ES2532030B2 - Método de medición del tono vascular ex vivo y cámara de flujo - Google Patents

Método de medición del tono vascular ex vivo y cámara de flujo Download PDF

Info

Publication number
ES2532030B2
ES2532030B2 ES201300866A ES201300866A ES2532030B2 ES 2532030 B2 ES2532030 B2 ES 2532030B2 ES 201300866 A ES201300866 A ES 201300866A ES 201300866 A ES201300866 A ES 201300866A ES 2532030 B2 ES2532030 B2 ES 2532030B2
Authority
ES
Spain
Prior art keywords
measuring
vascular tone
flow chamber
vessel
tone
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES201300866A
Other languages
English (en)
Other versions
ES2532030A1 (es
Inventor
María Teresa TEJERINA SÁNCHEZ
Santiago REDONDO BLASCO
Úrsula Fabiola MEDINA MORENO
Jorge NAVARRO DORADO
Marta RAMAJO MATESANZ
Alexis CANTIZANO GONZÁLEZ
Mario CASTRO PONCE
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Complutense University of Madrid
Original Assignee
Complutense University of Madrid
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Complutense University of Madrid filed Critical Complutense University of Madrid
Priority to ES201300866A priority Critical patent/ES2532030B2/es
Publication of ES2532030A1 publication Critical patent/ES2532030A1/es
Application granted granted Critical
Publication of ES2532030B2 publication Critical patent/ES2532030B2/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/49—Blood

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Ecology (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

Método de medición del tono vascular ex vivo y cámara de flujo.#La presente invención se refiere a un método de medición del tono vascular ex vivo que comprende: perfundir un flujo constante de una suspensión celular en un circuito abierto que incluye un vaso cuyo tono se desea estudiar, cerrar el circuito, perfundir una solución nutricia de Krebs en el circuito cerrado y aplicar una presión transmural constante, añadir una sustancia vasoactiva y registrar las variaciones de diámetro del vaso mediante un sistema de captación de imágenes situado perpendicularmente al vaso y acoplado a un microscopio.#La invención también se refiere a una cámara de flujo en la que realizar el método de medición del tono vascular que incluye dos capilares de vidrio, un baño, una bomba de infusión, un sistema de presión hidrostática, un manómetro, un sistema de termorregulación de la temperatura del baño y de las soluciones y/o suspensiones utilizadas, un sistema de captación de imágenes y un microscopio.

Description

imagen1
imagen2
imagen3
imagen4
imagen5
imagen6
imagen7
imagen8

Claims (1)

  1. imagen1
    imagen2
ES201300866A 2013-09-20 2013-09-20 Método de medición del tono vascular ex vivo y cámara de flujo Active ES2532030B2 (es)

Priority Applications (1)

Application Number Priority Date Filing Date Title
ES201300866A ES2532030B2 (es) 2013-09-20 2013-09-20 Método de medición del tono vascular ex vivo y cámara de flujo

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES201300866A ES2532030B2 (es) 2013-09-20 2013-09-20 Método de medición del tono vascular ex vivo y cámara de flujo

Publications (2)

Publication Number Publication Date
ES2532030A1 ES2532030A1 (es) 2015-03-23
ES2532030B2 true ES2532030B2 (es) 2015-12-28

Family

ID=52683008

Family Applications (1)

Application Number Title Priority Date Filing Date
ES201300866A Active ES2532030B2 (es) 2013-09-20 2013-09-20 Método de medición del tono vascular ex vivo y cámara de flujo

Country Status (1)

Country Link
ES (1) ES2532030B2 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116045878B (zh) * 2023-03-07 2023-06-20 中国人民解放军军事科学院军事医学研究院 一种血管管径变化的检测方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4535786A (en) * 1983-07-25 1985-08-20 Kater John A R Measurement of body fluid chemistry
DE3774680D1 (de) * 1986-12-22 1992-01-02 Siemens Ag Anordnung zur untersuchung eines fluessigen mediums und verfahren zum betrieb der anordnung.
US5078135A (en) * 1989-05-31 1992-01-07 Board Of Regents, The University Of Texas System Apparatus for in vivo analysis of biological compounds in blood or tissue by microdialysis and mass spectrometry
US6607501B2 (en) * 2001-05-14 2003-08-19 Reynolds G. Gorsuch Process and apparatus for utilization of in vivo extracted plasma with tissue engineering devices, bioreactors, artificial organs, and cell therapy applications
AU2006242377B2 (en) * 2005-04-29 2011-12-08 Dtherapeutics, Llc Devices, systems and methods for isometric and isotonic contraction of blood vessels using an isovolumic myograph

Also Published As

Publication number Publication date
ES2532030A1 (es) 2015-03-23

Similar Documents

Publication Publication Date Title
BR112017002862A2 (pt) método, e, sistema
JP2016523513A5 (es)
WO2018223105A3 (en) HYDROGEL-MEDIATED MICROFLUIDIC SWEAT SEQUESTRATION FOR PORTABLE MAN-DEVICE INTERFACES
BR112015028729A2 (pt) lente oftálmica com um sistema microfluídico
BR112018014118A2 (pt) sistema e processo de medida de uma propriedade de escoamento de um fluido no seio de um meio poroso
EA201592155A1 (ru) Устройство для горизонтального проточного анализа
NZ726748A (en) A method of observing an auto fluorescence image of a cancer related substance through a fluorescence microscope
RU2018121343A (ru) Устройство для сбора и диагностики жидкостей организма
MX372822B (es) Dispositivo de preparación y extracción de muestras.
EA201201022A1 (ru) Устройство мониторинга пространственного свертывания крови и ее компонентов
Cepeda et al. Experimental evaluation and computational modeling of tissue damage from low-flow push–pull perfusion sampling in vivo
CL2018002477A1 (es) Sistema y método para la detección y digitalización del hormigón en estado fresco usando tecnología infraroja y funciones matemáticas de tendencia.
ES2582868T3 (es) Procedimiento de tarado hidráulico de un sistema de calefacción
RU2016149554A (ru) Способ измерения вязкости
WO2013124727A3 (en) Perfusion device, corresponding apparatus using said perfusion device and method to analyze the thrombotic-ischemic and hemorrhagic pathology
BR112018013233A8 (pt) Método e dispositivo para calcular a pressão arterial hemodinâmica óptica
BR112017028098A2 (en) methods and apparatus for determining the production of wellhead pumps
AR098914A1 (es) Sistema de prueba de recipientes
ES2532030A1 (es) Método de medición del tono vascular ex vivo y cámara de flujo
Bonetti et al. Analysis of a temperature-dependent model for adhesive contact with friction
KR101401113B1 (ko) 증기압 측정장치
CL2017001694A1 (es) Cuantificación de partículas microscópicas de alta precisión
EP2799139A3 (en) Fluid stop for measured sample containment
ES2540120B2 (es) Procedimiento de doble inclusión para el estudio histológico y/o de localización de marcadores moleculares en especímenes pluricelulares de dimensiones microscópicas
Bellini et al. The usefulness of cadaveric fungi as an investigation tool

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 2532030

Country of ref document: ES

Kind code of ref document: B2

Effective date: 20151228