PL3077501T3 - Mikroorganizmy i sposoby poprawy wydajności produktu na metanolu z użyciem syntezy acetylo-coa - Google Patents

Mikroorganizmy i sposoby poprawy wydajności produktu na metanolu z użyciem syntezy acetylo-coa

Info

Publication number
PL3077501T3
PL3077501T3 PL14868117T PL14868117T PL3077501T3 PL 3077501 T3 PL3077501 T3 PL 3077501T3 PL 14868117 T PL14868117 T PL 14868117T PL 14868117 T PL14868117 T PL 14868117T PL 3077501 T3 PL3077501 T3 PL 3077501T3
Authority
PL
Poland
Prior art keywords
organisms
acetyl
methanol
micro
ways
Prior art date
Application number
PL14868117T
Other languages
English (en)
Inventor
Robin E. Osterhout
Anthony P. Burgard
Priti Pharkya
Stefan Andrae
Original Assignee
Genomatica, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genomatica, Inc. filed Critical Genomatica, Inc.
Publication of PL3077501T3 publication Critical patent/PL3077501T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14—Fungi; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P5/00—Preparation of hydrocarbons or halogenated hydrocarbons
    • C12P5/02—Preparation of hydrocarbons or halogenated hydrocarbons acyclic
    • C12P5/026—Unsaturated compounds, i.e. alkenes, alkynes or allenes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/001—Amines; Imines
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/005—Amino acids other than alpha- or beta amino acids, e.g. gamma amino acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/10—Nitrogen as only ring hetero atom
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C12P7/18—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic polyhydric
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/42—Hydroxy-carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/44—Polycarboxylic acids
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E50/00—Technologies for the production of fuel of non-fossil origin
    • Y02E50/30—Fuel from waste, e.g. synthetic alcohol or diesel

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Mycology (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Botany (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
PL14868117T 2013-12-03 2014-11-25 Mikroorganizmy i sposoby poprawy wydajności produktu na metanolu z użyciem syntezy acetylo-coa PL3077501T3 (pl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201361911414P 2013-12-03 2013-12-03
US201461945056P 2014-02-26 2014-02-26
PCT/US2014/067287 WO2015084633A1 (en) 2013-12-03 2014-11-25 Microorganisms and methods for improving product yields on methanol using acetyl-coa synthesis
EP14868117.4A EP3077501B1 (en) 2013-12-03 2014-11-25 Microorganisms and methods for improving product yields on methanol using acetyl-coa synthesis

Publications (1)

Publication Number Publication Date
PL3077501T3 true PL3077501T3 (pl) 2022-01-31

Family

ID=53273985

Family Applications (1)

Application Number Title Priority Date Filing Date
PL14868117T PL3077501T3 (pl) 2013-12-03 2014-11-25 Mikroorganizmy i sposoby poprawy wydajności produktu na metanolu z użyciem syntezy acetylo-coa

Country Status (5)

