ES2613761T3 - Sistema protésico para el reemplazo de la válvula cardíaca - Google Patents

Sistema protésico para el reemplazo de la válvula cardíaca Download PDF

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Publication number
ES2613761T3
ES2613761T3 ES13812152.0T ES13812152T ES2613761T3 ES 2613761 T3 ES2613761 T3 ES 2613761T3 ES 13812152 T ES13812152 T ES 13812152T ES 2613761 T3 ES2613761 T3 ES 2613761T3
Authority
ES
Spain
Prior art keywords
segments
ring
prosthetic
valve
heart valve
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES13812152.0T
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English (en)
Inventor
Giovanni Righini
Sarah Zanon
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Innovheart SRL
Original Assignee
Innovheart SRL
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Filing date
Publication date
Priority claimed from IT000636A external-priority patent/ITBO20120636A1/it
Application filed by Innovheart SRL filed Critical Innovheart SRL
Application granted granted Critical
Publication of ES2613761T3 publication Critical patent/ES2613761T3/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
    • A61F2/2412—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body with soft flexible valve members, e.g. tissue valves shaped like natural valves
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/22—Implements for squeezing-off ulcers or the like on inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; for invasive removal or destruction of calculus using mechanical vibrations; for removing obstructions in blood vessels, not otherwise provided for
    • A61B17/221—Gripping devices in the form of loops or baskets for gripping calculi or similar types of obstructions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
    • A61F2/2427—Devices for manipulating or deploying heart valves during implantation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
    • A61F2/2442—Annuloplasty rings or inserts for correcting the valve shape; Implants for improving the function of a native heart valve
    • A61F2/2445—Annuloplasty rings in direct contact with the valve annulus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
    • A61F2/2442—Annuloplasty rings or inserts for correcting the valve shape; Implants for improving the function of a native heart valve
    • A61F2/2454—Means for preventing inversion of the valve leaflets, e.g. chordae tendineae prostheses
    • A61F2/2457—Chordae tendineae prostheses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
    • A61F2/2442—Annuloplasty rings or inserts for correcting the valve shape; Implants for improving the function of a native heart valve
    • A61F2/2466—Delivery devices therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/00234—Surgical instruments, devices or methods for minimally invasive surgery
    • A61B2017/00238—Type of minimally invasive operation
    • A61B2017/00243—Type of minimally invasive operation cardiac
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/00234—Surgical instruments, devices or methods for minimally invasive surgery
    • A61B2017/00358—Snares for grasping
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B2017/00743—Type of operation; Specification of treatment sites
    • A61B2017/00778—Operations on blood vessels
    • A61B2017/00783—Valvuloplasty
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/22—Implements for squeezing-off ulcers or the like on inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; for invasive removal or destruction of calculus using mechanical vibrations; for removing obstructions in blood vessels, not otherwise provided for
    • A61B17/22031—Gripping instruments, e.g. forceps, for removing or smashing calculi
    • A61B2017/22035—Gripping instruments, e.g. forceps, for removing or smashing calculi for retrieving or repositioning foreign objects
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2220/00—Fixations or connections for prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2220/0025—Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements
    • A61F2220/0033—Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements made by longitudinally pushing a protrusion into a complementary-shaped recess, e.g. held by friction fit
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2220/00—Fixations or connections for prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2220/0025—Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements
    • A61F2220/0075—Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements sutured, ligatured or stitched, retained or tied with a rope, string, thread, wire or cable
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2250/0058—Additional features; Implant or prostheses properties not otherwise provided for
    • A61F2250/006—Additional features; Implant or prostheses properties not otherwise provided for modular

Landscapes

  • Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Transplantation (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Surgery (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Prostheses (AREA)

Abstract

Un sistema protésico (70) para reemplazar una válvula cardíaca, comprende un cuerpo de válvula protésico (72) y una estructura de soporte anular (60) dentro de los cuales el cuerpo de válvula protésico puede expandirse hasta que encuentre oposición, el soporte anular se proporciona en dos o más segmentos del anillos (61, 62) que tienen medios de conexión terminales (63) para formar, en la condición de uso del sistema protésico, una estructura anular estable y duradera continua capaz de resistir la oposición ejercida por el cuerpo de válvula protésico, caracterizado porque cada uno de los dos o más segmentos del anillos puede insertarse de manera separada en una cámara cardíaca y puede interconectarse por medio de un sistema de conexión que comprende pasadores (55) y se adapta para acoplarse en agujeros correspondientes (56), en donde la estructura anular formada por la conexión de dos o más segmentos del anillos tiene formas y dimensiones predeterminadas, que coinciden sustancialmente con la anatomía del anillo de la válvula cardíaca, para que sea capaz de rodear la válvula de una manera continua, y en donde cada uno de los dos o más segmentos del anillos es hueco internamente para permitir el paso de al menos un alambre guía (46), los alambres guías emergen de los extremos de cada uno de los dos o más segmentos del anillos, sustancialmente en las posiciones del sistema de conexión.

