ES2913659T3 - Cuerpo separador - Google Patents
Cuerpo separador Download PDFInfo
- Publication number
- ES2913659T3 ES2913659T3 ES18721020T ES18721020T ES2913659T3 ES 2913659 T3 ES2913659 T3 ES 2913659T3 ES 18721020 T ES18721020 T ES 18721020T ES 18721020 T ES18721020 T ES 18721020T ES 2913659 T3 ES2913659 T3 ES 2913659T3
- Authority
- ES
- Spain
- Prior art keywords
- float
- density
- fingers
- phase
- shaped
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 238000007789 sealing Methods 0.000 claims abstract description 28
- 210000004369 blood Anatomy 0.000 claims abstract description 25
- 239000008280 blood Substances 0.000 claims abstract description 25
- 239000007788 liquid Substances 0.000 claims abstract description 23
- 210000002966 serum Anatomy 0.000 claims abstract description 11
- 230000008719 thickening Effects 0.000 claims abstract description 7
- 238000007667 floating Methods 0.000 claims abstract description 4
- 239000013013 elastic material Substances 0.000 claims abstract 2
- 125000006850 spacer group Chemical group 0.000 claims description 20
- 239000000853 adhesive Substances 0.000 claims description 11
- 230000001070 adhesive effect Effects 0.000 claims description 11
- 239000000463 material Substances 0.000 claims description 5
- VYZAMTAEIAYCRO-UHFFFAOYSA-N Chromium Chemical compound [Cr] VYZAMTAEIAYCRO-UHFFFAOYSA-N 0.000 claims description 3
- 229910052804 chromium Inorganic materials 0.000 claims description 3
- 239000011651 chromium Substances 0.000 claims description 3
- 230000003068 static effect Effects 0.000 claims description 2
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 abstract description 4
- 229910052801 chlorine Inorganic materials 0.000 abstract description 4
- 239000000460 chlorine Substances 0.000 abstract description 4
- 239000012071 phase Substances 0.000 description 36
- 230000005484 gravity Effects 0.000 description 6
- 238000005119 centrifugation Methods 0.000 description 4
- 230000000694 effects Effects 0.000 description 4
- 239000012530 fluid Substances 0.000 description 3
- 238000002347 injection Methods 0.000 description 3
- 239000007924 injection Substances 0.000 description 3
- 230000005012 migration Effects 0.000 description 3
- 238000013508 migration Methods 0.000 description 3
- 238000000926 separation method Methods 0.000 description 3
- 230000009471 action Effects 0.000 description 2
- 230000017531 blood circulation Effects 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 description 1
- 230000035508 accumulation Effects 0.000 description 1
- 238000009825 accumulation Methods 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- 230000001419 dependent effect Effects 0.000 description 1
- 238000001746 injection moulding Methods 0.000 description 1
- 239000007791 liquid phase Substances 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 239000012858 resilient material Substances 0.000 description 1
- 238000009827 uniform distribution Methods 0.000 description 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5021—Test tubes specially adapted for centrifugation purposes
- B01L3/50215—Test tubes specially adapted for centrifugation purposes using a float to separate phases
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/15—Devices for taking samples of blood
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D17/00—Separation of liquids, not provided for elsewhere, e.g. by thermal diffusion
- B01D17/12—Auxiliary equipment particularly adapted for use with liquid-separating apparatus, e.g. control circuits
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/15—Devices for taking samples of blood
- A61B5/150007—Details
- A61B5/150015—Source of blood
- A61B5/15003—Source of blood for venous or arterial blood
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/15—Devices for taking samples of blood
- A61B5/150007—Details
- A61B5/150755—Blood sample preparation for further analysis, e.g. by separating blood components or by mixing
