ES291778U - Aparato para la deteccion y determinacion de por lo menos un ligando en una muestra sospechosa de contener dicho ligando - Google Patents
Aparato para la deteccion y determinacion de por lo menos un ligando en una muestra sospechosa de contener dicho ligandoInfo
- Publication number
- ES291778U ES291778U ES1986291778U ES291778U ES291778U ES 291778 U ES291778 U ES 291778U ES 1986291778 U ES1986291778 U ES 1986291778U ES 291778 U ES291778 U ES 291778U ES 291778 U ES291778 U ES 291778U
- Authority
- ES
- Spain
- Prior art keywords
- chamber
- ligand
- labeled component
- binding partner
- complex
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000003018 immunoassay Methods 0.000 title 1
- 239000003446 ligand Substances 0.000 abstract 8
- 150000001875 compounds Chemical class 0.000 abstract 3
- 239000000463 material Substances 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 238000000926 separation method Methods 0.000 abstract 2
- 239000007795 chemical reaction product Substances 0.000 abstract 1
- 238000001514 detection method Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000011541 reaction mixture Substances 0.000 abstract 1
- 239000000725 suspension Substances 0.000 abstract 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
- G01N33/537—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody
Landscapes
- Health & Medical Sciences (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Hematology (AREA)
- Engineering & Computer Science (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Urology & Nephrology (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Cell Biology (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Clinical Laboratory Science (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Steroid Compounds (AREA)
Abstract
Aparato para la detección y determinación de por lo menos un ligando en una muestra sospechosa de contener dicho ligando, cuyo aparato comprende: una primera vasija con una primera cámara para recibir una muestra sospechosa de contener el ligando, la primera cámara contiene una mezcla de un copartícipe de unión para dicho ligando y un componente marcado seleccionado entre el grupo formado por un copartícipe de unión, un compuesto que puede unirse al copartícipe de unión, un compuesto que puede unirse al producto de reacción del ligando y el copartícipe de unión y un compuesto que puede unirse al ligando; un elemento separador dispuesto en la primera vasija para permitir el paso a su través del componente marcado libre de un tamaño relativamente pequeño mientras que impide el paso de un complejo formado a partir del ligando, el copartícipe de unión y el componente marcado, de un tamaño relativamente mayor que el componente marcado libre cuando se establece una diferencia de presiones a través de dicho elemento separador; una segunda vasija con una segunda cámara en la que reina una presión reducida; una tapa perforable que cierra la segunda cámara de la segunda vasija; un orificio de salida en la primera vasija; un cubo de aguja conectado al orificio de salida de la primera vasija y una cánula de aguja conectada al cubo de aguja, cuya cánula de aguja es capaz de perforar la tapa superior de la segunda vasija para exponer el elemento separador a la presión reducida de la segunda vasija y establecer una diferencia de presiones a través del elemento separador para separar el componente marcado libre del complejo, cuyo componente marcado libre fluye a través de la cánula de aguja y es recogido en la segunda cámara de la segunda vasija.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/544,177 US4786471A (en) | 1983-10-21 | 1983-10-21 | Heterogeneous immunoassay method and assembly |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES291778U true ES291778U (es) | 1986-05-16 |
| ES291778Y ES291778Y (es) | 1987-01-16 |
Family
ID=24171063
