ES440079A1 - Procedimiento para preparar nuevos derivados del acido 3- quinoleincarboxilico. - Google Patents

Procedimiento para preparar nuevos derivados del acido 3- quinoleincarboxilico.

Info

Publication number: ES440079A1
Authority: ES; Spain
Prior art keywords: group; carboxamides; quinoline; oxy; substituted
Prior art date: 1974-08-13
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired

Application number

ES440079A

Other languages

English (en)

Spanish (es)

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Sanofi Aventis France

Original Assignee

Roussel Uclaf SA

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1974-08-13

Filing date

1975-08-07

Publication date

1977-02-16

1975-08-07 Application filed by Roussel Uclaf SA filed Critical Roussel Uclaf SA

1977-02-16 Publication of ES440079A1 publication Critical patent/ES440079A1/es

Status Expired legal-status Critical Current

Links

125000004432 carbon atom Chemical group C* 0.000 abstract 2
229910052739 hydrogen Inorganic materials 0.000 abstract 2
239000001257 hydrogen Substances 0.000 abstract 2
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
239000002253 acid Substances 0.000 abstract 1
125000002252 acyl group Chemical group 0.000 abstract 1
150000007933 aliphatic carboxylic acids Chemical class 0.000 abstract 1
125000000217 alkyl group Chemical group 0.000 abstract 1
230000000202 analgesic effect Effects 0.000 abstract 1
229910052736 halogen Inorganic materials 0.000 abstract 1
125000005843 halogen group Chemical group 0.000 abstract 1
239000000543 intermediate Substances 0.000 abstract 1
231100000252 nontoxic Toxicity 0.000 abstract 1
230000003000 nontoxic effect Effects 0.000 abstract 1
125000002971 oxazolyl group Chemical group 0.000 abstract 1
125000004076 pyridyl group Chemical group 0.000 abstract 1
BLTDCIWCFCUQCB-UHFFFAOYSA-N quinoline-3-carboxamide Chemical class C1=CC=CC2=CC(C(=O)N)=CN=C21 BLTDCIWCFCUQCB-UHFFFAOYSA-N 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
125000000876 trifluoromethoxy group Chemical group FC(F)(F)O* 0.000 abstract 1
125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
- C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Pain & Pain Management (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Biomedical Technology (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Quinoline Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

ES440079A 1974-08-13 1975-08-07 Procedimiento para preparar nuevos derivados del acido 3- quinoleincarboxilico. Expired ES440079A1 (es)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
FR7428038A FR2281761A1 (fr)	1974-08-13	1974-08-13	Nouveaux derives de l'acide 3-quinoleine carboxylique, leur procede de preparation et leur application comme medicament

Publications (1)

Publication Number	Publication Date
ES440079A1 true ES440079A1 (es)	1977-02-16

Family

ID=9142372

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ES440079A Expired ES440079A1 (es)	1974-08-13	1975-08-07	Procedimiento para preparar nuevos derivados del acido 3- quinoleincarboxilico.

Country Status (21)