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D21/00—Separation of suspended solid particles from liquids by sedimentation
- B01D21/26—Separation of sediment aided by centrifugal force or centripetal force
- B01D21/262—Separation of sediment aided by centrifugal force or centripetal force by using a centrifuge
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D21/00—Separation of suspended solid particles from liquids by sedimentation
- B01D21/30—Control equipment
- B01D21/307—Passive control mechanisms without external energy, e.g. using a float
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D2221/00—Applications of separation devices
- B01D2221/10—Separation devices for use in medical, pharmaceutical or laboratory applications, e.g. separating amalgam from dental treatment residues
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/06—Fluid handling related problems
- B01L2200/0689—Sealing
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/04—Closures and closing means
- B01L2300/041—Connecting closures to device or container
- B01L2300/042—Caps; Plugs
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
- B01L2400/0409—Moving fluids with specific forces or mechanical means specific forces centrifugal forces
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
- G01N33/487—Physical analysis of biological material of liquid biological material
- G01N33/49—Blood
- G01N33/491—Blood by separating the blood components
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Analytical Chemistry (AREA)
- Clinical Laboratory Science (AREA)
- Biophysics (AREA)
- Pathology (AREA)
- Molecular Biology (AREA)
- Surgery (AREA)
- Food Science & Technology (AREA)
- Medical Informatics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Thermal Sciences (AREA)
- Ecology (AREA)
- Urology & Nephrology (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Centrifugal Separators (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- External Artificial Organs (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102017108937.3A DE102017108937B4 (de) | 2017-04-26 | 2017-04-26 | Trennkörper |
| PCT/EP2018/060602 WO2018197565A1 (de) | 2017-04-26 | 2018-04-25 | Trennkörper |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2913659T3 true ES2913659T3 (es) | 2022-06-03 |
Family
ID=62089747
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES18721020T Active ES2913659T3 (es) | 2017-04-26 | 2018-04-25 | Cuerpo separador |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US11241685B2 (pl) |
| EP (1) | EP3614923B1 (pl) |
| CN (1) | CN110520046B (pl) |
| DE (1) | DE102017108937B4 (pl) |
| DK (1) | DK3614923T3 (pl) |
| ES (1) | ES2913659T3 (pl) |
| PL (1) | PL3614923T3 (pl) |
| RU (1) | RU2742809C1 (pl) |
| WO (1) | WO2018197565A1 (pl) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11478787B2 (en) | 2018-07-09 | 2022-10-25 | Hanuman Pelican, Inc. | Apparatus and methods for separating blood components |
| CA3099911A1 (en) | 2018-07-09 | 2020-01-16 | Hanuman Pelican, Inc. | Apparatus and methods for processing blood |
| US12440835B2 (en) | 2019-01-21 | 2025-10-14 | Vias Partners, Llc | Methods, systems and apparatus for separating components of a biological sample |
| US11559613B2 (en) | 2019-02-06 | 2023-01-24 | Hanuman Pelican, Inc. | Apparatus and methods for concentrating platelet-rich plasma |
| KR20220091580A (ko) | 2019-10-31 | 2022-06-30 | 이클립스 메드코프 엘엘씨 | 샘플의 구성요소들을 분리하기 위한 시스템, 방법 및 장치 |
Family Cites Families (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3887464A (en) | 1974-02-27 | 1975-06-03 | Becton Dickinson Co | Serum/plasma separator with centrifugal valve seal |
| EP0017127B1 (en) | 1979-03-23 | 1985-01-23 | Terumo Corporation | A method for separating blood and a barrier device therefor |
| US4443345A (en) * | 1982-06-28 | 1984-04-17 | Wells John R | Serum preparator |
| US4843869A (en) | 1988-03-21 | 1989-07-04 | Levine Robert A | Method for measuring hemoglobin |
| US5269927A (en) * | 1991-05-29 | 1993-12-14 | Sherwood Medical Company | Separation device for use in blood collection tubes |
