ES450601A1 - Un procedimiento para la preparacion de nuevos derivados de 4,5-diaril-2-(tiosustituido) michazol. - Google Patents

Un procedimiento para la preparacion de nuevos derivados de 4,5-diaril-2-(tiosustituido) michazol.

Info

Publication number: ES450601A1
Authority: ES; Spain
Prior art keywords: treatment; inflammatory; compounds; useful; unique properties
Prior art date: 1975-08-11
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired

Application number

ES450601A

Other languages

English (en)

Spanish (es)

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

EIDP Inc

Original Assignee

EI Du Pont de Nemours and Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1975-08-11

Filing date

1976-08-10

Publication date

1978-01-16

1976-08-10 Application filed by EI Du Pont de Nemours and Co filed Critical EI Du Pont de Nemours and Co

1978-01-16 Publication of ES450601A1 publication Critical patent/ES450601A1/es

Status Expired legal-status Critical Current

Links

150000002460 imidazoles Chemical class 0.000 title abstract 2
230000003110 anti-inflammatory effect Effects 0.000 abstract 2
150000001875 compounds Chemical class 0.000 abstract 2
201000010099 disease Diseases 0.000 abstract 2
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
206010003246 arthritis Diseases 0.000 abstract 1
238000003556 assay Methods 0.000 abstract 1
230000004957 immunoregulator effect Effects 0.000 abstract 1
239000003018 immunosuppressive agent Substances 0.000 abstract 1
229940124589 immunosuppressive drug Drugs 0.000 abstract 1
229940021182 non-steroidal anti-inflammatory drug Drugs 0.000 abstract 1
206010039073 rheumatoid arthritis Diseases 0.000 abstract 1
125000000446 sulfanediyl group Chemical group *S* 0.000 abstract 1
125000001174 sulfone group Chemical group 0.000 abstract 1
150000003462 sulfoxides Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/84—Sulfur atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pain & Pain Management (AREA)
Pharmacology & Pharmacy (AREA)
Rheumatology (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

ES450601A 1975-08-11 1976-08-10 Un procedimiento para la preparacion de nuevos derivados de 4,5-diaril-2-(tiosustituido) michazol. Expired ES450601A1 (es)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US60365075A	1975-08-11	1975-08-11
US69128276A	1976-06-09	1976-06-09

Publications (1)

Publication Number	Publication Date
ES450601A1 true ES450601A1 (es)	1978-01-16

Family

ID=27084480

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
ES450601A Expired ES450601A1 (es)	1975-08-11	1976-08-10	Un procedimiento para la preparacion de nuevos derivados de 4,5-diaril-2-(tiosustituido) michazol.
ES461193A Expired ES461193A1 (es)	1975-08-11	1977-07-28	Un procedimiento para la preparacion de nuevos derivados de 4,5diaril-2-(tio sustituido) imidazol.

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
ES461193A Expired ES461193A1 (es)	1975-08-11	1977-07-28	Un procedimiento para la preparacion de nuevos derivados de 4,5diaril-2-(tio sustituido) imidazol.

Country Status (26)

Country	Link
JP (1)	JPS6011702B2 (2)
AR (2)	AR215591A1 (2)
AU (1)	AU508605B2 (2)
CA (1)	CA1074327A (2)
CH (1)	CH638791A5 (2)
DD (1)	DD126244A5 (2)
DE (1)	DE2635876A1 (2)
DK (1)	DK361376A (2)
ES (2)	ES450601A1 (2)
FI (1)	FI66177C (2)
FR (1)	FR2320745A1 (2)
GB (1)	GB1516908A (2)
GR (1)	GR61145B (2)
HU (1)	HU174707B (2)
IE (1)	IE44019B1 (2)
IL (1)	IL50230A (2)
LU (1)	LU75578A1 (2)
MX (1)	MX3932E (2)
NL (1)	NL7608915A (2)
NO (1)	NO146571C (2)
NZ (1)	NZ181731A (2)
PH (1)	PH11857A (2)
PT (1)	PT65464B (2)
SE (1)	SE428686B (2)
SU (1)	SU640662A3 (2)
YU (1)	YU198176A (2)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DK16778A (da) *	1977-02-09	1978-08-10	Du Pont	Imidazolderivater deres anvendelser og fremstilling
LU77703A1 (de) *	1977-07-07	1979-03-26	Ciba Geigy Ag	Verfahren zur herstellung von bicyclischen thia-diaza-verbindungen
EP0004648B1 (de) *	1978-04-11	1982-08-25	Ciba-Geigy Ag	Neue Mercaptoimidazolderivate, Verfahren zu deren Herstellung, Mercaptoimidazolderivate zur Behandlung entzündlicher Erkrankungen und diese enthaltende pharmazeutische Präparate
DE2823197A1 (de) *	1978-05-24	1979-11-29	Schering Ag	Neue imidazolderivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate
US4308277A (en) *	1978-08-10	1981-12-29	Ciba-Geigy Corporation	2,4,5-Trisubstituted imidazolines and pharmaceutical compositions containing same
US4188397A (en) *	1978-09-22	1980-02-12	Smithkline Corporation	2,2-Alkyldiylbis(thio)bis(imidazoles)
US4215135A (en) *	1979-06-08	1980-07-29	E. I. Du Pont De Nemours And Company	Antiinflammatory 2-substituted-1H-phenanthro[9,10-d]imidazoles
DE2856909A1 (de) *	1978-12-28	1980-07-17	Schering Ag	Neue imidazolderivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate
GB8907656D0 (en) *	1989-04-05	1989-05-17	May & Baker Ltd	New compositions of matter
DK0786455T3 (da) *	1994-09-26	2004-03-29	Shionogi & Co	Imidazolderivater
AU8757098A (en) *	1997-06-30	1999-02-10	Ortho-Mcneil Pharmaceutical, Inc.	2-substituted imidazoles useful in the treatment of inflammatory diseases
DE10222103A1 (de) *	2002-05-17	2003-11-27	Merckle Gmbh Chem Pharm Fabrik	2-Thio-substituierte Imidazolderivate und ihre Verwendung in der Pharmazie
CN101415687B (zh) *	2006-02-06	2012-02-08	大正制药株式会社	鞘氨醇-1-磷酸结合抑制物质