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES536947A Expired ES8606661A1 (es) | 1983-10-21 | 1984-10-19 | Un metodo para la deteccion y determinacion de por lo menos un ligando en una muestra sospechosa de contener dicho ligando |
| ES1986291778U Expired ES291778Y (es) | 1983-10-21 | 1986-01-20 | Aparato para la deteccion y determinacion de por lo menos un ligando en una muestra sospechosa de contener dicho ligando |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES536947A Expired ES8606661A1 (es) | 1983-10-21 | 1984-10-19 | Un metodo para la deteccion y determinacion de por lo menos un ligando en una muestra sospechosa de contener dicho ligando |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US4786471A (es) |
| EP (1) | EP0141547B1 (es) |
| JP (1) | JPS60115865A (es) |
| AT (1) | ATE49300T1 (es) |
| CA (1) | CA1229300A (es) |
| DE (1) | DE3480951D1 (es) |
| ES (2) | ES8606661A1 (es) |
Families Citing this family (41)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| USRE34405E (en) * | 1983-08-01 | 1993-10-12 | Abbott Laboratories | Determination of analytes in particle-containing medium |
| SE460564B (sv) * | 1985-03-25 | 1989-10-23 | Euro Fassel Ab | Testsats och foerfarande foer immunanalys med prefabricerade komplex av maerkt antikropp och analytspecifik antikropp |
| US4623461A (en) * | 1985-05-31 | 1986-11-18 | Murex Corporation | Transverse flow diagnostic device |
| IL78854A (en) * | 1985-05-31 | 1991-11-21 | Murex Corp | Biological fluid diagnostic device |
| JPS62194458A (ja) * | 1986-02-21 | 1987-08-26 | Arinobu Fujimura | 免疫学的測定法とその測定法に用いる免疫学的測定器具 |
| DE3608883C1 (de) * | 1986-03-17 | 1987-08-13 | Armin Dipl-Chem Dr Rer N Gilak | Chromatographische Saeule fuer immunologische Untersuchungsverfahren |
| US4812293A (en) * | 1986-06-30 | 1989-03-14 | Becton, Dickinson And Company | Vacuum actuated assay device and method of using same |
| JPS6319559A (ja) * | 1986-07-11 | 1988-01-27 | Fuji Photo Film Co Ltd | 免疫分析方法 |
| JPS6321559A (ja) * | 1986-07-16 | 1988-01-29 | Matsushita Electric Ind Co Ltd | ハプテンの酵素免疫測定法 |
| US4797260A (en) * | 1987-01-27 | 1989-01-10 | V-Tech, Inc. | Antibody testing system |
| JPS63238462A (ja) * | 1987-03-27 | 1988-10-04 | Eiken Kagaku Kk | 特異結合分析法 |
| US4857453A (en) * | 1987-04-07 | 1989-08-15 | Syntex (U.S.A.) Inc. | Immunoassay device |
| US5128104A (en) * | 1987-04-27 | 1992-07-07 | Murphy Harold R | Cuvette for automated testing machine |
| US4873126A (en) * | 1988-08-15 | 1989-10-10 | Becton, Dickinson And Company | System and process for spotting reagents on porous supports |
| US5429803A (en) | 1991-04-18 | 1995-07-04 | Lamina, Inc. | Liquid specimen container and attachable testing modules |
| JP2515391B2 (ja) * | 1989-03-02 | 1996-07-10 | 日本電子株式会社 | 自動免疫測定装置 |
| JP2515392B2 (ja) * | 1989-03-02 | 1996-07-10 | 日本電子株式会社 | 自動免疫測定装置 |
| IT1229165B (it) * | 1989-04-07 | 1991-07-22 | Leopardi Francesco Paoletti Se | Dispositivo per chiudere provette sotto vuoto per il prelievo di sangue. |
| DE3941098C2 (de) * | 1989-12-13 | 1994-02-03 | Dornier Gmbh | Vorrichtung zur Herstellung von Kristallen |
| DE3941099A1 (de) * | 1989-12-13 | 1991-06-20 | Dornier Gmbh | Handhabung von fluessigkeiten unter schwerelosigkeit |
| DK200890D0 (da) * | 1990-08-22 | 1990-08-22 | Ulf Nonboe | Metode til bestemmelse af lugtende svinekoed |
| SE503729C2 (sv) * | 1991-03-11 | 1996-08-12 | Mats Malmquist | Extraktionssystem |
| USRE39457E1 (en) * | 1991-04-18 | 2007-01-02 | Lamina, Inc. | Liquid specimen container and attachable testing modules |
| US5286453A (en) * | 1992-04-02 | 1994-02-15 | Pope Carolyn M | Device for dispensing a biological fluid from a sealed vacuum tube |
| US5364591A (en) * | 1992-06-01 | 1994-11-15 | Eastman Kodak Company | Device for moving a target-bearing solid through a liquid for detection while being contained |
| CA2105698A1 (en) * | 1992-09-16 | 1994-03-17 | Jozsef Hepp | Label trapping assay-nonseparation binding assay method |
| US5401467A (en) * | 1993-07-21 | 1995-03-28 | Eastman Kodak Company | Whole blood metering cup |