Country Link
US (3) US10808262B2 (pl)
EP (4) EP3967747B1 (pl)
PL (1) PL3077501T3 (pl)
SI (1) SI3077501T1 (pl)
WO (1) WO2015084633A1 (pl)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2791342B1 (en) * 2011-12-16 2020-04-29 Braskem S.A. Modified microorganisms and methods of making butadiene using same
KR20150108367A (ko) * 2013-01-21 2015-09-25 세키스이가가쿠 고교가부시키가이샤 재조합 세포, 및 1,4-부탄디올의 생산 방법
WO2015077752A1 (en) 2013-11-25 2015-05-28 Genomatica, Inc. Methods for enhancing microbial production of specific length fatty alcohols in the presence of methanol
PL3077501T3 (pl) 2013-12-03 2022-01-31 Genomatica, Inc. Mikroorganizmy i sposoby poprawy wydajności produktu na metanolu z użyciem syntezy acetylo-coa
EP3314002A4 (en) * 2015-06-23 2019-07-10 Genomatica, Inc. MICRO-ORGANISMS AND METHOD FOR PRODUCING BIOSYNTHETIZED TARGET PRODUCTS WITH A REDUCED SUBSTANCE OF BY-PRODUCTS
JP6608936B2 (ja) * 2015-09-02 2019-11-20 積水化学工業株式会社 組換え細胞、組換え細胞の製造方法、並びに、１，４−ブタンジオールの生産方法
MX2023003058A (es) * 2015-10-13 2023-04-05 Lanzatech Nz Inc Bacteria diseñada por ingeniería genética que comprende una trayectoria de fermentación que genera energía.
WO2017210381A1 (en) * 2016-06-02 2017-12-07 William Marsh Rice University Bioconversion of 1-carbon feedstocks to chemicals and fuels
CN109536240B (zh) * 2019-01-17 2021-06-22 常州碳孚新材料技术有限公司 一种含亲油性石墨烯和中间相碳微球的润滑油添加剂及其制备方法
BR112022021838A2 (pt) * 2020-04-29 2022-12-13 Lanzatech Inc Microrganismo, método para produzir ss-cetoadipato, e, método de produção de um polímero
CN118251496A (zh) * 2021-07-12 2024-06-25 摩珈生物科技有限公司 用于高碳和高能效下燃料和化学品生产的羧酸平台
CN113528366B (zh) * 2021-07-15 2023-12-08 洛阳华荣生物技术有限公司 一种产beta-丙氨酸酵母菌及其构建方法
GB202118029D0 (en) 2021-12-13 2022-01-26 Mitsubishi Chemical Uk Ltd A process for purification of crude methyl methacrylate
CN114196609B (zh) * 2021-12-31 2023-06-23 淮阴工学院 从乳酸合成纯聚乳酸的大肠杆菌工程菌及其制备方法和应用
CN114806998B (zh) * 2022-06-27 2022-09-27 中国农业科学院北京畜牧兽医研究所 产葡萄糖的罗尔斯通氏菌工程菌及发酵生产方法
CN116064546B (zh) * 2022-11-21 2024-08-27 中国科学院天津工业生物技术研究所 一种调控丁酸生产的启动子及其应用
EP4735580A1 (en) * 2023-06-28 2026-05-06 Westlake University Regulation of cellular energy metabolism by lipoate protein ligase and its applications
CN117683646B (zh) * 2023-12-13 2025-07-11 天津大学 一种固碳破囊壶菌菌株的构建方法
CN117965590B (zh) * 2024-01-18 2024-09-17 华南理工大学 一种生产四氢嘧啶的菌株及其构建方法和应用
TW202607136A (zh) * 2024-06-27 2026-02-16 德商巴地斯顏料化工廠 自甲醇製備c6-c26脂肪醇
CN120624325B (zh) * 2025-08-13 2026-02-24 北京微构工场生物技术有限公司 一种高效利用乙酸合成pha的菌株及其应用

