix, Inc. Therapeutic uses of biocompatible biogel compositions

Also Published As

Publication number Publication date
DK2349310T3 (da) 2014-08-11
BRPI0919759A2 (pt) 2017-03-21
US9034815B2 (en) 2015-05-19
JP5785085B2 (ja) 2015-09-24
WO2010065206A1 (en) 2010-06-10
US20130101671A9 (en) 2013-04-25
EP2349310A4 (en) 2012-11-21
EP2349310B1 (en) 2014-07-23
CN102256613A (zh) 2011-11-23
KR20170001756A (ko) 2017-01-04
JP2012506442A (ja) 2012-03-15
AU2009322865B2 (en) 2013-07-18
KR20110095867A (ko) 2011-08-25
CA2741302C (en) 2017-02-28
EP2349310A1 (en) 2011-08-03
US20100098760A1 (en) 2010-04-22
AU2009322865A1 (en) 2010-06-10
KR101884616B1 (ko) 2018-08-06
CN102256613B (zh) 2014-09-10
CA2741302A1 (en) 2010-06-10

Similar Documents

Publication Publication Date Title
ES2507496T3 (es) Polipéptido para tratar o evitar adherencias
ES2145744T5 (es) Procedimientos para tratar las enfermedades inducidas por el factor de necrosis tumoral.
ES2312179T3 (es) Terapia combinada que utiliza un inhibidor del il-1 para el tratamiento de enfermedades mediadas por el il-1.
ES2286247T3 (es) Proteinas anexinicas modificacdas y tratamiento de la trombosis.
JPH07509223A (ja) インターロイキン−１媒介疾患および腫瘍壊死因子媒介疾患の治療方法
ES2794082T3 (es) Uso de dímeros de IL-22 en la fabricación de medicamentos para tratar la pancreatitis
ES2373039T3 (es) Composiciones y métodos para el tratamiento de lesiones del cns.
US7645733B2 (en) Tissue protective cytokines for the treatment and prevention of sepsis and the formation of adhesions
ES2218666T3 (es) Producto a base del factor de crecimiento de queratinocitos-2 (kggf-2).
ES2297286T3 (es) Uso de productos proteicos del factor de crecimiento de queratinocitos-2.
HK1161105A (en) Polypeptide for treating or preventing adhesions
HK1161105B (en) Polypeptide for treating or preventing adhesions
ES2351005B1 (es) Uso de anhidrasa carbónica ii para la elaboración de un medicamento.
JP2000509073A (ja) 虚血再灌流傷害の治療または予防の方法
JP2023511245A (ja) Ｖｅ－ｐｔｐホスファターゼの阻害は腎臓を虚血再灌流障害から保護する
WO2012030949A2 (en) B2-glycoprotein i peptide inhibitors
JP3569904B2 (ja) 臓器障害治療薬
EP1948216B1 (en) Treatment of acute renal failure with soluble thrombomodulin
WO2010006635A1 (en) Treatment of inflammatory bowel disease
CN106061495B (zh) 肺内炎症的减弱
CA2738757A1 (en) Pharmaceutical compositions and methods of use for the prevention and treatment of hypoxic injury
CN118369351A (zh) Dsg2组合物和方法
MXPA98008946A (en) Method of treatment or prevention of the injury caused by isquemia-reperfus