| JPH10504834A (ja) * | 1994-08-29 | 1998-05-12 | アクゾ・ノベル・エヌ・ベー | 核酸などの生物材料の単離に使用する装置 |
| PT924991E (pt) | 1996-07-02 | 2002-02-28 | Bbi Bioseq Inc | Ligacao mediada por pressao de complexos biomoleculares |
| WO2003019131A2 (de) * | 2001-08-29 | 2003-03-06 | Hexal Pharma Gmbh | Verfahren und vorrichtung zur vorbereitung einer biologischen urprobe für die bestimmung zumindest einer darin enthaltenen komponente |
| US7090803B1 (en) * | 2003-10-28 | 2006-08-15 | American Bio Medica Corporation | Lateral flow immunoassay device |
| DE102006002258B4 (de) * | 2006-01-17 | 2008-08-21 | Siemens Ag | Modul zur Aufbereitung einer biologischen Probe, Biochip-Satz und Verwendung des Moduls |
| US20080017577A1 (en) * | 2006-07-21 | 2008-01-24 | Becton, Dickinson And Company | Membrane-based Double-layer Tube for Sample Collections |
| US20100261157A1 (en) * | 2007-12-11 | 2010-10-14 | Siemens Healthcare Diagnostics Inc. | Device and Method for Processing a Sample Contained in a Swab for Diagnostic Analysis |
| JP2012159337A (ja) * | 2011-01-31 | 2012-08-23 | Sony Corp | サンプル液供給治具、サンプル液供給治具セット及びマイクロチップセット |
| CA2854768C (en) * | 2011-11-10 | 2021-08-17 | David E. Jones | Loading vials |
| WO2015070712A1 (en) * | 2013-11-14 | 2015-05-21 | Abon Biopharm (Hangzhou) Co., Ltd. | A device and method for using the device |
| HK1243491A1 (zh) * | 2015-01-22 | 2018-07-13 | 日本电气方案创新株式会社 | 靶分析工具和靶分析方法 |
| WO2019178247A1 (en) * | 2018-03-15 | 2019-09-19 | Biolum Sciences Llc | Sensor devices and systems for monitoring markers in breath |
| WO2020262991A1 (ko) * | 2019-06-25 | 2020-12-30 | (주) 메디젠휴먼케어 | 액체 생검용 수집장치 |
| WO2024234288A1 (zh) * | 2023-05-16 | 2024-11-21 | 北京青元开物技术有限公司 | 一种全封闭式检测装置、系统及应用 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2028822A1 (en) * | 1970-06-11 | 1971-12-16 | Keller H | Biochemical determinations - in completely equipped test - containers including all necessary reagents and solvents |
| US3706305A (en) * | 1971-03-03 | 1972-12-19 | Harold J Berger | Combination blood sampling vacuum syringe centrifuge container and specimen cup |
| US4146365A (en) * | 1977-11-07 | 1979-03-27 | Litton Bionetics, Inc. | Affinity detection apparatus |
| US4301139A (en) * | 1979-06-21 | 1981-11-17 | Ames-Yissum Ltd. | Multilayer column chromatography specific binding assay method, test device and test kit |
| JPS5666759A (en) * | 1979-11-05 | 1981-06-05 | Kazuo Hayashi | Measuring tube for radioimmunoassay used for clinical inspection |
| US4357240A (en) * | 1981-02-27 | 1982-11-02 | Sybron Corporation | Disposable, one-piece filter unit |
| US4424279A (en) * | 1982-08-12 | 1984-01-03 | Quidel | Rapid plunger immunoassay method and apparatus |
| US4458020A (en) * | 1982-11-15 | 1984-07-03 | Quidel | Integrated single tube plunger immunoassay system having plural reagent chambers |
-
1983
- 1983-10-21 US US06/544,177 patent/US4786471A/en not_active Expired - Fee Related
-
1984
- 1984-09-24 CA CA000463846A patent/CA1229300A/en not_active Expired
- 1984-10-09 AT AT84306888T patent/ATE49300T1/de not_active IP Right Cessation
- 1984-10-09 EP EP84306888A patent/EP0141547B1/en not_active Expired - Lifetime
- 1984-10-09 DE DE8484306888T patent/DE3480951D1/de not_active Expired - Lifetime
- 1984-10-19 JP JP59220306A patent/JPS60115865A/ja active Pending
- 1984-10-19 ES ES536947A patent/ES8606661A1/es not_active Expired
-
1986
- 1986-01-20 ES ES1986291778U patent/ES291778Y/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| ES291778Y (es) | 1987-01-16 |
| CA1229300A (en) | 1987-11-17 |
| EP0141547B1 (en) | 1990-01-03 |
| JPS60115865A (ja) | 1985-06-22 |
| US4786471A (en) | 1988-11-22 |
| ATE49300T1 (de) | 1990-01-15 |
| ES536947A0 (es) | 1986-04-01 |
| DE3480951D1 (de) | 1990-02-08 |
| ES8606661A1 (es) | 1986-04-01 |
| EP0141547A1 (en) | 1985-05-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1K | Utility model lapsed |
Effective date: 19970203 |