Family Cites Families (115)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3090816A (en) 1963-05-21 Isomerization of alkylene oxide
US3090815A (en) 1963-05-21 Isomerization of alkylene oxide
US3542883A (en) 1966-08-10 1970-11-24 Costin Nenitescu Process for isomerization of 1,2-alkylene oxides
JPS5513230A (en) 1978-07-14 1980-01-30 Nissan Chem Ind Ltd Isomerization of unsaturated alcohol
IL101120A (en) 1991-03-08 1996-10-31 Tokyo Gas Co Ltd Preparation of compounds marked C31
US6331428B1 (en) 1997-07-09 2001-12-18 Ajinomoto Co., Inc. Hexulose phosphate isomerase gene
JP2000069976A (ja) 1998-09-02 2000-03-07 Ajinomoto Co Inc メタノール脱水素酵素の新規活性促進因子及びその遺伝子
AU3482200A (en) 1999-02-02 2000-08-25 Bernhard Palsson Methods for identifying drug targets based on genomic sequence data
JP2002017351A (ja) 2000-07-07 2002-01-22 Ajinomoto Co Inc ホスホヘキシュロイソメラーゼ及びその遺伝子
JP4776146B2 (ja) 2001-01-10 2011-09-21 ザ・ペン・ステート・リサーチ・ファンデーション 細胞代謝をモデル化する方法及びシステム
US7127379B2 (en) 2001-01-31 2006-10-24 The Regents Of The University Of California Method for the evolutionary design of biochemical reaction networks
CA2439260C (en) 2001-03-01 2012-10-23 The Regents Of The University Of California Models and methods for determining systemic properties of regulated reaction networks
BR0209491A (pt) 2001-05-07 2004-10-13 Cargil Inc Processo para preparar ácidos carboxìlicos e derivados destes
RU2299907C2 (ru) 2001-09-06 2007-05-27 Адзиномото Ко., Инк. Бактерия рода bacillus, продуцирующая l-аминокислоту, и способ получения l-аминокислоты
SE0200857D0 (sv) 2002-03-19 2002-03-19 Forskarpatent I Syd Ab Metabolic engineering for improved xylose utilisation of saccharomyces cerevisiae
US20030224363A1 (en) 2002-03-19 2003-12-04 Park Sung M. Compositions and methods for modeling bacillus subtilis metabolism
CA2480216A1 (en) 2002-03-29 2003-10-09 Genomatica, Inc. Human metabolic models and methods
US6911332B2 (en) 2002-06-12 2005-06-28 Ajinomoto Co., Inc. Isolated polynucleotides encoding d-arabino-3-hexulose-6-phosphate synthases from Methylophilus methylotrophus
US7856317B2 (en) 2002-06-14 2010-12-21 Genomatica, Inc. Systems and methods for constructing genomic-based phenotypic models
JP4418793B2 (ja) 2002-07-10 2010-02-24 ザ ペン ステート リサーチ ファウンデーション 遺伝子ノックアウト戦略を決定する方法
CA2500761C (en) 2002-10-15 2012-11-20 Bernhard O. Palsson Methods and systems to identify operational reaction pathways
DE102004001674B4 (de) 2003-01-29 2019-01-24 Ajinomoto Co., Inc. Verfahren zur Herstellung von L-Lysin unter Einsatz von Methanol verwertenden Bakterien
JP2004261150A (ja) 2003-03-04 2004-09-24 Ajinomoto Co Inc 目的物質の製造法
RU2004124226A (ru) * 2004-08-10 2006-01-27 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО АГРИ) (RU) Использование фосфокетолазы для продукции полезных метаболитов
KR100892577B1 (ko) * 2004-08-10 2009-04-08 아지노모토 가부시키가이샤 유용한 대사산물을 생산하기 위한 포스포케톨라제의 용도
AU2006287257A1 (en) 2005-09-09 2007-03-15 Genomatica, Inc. Methods and organisms for the growth-coupled production of succinate
ES2528482T3 (es) 2006-05-19 2015-02-10 Ls9, Inc. Producción de ácidos grasos y derivados de los mismos
DE102006025821A1 (de) 2006-06-02 2007-12-06 Degussa Gmbh Ein Enzym zur Herstellung von Mehylmalonatsemialdehyd oder Malonatsemialdehyd
EP2064321B1 (en) 2006-08-30 2016-03-09 Cargill, Incorporated Beta-alanine/alpha-ketoglutarate aminotransferase for 3-hydroxypropionic acid production