Country	Link
US (1)	US3992540A (2)
JP (1)	JPS5925793B2 (2)
AR (1)	AR208323A1 (2)
AT (1)	AT340928B (2)
BE (1)	BE832332A (2)
CA (1)	CA1055499A (2)
CH (1)	CH614953A5 (2)
DD (1)	DD122972A5 (2)
DE (1)	DE2536206C2 (2)
DK (1)	DK142319B (2)
ES (1)	ES440079A1 (2)
FR (1)	FR2281761A1 (2)
GB (1)	GB1484787A (2)
HU (1)	HU170060B (2)
IE (1)	IE41841B1 (2)
IL (1)	IL47820A (2)
LU (1)	LU73193A1 (2)
NL (1)	NL7509625A (2)
SE (1)	SE425244B (2)
SU (1)	SU566522A3 (2)
ZA (1)	ZA754905B (2)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2340735A1 (fr) *	1976-02-11	1977-09-09	Roussel Uclaf	Nouveaux derives de l'acide 3-quinoleine carboxylique, leur procede de preparation et leur application comme medicament
FR2443467A1 (fr) *	1978-12-08	1980-07-04	Roussel Uclaf	Nouveaux derives de l'acide 3-quinoleine carboxylique, leur procede de preparation et leur application comme medicament
FR2482596A1 (fr) *	1980-05-19	1981-11-20	Roussel Uclaf	Nouveaux derives de l'acide 4-hydroxy 3-quinoleine carboxylique substitues en 2, leur procede de preparation et leur application comme medicament
IE52670B1 (en) *	1981-03-03	1988-01-20	Leo Ab	Heterocyclic carboxamides,compositions containing such compounds,and processes for their preparation
FR2507602A1 (fr) *	1981-06-12	1982-12-17	Roussel Uclaf	Nouveau derive dihydrothiazole de la quinoleine, ses sels, procede de preparation, application a titre de medicaments et compositions les renfermant
HU190796B (en) *	1981-06-12	1986-11-28	Roussel Uclaf,Fr	Process for producing n-dihydrothiazolyl-3-quinoline-carboxamide derivatives
FR2523130A1 (fr) *	1982-03-15	1983-09-16	Roussel Uclaf	Nouveaux derives de la n-dihydrothiazolyl-3-quinoleine carboxamide, leurs sels, procede de preparation, application a titre de medicaments et compositions les renfermant
FR2509728A1 (fr) *	1981-07-17	1983-01-21	Roussel Uclaf	Nouveaux derives de la quinoleine, leurs sels, procede de preparation, application a titre de medicaments et compositions les renfermant
FR2537140B1 (fr) *	1982-12-07	1986-07-18	Roussel Uclaf	Nouveaux derives de la 4-hydroxy-3-quinoleine carboxamide, leur sels, procede de preparation, application a titre de medicaments, et compositions les renfermant
FR2566405B1 (fr) *	1984-06-25	1986-09-26	Roussel Uclaf	Nouveaux derives de l'acide 4-hydroxy 3-quinoleine carboxylique substitues en 2 par une fonction aminee, leur preparation, leur application comme medicaments, les compositions les renfermant et les intermediaires nouveaux obtenus
US4602014A (en) *	1984-07-09	1986-07-22	Ciba-Geigy Corporation	Ring-fused pyrazolo[3,4-d]-pyridin-3-one derivatives as benzodiazepine receptor modulators
US4689182A (en) *	1985-12-20	1987-08-25	Warner-Lambert Company	Benzoic acid and benzoic acid ester derivatives having anti-inflammatory and analgesic activity
US4990533A (en) *	1985-12-20	1991-02-05	Warner-Lambert Co.	Benzoic acid and benzoic acid ester derivatives having anti-inflammatory and analgesic activity
CN101891680B (zh)	2004-06-24	2014-10-29	沃泰克斯药物股份有限公司	Atp-结合弹夹转运蛋白的调控剂
US8354427B2 (en)	2004-06-24	2013-01-15	Vertex Pharmaceutical Incorporated	Modulators of ATP-binding cassette transporters
CN101374849A (zh) *	2005-12-24	2009-02-25	沃泰克斯药物股份有限公司	作为abc转运蛋白调控剂的喹啉-4-酮衍生物
DK3219705T3 (da)	2005-12-28	2020-04-14	Vertex Pharma	Farmaceutiske sammensætninger af den amorfe form af n-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinolin-3-carboxamid
US20100074949A1 (en)	2008-08-13	2010-03-25	William Rowe	Pharmaceutical composition and administration thereof
US12458635B2 (en)	2008-08-13	2025-11-04	Vertex Pharmaceuticals Incorporated	Pharmaceutical composition and administrations thereof
KR101727762B1 (ko)	2009-03-20	2017-04-17	버텍스 파마슈티칼스 인코포레이티드	낭성 섬유증 막횡단 전도도 조절자의 조정자의 제조 방법
US8802700B2 (en)	2010-12-10	2014-08-12	Vertex Pharmaceuticals Incorporated	Modulators of ATP-Binding Cassette transporters
JP2015511583A (ja)	2012-02-27	2015-04-20	バーテックスファーマシューティカルズインコーポレイテッドＶｅｒｔｅｘＰｈａｒｍａｃｅｕｔｉｃａｌｓＩｎｃｏｒｐｏｒａｔｅｄ	薬学的組成物およびその投与
CN107250113B (zh)	2014-10-07	2019-03-29	弗特克斯药品有限公司	囊性纤维化跨膜传导调节蛋白的调节剂的共晶

