ES2528482T3 - Producción de ácidos grasos y derivados de los mismos - Google Patents

Producción de ácidos grasos y derivados de los mismos Download PDF

Info

Publication number
ES2528482T3
ES2528482T3 ES07809099.0T ES07809099T ES2528482T3 ES 2528482 T3 ES2528482 T3 ES 2528482T3 ES 07809099 T ES07809099 T ES 07809099T ES 2528482 T3 ES2528482 T3 ES 2528482T3
Authority
ES
Spain
Prior art keywords
derivatives
production
fatty acids
nucleic acid
polypeptide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES07809099.0T
Other languages
English (en)
Inventor
Jay D. Keasling
Zhihao Hu
Chris Somerville
George Church
David Berry
Lisa Friedman
Andreas Schirmer
Shane Brubaker
Stephen B. DEL CARDAYRÉ
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
LS9 Inc
Original Assignee
LS9 Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38650090&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2528482(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from PCT/US2007/003736 external-priority patent/WO2008100251A1/en
Application filed by LS9 Inc filed Critical LS9 Inc
Application granted granted Critical
Publication of ES2528482T3 publication Critical patent/ES2528482T3/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52Genes encoding for enzymes or proenzymes
    • CCHEMISTRY; METALLURGY
    • C10PETROLEUM, GAS OR COKE INDUSTRIES; TECHNICAL GASES CONTAINING CARBON MONOXIDE; FUELS; LUBRICANTS; PEAT
    • C10LFUELS NOT OTHERWISE PROVIDED FOR; NATURAL GAS; SYNTHETIC NATURAL GAS OBTAINED BY PROCESSES NOT COVERED BY SUBCLASSES C10G OR C10K; LIQUIFIED PETROLEUM GAS; USE OF ADDITIVES TO FUELS OR FIRES; FIRE-LIGHTERS
    • C10L1/00Liquid carbonaceous fuels
    • C10L1/02Liquid carbonaceous fuels essentially based on components consisting of carbon, hydrogen, and oxygen only
    • CCHEMISTRY; METALLURGY
    • C10PETROLEUM, GAS OR COKE INDUSTRIES; TECHNICAL GASES CONTAINING CARBON MONOXIDE; FUELS; LUBRICANTS; PEAT
    • C10LFUELS NOT OTHERWISE PROVIDED FOR; NATURAL GAS; SYNTHETIC NATURAL GAS OBTAINED BY PROCESSES NOT COVERED BY SUBCLASSES C10G OR C10K; LIQUIFIED PETROLEUM GAS; USE OF ADDITIVES TO FUELS OR FIRES; FIRE-LIGHTERS
    • C10L1/00Liquid carbonaceous fuels
    • C10L1/02Liquid carbonaceous fuels essentially based on components consisting of carbon, hydrogen, and oxygen only
    • C10L1/026Liquid carbonaceous fuels essentially based on components consisting of carbon, hydrogen, and oxygen only for compression ignition
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/64Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02EREDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E50/00Technologies for the production of fuel of non-fossil origin
    • Y02E50/10Biofuels, e.g. bio-diesel

Landscapes

  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medicinal Chemistry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Fats And Perfumes (AREA)
  • Liquid Carbonaceous Fuels (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Microorganismo que comprende una o mas secuencias de acido nucleico ex6geno que codifican para un polipeptido que comprende una ester de cera sintasa de EC 2.3.1.75, y una secuencia de acido nucleico que codifica para un polipeptido que comprende una acetil-CoA carboxilasa de EC 6.4.1.2, en el que dichas secuencias de acido nucleico se sobreexpresan.

Description

imagen1
imagen2
imagen3
imagen4
imagen5
imagen6
imagen7
imagen8
imagen9
imagen10
imagen11
imagen12
imagen13
imagen14
imagen15
imagen16
imagen17
imagen18
imagen19
imagen20
imagen21
imagen22
imagen23
imagen24
imagen25
imagen26
imagen27
imagen28
imagen29
imagen30

Claims (1)

  1. imagen1
    imagen2
ES07809099.0T 2006-05-19 2007-05-18 Producción de ácidos grasos y derivados de los mismos Active ES2528482T3 (es)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US80199506P 2006-05-19 2006-05-19
US80201606P 2006-05-19 2006-05-19
US801995P 2006-05-19
US802016P 2006-05-19
PCT/US2007/003736 WO2008100251A1 (en) 2007-02-13 2007-02-13 Modified microorganism uses therefor
WOPCT/US2007/003736 2007-02-13
US90854707P 2007-03-28 2007-03-28
US908547P 2007-03-28
PCT/US2007/011923 WO2007136762A2 (en) 2006-05-19 2007-05-18 Production of fatty acids and derivatives thereof

