ES408279A1 - Procedimiento de fabricacion de la metilcobalamina por re- duccion y metilacion de la hidroxocobalamina. - Google Patents

Procedimiento de fabricacion de la metilcobalamina por re- duccion y metilacion de la hidroxocobalamina.

Info

Publication number: ES408279A1
Authority: ES; Spain
Prior art keywords: hydroxocobalamin; methylation; reduction; methylcobalamine; preparation
Prior art date: 1971-11-10
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired

Application number

ES408279A

Other languages

English (en)

Spanish (es)

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

OPOCHIMIE L

Original Assignee

OPOCHIMIE L

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1971-11-10

Filing date

1972-11-04

Publication date

1975-11-01

1972-11-04 Application filed by OPOCHIMIE L filed Critical OPOCHIMIE L

1975-11-01 Publication of ES408279A1 publication Critical patent/ES408279A1/es

Status Expired legal-status Critical Current

Links

YOZNUFWCRFCGIH-BYFNXCQMSA-L hydroxocobalamin Chemical compound O[Co+]N([C@]1([H])[C@H](CC(N)=O)[C@]\2(CCC(=O)NC[C@H](C)OP(O)(=O)OC3[C@H]([C@H](O[C@@H]3CO)N3C4=CC(C)=C(C)C=C4N=C3)O)C)C/2=C(C)\C([C@H](C/2(C)C)CCC(N)=O)=N\C\2=C\C([C@H]([C@@]/2(CC(N)=O)C)CCC(N)=O)=N\C\2=C(C)/C2=N[C@]1(C)[C@@](C)(CC(N)=O)[C@@H]2CCC(N)=O YOZNUFWCRFCGIH-BYFNXCQMSA-L 0.000 abstract 4
235000004867 hydroxocobalamin Nutrition 0.000 abstract 2
239000011704 hydroxocobalamin Substances 0.000 abstract 2
229960001103 hydroxocobalamin Drugs 0.000 abstract 2
230000011987 methylation Effects 0.000 abstract 2
238000007069 methylation reaction Methods 0.000 abstract 2
238000004519 manufacturing process Methods 0.000 abstract 1
125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
235000007672 methylcobalamin Nutrition 0.000 abstract 1
239000011585 methylcobalamin Substances 0.000 abstract 1
JEWJRMKHSMTXPP-BYFNXCQMSA-M methylcobalamin Chemical compound C[Co+]N([C@]1([H])[C@H](CC(N)=O)[C@]\2(CCC(=O)NC[C@H](C)OP(O)(=O)OC3[C@H]([C@H](O[C@@H]3CO)N3C4=CC(C)=C(C)C=C4N=C3)O)C)C/2=C(C)\C([C@H](C/2(C)C)CCC(N)=O)=N\C\2=C\C([C@H]([C@@]/2(CC(N)=O)C)CCC(N)=O)=N\C\2=C(C)/C2=N[C@]1(C)[C@@](C)(CC(N)=O)[C@@H]2CCC(N)=O JEWJRMKHSMTXPP-BYFNXCQMSA-M 0.000 abstract 1
239000000843 powder Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H23/00—Compounds containing boron, silicon or a metal, e.g. chelates or vitamin B12

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Biochemistry (AREA)
Biotechnology (AREA)
General Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Saccharide Compounds (AREA)
Catalysts (AREA)

ES408279A 1971-11-10 1972-11-04 Procedimiento de fabricacion de la metilcobalamina por re- duccion y metilacion de la hidroxocobalamina. Expired ES408279A1 (es)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
FR7140233A FR2159720A5 (de)	1971-11-10	1971-11-10

Publications (1)

Publication Number	Publication Date
ES408279A1 true ES408279A1 (es)	1975-11-01

Family

ID=9085580

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ES408279A Expired ES408279A1 (es)	1971-11-10	1972-11-04	Procedimiento de fabricacion de la metilcobalamina por re- duccion y metilacion de la hidroxocobalamina.