WO2008091627A2 (en) 2007-01-22 2008-07-31 Genomatica, Inc. Methods and organisms for growth-coupled production of 3-hydroxypropionic acid
TWI568847B (zh) 2007-03-16 2017-02-01 奇諾麥提卡公司 用於１，４-丁二醇及其前驅物之生物合成的組合物及方法
AT505251B1 (de) 2007-05-30 2009-09-15 Vogelbusch Gmbh Verfahren zum umwandeln von xylose oder xylose enthaltenden substratlísungen
US8502000B2 (en) 2007-06-27 2013-08-06 H R D Corporation Method of making glycerol
US7947483B2 (en) 2007-08-10 2011-05-24 Genomatica, Inc. Methods and organisms for the growth-coupled production of 1,4-butanediol
WO2009045637A2 (en) 2007-08-10 2009-04-09 Genomatica, Inc. Methods for the synthesis of acrylic acid and derivatives from fumaric acid
EP2062967A1 (en) 2007-11-21 2009-05-27 Technical University of Denmark Genetically engineered aspergillus
US8183028B2 (en) 2007-12-21 2012-05-22 Ls9, Inc. Methods and compositions for producing olefins
CN107090424A (zh) 2008-01-22 2017-08-25 基因组股份公司 利用合成气或其它气态碳源和甲醇的方法和有机体
WO2009110984A2 (en) 2008-02-29 2009-09-11 Lantheus Medical Imaging, Inc. Contrast agents for applications including perfusion imaging
EP3450550A1 (en) 2008-03-05 2019-03-06 Genomatica, Inc. Primary alcohol producing organisms
PL2265709T3 (pl) 2008-03-27 2018-05-30 Genomatica, Inc. Mikroorganizmy do produkcji kwasu adypinowego i innych związków
JP2011518564A (ja) 2008-04-23 2011-06-30 ダニスコ・ユーエス・インク 改良された微生物によるイソプレン産出用のイソプレンシンターゼ変異体
WO2009135074A2 (en) 2008-05-01 2009-11-05 Genomatica, Inc. Microorganisms for the production of methacrylic acid
WO2009155382A1 (en) 2008-06-17 2009-12-23 Genomatica, Inc. Microorganisms and methods for the biosynthesis of fumarate, malate, and acrylate
US20100021978A1 (en) 2008-07-23 2010-01-28 Genomatica, Inc. Methods and organisms for production of 3-hydroxypropionic acid
CA2735883C (en) 2008-09-10 2020-05-05 Genomatica, Inc. Microorganisms for the production of 1,4-butanediol
WO2010031079A1 (en) 2008-09-15 2010-03-18 Danisco Us Inc. Systems using cell culture for production of isoprene
US20100184173A1 (en) 2008-11-14 2010-07-22 Genomatica, Inc. Microorganisms for the production of methyl ethyl ketone and 2-butanol
CA2746952A1 (en) 2008-12-16 2010-06-24 Genomatica, Inc. Microorganisms and methods for conversion of syngas and other carbon sources to useful products
WO2010104938A1 (en) 2009-03-10 2010-09-16 Athena Biotechnologies, Inc. Reducing carbon dioxide production and increasing ethanol yield during microbial ethanol fermentation
EP3865569B1 (en) 2009-04-30 2023-10-04 Genomatica, Inc. Organisms for the production of 1,3-butanediol
BRPI1013505A2 (pt) 2009-04-30 2018-02-14 Genomatica Inc organismos para a produção de isopropanol, n-butanol, e isobutanol
WO2010129936A1 (en) 2009-05-07 2010-11-11 Genomatica, Inc. Microorganisms and methods for the biosynthesis of adipate, hexamethylenediamine and 6-aminocaproic acid
KR20120036851A (ko) 2009-05-15 2012-04-18 게노마티카 인코포레이티드 사이클로헥사논의 제조를 위한 유기체
BRPI1010581A2 (pt) 2009-06-04 2016-11-08 Genomatica Inc micro-organismos para a produção de 1,4-butanodiol e métodos relacionados
PL2438036T3 (pl) 2009-06-04 2017-09-29 Genomatica, Inc. Sposób oddzielania składników brzeczki fermentacyjnej
WO2010144746A2 (en) 2009-06-10 2010-12-16 Genomatica, Inc. Microorganisms and methods for carbon-efficient biosynthesis of mek and 2-butanol
DK2462221T3 (en) 2009-08-05 2017-05-22 Genomatica Inc SEMISYNTHETIC TEREPHTHALIC ACID BY MICRO-ORGANISMS PRODUCING MUCONIC ACID