Publications (1)

Publication Number Publication Date
ES2528482T3 true ES2528482T3 (es) 2015-02-10

Family

ID=38650090

Family Applications (3)

Application Number Title Priority Date Filing Date
ES07809099.0T Active ES2528482T3 (es) 2006-05-19 2007-05-18 Producción de ácidos grasos y derivados de los mismos
ES14193614T Active ES2763624T3 (es) 2006-05-19 2007-05-18 Producción de ácidos grasos y derivados de los mismos
ES11005423.6T Active ES2529176T3 (es) 2006-05-19 2007-05-18 Producción de ácidos grasos y derivados de los mismos

Family Applications After (2)

Application Number Title Priority Date Filing Date
ES14193614T Active ES2763624T3 (es) 2006-05-19 2007-05-18 Producción de ácidos grasos y derivados de los mismos
ES11005423.6T Active ES2529176T3 (es) 2006-05-19 2007-05-18 Producción de ácidos grasos y derivados de los mismos

Country Status (10)

Country Link
EP (3) EP2194119A3 (es)
JP (3) JP5933909B2 (es)
KR (1) KR20090029708A (es)
AU (1) AU2007254151A1 (es)
BR (1) BRPI0712205A2 (es)
CA (1) CA2650773C (es)
DK (1) DK2840131T3 (es)
ES (3) ES2528482T3 (es)
MX (3) MX356086B (es)
WO (1) WO2007136762A2 (es)

