ES264077A1 - Un procedimiento de obtenciën de derivados de piperidina y pirrolidina y de sus sales acidas de adiciën - Google Patents
Un procedimiento de obtenciën de derivados de piperidina y pirrolidina y de sus sales acidas de adiciënInfo
- Publication number
- ES264077A1 ES264077A1 ES0264077A ES264077A ES264077A1 ES 264077 A1 ES264077 A1 ES 264077A1 ES 0264077 A ES0264077 A ES 0264077A ES 264077 A ES264077 A ES 264077A ES 264077 A1 ES264077 A1 ES 264077A1
- Authority
- ES
- Spain
- Prior art keywords
- ethers
- salts
- procedure
- chlorine
- carbon atoms
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000003839 salts Chemical class 0.000 title abstract 5
- RWRDLPDLKQPQOW-UHFFFAOYSA-N Pyrrolidine Chemical class C1CCNC1 RWRDLPDLKQPQOW-UHFFFAOYSA-N 0.000 title abstract 4
- 239000002253 acid Substances 0.000 title abstract 2
- NQRYJNQNLNOLGT-UHFFFAOYSA-N Piperidine Chemical compound C1CCNCC1 NQRYJNQNLNOLGT-UHFFFAOYSA-N 0.000 title 2
- -1 with hydrochloric Chemical class 0.000 abstract 3
- WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical group [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000004432 carbon atom Chemical group C* 0.000 abstract 2
- 229910052801 chlorine Inorganic materials 0.000 abstract 2
- 239000000460 chlorine Chemical group 0.000 abstract 2
- 150000002170 ethers Chemical class 0.000 abstract 2
- 150000003053 piperidines Chemical class 0.000 abstract 2
- KZBUYRJDOAKODT-UHFFFAOYSA-N Chlorine Chemical group ClCl KZBUYRJDOAKODT-UHFFFAOYSA-N 0.000 abstract 1
- PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical group FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 abstract 1
- PVQATPQSBYNMGE-UHFFFAOYSA-N [benzhydryloxy(phenyl)methyl]benzene Chemical class C=1C=CC=CC=1C(C=1C=CC=CC=1)OC(C=1C=CC=CC=1)C1=CC=CC=C1 PVQATPQSBYNMGE-UHFFFAOYSA-N 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 230000001387 anti-histamine Effects 0.000 abstract 1
- 229940125715 antihistaminic agent Drugs 0.000 abstract 1
- 239000000739 antihistaminic agent Substances 0.000 abstract 1
- WPYMKLBDIGXBTP-UHFFFAOYSA-N benzoic acid group Chemical group C(C1=CC=CC=C1)(=O)O WPYMKLBDIGXBTP-UHFFFAOYSA-N 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 125000001309 chloro group Chemical group Cl* 0.000 abstract 1
- 229910052731 fluorine Inorganic materials 0.000 abstract 1
- 239000011737 fluorine Chemical group 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- XTEGVFVZDVNBPF-UHFFFAOYSA-N naphthalene-1,5-disulfonic acid Chemical class C1=CC=C2C(S(=O)(=O)O)=CC=CC2=C1S(O)(=O)=O XTEGVFVZDVNBPF-UHFFFAOYSA-N 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
- C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrrole Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH53760A CH382164A (de) | 1960-01-19 | 1960-01-19 | Verfahren zur Herstellung von neuen Äthern |
| CH880760A CH389608A (de) | 1960-01-19 | 1960-08-03 | Verfahren zur Herstellung von neuen Äthern |
| CH1089760 | 1960-09-27 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES264077A1 true ES264077A1 (es) | 1961-07-16 |
Family
ID=27172192
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES0264077A Expired ES264077A1 (es) | 1960-01-19 | 1961-01-18 | Un procedimiento de obtenciën de derivados de piperidina y pirrolidina y de sus sales acidas de adiciën |
Country Status (8)
| Country | Link |
|---|---|
| BR (1) | BR6125965D0 (fr) |
| CH (1) | CH389608A (fr) |
| CY (1) | CY379A (fr) |
| DE (1) | DE1228262B (fr) |
| ES (1) | ES264077A1 (fr) |
| FR (1) | FR1279691A (fr) |
| GB (1) | GB942152A (fr) |
| OA (1) | OA00698A (fr) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1307255A (en) * | 1970-09-12 | 1973-02-14 | Pfizer Ltd | Substituted basic benzhydryl ethers |
| JPS5223068A (en) * | 1975-08-13 | 1977-02-21 | Nippon Kayaku Co Ltd | Preparation of optically active 1-methyl -2-(2'-(alpha-methyl-p-chlorobenz hydryloxy) ethtyl) pyrrolidine fumarates |
| US4835164A (en) * | 1987-02-20 | 1989-05-30 | A. H. Robins Company, Incorporated | Aryloxymethyl derivatives of nitrogenous heterocyclic methanols and ethers thereof |
| SI1583542T1 (sl) | 2003-01-14 | 2008-12-31 | Gilead Sciences Inc | Sestavki in postopki za kombinacijsko antivirusnoterapijo |
| TWI375560B (en) | 2005-06-13 | 2012-11-01 | Gilead Sciences Inc | Composition comprising dry granulated emtricitabine and tenofovir df and method for making the same |
| TWI471145B (zh) | 2005-06-13 | 2015-02-01 | Bristol Myers Squibb & Gilead Sciences Llc | 單一式藥學劑量型 |
| CN107011228B (zh) * | 2017-05-24 | 2019-08-09 | 浙江诚意药业股份有限公司 | 一种富马酸氯马斯汀的制备方法 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE934890C (de) * | 1951-10-07 | 1955-11-10 | Chem Fab Promonta Ges Mit Besc | Verfahren zur Herstellung von basischen Benzhydrylaethern |
-
1960
- 1960-08-03 CH CH880760A patent/CH389608A/de unknown
- 1960-12-14 GB GB43068/60A patent/GB942152A/en not_active Expired
-
1961
- 1961-01-17 FR FR849932A patent/FR1279691A/fr not_active Expired
- 1961-01-18 ES ES0264077A patent/ES264077A1/es not_active Expired
- 1961-01-18 DE DES72107A patent/DE1228262B/de active Pending
- 1961-01-18 BR BR125965/61A patent/BR6125965D0/pt unknown
-
1964
- 1964-12-08 OA OA50776A patent/OA00698A/fr unknown
-
1967
- 1967-03-04 CY CY37967A patent/CY379A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| BR6125965D0 (pt) | 1973-06-28 |
| DE1228262B (de) | 1966-11-10 |
| CY379A (en) | 1967-03-04 |
| FR1279691A (fr) | 1961-12-22 |
| CH389608A (de) | 1965-03-31 |
| GB942152A (en) | 1963-11-20 |
| OA00698A (fr) | 1967-07-15 |
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