ES2984177T3 - Semaglutida en el tratamiento de la demencia de Alzheimer - Google Patents

Semaglutida en el tratamiento de la demencia de Alzheimer Download PDF

Info

Publication number: ES2984177T3
Authority: ES; Spain
Prior art keywords: glp; receptor agonist; dementia; semaglutide; disease
Prior art date: 2019-11-06
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Active

Application number

ES20803489T

Other languages

English (en)

Spanish (es)

Inventor

Sarah Friedrich

Charlotte Christine Thim Hansen

Lotte Bjerre Knudsen

Anna Secher

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Novo Nordisk AS

Original Assignee

Novo Nordisk AS

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2019-11-06

Filing date

2020-11-05

Publication date

2024-10-29

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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=73172681&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2984177(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2020-11-05 Application filed by Novo Nordisk AS filed Critical Novo Nordisk AS

2024-10-29 Application granted granted Critical

2024-10-29 Publication of ES2984177T3 publication Critical patent/ES2984177T3/es

Status Active legal-status Critical Current

2040-11-05 Anticipated expiration legal-status Critical

Links

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- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/26—Glucagons
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

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Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Veterinary Medicine (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Epidemiology (AREA)
Organic Chemistry (AREA)
Zoology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Immunology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Gastroenterology & Hepatology (AREA)
Endocrinology (AREA)
Psychiatry (AREA)
Hospice & Palliative Care (AREA)
Biophysics (AREA)
Molecular Biology (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicinal Preparation (AREA)
Peptides Or Proteins (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

ES20803489T 2019-11-06 2020-11-05 Semaglutida en el tratamiento de la demencia de Alzheimer Active ES2984177T3 (es)

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EP19207501		2019-11-06
EP20186623		2020-07-20
PCT/EP2020/081087 WO2021089678A1 (fr)	2019-11-06	2020-11-05	Agonistes du récepteur glp-1 dans la démence

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CN (1)	CN114728042A (fr)
AU (1)	AU2020377469A1 (fr)
BR (1)	BR112022007721A2 (fr)
CA (1)	CA3154744A1 (fr)
ES (1)	ES2984177T3 (fr)
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HU (1)	HUE067514T2 (fr)
IL (1)	IL291876A (fr)
MA (1)	MA57599B1 (fr)
MX (1)	MX2022004779A (fr)
PH (1)	PH12022550842A1 (fr)
PL (1)	PL4054620T3 (fr)
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HRP20241052T1 (hr)	2019-11-06	2024-11-08	Novo Nordisk A/S	Semaglutid, namijenjen liječenju alzheimerove demencije
US20230088005A1 (en) *	2020-01-30	2023-03-23	Eli Lilly And Company	Therapeutic uses of dulaglutide
CN118987224A (zh) *	2020-12-16	2024-11-22	香港中文大学	一种治疗受试者的衰老相关脑功能障碍的组合物及其应用
AU2022400245A1 (en)	2021-12-02	2024-05-30	Københavns Universitet	Peptide-drug conjugates for treatment of neurodegenerative diseases
CN120731085A (zh) *	2023-03-02	2025-09-30	甘李药业股份有限公司	一种glp-1化合物的医药用途
WO2026096637A1 (fr) *	2024-10-30	2026-05-07	Tiziana Life Sciences Plc	Agonistes de glp-1 et polythérapies à base de foralumab
CN120131965A (zh) *	2025-04-10	2025-06-13	瓯江实验室	Glp-1受体激动剂治疗阿尔茨海默病的用途