Families Citing this family (153)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8110670B2 (en) 2006-05-19 2012-02-07 Ls9, Inc. Enhanced production of fatty acid derivatives
ES2528482T3 (es) * 2006-05-19 2015-02-10 Ls9, Inc. Producción de ácidos grasos y derivados de los mismos
US20100242345A1 (en) 2006-05-19 2010-09-30 LS9, Inc Production of fatty acids & derivatives thereof
KR101862691B1 (ko) 2007-05-22 2018-05-31 알이지 라이프 사이언시스, 엘엘씨 탄화수소-생산 유전자와 이들의 이용 방법
WO2009009391A2 (en) * 2007-07-06 2009-01-15 Ls9, Inc. Systems and methods for the production of fatty esters
US7897369B2 (en) 2007-08-27 2011-03-01 Regents Of The University Of Minnesota Isoprenoid wax ester synthases, isoprenoid acyl CoA-synthetases, and uses thereof
US8313934B2 (en) 2007-09-27 2012-11-20 Ls9, Inc. Reduction of the toxic effect of impurities from raw materials by extractive fermentation
CL2008002961A1 (es) 2007-10-04 2009-05-08 Bio Arch Lab Inc Metodo para convertir un monosacarido u oligosacarido apropiado en un quimico generico que comprende contactar dichos moleculas con un sistema microbiano que comprende uno o mas genes que codifican y expresan una via de biosintesis.
MX2010006539A (es) 2007-12-11 2011-02-23 Synthetic Genomics Inc Secrecion de acidos grasos por parte de microorganismos fotosinteticos.
US8183028B2 (en) 2007-12-21 2012-05-22 Ls9, Inc. Methods and compositions for producing olefins
EP2075337A1 (en) * 2007-12-27 2009-07-01 Wageningen Universiteit Method for the enzymatic production of fatty alcohol and/or fatty acid
EP2285948B1 (en) 2008-03-03 2014-01-08 Joule Unlimited Technologies, Inc. Engineered co2 fixing microorganisms producing carbon-based products of interest
US8048654B2 (en) 2010-06-09 2011-11-01 Joule Unlimited Technologies, Inc. Methods and compositions for the recombinant biosynthesis of fatty acids and esters
EP3450550A1 (en) 2008-03-05 2019-03-06 Genomatica, Inc. Primary alcohol producing organisms
JP5366113B2 (ja) * 2008-03-25 2013-12-11 独立行政法人農業・食品産業技術総合研究機構 脂肪酸エステル生産性酵母
GB0807619D0 (en) 2008-04-28 2008-06-04 Whitton Peter A Production of bio fuels from plant tissue culture sources
CA3101888A1 (en) * 2008-05-16 2009-11-19 REG Life Sciences, LLC Methods and compositions for producing hydrocarbons
WO2010011754A2 (en) * 2008-07-22 2010-01-28 Board Of Regents, The University Of Texas System Continuous production and excretion of waxy products from photosynthetic organisms
US8097439B2 (en) 2008-10-07 2012-01-17 Ls9, Inc. Methods and compositions for producing fatty aldehydes
CN103725717A (zh) 2008-10-17 2014-04-16 焦耳无限科技公司 微生物的乙醇生产
WO2010048568A1 (en) * 2008-10-23 2010-04-29 Targeted Growth, Inc. Modified photosynthetic microorganisms for producing triglycerides
CN105154380B (zh) 2008-10-28 2018-11-09 Reg生命科学有限责任公司 用于产生脂肪醇的方法和组合物
CA2747516C (en) 2008-12-23 2019-11-05 Ls9, Inc. Methods and compositions related to thioesterase enzymes
US8835137B2 (en) 2008-12-23 2014-09-16 Matrix Genetics, Llc Modified photosynthetic microorganisms with reduced glycogen and their use in producing carbon-based products
CA2758301A1 (en) * 2009-04-10 2010-10-14 Ls9, Inc. Production of fatty acid derivatives
EP2425007A4 (en) * 2009-04-27 2013-01-02 Ls9 Inc PREPARATION OF FATTY ACID ESTERS
WO2010127318A2 (en) * 2009-05-01 2010-11-04 The Regents Of The University Of California Product of fatty acid esters from biomass polymers
BRPI1014338B1 (pt) 2009-06-25 2019-12-24 Shell Int Research método para injetar água em uma formação contendo hidrocarbonetos, e, método para preparar uma água com salinidade elevada
WO2011008565A1 (en) 2009-06-29 2011-01-20 Synthetic Genomics, Inc. Acyl-acp thioesterase genes and uses therefor
EP2449124B1 (en) 2009-06-30 2015-05-27 Codexis, Inc. Production of fatty alcohols with fatty alcohol forming acyl-coa reductases (far)
US7955820B1 (en) 2009-07-09 2011-06-07 Joule Unlimited, Inc. Methods and compositions for the recombinant biosynthesis of n-alkanes
US7794969B1 (en) 2009-07-09 2010-09-14 Joule Unlimited, Inc. Methods and compositions for the recombinant biosynthesis of n-alkanes
WO2011011568A2 (en) * 2009-07-24 2011-01-27 The Regenst Of The University Of California Methods and compositions for the production of fatty acids in photosynthetic prokaryotic microorganisms
WO2011019858A1 (en) 2009-08-11 2011-02-17 Synthetic Genomics, Inc. Microbial production of fatty alcohols
EP2719757A1 (en) * 2009-09-04 2014-04-16 President and Fellows of Harvard College Production of secreted bioproducts from photosynthetic microbes
MX2012003472A (es) 2009-09-25 2012-05-22 Ls9 Inc Produccion de derivados de acido graso.
CA2775390C (en) 2009-09-27 2021-06-29 Opx Biotechnologies, Inc. Method for producing 3-hydroxypropionic acid and other products
US20110124063A1 (en) * 2009-11-20 2011-05-26 Opx Biotechnologies, Inc. Methods, Systems, and Compositions for Microbial Bio-Production of Biomolecules Using Syngas Components, or Sugars, as Feedstocks