Description

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Claims (1)

  1. imagen1
ES13812152.0T 2012-11-20 2013-11-19 Sistema protésico para el reemplazo de la válvula cardíaca Active ES2613761T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
ITBO20120636 2012-11-20
IT000636A ITBO20120636A1 (it) 2012-11-20 2012-11-20 Sistema protesico sostitutivo per valvola cardiaca
PCT/IB2013/060250 WO2014080339A1 (en) 2012-11-20 2013-11-19 Prosthetic system for heart valve replacement

Publications (1)

Publication Number Publication Date
ES2613761T3 true ES2613761T3 (es) 2017-05-25

Family

ID=53547733

Family Applications (2)

Application Number Title Priority Date Filing Date
ES16198837T Active ES2939616T3 (es) 2012-11-20 2013-11-19 Sistema protésico para el reemplazo de la válvula cardíaca
ES13812152.0T Active ES2613761T3 (es) 2012-11-20 2013-11-19 Sistema protésico para el reemplazo de la válvula cardíaca

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES16198837T Active ES2939616T3 (es) 2012-11-20 2013-11-19 Sistema protésico para el reemplazo de la válvula cardíaca

Country Status (9)

Country Link
EP (3) EP2922500B1 (es)
JP (2) JP6203859B2 (es)
KR (2) KR102232108B1 (es)
AU (2) AU2013349353B2 (es)
BR (1) BR112015011672B1 (es)
CA (2) CA2922899C (es)
DK (2) DK2922500T3 (es)
ES (2) ES2939616T3 (es)
PL (2) PL3158975T3 (es)

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US8579964B2 (en) 2010-05-05 2013-11-12 Neovasc Inc. Transcatheter mitral valve prosthesis
US9554897B2 (en) 2011-04-28 2017-01-31 Neovasc Tiara Inc. Methods and apparatus for engaging a valve prosthesis with tissue
US9308087B2 (en) 2011-04-28 2016-04-12 Neovasc Tiara Inc. Sequentially deployed transcatheter mitral valve prosthesis
US9345573B2 (en) 2012-05-30 2016-05-24 Neovasc Tiara Inc. Methods and apparatus for loading a prosthesis onto a delivery system
US9572665B2 (en) 2013-04-04 2017-02-21 Neovasc Tiara Inc. Methods and apparatus for delivering a prosthetic valve to a beating heart
KR20150026766A (ko) 2013-08-29 2015-03-11 김준홍 승모판막 서클라지 시술용 카테터 및 이를 이용한 유도방법
DE202016008737U1 (de) 2015-12-15 2019-04-05 Neovasc Tiara Inc. Transseptales Zuführsystem
CN108882981B (zh) 2016-01-29 2021-08-10 内奥瓦斯克迪亚拉公司 用于防止流出阻塞的假体瓣膜
CN109996581B (zh) 2016-11-21 2021-10-15 内奥瓦斯克迪亚拉公司 用于快速收回经导管心脏瓣膜递送系统的方法和系统
AU2018247166B2 (en) * 2017-03-28 2022-06-02 Cardiac Success Ltd. Method of improving cardiac function
CA3073834A1 (en) 2017-08-25 2019-02-28 Neovasc Tiara Inc. Sequentially deployed transcatheter mitral valve prosthesis
KR102167091B1 (ko) * 2018-08-21 2020-10-16 (주) 타우피엔유메디칼 스네어 일체형 심근 전기 신호 감지 카테터
WO2020041495A1 (en) 2018-08-21 2020-02-27 Shifamed, Llc Prosthetic cardiac valve devices, systems, and methods
US10912644B2 (en) 2018-10-05 2021-02-09 Shifamed Holdings, Llc Prosthetic cardiac valve devices, systems, and methods
WO2020082039A1 (en) 2018-10-19 2020-04-23 Shifamed Holdings, Llc Adjustable medical device
WO2020093172A1 (en) 2018-11-08 2020-05-14 Neovasc Tiara Inc. Ventricular deployment of a transcatheter mitral valve prosthesis
WO2020185597A1 (en) 2019-03-08 2020-09-17 Neovasc Tiara Inc. Retrievable prosthesis delivery system
US11602429B2 (en) 2019-04-01 2023-03-14 Neovasc Tiara Inc. Controllably deployable prosthetic valve
EP3952792A4 (en) 2019-04-10 2023-01-04 Neovasc Tiara Inc. HEART VALVE PROSTHESIS WITH NATURAL BLOOD FLOW
EP3972673B1 (en) 2019-05-20 2026-01-28 Neovasc Tiara Inc. Introducer with hemostasis mechanism
KR102207685B1 (ko) * 2019-05-31 2021-01-26 (주) 타우피엔유메디칼 히스 감지 스네어 카테터
CN114144144B (zh) 2019-06-20 2026-01-13 内奥瓦斯克迪亚拉公司 低轮廓假体二尖瓣
US11517425B2 (en) 2019-07-25 2022-12-06 Innovheart S.R.L. Device for implanting a prosthesis for a heart valve and assembly procedure
IT201900015494A1 (it) * 2019-09-03 2021-03-03 Innovheart S R L Dispositivo per la disposizione di fili guida attorno ad una valvola cardiaca
US11684473B2 (en) 2019-07-25 2023-06-27 Innovheart S.R.L. Device for arranging guidewires around a heart valve
AU2020316747B2 (en) * 2019-07-25 2025-08-14 Innovheart S.R.L. Device for arranging guide wires around a heart valve
US20230165679A1 (en) * 2020-04-08 2023-06-01 Shifamed Holdings, Llc Valve delivery system
IT202000012625A1 (it) * 2020-05-27 2021-11-27 Innovheart S R L Dispositivo per afferrare fili guida
JP7835754B2 (ja) 2020-12-04 2026-03-25 シファメド・ホールディングス・エルエルシー 張り出し人工心弁送達デバイスおよびシステム
US12201521B2 (en) 2021-03-22 2025-01-21 Shifamed Holdings, Llc Anchor position verification for prosthetic cardiac valve devices
CN121285358A (zh) * 2023-05-04 2026-01-06 爱德华兹生命科学公司 具有定位构件和稳定构件的假体瓣膜和递送组件