EP2467490A1 (en) * 2009-08-21 2012-06-27 Mascoma Corporation Production of propanols, alcohols, and polyols in consolidated bioprocessing organisms
US8715971B2 (en) 2009-09-09 2014-05-06 Genomatica, Inc. Microorganisms and methods for the co-production of isopropanol and 1,4-butanediol
AU2010306785B2 (en) 2009-10-13 2016-01-14 Genomatica, Inc. Microorganisms for the production of 1,4-butanediol, 4-hydroxybutanal, 4-hydroxybutyryl-CoA, putrescine and related compounds, and methods related thereto
US20110097767A1 (en) 2009-10-23 2011-04-28 Priti Pharkya Microorganisms for the production of aniline
US8530210B2 (en) 2009-11-25 2013-09-10 Genomatica, Inc. Microorganisms and methods for the coproduction 1,4-butanediol and gamma-butyrolactone
CN102753698A (zh) 2009-12-10 2012-10-24 基因组股份公司 合成气或其他气态碳源和甲醇转化为1,3-丁二醇的方法和有机体
CN102834508A (zh) 2010-01-29 2012-12-19 基因组股份公司 用于生物合成对甲苯甲酸和对苯二甲酸的微生物和方法
US8048661B2 (en) 2010-02-23 2011-11-01 Genomatica, Inc. Microbial organisms comprising exogenous nucleic acids encoding reductive TCA pathway enzymes
EP2558582A4 (en) 2010-04-13 2013-12-04 Genomatica Inc MICROORGANISMS AND PROCESSES FOR THE PRODUCTION OF ETHYLENE GLYCOL
US9023636B2 (en) 2010-04-30 2015-05-05 Genomatica, Inc. Microorganisms and methods for the biosynthesis of propylene
KR20190006103A (ko) 2010-05-05 2019-01-16 게노마티카 인코포레이티드 부타디엔을 생합성하기 위한 미생물 및 방법
US20110306107A1 (en) * 2010-06-09 2011-12-15 Raymond Edward Kalisz Hardened mycelium structure and method
US8871488B2 (en) 2010-06-18 2014-10-28 Butamax Advanced Biofuels Llc Recombinant host cells comprising phosphoketolases
US8987431B2 (en) 2010-07-01 2015-03-24 Coskata, Inc. Essential genes encoding conserved metabolic pathway function in autotrophic solventogenic clostridial species
WO2012018624A2 (en) 2010-07-26 2012-02-09 Genomatica, Inc. Microorganisms and methods for the biosynthesis of aromatics, 2,4-pentadienoate and 1,3-butadiene
WO2012082978A1 (en) 2010-12-17 2012-06-21 Genomatica, Inc. Microorganisms and methods for the production of 1.4- cyclohexanedimethanol
CN103328631B (zh) 2011-01-20 2017-04-26 丰田自动车株式会社 重组酵母和使用该重组酵母的物质生产方法
BR112013019811A2 (pt) 2011-02-02 2017-02-21 Genomatica Inc processo para a produção de butadieno e organismo microbiano que não ocorre naturalmente.
US9416364B2 (en) 2011-02-07 2016-08-16 William Marsh Rice University Reverse beta oxidation pathway
US9790521B2 (en) 2011-03-24 2017-10-17 Butamax Advanced Biofuels Llc Host cells and methods for production of isobutanol
US9133487B2 (en) 2011-04-01 2015-09-15 Genomatica, Inc. Microorganisms for producing methacrylic acid and methacrylate esters and methods related thereto
EP2702140B1 (en) 2011-04-29 2018-10-31 Danisco US Inc. Recombinant microorganisms for enhanced production of mevalonate, isoprene, and isoprenoids
US8617862B2 (en) 2011-06-22 2013-12-31 Genomatica, Inc. Microorganisms for producing propylene and methods related thereto
WO2012177619A2 (en) 2011-06-22 2012-12-27 Genomatica, Inc. Microorganisms for producing 1,3-butanediol and methods related thereto
AU2012273005A1 (en) 2011-06-22 2013-05-09 Genomatica, Inc. Microorganism for producing primary alcohols and related compounds and methods related thereto
US9169486B2 (en) 2011-06-22 2015-10-27 Genomatica, Inc. Microorganisms for producing butadiene and methods related thereto
WO2012177983A2 (en) 2011-06-22 2012-12-27 Genomatica, Inc. Microorganisms for producing ethylene glycol and methods related thereto