US20110151526A1 (en) 2009-12-22 2011-06-23 Charles Winston Saunders Branched-Chain Fatty Acids And Biological Production Thereof
US8617856B2 (en) 2010-01-07 2013-12-31 Wisconsin Alumni Research Foundation Fatty acid-producing hosts
US8933131B2 (en) 2010-01-12 2015-01-13 The Procter & Gamble Company Intermediates and surfactants useful in household cleaning and personal care compositions, and methods of making the same
US8530221B2 (en) 2010-01-14 2013-09-10 Ls9, Inc. Production of branched chain fatty acids and derivatives thereof in recombinant microbial cells
CN102311966B (zh) * 2010-06-30 2016-04-13 中国科学院青岛生物能源与过程研究所 用于合成脂肪醇的构建体,载体,蓝细菌,以及在蓝细菌中生产脂肪醇的方法
EP2524035A2 (en) 2010-01-15 2012-11-21 Shell Internationale Research Maatschappij B.V. Constructs, vectors and cyanobacteria for the synthesis of fatty alcohols, and methods for producing fatty alcohols in cyanobacteria
WO2011100667A1 (en) * 2010-02-14 2011-08-18 Ls9, Inc. Surfactant and cleaning compositions comprising microbially produced branched fatty alcohols
WO2011127069A1 (en) * 2010-04-06 2011-10-13 Targeted Growth, Inc. Modified photosynthetic microorganisms for producing lipids
WO2011155799A2 (ko) * 2010-06-10 2011-12-15 한국과학기술원 탄화수소 생성능을 가지는 변이 미생물 및 이를 이용한 탄화수소의 제조방법
US8999683B2 (en) 2010-06-18 2015-04-07 Technical University Of Denmark Production of biodiesel by yeast from lignocellulose and glycerol
EP2582798A1 (en) * 2010-06-18 2013-04-24 Technical University of Denmark Production of biodiesel by yeast from lignocellulose and glycerol
FI122886B (fi) 2010-06-24 2012-08-31 Valtion Teknillinen Geneettisesti muokattuja sieniä ja niiden käyttö lipidituotannossa
EP2585587B1 (en) * 2010-06-28 2017-08-09 Codexis, Inc. Fatty alcohol forming acyl reductases (fars) and methods of use thereof
EP2407531A1 (en) 2010-07-16 2012-01-18 Neste Oil Oyj Microorganisms with extended substrate utilization range
WO2012017083A1 (en) 2010-08-06 2012-02-09 Jens Nielsen Methods and products for production of wax esters
WO2012037288A2 (en) * 2010-09-14 2012-03-22 Joule Unlimited Technologies, Inc. Methods and compositions for the extracellular transport of biosynthetic hydrocarbons and other molecules
US8372610B2 (en) 2010-09-15 2013-02-12 Ls9, Inc. Production of odd chain fatty acid derivatives in recombinant microbial cells
WO2012047832A2 (en) 2010-10-07 2012-04-12 Shell Oil Company Process for the production of alcohols from biomass
WO2012061596A1 (en) 2010-11-05 2012-05-10 Shell Oil Company Treating biomass to produce materials useful for biofuels
WO2012071439A1 (en) * 2010-11-22 2012-05-31 The Regents Of The University Of California Host cells and methods for producing diacid compounds
PL2465868T3 (pl) 2010-12-17 2016-08-31 Neste Oyj Ulepszenie produkcji lipidów
US8609379B2 (en) 2010-12-20 2013-12-17 Shell Oil Company Process for the production of alcohols from biomass
AU2011349729B2 (en) 2010-12-23 2015-09-24 Exxonmobil Research And Engineering Company Genetically engineered microorganisms comprising 4-hydroxybenzoly-CoA thioesterases and methods of using the same for producing free fatty acids and fatty acid derivatives
EP2655615A4 (en) 2010-12-23 2014-04-23 Exxonmobil Res & Eng Co PROKARYOTIC ACYL ACP THIOESTERASES FOR THE PREPARATION OF FATTY ACIDS IN GENETICALLY MODIFIED MICROORGANISMS
PL2655612T3 (pl) 2010-12-23 2017-12-29 Shell Internationale Research Maatschappij B.V. Czynniki uszkadzające geny produkujące pochodne tłuszczowego acylo-coa
US9187726B2 (en) 2010-12-23 2015-11-17 Exxonmobil Research And Engineering Company Culturing a microorganism in a medium with an elevated level of a carboxylate counterion source
CA2823928C (en) 2011-01-14 2020-09-22 Ls9, Inc. Production of branched chain fatty acids and derivatives thereof in recombinant microbial cells
US9096859B2 (en) 2011-01-26 2015-08-04 The Regents Of The University Of California Microbial conversion of plant biomass to advanced biofuels
WO2012138423A1 (en) 2011-02-17 2012-10-11 The Procter & Gamble Company Compositions comprising mixtures of c10-c13 alkylphenyl sulfonates
MX2013009546A (es) 2011-02-17 2013-11-22 Procter & Gamble Alquilfenil sulfonatos lineales de base biologica.
US9029124B2 (en) 2011-03-23 2015-05-12 Joule Unlimited Technologies, Inc. Photoalkanogens with increased productivity
US20140215904A1 (en) 2011-03-30 2014-08-07 Ls9, Inc. Compositions comprising and methods for producing beta-hydroxy fatty acid esters
EP2691517A4 (en) 2011-03-30 2015-04-22 Codexis Inc FERMENTATION OF PENTOSES BY A RECOMBINANT MICROORGANISM
BR112013033672A2 (pt) * 2011-06-30 2017-03-14 Invista Tech Sarl método para converter um composto, cultura substancialmente pura de células hospedeiras e cèlula isolada
BR112013033614A2 (pt) 2011-06-30 2018-05-29 Codexis Inc fermentação de pentose por microorganismo recombinante
