ES267171A1 - Procedimiento de preparaciën de derivados de 5-halëgeno-alfa-beta-benzo-piridina - Google Patents

Procedimiento de preparaciën de derivados de 5-halëgeno-alfa-beta-benzo-piridina

Info

Publication number: ES267171A1
Authority: ES; Spain
Prior art keywords: quinolines; quinaldines; alkyl; hydrogen; prepared
Prior art date: 1960-05-06
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired

Application number

ES0267171A

Other languages

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Sandoz AG

Original Assignee

Sandoz AG

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1960-05-06

Filing date

1961-05-05

Publication date

1961-11-01

1960-05-06 Priority claimed from CH518160A external-priority patent/CH393326A/de

1960-05-20 Priority claimed from CH578460A external-priority patent/CH393327A/de

1961-05-05 Application filed by Sandoz AG filed Critical Sandoz AG

1961-11-01 Publication of ES267171A1 publication Critical patent/ES267171A1/es

Status Expired legal-status Critical Current

Links

229940111121 antirheumatic drug quinolines Drugs 0.000 title abstract 3
150000003248 quinolines Chemical class 0.000 title abstract 2
JUJWROOIHBZHMG-UHFFFAOYSA-N Pyridine Chemical compound C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 abstract 2
125000000217 alkyl group Chemical group 0.000 abstract 2
229910052739 hydrogen Inorganic materials 0.000 abstract 2
239000001257 hydrogen Substances 0.000 abstract 2
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
SMUQFGGVLNAIOZ-UHFFFAOYSA-N quinaldine Chemical class C1=CC=CC2=NC(C)=CC=C21 SMUQFGGVLNAIOZ-UHFFFAOYSA-N 0.000 abstract 2
LLJNHRLWARQRIH-UHFFFAOYSA-N (2-methylquinolin-8-yl) 4-chlorobenzoate Chemical compound C12=NC(C)=CC=C2C=CC=C1OC(=O)C1=CC=C(Cl)C=C1 LLJNHRLWARQRIH-UHFFFAOYSA-N 0.000 abstract 1
MGWVENWANVOZBU-UHFFFAOYSA-N (2-methylquinolin-8-yl) benzoate Chemical compound C12=NC(C)=CC=C2C=CC=C1OC(=O)C1=CC=CC=C1 MGWVENWANVOZBU-UHFFFAOYSA-N 0.000 abstract 1
NBYLBWHHTUWMER-UHFFFAOYSA-N 2-Methylquinolin-8-ol Chemical compound C1=CC=C(O)C2=NC(C)=CC=C21 NBYLBWHHTUWMER-UHFFFAOYSA-N 0.000 abstract 1
DGDDNENNGRGKDE-UHFFFAOYSA-N 2-methyl-8-[(4-nitrophenyl)methoxy]quinoline Chemical compound C12=NC(C)=CC=C2C=CC=C1OCC1=CC=C([N+]([O-])=O)C=C1 DGDDNENNGRGKDE-UHFFFAOYSA-N 0.000 abstract 1
WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical group [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 abstract 1
239000002253 acid Substances 0.000 abstract 1
150000008064 anhydrides Chemical class 0.000 abstract 1
PASDCCFISLVPSO-UHFFFAOYSA-N benzoyl chloride Chemical compound ClC(=O)C1=CC=CC=C1 PASDCCFISLVPSO-UHFFFAOYSA-N 0.000 abstract 1
GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Chemical group BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 abstract 1
229910052794 bromium Chemical group 0.000 abstract 1
125000004432 carbon atom Chemical group C* 0.000 abstract 1
229910052801 chlorine Inorganic materials 0.000 abstract 1
239000000460 chlorine Substances 0.000 abstract 1
125000001309 chloro group Chemical group Cl* 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
230000032050 esterification Effects 0.000 abstract 1
238000005886 esterification reaction Methods 0.000 abstract 1
230000002070 germicidal effect Effects 0.000 abstract 1
150000004820 halides Chemical class 0.000 abstract 1
229910052736 halogen Inorganic materials 0.000 abstract 1
230000026030 halogenation Effects 0.000 abstract 1
238000005658 halogenation reaction Methods 0.000 abstract 1
150000002367 halogens Chemical class 0.000 abstract 1
125000005059 halophenyl group Chemical group 0.000 abstract 1
125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
239000000203 mixture Substances 0.000 abstract 1
125000006501 nitrophenyl group Chemical group 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
UMJSCPRVCHMLSP-UHFFFAOYSA-N pyridine Natural products COC1=CC=CN=C1 UMJSCPRVCHMLSP-UHFFFAOYSA-N 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/24—Oxygen atoms attached in position 8
- C07D215/26—Alcohols; Ethers thereof
- C07D215/32—Esters

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

ES0267171A 1960-05-06 1961-05-05 Procedimiento de preparaciën de derivados de 5-halëgeno-alfa-beta-benzo-piridina Expired ES267171A1 (es)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
CH518160A CH393326A (de)	1960-05-06	1960-05-06	Verfahren zur Herstellung von neuen Estern von 5-Halogen-8-oxychinaldinen
CH578460A CH393327A (de)	1960-05-20	1960-05-20	Verfahren zur Herstellung von neuen Estern von 5-Halogen-8-oxychinolinen

Publications (1)

Publication Number	Publication Date
ES267171A1 true ES267171A1 (es)	1961-11-01

Family

ID=25697149

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ES0267171A Expired ES267171A1 (es)	1960-05-06	1961-05-05	Procedimiento de preparaciën de derivados de 5-halëgeno-alfa-beta-benzo-piridina

Country Status (2)

Country	Link
ES (1)	ES267171A1 (es)
GB (1)	GB977334A (es)

1961
- 1961-04-27 GB GB1527961A patent/GB977334A/en not_active Expired
- 1961-05-05 ES ES0267171A patent/ES267171A1/es not_active Expired

Also Published As

Publication number	Publication date
GB977334A (en)	1964-12-09

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