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CH71A (de) *	1888-11-15	1889-06-13	Th Hunziker	Apparat zum Absticken verlängerter Nädlinge für Handstickmaschinen
US2798070A (en) *	1954-02-04	1957-07-02	Mcneilab Inc	Quaternary quinoline carboxamide salts and method of preparing same
JPS4323948Y1 (2) *	1965-03-06	1968-10-09
US3524858A (en) *	1967-05-18	1970-08-18	Warner Lambert Pharmaceutical	1,4 - dihydro-1-substituted alkyl-6,7-methylenedioxy - 4 - oxoquinoline-3-carboxylic acid
US3496184A (en) *	1969-03-18	1970-02-17	Ciba Geigy Corp	Cyclopropylmethoxy-3-quinoline carboxylic acids and esters

1974
- 1974-08-13 FR FR7428038A patent/FR2281761A1/fr active Granted
1975
- 1975-01-01 AR AR259945A patent/AR208323A1/es active
- 1975-07-22 SE SE7508332A patent/SE425244B/xx not_active IP Right Cessation
- 1975-07-25 IL IL47820A patent/IL47820A/xx unknown
- 1975-07-28 US US05/599,369 patent/US3992540A/en not_active Expired - Lifetime
- 1975-07-30 ZA ZA00754905A patent/ZA754905B/xx unknown
- 1975-08-01 SU SU7502159095A patent/SU566522A3/ru active
- 1975-08-06 DD DD187721A patent/DD122972A5/xx unknown
- 1975-08-07 JP JP50095466A patent/JPS5925793B2/ja not_active Expired
- 1975-08-07 ES ES440079A patent/ES440079A1/es not_active Expired
- 1975-08-11 CA CA233,230A patent/CA1055499A/en not_active Expired
- 1975-08-12 IE IE1796/75A patent/IE41841B1/en unknown
- 1975-08-12 BE BE159113A patent/BE832332A/xx not_active IP Right Cessation
- 1975-08-12 CH CH1048375A patent/CH614953A5/xx not_active IP Right Cessation
- 1975-08-12 LU LU73193A patent/LU73193A1/xx unknown
- 1975-08-12 GB GB33609/75A patent/GB1484787A/en not_active Expired
- 1975-08-13 DE DE2536206A patent/DE2536206C2/de not_active Expired
- 1975-08-13 DK DK366175AA patent/DK142319B/da not_active IP Right Cessation
- 1975-08-13 AT AT630875A patent/AT340928B/de not_active IP Right Cessation
- 1975-08-13 NL NL7509625A patent/NL7509625A/xx not_active Application Discontinuation
- 1975-08-13 HU HURO850A patent/HU170060B/hu not_active IP Right Cessation

Also Published As

Publication number	Publication date
GB1484787A (en)	1977-09-08
AR208323A1 (es)	1976-12-20
ATA630875A (de)	1977-05-15
CA1055499A (en)	1979-05-29
CH614953A5 (2)	1979-12-28
DK142319C (2)	1981-03-02
JPS5925793B2 (ja)	1984-06-21
SE7508332L (sv)	1976-02-16
NL7509625A (nl)	1976-02-17
LU73193A1 (2)	1976-08-13
DK366175A (2)	1976-02-14
DE2536206A1 (de)	1976-03-04
FR2281761A1 (fr)	1976-03-12
AT340928B (de)	1978-01-10
BE832332A (fr)	1976-02-12
ZA754905B (en)	1976-08-25
AU8340875A (en)	1977-01-27
DE2536206C2 (de)	1984-07-19
IE41841B1 (en)	1980-04-09
FR2281761B1 (2)	1978-07-28
DD122972A5 (de)	1976-11-12
IE41841L (en)	1976-02-13
JPS5141366A (en)	1976-04-07
IL47820A (en)	1978-10-31
IL47820A0 (en)	1975-10-15
HU170060B (2)	1977-03-28
DK142319B (da)	1980-10-13
SU566522A3 (ru)	1977-07-25
US3992540A (en)	1976-11-16
SE425244B (sv)	1982-09-13