MX2013015327A (es) 2011-06-30 2014-01-31 Exxonmobil Res & Eng Co Regulacion de genes toxina y antitoxina para contencion biologica.
US20130059295A1 (en) * 2011-07-14 2013-03-07 The Regents Of The University Of California Host Cells and Methods for Producing Fatty Acid
BR112014002624A8 (pt) * 2011-08-03 2017-07-04 Ls9 Inc Microorganismo recombinante e cultura de microorganismo recombinante
US9650652B2 (en) 2011-08-09 2017-05-16 Cornell University Production of carboxylates and methane from biomass waste
DE102011110946A1 (de) 2011-08-15 2016-01-21 Evonik Degussa Gmbh Biotechnologisches Syntheseverfahren von omegafunktionalisierten Carbonsäuren und Carbonsäure-Estern aus einfachen Kohlenstoffquellen
DE102011110945A1 (de) 2011-08-15 2013-02-21 Evonik Degussa Gmbh Biotechnologisches Syntheseverfahren von organischen Verbindungen mit alkIL-Genprodukt
ES2396823B1 (es) * 2011-08-18 2014-01-28 Iden Biotechnology S.L. Producción de biodiesel a partir de glicerina.
CN102952818B (zh) * 2011-08-26 2016-03-02 中国科学院青岛生物能源与过程研究所 用于在蓝细菌中提高脂肪醇产量的构建体和方法
CN103975070A (zh) 2011-09-27 2014-08-06 艾克森美孚研究与工程公司 酰基-酰基载体蛋白(acyl-acp)蜡酯合酶
WO2013096475A1 (en) * 2011-12-19 2013-06-27 Joule Unlimited Technologies, Inc. Extracellular transport of biosynthetic hydrocarbons and other molecules
US20140357727A1 (en) * 2011-12-20 2014-12-04 Codexis, Inc. Fatty alcohol forming acyl reductase (far) variants and methods of use
EP2820029A4 (en) * 2012-02-29 2015-12-23 Exxonmobil Res & Eng Co FOUR GENE SIGNAL PATH FOR WAXESES SYNTHESIS
US8962299B2 (en) 2012-02-29 2015-02-24 Exxonmobil Research And Engineering Company Four-gene pathway for wax ester synthesis
WO2013152052A2 (en) 2012-04-02 2013-10-10 Ls9, Inc. Novel car enzymes and improved production of fatty alcohols
CA2883968C (en) 2012-04-02 2022-08-23 REG Life Sciences, LLC Improved production of fatty acid derivatives
KR102278343B1 (ko) 2012-04-13 2021-07-16 게노마티카 인코포레이티드 알카놀아미드들 및 아미도아민들의 미생물에 의한 생산 및 이의 용도
US20150133698A1 (en) 2012-04-20 2015-05-14 Codexis, Inc. Production of fatty alcohols from engineered microorganisms
WO2013166075A1 (en) 2012-04-30 2013-11-07 Woods Hole Oceanographic Institution Cobalamin acquisition protein and use thereof
BR112014027355B1 (pt) 2012-05-07 2020-12-29 Shell Internationale Research Maatschappij B.V. processo contínuo ou semicontínuo para tratar biomassa
DE102012207921A1 (de) 2012-05-11 2013-11-14 Evonik Industries Ag Mehrstufiges Syntheseverfahren mit Synthesegas
AU2013262757B2 (en) 2012-05-17 2015-06-25 Shell Internationale Research Maatschappij B.V. Process for producing volatile organic compounds from biomass material
AU2013262758B9 (en) 2012-05-17 2015-11-12 Shell Internationale Research Maatschappij B.V. Process for producing volatile organic compounds from biomass material
KR101402108B1 (ko) * 2012-06-19 2014-06-02 인하대학교 산학협력단 불포화 지방산을 생산하는 재조합 대장균, 및 이를 이용한 불포화 지방산의 제조방법
US9347076B2 (en) 2012-06-21 2016-05-24 Lanzatech New Zealand Limited Recombinant microorganisms that make biodiesel
MY172692A (en) * 2012-07-13 2019-12-10 Calysta Inc Biorefinery system, methods and compositions thereof
WO2014015278A1 (en) * 2012-07-20 2014-01-23 Codexis, Inc. Production of fatty alcohols from engineered microorganisms
CN109182238A (zh) 2012-08-10 2019-01-11 嘉吉有限公司 用于生产脂肪酸和脂肪酸衍生产物的微生物及方法
MY195138A (en) 2012-10-15 2023-01-11 Genomatica Inc Microorganisms and Methods for Production of Specific Length Fatty Alcohols and Related Compounds
US9909153B2 (en) 2012-11-09 2018-03-06 Calysta, Inc. Compositions and methods for biological production of fatty acid derivatives
EP2922953A4 (en) 2012-11-20 2016-11-09 Shell Int Research PENTOSEFERMENTATION BY A RECOMBINANT MICROORGANISM
WO2014093505A2 (en) 2012-12-12 2014-06-19 Ls9, Inc. Acp-mediated production of fatty acid derivatives
US9512447B2 (en) 2012-12-14 2016-12-06 Codexis, Inc. Modified native beta-ketoacyl-ACP synthases and engineered microorganisms
WO2014113571A2 (en) 2013-01-16 2014-07-24 Ls9, Inc. Acyl-acp reductase with improved properties
KR102363796B1 (ko) * 2013-03-07 2022-02-16 게노마티카 인코포레이티드 재조합 숙주 세포에 의해 생성된 지방알코올 조성물들의 하류 공정
WO2014146026A1 (en) 2013-03-15 2014-09-18 Opx Biotechnologies, Inc. Bioproduction of chemicals
US10119145B2 (en) 2013-03-15 2018-11-06 Consejo Nacional De Investigaciones Cientificas Y Tecnicas (Conicet) Engineered organisms for production of novel lipids
MY203897A (en) 2013-06-14 2024-07-23 Genomatica Inc Methods of producing omega-hydroxylated fatty acid derivatives
JP6603658B2 (ja) 2013-07-19 2019-11-06 カーギル インコーポレイテッド 脂肪酸及び脂肪酸誘導体の製造のための微生物及び方法
US11408013B2 (en) 2013-07-19 2022-08-09 Cargill, Incorporated Microorganisms and methods for the production of fatty acids and fatty acid derived products
JP6459962B2 (ja) * 2013-10-21 2019-01-30 味の素株式会社 L−アミノ酸の製造法