Country Status (21)

Country	Link
JP (1)	JPS51120B2 (de)
AR (1)	AR192677A1 (de)
AT (1)	AT330374B (de)
AU (1)	AU464986B2 (de)
BE (1)	BE789252A (de)
BR (1)	BR7207834D0 (de)
CA (1)	CA972746A (de)
CH (1)	CH545299A (de)
DE (1)	DE2255203A1 (de)
DK (1)	DK133381B (de)
ES (1)	ES408279A1 (de)
FR (1)	FR2159720A5 (de)
GB (1)	GB1355899A (de)
IE (1)	IE36822B1 (de)
IL (1)	IL40762A (de)
LU (1)	LU66165A1 (de)
NL (1)	NL153548B (de)
NO (1)	NO137095C (de)
OA (1)	OA04191A (de)
SE (1)	SE383350B (de)
ZA (1)	ZA727831B (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NO742545L (de) *	1973-08-08	1975-03-10	Opochimie L
JPS583753Y2 (ja) *	1978-08-25	1983-01-22	日立造船株式会社	海上構造物の接続装置
JPH0422432A (ja) *	1990-05-18	1992-01-27	Maruyama Mfg Co Ltd	散布液タンクにおける散布液攪拌方法及び装置
DE60026354T2 (de)	1999-12-09	2006-11-09	Eisai Co., Ltd.	Verfahren zur herstellung von methylcobalamin
JP4358615B2 (ja)	2001-06-05	2009-11-04	エーザイ・アール・アンド・ディー・マネジメント株式会社	メチルコバラミンの製造法
WO2018007035A1 (en) *	2016-07-08	2018-01-11	Interquim, S.A.	Process for the purification of methylcobalamin

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE1178073B (de) *	1961-06-09	1964-09-17	Merck Ag E	Verfahren zur Herstellung von Vitamin B und dessen stabilen Loesungen
FR1450375A (fr) *	1961-12-11	1966-06-24	Glaxo Group Ltd	Procédé de préparation d'un co-enzyme de vitamine b12 et d'analogues de celui-ci
DE1213842B (de) *	1962-04-27	1966-04-07	Hoffmann La Roche	Verfahren zur Herstellung von Co-R-Cobamiden

0
- BE BE789252D patent/BE789252A/xx unknown
1971
- 1971-11-10 FR FR7140233A patent/FR2159720A5/fr not_active Expired
1972
- 1972-09-25 DK DK472172AA patent/DK133381B/da unknown
- 1972-09-26 NO NO3443/72A patent/NO137095C/no unknown
- 1972-09-26 LU LU66165A patent/LU66165A1/xx unknown
- 1972-10-03 OA OA54710A patent/OA04191A/xx unknown
- 1972-10-24 NL NL727214368A patent/NL153548B/xx unknown
- 1972-11-01 GB GB5032472A patent/GB1355899A/en not_active Expired
- 1972-11-01 SE SE7214155A patent/SE383350B/xx unknown
- 1972-11-02 IE IE1494/72A patent/IE36822B1/xx unknown
- 1972-11-02 CA CA155,413A patent/CA972746A/en not_active Expired
- 1972-11-03 ZA ZA727831A patent/ZA727831B/xx unknown
- 1972-11-04 ES ES408279A patent/ES408279A1/es not_active Expired
- 1972-11-07 IL IL40762A patent/IL40762A/xx unknown
- 1972-11-07 AU AU48582/72A patent/AU464986B2/en not_active Expired
- 1972-11-07 AT AT945672A patent/AT330374B/de not_active IP Right Cessation
- 1972-11-08 CH CH1627072A patent/CH545299A/fr not_active IP Right Cessation
- 1972-11-08 BR BR7834/72A patent/BR7207834D0/pt unknown
- 1972-11-09 JP JP47111724A patent/JPS51120B2/ja not_active Expired
- 1972-11-09 AR AR245050A patent/AR192677A1/es active
- 1972-11-10 DE DE2255203A patent/DE2255203A1/de active Pending

Also Published As

Publication number	Publication date
BE789252A (fr)	1973-03-26
NL7214368A (de)	1973-05-14
OA04191A (fr)	1979-12-31
DE2255203A1 (de)	1973-05-17
DK133381B (da)	1976-05-10
CA972746A (en)	1975-08-12
IE36822L (en)	1973-05-10
ZA727831B (en)	1973-07-25
IE36822B1 (en)	1977-03-02
JPS51120B2 (de)	1976-01-05
IL40762A (en)	1975-07-28
FR2159720A5 (de)	1973-06-22
NO137095B (no)	1977-09-19
LU66165A1 (de)	1974-04-02
JPS4947399A (de)	1974-05-08
AU464986B2 (en)	1975-09-11
NO137095C (no)	1977-12-28
DK133381C (de)	1976-10-04
SE383350B (sv)	1976-03-08
AR192677A1 (es)	1973-02-28
IL40762A0 (en)	1973-01-30
NL153548B (nl)	1977-06-15
BR7207834D0 (pt)	1973-09-20
CH545299A (fr)	1973-12-15
GB1355899A (en)	1974-06-05
AT330374B (de)	1976-06-25
AU4858272A (en)	1974-05-09
ATA945672A (de)	1975-09-15

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