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JP3149958B2 (ja)	1996-08-30	2001-03-26	ノボノルディスクアクティーゼルスカブ	Ｇｌｐ―１誘導体
ATE309197T1 (de)	1999-02-05	2005-11-15	Emisphere Tech Inc	Verfahren zur herstellung alkylierter salicylamide
AU2001275231A1 (en)	2000-06-02	2001-12-11	Emisphere Technologies, Inc.	Method of preparing salicylamides
JP2005501058A (ja)	2001-07-31	2005-01-13	ザガバメントオブザユナイテッドステイツオブアメリカアズリプレゼンテッドバイザセクレタリーデパートメントオブヘルスアンドヒューマンサービシーズザナショナルインステ	Ｇｌｐ−１、ｅｘｅｎｄｉｎ−４、そのペプチド・アナログ及びその使用
TWI372629B (en)	2005-03-18	2012-09-21	Novo Nordisk As	Acylated glp-1 compounds
NZ565535A (en)	2005-06-30	2011-03-31	Ipsen Pharma Sas	GLP-1 pharmaceutical compositions
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BRPI0716539A2 (pt)	2006-09-07	2016-11-01	Emisphere Tech Inc	métodos para sintetização de ácido n-(8-[2-hidroxibenzoil]amino) caprílico e de sal de sódio deste
CA2784757A1 (fr)	2009-12-16	2011-07-07	Novo Nordisk A/S	Derives a double acylation de glp-1
US8703701B2 (en)	2009-12-18	2014-04-22	Indiana University Research And Technology Corporation	Glucagon/GLP-1 receptor co-agonists
PL2651398T3 (pl) *	2010-12-16	2018-05-30	Novo Nordisk A/S	Stałe kompozycje zawierające agonistę GLP-1 i sól kwasu N-(8-(2-hydroksybenzoilo)amino)kaprylowego
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RS67258B1 (sr) *	2012-07-01	2025-10-31	Novo Nordisk As	Upotreba dugodelujućih glp-1 peptida
ES2741507T3 (es)	2014-04-07	2020-02-11	Novo Nordisk As	Compuestos de glp-1 acilados doblemente
WO2016198624A1 (fr) *	2015-06-12	2016-12-15	Sanofi	Dérivés d'exendine 4 utilisés en tant qu'agonistes trigonaux des récepteurs du glp-1/glucagon/gip
US20170112897A1 (en)	2015-10-23	2017-04-27	Cedars-Sinai Medical Center	Methods for treating brain insulin resistance
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GB201620611D0 (en)	2016-12-05	2017-01-18	Univ Of Lancaster	Treatment of neurological diseases
HRP20241052T1 (hr)	2019-11-06	2024-11-08	Novo Nordisk A/S	Semaglutid, namijenjen liječenju alzheimerove demencije
PE20221575A1 (es)	2020-02-18	2022-10-06	Novo Nordisk As	Formulaciones farmaceuticas

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- 2020-11-05 EP EP24175772.3A patent/EP4414031A3/fr active Pending
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2022
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JP7670698B2 (ja)	2025-04-30
TWI890704B (zh)	2025-07-21
EP4054620C0 (fr)	2024-05-29
MA57599B1 (fr)	2024-06-28
EP4414031A2 (fr)	2024-08-14
JP2025027130A (ja)	2025-02-26
US20250099549A1 (en)	2025-03-27
US12539326B2 (en)	2026-02-03
IL291876A (en)	2022-06-01
WO2021089678A1 (fr)	2021-05-14
MX2022004779A (es)	2022-06-14
CN114728042A (zh)	2022-07-08
RS65780B1 (sr)	2024-08-30
US20240207364A1 (en)	2024-06-27
BR112022007721A2 (pt)	2022-07-12
EP4054620A1 (fr)	2022-09-14
EP4414031A3 (fr)	2025-02-05
TW202519256A (zh)	2025-05-16
KR20220110731A (ko)	2022-08-09
HRP20241052T1 (hr)	2024-11-08
PH12022550842A1 (en)	2023-10-09
US20230302094A1 (en)	2023-09-28
US20220280612A1 (en)	2022-09-08
EP4054620B1 (fr)	2024-05-29
JP2023500032A (ja)	2023-01-04
PL4054620T3 (pl)	2024-10-14
TW202118509A (zh)	2021-05-16
HUE067514T2 (hu)	2024-10-28
CA3154744A1 (fr)	2021-05-14
AU2020377469A1 (en)	2022-04-28

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Darshan	2017	Studies to Investigate the Influence of Ranolazine and Fluvastatin on the Pharmacokinetics and Pharmacodynamics of Glimepiride in Rats and Rabbits