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US7927371B2 (en) * 2005-07-15 2011-04-19 The Cleveland Clinic Foundation Apparatus and method for reducing cardiac valve regurgitation
US8449605B2 (en) 2006-06-28 2013-05-28 Kardium Inc. Method for anchoring a mitral valve
US9125632B2 (en) 2007-10-19 2015-09-08 Guided Delivery Systems, Inc. Systems and methods for cardiac remodeling
US8287591B2 (en) * 2008-09-19 2012-10-16 Edwards Lifesciences Corporation Transformable annuloplasty ring configured to receive a percutaneous prosthetic heart valve implantation
PL3335670T3 (pl) * 2010-03-05 2022-09-05 Edwards Lifesciences Corporation Mechanizmy ustalające do zastawek protetycznych
DE112011102305T5 (de) * 2010-07-09 2013-05-16 Highlife Sas Transkatheter-Atrioventrikular-Klappenprothese
EP2600799B1 (en) * 2010-08-04 2017-05-17 ValCare, Inc. Percutaneous transcatheter repair of heart valves
IT1402571B1 (it) * 2010-11-12 2013-09-13 Ht Consultant Di Giovanni Righini Sistema protesico per valvola cardio-vascolare con struttura di ancoraggio separata
WO2012087842A1 (en) * 2010-12-23 2012-06-28 The Foundry, Llc System for mitral valve repair and replacement
US9039713B2 (en) * 2011-05-13 2015-05-26 Merit Medical Systems, Inc. Releasably attached snare loop retrieval device and method of using the same
US9011531B2 (en) * 2012-02-13 2015-04-21 Mitraspan, Inc. Method and apparatus for repairing a mitral valve
WO2013131925A1 (en) * 2012-03-06 2013-09-12 Highlife Sas Treatment catheter member with encircling function

Also Published As

Publication number Publication date
CA2922899C (en) 2021-12-28
BR112015011672B1 (pt) 2021-08-31
KR20150091336A (ko) 2015-08-10
EP2922500A1 (en) 2015-09-30
DK2922500T3 (en) 2017-02-06
AU2013349353B2 (en) 2017-11-09
ES2939616T3 (es) 2023-04-25
JP6434589B2 (ja) 2018-12-05
JP2017221747A (ja) 2017-12-21
KR102232108B1 (ko) 2021-03-25
EP3158975A1 (en) 2017-04-26
PL3158975T3 (pl) 2023-05-02
EP2922500B1 (en) 2016-11-16
KR20200134337A (ko) 2020-12-01
AU2018200730B2 (en) 2019-08-15
EP3158975B1 (en) 2023-01-04
CA2922899A1 (en) 2014-05-30
AU2018200730A1 (en) 2018-03-08
PL2922500T3 (pl) 2017-05-31
EP4147676A1 (en) 2023-03-15
CA3112256C (en) 2023-09-26
BR112015011672A2 (pt) 2017-07-11
DK3158975T3 (da) 2023-03-13
CA3112256A1 (en) 2014-05-30
KR102280752B1 (ko) 2021-07-22
AU2013349353A1 (en) 2015-07-09
JP6203859B2 (ja) 2017-09-27
JP2016503320A (ja) 2016-02-04

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