ES345737A1 - Procedimiento para la obtencion de 2,3,4,4a,5,6-hexahidro- 1h-pirazino (1,2-a) quinolinas. - Google Patents

Procedimiento para la obtencion de 2,3,4,4a,5,6-hexahidro- 1h-pirazino (1,2-a) quinolinas.

Info

Publication number: ES345737A1
Authority: ES; Spain
Prior art keywords: pyrazino; aromatic ring; aliphatic; prepared; hexahydro
Prior art date: 1966-10-05
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired

Application number

ES345737A

Other languages

English (en)

Spanish (es)

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Novartis AG

BASF Schweiz AG

Original Assignee

Ciba Geigy AG

Ciba AG

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1966-10-05

Filing date

1967-10-04

Publication date

1969-01-16

1966-10-05 Priority claimed from CH1436366A external-priority patent/CH493546A/de

1967-10-04 Application filed by Ciba Geigy AG, Ciba AG filed Critical Ciba Geigy AG

1969-01-16 Publication of ES345737A1 publication Critical patent/ES345737A1/es

Status Expired legal-status Critical Current

Links

FXNGILFJMJFFBM-UHFFFAOYSA-N 1h-pyrazino[1,2-a]quinoline Chemical class C1=CC=C2N3CC=NC=C3C=CC2=C1 FXNGILFJMJFFBM-UHFFFAOYSA-N 0.000 title 1
238000004519 manufacturing process Methods 0.000 title 1
125000001931 aliphatic group Chemical group 0.000 abstract 2
125000000217 alkyl group Chemical group 0.000 abstract 2
125000003118 aryl group Chemical group 0.000 abstract 2
125000004432 carbon atom Chemical group C* 0.000 abstract 2
150000001875 compounds Chemical class 0.000 abstract 2
125000005843 halogen group Chemical group 0.000 abstract 2
CHIINPDGHUONJZ-UHFFFAOYSA-N 2,3,4,4a,5,6-hexahydro-1h-pyrazino[1,2-a]quinoline Chemical class C1=CC=C2N3CCNCC3CCC2=C1 CHIINPDGHUONJZ-UHFFFAOYSA-N 0.000 abstract 1
-1 CF 3 Chemical group 0.000 abstract 1
239000004215 Carbon black (E152) Substances 0.000 abstract 1
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
125000004442 acylamino group Chemical group 0.000 abstract 1
230000002908 adrenolytic effect Effects 0.000 abstract 1
125000003302 alkenyloxy group Chemical group 0.000 abstract 1
125000003545 alkoxy group Chemical group 0.000 abstract 1
SMWDFEZZVXVKRB-UHFFFAOYSA-N anhydrous quinoline Natural products N1=CC=CC2=CC=CC=C21 SMWDFEZZVXVKRB-UHFFFAOYSA-N 0.000 abstract 1
229940030600 antihypertensive agent Drugs 0.000 abstract 1
239000002220 antihypertensive agent Substances 0.000 abstract 1
150000001728 carbonyl compounds Chemical class 0.000 abstract 1
238000006264 debenzylation reaction Methods 0.000 abstract 1
239000003085 diluting agent Substances 0.000 abstract 1
125000000623 heterocyclic group Chemical group 0.000 abstract 1
229930195733 hydrocarbon Natural products 0.000 abstract 1
229910052739 hydrogen Inorganic materials 0.000 abstract 1
239000001257 hydrogen Substances 0.000 abstract 1
239000000543 intermediate Substances 0.000 abstract 1
125000004043 oxo group Chemical group O=* 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1
LMKOGFPNETZZTE-UHFFFAOYSA-N pyrido[2,3-f]quinoxaline Chemical class C1=CN=C2C3=NC=CC=C3C=CC2=N1 LMKOGFPNETZZTE-UHFFFAOYSA-N 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
229940125723 sedative agent Drugs 0.000 abstract 1
239000000932 sedative agent Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

ES345737A 1966-10-05 1967-10-04 Procedimiento para la obtencion de 2,3,4,4a,5,6-hexahidro- 1h-pirazino (1,2-a) quinolinas. Expired ES345737A1 (es)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
CH1436366A CH493546A (de)	1966-10-05	1966-10-05	Verfahren zur Herstellung neuer Pyrazino (1,2-a)-chinoline
CH156167		1967-02-02
CH1136467		1967-08-11

Publications (1)

Publication Number	Publication Date
ES345737A1 true ES345737A1 (es)	1969-01-16

Family

ID=27173077

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ES345737A Expired ES345737A1 (es)	1966-10-05	1967-10-04	Procedimiento para la obtencion de 2,3,4,4a,5,6-hexahidro- 1h-pirazino (1,2-a) quinolinas.

Country Status (7)

Country	Link
AT (2)	AT275526B (de)
BE (1)	BE704692A (de)
DE (1)	DE1670470A1 (de)
ES (1)	ES345737A1 (de)
FR (3)	FR1549375A (de)
GB (1)	GB1197326A (de)
NL (1)	NL6713505A (de)

1967
- 1967-09-27 DE DE19671670470 patent/DE1670470A1/de active Pending
- 1967-10-03 FR FR1549375D patent/FR1549375A/fr not_active Expired
- 1967-10-03 GB GB45005/67A patent/GB1197326A/en not_active Expired
- 1967-10-04 ES ES345737A patent/ES345737A1/es not_active Expired
- 1967-10-04 NL NL6713505A patent/NL6713505A/xx unknown
- 1967-10-04 BE BE704692D patent/BE704692A/xx unknown
- 1967-10-04 AT AT900867A patent/AT275526B/de active
- 1967-10-04 AT AT900967A patent/AT274812B/de active
- 1967-12-29 FR FR134281A patent/FR7111M/fr not_active Expired
- 1967-12-29 FR FR134280A patent/FR7110M/fr not_active Expired

Also Published As

Publication number	Publication date
FR7110M (de)	1969-07-15
DE1670470A1 (de)	1971-02-11
GB1197326A (en)	1970-07-01
AT274812B (de)	1969-10-10
BE704692A (de)	1968-04-04
NL6713505A (de)	1968-04-08
AT275526B (de)	1969-10-27
FR1549375A (de)	1968-12-13
FR7111M (de)	1969-07-15

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