WO2015077752A1 (en) 2013-11-25 2015-05-28 Genomatica, Inc. Methods for enhancing microbial production of specific length fatty alcohols in the presence of methanol
PL3077501T3 (pl) 2013-12-03 2022-01-31 Genomatica, Inc. Mikroorganizmy i sposoby poprawy wydajności produktu na metanolu z użyciem syntezy acetylo-coa
JP6379537B2 (ja) * 2014-03-12 2018-08-29 東ソー株式会社 組換え水素酸化細菌およびそれを用いたタンパク質製造方法
EP2944696A1 (en) 2014-05-13 2015-11-18 Evonik Degussa GmbH Method of producing organic compounds
EP2944697A1 (en) 2014-05-13 2015-11-18 Evonik Degussa GmbH Method of producing nylon
US11441130B2 (en) 2014-06-16 2022-09-13 Genomatica, Inc. Omega-hydroxylase-related fusion polypeptides with improved properties
WO2015200335A1 (en) * 2014-06-23 2015-12-30 Joule Unlimited Technologies, Inc. Engineered photosynthetic microbes and recombinant synthesis of carbon-based products
BR112017001105A2 (pt) 2014-07-18 2018-07-24 REG Life Sciences, LLC produção microbiana de dióis graxos
WO2016025673A1 (en) 2014-08-14 2016-02-18 Shell Oil Company Process for preparing furfural from biomass
WO2016025678A1 (en) 2014-08-14 2016-02-18 Shell Oil Company Process for preparing furfural from biomass
CN106573884B (zh) 2014-08-14 2018-09-28 国际壳牌研究有限公司 处理生物质以生产用于生物燃料的物质的改进方法
EP2993228B1 (en) 2014-09-02 2019-10-09 Cargill, Incorporated Production of fatty acid esters
US20170298363A1 (en) 2014-09-18 2017-10-19 Genomatica, Inc Non-natural microbial organisms with improved energetic efficiency
JP6589327B2 (ja) * 2015-03-27 2019-10-16 東ソー株式会社 組換え水素酸化細菌とそれを用いたタンパク質製造方法
EP3376859B1 (en) 2015-11-18 2021-01-06 Provivi, Inc. Microorganisms for the production of insect pheromones and related compounds
WO2017101987A1 (en) 2015-12-15 2017-06-22 REG Life Sciences, LLC Omega-hydroxylase-related fusion polypeptide variants with improved properties
ES2803208T3 (es) 2015-12-17 2021-01-25 Evonik Operations Gmbh Una célula acetogénica genéticamente modificada
RU2740758C2 (ru) 2016-05-03 2021-01-20 Шелл Интернэшнл Рисерч Маатсхаппий Б.В. Растворители на основе лигнина и способы их получения
JP2019517797A (ja) 2016-06-06 2019-06-27 プロヴィヴィ インコーポレイテッド 脂肪アルコールおよび脂肪アルデヒドの半生合成的生産
US10421951B2 (en) 2016-06-22 2019-09-24 Wisconsin Alumni Research Foundation Gene construct encoding mutant thioesterase, mutant thioesterase encoded thereby, transformed host cell containing the gene construct, and method of using them to produce medium-chain fatty acids
WO2018019867A1 (en) 2016-07-27 2018-02-01 Evonik Degussa Gmbh N-acetyl homoserine
US10662448B2 (en) 2016-10-17 2020-05-26 Xylome Corporation Compositions and methods for producing lipids and other biomaterials from grain ethanol stillage and stillage derivatives
EP3535248A1 (en) 2016-11-01 2019-09-11 Shell Internationale Research Maatschappij B.V. Process for the recovery of furfural
CN109890800B (zh) 2016-11-01 2023-05-23 国际壳牌研究有限公司 用于回收糠醛的工艺
EP3535246A1 (en) 2016-11-01 2019-09-11 Shell Internationale Research Maatschappij B.V. Process for the recovery of furfural
US10899725B2 (en) 2016-11-01 2021-01-26 Shell Oil Company Process for the recovery of furfural
WO2018144701A2 (en) 2017-02-02 2018-08-09 Cargill Incorporated Genetically modified cells that produce c6-c10 fatty acid derivatives
AU2018235765A1 (en) 2017-03-14 2019-09-26 Intrexon Corporation Methods and microorganisms for making 1,4-butanediol and derivatives thereof from C1 carbons
CN111094558A (zh) 2017-04-03 2020-05-01 基因组股份公司 对产生中链脂肪酸衍生物具有改善的活性的硫酯酶变体
WO2018213554A1 (en) 2017-05-17 2018-11-22 Provivi, Inc. Microorganisms for the production of insect pheromones and related compounds
US20210079334A1 (en) 2018-01-30 2021-03-18 Genomatica, Inc. Fermentation systems and methods with substantially uniform volumetric uptake rate of a reactive gaseous component
US10844410B2 (en) 2018-03-19 2020-11-24 Wisconsin Alumni Research Foundation Mutant thioesterases
EP3794017A4 (en) 2018-05-17 2022-03-09 Lumen Bioscience, Inc. ARTHROSPIRA PLATENSIS ORAL VACCINE DELIVERY PLATFORM
US12252513B2 (en) 2018-07-16 2025-03-18 Lumen Bioscience, Inc. Thermostable phycobiliproteins produced from recombinant arthrospira
US12098168B2 (en) 2018-08-31 2024-09-24 Genomatica, Inc. XylR mutant for improved xylose utilization or improved co-utilization of glucose and xylose preliminary
EP3670495A1 (en) 2018-12-21 2020-06-24 Clariant International Ltd Glucamide-based surfactants
EP3972962A1 (en) 2019-05-22 2022-03-30 Shell Internationale Research Maatschappij B.V. Process for the production of furfural
AU2020298626A1 (en) 2019-07-03 2022-02-24 Lumen Bioscience, Inc. Arthrospira platensis non-parenteral therapeutic delivery platform
GB2617381A (en) * 2022-04-07 2023-10-11 Phycobloom Ltd Engineered photosynthetic organisms
AU2024212235A1 (en) 2023-01-23 2025-07-03 Shell Internationale Research Maatschappij B.V. Method for treating grains to produce material useful for chemicals and biofuels

