ES2527102T3 - Composiciones y métodos para el tratamiento de trastornos relacionados con la coagulación - Google Patents

Composiciones y métodos para el tratamiento de trastornos relacionados con la coagulación Download PDF

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ES2527102T3
ES2527102T3 ES04754498.6T ES04754498T ES2527102T3 ES 2527102 T3 ES2527102 T3 ES 2527102T3 ES 04754498 T ES04754498 T ES 04754498T ES 2527102 T3 ES2527102 T3 ES 2527102T3
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treatment
coagulation
compositions
methods
disorders related
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ES04754498.6T
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Jin-An Jiao
Hing C. Wong
Jack O. Egan
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Genentech Inc
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Genentech Inc
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/36—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against blood coagulation factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/40—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum bacterial
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/55—Fab or Fab'

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Immunology (AREA)
  • Hematology (AREA)
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  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
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  • Epidemiology (AREA)
  • Microbiology (AREA)
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  • Oncology (AREA)
  • Rheumatology (AREA)
  • Communicable Diseases (AREA)
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  • Biomedical Technology (AREA)
  • Pulmonology (AREA)
  • Neurosurgery (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Dermatology (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)

Abstract

Utilización de al menos un anticuerpo o fragmento del mismo, que se une específicamente al factor tisular (TF) para la fabricación de un medicamento para la prevención o tratamiento de la lesión pulmonar aguda (ALI) o el síndrome de dificultad respiratoria aguda (ARDS) en un mamífero, en la que el anticuerpo tiene las CDR de cadena ligera 1 a 3 y las CDR de cadena pesada 1 a 3 tal como se muestra por LASQTIDTWLA; AATNLAD; QQVYSSPFT; DYNVY; YIDPYNGITIYDQNFKG; y DVTTALDF, respectivamente.

Description

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Claims (1)

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ES04754498.6T 2003-06-19 2004-06-04 Composiciones y métodos para el tratamiento de trastornos relacionados con la coagulación Expired - Lifetime ES2527102T3 (es)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US48025403P 2003-06-19 2003-06-19
US480254P 2003-06-19
US53889204P 2004-01-22 2004-01-22
US538892P 2004-01-22
PCT/US2004/017900 WO2005004793A2 (en) 2003-06-19 2004-06-04 Compositions and methods for treating coagulation related disorders

Publications (1)

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ES2527102T3 true ES2527102T3 (es) 2015-01-20

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ES04754498.6T Expired - Lifetime ES2527102T3 (es) 2003-06-19 2004-06-04 Composiciones y métodos para el tratamiento de trastornos relacionados con la coagulación

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US (5) US20060159675A1 (es)
EP (1) EP1644039B1 (es)
JP (2) JP5114055B2 (es)
KR (1) KR100912381B1 (es)
CN (1) CN1863556B (es)
AU (1) AU2004255553B2 (es)
CA (1) CA2530980A1 (es)
ES (1) ES2527102T3 (es)
MX (1) MXPA05013789A (es)
TW (1) TWI339585B (es)
WO (1) WO2005004793A2 (es)

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JP5114055B2 (ja) 2013-01-09
CN1863556B (zh) 2012-05-16
US20150010558A1 (en) 2015-01-08
US20110182900A1 (en) 2011-07-28
WO2005004793A2 (en) 2005-01-20
JP2010285452A (ja) 2010-12-24
EP1644039A4 (en) 2007-07-11
JP2006528130A (ja) 2006-12-14
EP1644039B1 (en) 2014-10-01
TWI339585B (en) 2011-04-01
KR100912381B1 (ko) 2009-08-19
EP1644039A2 (en) 2006-04-12
CA2530980A1 (en) 2005-01-20
TW200505481A (en) 2005-02-16
US20060159675A1 (en) 2006-07-20
HK1098383A1 (en) 2007-07-20
US20090136501A1 (en) 2009-05-28
US20130011389A1 (en) 2013-01-10
AU2004255553A1 (en) 2005-01-20
WO2005004793A3 (en) 2005-07-28
MXPA05013789A (es) 2006-06-27
WO2005004793A9 (en) 2006-11-02
KR20060031634A (ko) 2006-04-12
CN1863556A (zh) 2006-11-15
AU2004255553A2 (en) 2005-01-20
AU2004255553B2 (en) 2009-08-20

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