US20130034884A1 (en) 2011-06-22 2013-02-07 Genomatica, Inc. Microorganisms for producing 1,4-butanediol and methods related thereto
AU2012273093A1 (en) 2011-06-22 2013-05-02 Genomatica, Inc. Microorganisms for producing 6-aminocaproic acid
WO2012177599A2 (en) 2011-06-22 2012-12-27 Genomatica, Inc. Microorganisms for producing n-propanol 1, 3-propanediol, 1,2-propanediol or glycerol and methods related thereto
WO2013003432A1 (en) 2011-06-29 2013-01-03 Genomatica, Inc. Microorganisms for producing succinate and methods related thereto
RS54444B1 (sr) 2011-07-12 2016-06-30 Scientist Of Fortune S.A. Rekombinantni mikroorganizmi za proizvodnju korisnih metabolita
BR112014001174A2 (pt) 2011-07-20 2017-02-21 Genomatica Inc métodos para aumento de rendimentos de produto
CN103890185A (zh) 2011-08-19 2014-06-25 基因组股份公司 用于生产2,4-戊二烯酸、丁二烯、丙烯、1,3-丁二醇和相关醇的微生物和方法
EP2753699A4 (en) 2011-09-08 2015-08-19 Genomatica Inc EUKARYOTIC ORGANISMS AND METHOD FOR THE PRODUCTION OF 1,3-BANDANDIOL
KR20140070605A (ko) 2011-09-16 2014-06-10 게노마티카 인코포레이티드 알켄을 생산하기 위한 유기체 및 방법
BR112014008278A2 (pt) 2011-10-07 2017-04-18 Danisco Us Inc utilização de fosfocetolase na produção de mevalonato, precursores isoprenoides e isopreno
US8349587B2 (en) 2011-10-31 2013-01-08 Ginkgo Bioworks, Inc. Methods and systems for chemoautotrophic production of organic compounds
WO2013067432A1 (en) 2011-11-02 2013-05-10 Genomatica, Inc. Microorganisms and methods for the production of caprolactone
KR102021914B1 (ko) 2011-11-09 2019-09-17 아미리스 인코퍼레이티드 아세틸-코엔자임 a로부터 유래되는 이소프레노이드의 제조 방법
BR112013016373B1 (pt) 2011-11-11 2021-05-18 Ajinomoto Co., Inc método para produzir uma substância alvo
WO2013071226A1 (en) 2011-11-11 2013-05-16 Genomatica, Inc. Eukaryotic organisms and methods for increasing the availability of cytosolic acetyl-coa, and for producing 1,3-butanediol
GB201201178D0 (en) 2012-01-25 2012-03-07 Sinvent As Novel enzymes
WO2013181647A2 (en) 2012-06-01 2013-12-05 Danisco Us Inc. Compositions and methods of producing isoprene and/or industrrial bio-products using anaerobic microorganisms
CN105121637B (zh) 2012-11-20 2019-12-24 拉勒曼德匈牙利流动管理有限责任公司 酿酒酵母中替代甘油形成的消耗电子的乙醇生产途径
KR20150108367A (ko) 2013-01-21 2015-09-25 세키스이가가쿠 고교가부시키가이샤 재조합 세포, 및 1,4-부탄디올의 생산 방법
US20140273164A1 (en) * 2013-03-14 2014-09-18 The Regents Of The University Of California Non-co2 evolving metabolic pathway for chemical production
US20160017339A1 (en) 2013-03-14 2016-01-21 The Regents Of The University Of California Non-co2 evolving metabolic pathway for chemical production
CN105189772B (zh) 2013-03-15 2019-09-13 阿迈瑞斯公司 磷酸转酮酶和磷酸转乙酰酶生产乙酰-辅酶a衍生化合物的用途
US11753656B2 (en) * 2013-08-15 2023-09-12 Lallemand Hungary Liquidity Management Llc Methods for the improvement of product yield and production in a microorganism through glycerol recycling
PL3077501T3 (pl) 2013-12-03 2022-01-31 Genomatica, Inc. Mikroorganizmy i sposoby poprawy wydajności produktu na metanolu z użyciem syntezy acetylo-coa
EP3222324B1 (en) * 2016-03-23 2020-05-13 Wayne State University Valproate as a topical anti-fungal treatment
JP2020013009A (ja) 2018-07-19 2020-01-23 株式会社フジクラ 光コネクタ、及び、光コネクタ用交換部品ユニット
KR102724903B1 (ko) 2019-07-04 2024-11-01 삼성전기주식회사 적층 세라믹 커패시터
WO2022217064A2 (en) 2021-04-09 2022-10-13 Genomatica, Inc. Phosphoketolase variants and methods of use
JP7199792B1 (ja) 2021-07-15 2023-01-06 Thk株式会社 スライドレールユニット
JP2025013009A (ja) 2023-07-14 2025-01-24 株式会社マキタ 携帯用切断機

