ES408077A1 - Procedure for the preparation of arilalquil-pirril-aminoetanoles. (Machine-translation by Google Translate, not legally binding) - Google Patents

Procedure for the preparation of arilalquil-pirril-aminoetanoles. (Machine-translation by Google Translate, not legally binding)

Info

Publication number
ES408077A1
ES408077A1 ES408077A ES408077A ES408077A1 ES 408077 A1 ES408077 A1 ES 408077A1 ES 408077 A ES408077 A ES 408077A ES 408077 A ES408077 A ES 408077A ES 408077 A1 ES408077 A1 ES 408077A1
Authority
ES
Spain
Prior art keywords
arylalkyl
translation
procedure
preparation
machine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES408077A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Whitefin Holding SA
Original Assignee
Whitefin Holding SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Whitefin Holding SA filed Critical Whitefin Holding SA
Publication of ES408077A1 publication Critical patent/ES408077A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/33—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/335—Radicals substituted by nitrogen atoms not forming part of a nitro radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/33—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/337—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pain & Pain Management (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Procedure for the preparation of arylalkyl-pyrril-aminoethanoles of the formula **(See formula)** where R is an arylalkyl radical, and R1 and R2, the same or different, are straight or branched chain alkyl radicals with 1 to 4 carbon atoms, characterized in that: a) 1-arylalkyl-pyrrole is reacted with an oxalyl halide b) the thus formed 1-arylalkyl-2-pyrril-glyoxy halide is reacted with an amine of the formula HNR1R2, where R1 and R2 have the meaning indicated above, or with an acid addition salt thereof. c) the glyoxylamide thus reduced is reduced with a metal or organometallic hydride. (Machine-translation by Google Translate, not legally binding)
ES408077A 1971-10-30 1972-10-28 Procedure for the preparation of arilalquil-pirril-aminoetanoles. (Machine-translation by Google Translate, not legally binding) Expired ES408077A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT3058571 1971-10-30
IT3058671 1971-10-30

Publications (1)

Publication Number Publication Date
ES408077A1 true ES408077A1 (en) 1976-02-01

Family

ID=26328881

Family Applications (1)

Application Number Title Priority Date Filing Date
ES408077A Expired ES408077A1 (en) 1971-10-30 1972-10-28 Procedure for the preparation of arilalquil-pirril-aminoetanoles. (Machine-translation by Google Translate, not legally binding)

Country Status (12)

Country Link
JP (1) JPS5530514B2 (en)
CA (1) CA996941A (en)
CH (1) CH572909A5 (en)
CS (1) CS179403B2 (en)
DK (1) DK133670B (en)
ES (1) ES408077A1 (en)
FI (1) FI54705C (en)
HU (1) HU164701B (en)
NL (1) NL7214581A (en)
RO (1) RO62754A (en)
SE (1) SE396601B (en)
SU (1) SU453834A3 (en)

Also Published As

Publication number Publication date
SU453834A3 (en) 1974-12-15
CH572909A5 (en) 1976-02-27
DK133670B (en) 1976-06-28
RO62754A (en) 1982-09-09
FI54705B (en) 1978-10-31
NL7214581A (en) 1973-05-02
HU164701B (en) 1974-03-28
SE396601B (en) 1977-09-26
CA996941A (en) 1976-09-14
JPS5530514B2 (en) 1980-08-11
FI54705C (en) 1979-02-12
DK133670C (en) 1976-11-15
CS179403B2 (en) 1977-10-31
JPS4852765A (en) 1973-07-24

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