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5028539A (en) 1988-08-31 1991-07-02 The University Of Florida Ethanol production using engineered mutant E. coli
US5424202A (en) 1988-08-31 1995-06-13 The University Of Florida Ethanol production by recombinant hosts
US5000000A (en) 1988-08-31 1991-03-19 University Of Florida Ethanol production by Escherichia coli strains co-expressing Zymomonas PDC and ADH genes
US5482846A (en) 1988-08-31 1996-01-09 University Of Florida Ethanol production in Gram-positive microbes
US5602030A (en) 1994-03-28 1997-02-11 University Of Florida Research Foundation Recombinant glucose uptake system
US6428767B1 (en) 1995-05-12 2002-08-06 E. I. Du Pont De Nemours And Company Method for identifying the source of carbon in 1,3-propanediol
US6015440A (en) * 1997-10-31 2000-01-18 Board Of Regents Of The University Of Nebraska Process for producing biodiesel fuel with reduced viscosity and a cloud point below thirty-two (32) degrees fahrenheit
DE60329983D1 (de) 2002-03-01 2009-12-24 Monsanto Technology Llc Wachsestersynthase-dna-sequenz, protein und verwendungen davon
JP2007502124A (ja) 2003-08-11 2007-02-08 コデクシス, インコーポレイテッド 改良ケトレダクターゼポリペプチドおよび関連ポリヌクレオチド
US7458998B2 (en) * 2004-08-23 2008-12-02 Flint Hills Resources, L.P. Blending biodiesel with diesel fuel in cold locations
DE102004052115A1 (de) * 2004-10-26 2006-04-27 Westfälische Wilhelms-Universität Münster Mikroorganismen zur Herstellung von Fettsäureestern, Verfahren zu deren Herstellung und deren Verwendung
ES2528482T3 (es) * 2006-05-19 2015-02-10 Ls9, Inc. Producción de ácidos grasos y derivados de los mismos