| US5575778A (en) * | 1994-09-21 | 1996-11-19 | B. Braun Melsungen Ag | Blood-taking device |
| WO1996024058A1 (en) * | 1995-01-30 | 1996-08-08 | Niigata Engineering Co., Ltd. | Component separation member and component separator equipped with said member |
| US5632905A (en) * | 1995-08-07 | 1997-05-27 | Haynes; John L. | Method and apparatus for separating formed and unformed components |
| JPH09222427A (ja) * | 1995-12-11 | 1997-08-26 | Sekisui Chem Co Ltd | 血液検査容器 |
| US20020156439A1 (en) * | 1997-09-12 | 2002-10-24 | Michael J. Iskra | Collection container assembly |
| US6479298B1 (en) * | 1998-12-05 | 2002-11-12 | Becton, Dickinson And Company | Device and method for separating components of a fluid sample |
| US20020132367A1 (en) | 1998-12-05 | 2002-09-19 | Miller Henry F. | Device and method for separating components of a fluid sample |
| US6406671B1 (en) * | 1998-12-05 | 2002-06-18 | Becton, Dickinson And Company | Device and method for separating components of a fluid sample |
| US6280400B1 (en) | 1998-12-05 | 2001-08-28 | Becton Dickinson And Company | Device and method for separating component of a liquid sample |
| US6537503B1 (en) * | 1999-12-03 | 2003-03-25 | Becton Dickinson And Company | Device and method for separating components of a fluid sample |
| US6803022B2 (en) | 1999-12-06 | 2004-10-12 | Becton, Dickinson And Company | Device and method for separating components of a fluid sample |
| US6409528B1 (en) | 1999-12-06 | 2002-06-25 | Becton, Dickinson And Company | Device and method for collecting, preparation and stabilizing a sample |
| AT500247B1 (de) * | 2001-03-30 | 2007-06-15 | Greiner Bio One Gmbh | Aufnahmeeinrichtung, insbesondere für körperflüssigkeiten, mit einer trennvorrichtung sowie trennvorrichtung hierzu |
| US7736593B2 (en) * | 2003-08-05 | 2010-06-15 | Becton, Dickinson And Company | Device and methods for collection of biological fluid sample and treatment of selected components |
| CN101952006A (zh) * | 2007-12-07 | 2011-01-19 | 丰收技术股份有限公司 | 用于分离血液成分的浮动盘 |
| US9333445B2 (en) * | 2008-07-21 | 2016-05-10 | Becton, Dickinson And Company | Density phase separation device |
| KR101609226B1 (ko) * | 2008-12-04 | 2016-04-06 | 써모제너시스 코포레이션 | 생물학적 유체의 성분들을 분리 및 격리시키기 위한 장치 및 방법 |
| EP2921233B1 (en) * | 2009-05-15 | 2019-10-16 | Becton, Dickinson and Company | Density phase separation device |
| US20120223027A1 (en) * | 2011-03-02 | 2012-09-06 | Jonathan Lundt | Tube and float systems |
| EP2666533B1 (en) * | 2012-05-24 | 2018-11-14 | Grupo Guascor, S.L. Unipersonal | Reducing tar balls in gasification system |
| CN105074459A (zh) | 2013-02-01 | 2015-11-18 | 莱尔赛特公司 | 管和浮体系统以及使用所述系统的方法 |
| US9694359B2 (en) * | 2014-11-13 | 2017-07-04 | Becton, Dickinson And Company | Mechanical separator for a biological fluid |
| JP2018088831A (ja) * | 2015-04-03 | 2018-06-14 | 株式会社カネカ | 細胞分離デバイス及び細胞分離システム |
-
2017
- 2017-04-26 DE DE102017108937.3A patent/DE102017108937B4/de active Active
-
2018
- 2018-04-25 CN CN201880027203.6A patent/CN110520046B/zh active Active
- 2018-04-25 ES ES18721020T patent/ES2913659T3/es active Active
- 2018-04-25 RU RU2019137960A patent/RU2742809C1/ru active
- 2018-04-25 EP EP18721020.8A patent/EP3614923B1/de active Active
- 2018-04-25 DK DK18721020.8T patent/DK3614923T3/da active
- 2018-04-25 PL PL18721020T patent/PL3614923T3/pl unknown
- 2018-04-25 US US16/608,776 patent/US11241685B2/en active Active
- 2018-04-25 WO PCT/EP2018/060602 patent/WO2018197565A1/de not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| DE102017108937A1 (de) | 2018-10-31 |
| RU2742809C1 (ru) | 2021-02-10 |
| BR112019018092A2 (pt) | 2020-03-31 |
| CN110520046A (zh) | 2019-11-29 |
| US11241685B2 (en) | 2022-02-08 |
| CN110520046B (zh) | 2022-08-02 |
| EP3614923B1 (de) | 2022-03-30 |
| DE102017108937B4 (de) | 2018-12-06 |
| WO2018197565A1 (de) | 2018-11-01 |
| EP3614923A1 (de) | 2020-03-04 |
| DK3614923T3 (da) | 2022-05-30 |
| PL3614923T3 (pl) | 2022-06-20 |
| US20200197929A1 (en) | 2020-06-25 |
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