Also Published As

Publication number Publication date
EP3967747B1 (en) 2023-11-08
US20170159075A1 (en) 2017-06-08
US12529078B2 (en) 2026-01-20
EP3967747C0 (en) 2023-11-08
EP3077501A1 (en) 2016-10-12
EP4296364B1 (en) 2025-12-03
EP3077501B1 (en) 2021-07-28
EP4296364A3 (en) 2024-08-21
EP4296364C0 (en) 2025-12-03
EP3077501A4 (en) 2017-08-16
SI3077501T1 (sl) 2022-02-28
WO2015084633A1 (en) 2015-06-11
US10808262B2 (en) 2020-10-20
EP4717777A2 (en) 2026-04-01
US20240294950A1 (en) 2024-09-05
US20210332393A1 (en) 2021-10-28
EP3967747A1 (en) 2022-03-16
EP4296364A2 (en) 2023-12-27

Similar Documents

Publication Publication Date Title
PL2959163T3 (pl) Siłownik i sposób udoskonalenia siłownika
PT3591047T (pt) Pepmixes para gerar ctls multivirais com larga especifidade
FI11677U1 (fi) Uusiutuva hiilivetykoostumus
DK2984424T3 (da) Forbedringer i køleskabe
PL2468875T3 (pl) Zintegrowany sposób wytwarzania biopaliw
PL3260558T3 (pl) Nowe kompozycje i sposoby poprawy specyficzności pcr
PL2630108T3 (pl) Sposób wytwarzania 2,3,3,3-tetrafluoropropenu
SI3077501T1 (sl) Mikroorganizmi in metode za izboljšanje donosa izdelkov z uporabo sinteze acetil-coa
PL2803818T3 (pl) Sposób sterowania wrębiarką
FI11676U1 (fi) Uusiutuva hiilivetykoostumus
DK2890819T4 (da) Tane med udvidelsesorganer
GB2516942B (en) Text to Speech Conversion
PL2980053T3 (pl) Sposób wytwarzania butadienu
PL2617086T3 (pl) Akumulator, skrzynka akumulatora i sposób wytwarzania akumulatora
PL2984321T3 (pl) Sposób identyfikacji mieszanek paliwowych
FI20135946L (fi) Rinnakkainen ratkaisun muodostaminen
EP2983717A4 (en) TOPICAL USEFUL COMPOSITION
EP3078042C0 (en) DOUBLE CUT DOUBLE CLOSING SWITCH MODULE WITH INDEPENDENT BLADES
PL2769662T3 (pl) Zmywarka do naczyń i sposób obsługi zmywarki do naczyń
FI20135236A7 (fi) Haudutin
DK2824325T3 (da) Tårnsektionsopbevaring
GB2515059B (en) Mapping cells to symbols
EP2975014A4 (en) METHANOL PRODUCTION PLANT AND BENZENE SYNTHESIS PLANT
ES1074133Y (es) Caja-estuche para guardar ordenadamente cosas
TH1501001771A (th) การแปรสภาพชีวมวล