Also Published As

Publication number Publication date
ES2763624T3 (es) 2020-05-29
EP2194119A2 (en) 2010-06-09
EP2157170B1 (en) 2014-01-15
WO2007136762A2 (en) 2007-11-29
EP2024491A2 (en) 2009-02-18
ES2529176T3 (es) 2015-02-17
JP5961662B2 (ja) 2016-08-02
JP5933909B2 (ja) 2016-06-15
BRPI0712205A2 (pt) 2012-02-22
JP6275203B2 (ja) 2018-02-07
EP2024491B1 (en) 2014-11-19
MX2008014603A (es) 2009-02-06
MX356086B (es) 2018-05-11
CA2650773A1 (en) 2007-11-29
JP2014207908A (ja) 2014-11-06
EP2194119A3 (en) 2010-09-22
EP2157170A1 (en) 2010-02-24
CA2650773C (en) 2014-12-02
KR20090029708A (ko) 2009-03-23
DK2840131T3 (da) 2020-01-20
AU2007254151A1 (en) 2007-11-29
JP2010505388A (ja) 2010-02-25
MX344588B (es) 2016-12-20
WO2007136762A3 (en) 2008-04-17
JP2016178943A (ja) 2016-10-13

Similar Documents

Publication Publication Date Title
ES2529176T3 (es) Producción de ácidos grasos y derivados de los mismos
CY1114010T1 (el) Φαρμακευτικο σκευασμα που περιλαμβανει ενα ή περισσοτερους εστερες φουμαρικου οξεως με μητρα διαβρωσης
ES2492497T3 (es) Perácidos alfa-ceto y métodos para su producción y uso
AR063370A1 (es) Composiciones herbicidas
ES2555781T3 (es) Aceites vegetales epoxidados como plastificantes de PVC
ES2657737T3 (es) Vector dual para la inhibición del virus de la inmunodeficiencia humana
CL2011003161A1 (es) Celula huesped microbiana oleaginosa recombinante para la produccion mejorada de acido eicosapentaenoico, la que codifica un polipeptido con actividad acil coa lisofosfolipido, metodo para elaborar aceite que comprende dicho acido graso de cadena larga.
ES2535732T3 (es) Escherichia coli productora de L-treonina y proceso para producir L-treonina usando la misma
BR112012033005A2 (pt) artigo que tem uma superfície que pode ser escrita, método para a fabricação de uma superfície de escrita e método de uso de um artigo que tem uma superfície de escrita que pode ser reescrita
AR093460A1 (es) Medios de cultivo celular
BR112012006681A2 (pt) método para produzir uma composição de ésteres de ácidos graxos, composição de ésteres de ácidos graxos método para produzir uma composição de ésteres graxos e composição de biocombustivel
PE20110480A1 (es) Microorganismos y vacunas dependientes de replicacion de aminoacidos no naturales
MX2019013171A (es) Formulaciones muco-adhesivas de liberacion controlada de levodopa y/o esteres de levodopa y sus usos.
BR112012014062A2 (pt) organismo microbiano que não ocorre naturalmente e método para produzir 1,3 bdo
BR112012028805A2 (pt) composições de endorribonuclease e métodos de uso das mesmas.
BRPI0911606A2 (pt) Polipeptídeo e métodos para produzir triacilgliceróis compreendendo ácidos graxos modificados
CL2008002020A1 (es) Metodo de modificacion de un aceite, que comprende hidrolizar gliceridos con una solucion de lipasa thermomyces lanuginosus, separar la fraccion de acido graso saturado de la fraccion de glicerido hidrolizado y esterificar los gliceridos hidrolizados en la presencia de candida antarctica lipasa b; y composicion de aceite.
EP4403632A3 (en) Antisense nucleic acids
DK2073816T3 (da) Borsyrer og estere som inhibitorer af fedtsyreamid-hydrolase
BR112016029391A2 (pt) métodos, reagentes e células para biossintetizar compostos
MX345243B (es) Produccion de dha y otros lc-pufas en plantas.
ES2488407T3 (es) Preparación farmacéutica que contiene lipasa de origen bacteriano
CL2012003644A1 (es) Polinucleotido que comprende una aciltransferasas; celula huesped que comprende dicho polinucleotido; metodo para la fabricacion de un polipeptido ; metodo para la fabricacion de acidos grasos poliinsaturados.
AR079704A1 (es) Anticuerpos anti-bv8 y sus usos
CL2011003104A1 (es) Metodo para la elaboracion de acidos grasos no saturados, basado en el cultivo de una celula que expresa un polipeptido heterologo con actividad esaturasa/enoil-coa reductasa celula huesped, complejo elongasa que comprende dicho polipeptido y uso de la misma.