Publication	Publication Date	Title
IE41841L (en)	1976-02-13	3-quinoline carboxylic acid amides
ES455804A1 (es)	1978-01-16	Un procedimiento de preparacion de nuevos derivados del aci-do 3-quinolein- carboxilico.
ES452763A1 (es)	1977-10-01	Procedimiento para la preparacion de nuevos 2-tetrahidrofur-furil-6, 7-benzomorfanos disustituidos en 5, 9-beta.
ES431514A1 (es)	1976-11-01	Procedimiento para la preparacion de 2 - (heteroaril-metil)-5,9 beta - dialcohil-6,7-benzomorfanos.
ES429710A1 (es)	1976-08-16	Un procedimiento para la preparacion de nuevos n,n'-bis- (beta-hidroxi-ariletil)-diaminoalcanos.
ES405983A1 (es)	1975-09-16	Procedimiento para la preparacion de derivados de fenileti-lamina fluoralcohilados.
GB1369248A (en)	1974-10-02	Amides the preparation thereof and their use in pharmacjeutical compositions
ES447922A1 (es)	1977-06-16	Procedimiento de preparacion de nuevos derivados sustitui- dos en n de la fenil-piperidina.
ES8304567A1 (es)	1983-03-01	"un procedimiento para preparar nuevos derivados de la n-dihidrotiazolil-3-quinolein-carboxamida".
ES473925A1 (es)	1980-01-16	Un procedimiento para la preparacion de un oligopeptido
ES439927A1 (es)	1977-06-01	Procedimiento para la obtencion de 7-metoxi-6-tiatetracicli-nas.
ES463240A1 (es)	1978-09-01	Procedimiento para la preparacion de acidos pirazol-1-il-fe-nilaceticos.
ES395481A1 (es)	1973-12-16	Procedimiento para la preparacion de compuestos de nafti- lalcohilaminas.
ES460218A1 (es)	1978-04-01	Procedimiento para preparar derivados de fenetilamina.
IE43830L (en)	1976-11-16	Phenylpiperidine derivatives.
ES427115A1 (es)	1976-07-16	Procedimiento de preparacion de nuevos derivados del acido acetico.
ES425010A1 (es)	1976-06-16	Procedimiento para la preparacion de n-(heteroaril-metil)- 6,14-endoetno-7 a-hidrovialcohil-tetrahidro-nororipavinas y tebainas.
ES424307A1 (es)	1976-07-01	Procedimiento para la preparacion de n-(heteroarilmetil)-7-alfa - acil - 6,14-endoeteno - tetrahidronororipavinas y te-bainas.
ES419782A1 (es)	1976-05-01	Un procedimiento para preparar nuevos esteres y amidas de acidos 3-aril, 1,4 benzodiaxan-2-carboxilicos.
ES449446A1 (es)	1977-12-01	Un procedimiento para la produccion de acidos 1-oxo-1h-6-pi-peridinogicamente activos y esteres de los mismos.
ES401174A1 (es)	1975-09-01	Procedimiento para la preparacion de nuevos esteres alcohi-licos del acido tiolcarbamidico basicamente sustituidos.
ES433957A1 (es)	1976-11-16	Un procedimiento de preparacion de nuevas fenotiazinas.
US4027030A (en)	1977-05-31	Certain thiazole-carboxamides and their pharmaceutical utility
ES419432A1 (es)	1976-04-01	Procedimiento de preparacion de derivados de 5-metil-11-(b-alcohilaminoetil) (5h) dibenzo (b,f) azepinas.
ES457996A1 (es)	1978-02-01	Un procedimiento para la preparacion de nuevos derivados de morfolina.