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
BE688585A (2) *	1965-10-21	1967-04-20
US3651080A (en) *	1969-11-07	1972-03-21	Ciba Geigy Corp	Certain substituted 2-alkylmercaptoimidazole derivatives
US3636003A (en) *	1969-11-17	1972-01-18	Geigy Chem Corp	Substituted 2-mercaptoimidazole derivatives
US3714179A (en) *	1970-09-08	1973-01-30	Searle & Co	1-alkyl-2-furfurylthioimidazoles and congeners
US3707475A (en) *	1970-11-16	1972-12-26	Pfizer	Antiinflammatory imidazoles

1976
- 1976-07-02 SE SE7607615A patent/SE428686B/xx not_active IP Right Cessation
- 1976-08-05 MX MX762132U patent/MX3932E/es unknown
- 1976-08-09 NO NO762754A patent/NO146571C/no unknown
- 1976-08-09 CA CA258,690A patent/CA1074327A/en not_active Expired
- 1976-08-09 DD DD194248A patent/DD126244A5/xx unknown
- 1976-08-10 IL IL50230A patent/IL50230A/xx unknown
- 1976-08-10 PH PH18773A patent/PH11857A/en unknown
- 1976-08-10 FR FR7624400A patent/FR2320745A1/fr active Granted
- 1976-08-10 AU AU16711/76A patent/AU508605B2/en not_active Expired
- 1976-08-10 NZ NZ181737A patent/NZ181731A/xx unknown
- 1976-08-10 FI FI762290A patent/FI66177C/fi not_active IP Right Cessation
- 1976-08-10 DE DE19762635876 patent/DE2635876A1/de not_active Withdrawn
- 1976-08-10 DK DK361376A patent/DK361376A/da not_active Application Discontinuation
- 1976-08-10 PT PT65464A patent/PT65464B/pt unknown
- 1976-08-10 CH CH1019276A patent/CH638791A5/de not_active IP Right Cessation
- 1976-08-10 SU SU762388413A patent/SU640662A3/ru active
- 1976-08-10 GR GR51440A patent/GR61145B/el unknown
- 1976-08-10 ES ES450601A patent/ES450601A1/es not_active Expired
- 1976-08-10 HU HU76DU252A patent/HU174707B/hu unknown
- 1976-08-10 GB GB33286/76A patent/GB1516908A/en not_active Expired
- 1976-08-11 NL NL7608915A patent/NL7608915A/xx not_active Application Discontinuation
- 1976-08-11 IE IE1775/76A patent/IE44019B1/en unknown
- 1976-08-11 JP JP51094991A patent/JPS6011702B2/ja not_active Expired
- 1976-08-11 LU LU75578A patent/LU75578A1/xx unknown
- 1976-08-11 AR AR264308A patent/AR215591A1/es active
- 1976-08-11 YU YU01981/76A patent/YU198176A/xx unknown
1977
- 1977-07-28 ES ES461193A patent/ES461193A1/es not_active Expired
1978
- 1978-01-10 AR AR270672A patent/AR218054A1/es active

Also Published As

Publication number	Publication date
NO146571C (no)	1982-10-27
CA1074327A (en)	1980-03-25
YU198176A (en)	1982-10-31
IL50230A (en)	1979-07-25
MX3932E (es)	1981-10-02
DD126244A5 (2)	1977-07-06
GR61145B (en)	1978-09-27
HU174707B (hu)	1980-03-28
PT65464A (en)	1976-09-01
NO146571B (no)	1982-07-19
SU640662A3 (ru)	1978-12-30
IL50230A0 (en)	1976-10-31
JPS5223076A (en)	1977-02-21
LU75578A1 (2)	1978-04-13
FI66177B (fi)	1984-05-31
JPS6011702B2 (ja)	1985-03-27
FR2320745B1 (2)	1978-12-22
DE2635876A1 (de)	1977-03-03
ES461193A1 (es)	1978-12-01
GB1516908A (en)	1978-07-05
IE44019B1 (en)	1981-07-29
NO762754L (2)	1977-02-14
FI762290A7 (2)	1977-02-12
SE428686B (sv)	1983-07-18
FI66177C (fi)	1984-09-10
AU508605B2 (en)	1980-03-27
PT65464B (en)	1978-08-02
NZ181731A (en)	1978-11-13
AR215591A1 (es)	1979-10-31
CH638791A5 (de)	1983-10-14
AU1671176A (en)	1978-02-16
PH11857A (en)	1978-08-03
SE7607615L (sv)	1977-02-12
NL7608915A (nl)	1977-02-15
IE44019L (en)	1977-02-11
FR2320745A1 (fr)	1977-03-11
AR218054A1 (es)	1980-05-15
DK361376A (da)	1977-02-12

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