ES460645A1 - Procedimiento de obtencion del acido 2-fosfonoxibenzoico y sales del mismo. - Google Patents
Procedimiento de obtencion del acido 2-fosfonoxibenzoico y sales del mismo.Info
- Publication number
- ES460645A1 ES460645A1 ES460645A ES460645A ES460645A1 ES 460645 A1 ES460645 A1 ES 460645A1 ES 460645 A ES460645 A ES 460645A ES 460645 A ES460645 A ES 460645A ES 460645 A1 ES460645 A1 ES 460645A1
- Authority
- ES
- Spain
- Prior art keywords
- prepd
- phosphonoxy
- antipyretic
- phosphorus pentachloride
- acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- YGSDEFSMJLZEOE-UHFFFAOYSA-N salicylic acid Chemical compound OC(=O)C1=CC=CC=C1O YGSDEFSMJLZEOE-UHFFFAOYSA-N 0.000 title abstract 4
- 239000000730 antalgic agent Substances 0.000 title abstract 2
- 229940121363 anti-inflammatory agent Drugs 0.000 title abstract 2
- 239000002260 anti-inflammatory agent Substances 0.000 title abstract 2
- 230000001754 anti-pyretic effect Effects 0.000 title abstract 2
- 239000002221 antipyretic Substances 0.000 title abstract 2
- 229940125716 antipyretic agent Drugs 0.000 title abstract 2
- FJKROLUGYXJWQN-UHFFFAOYSA-N papa-hydroxy-benzoic acid Natural products OC(=O)C1=CC=C(O)C=C1 FJKROLUGYXJWQN-UHFFFAOYSA-N 0.000 title abstract 2
- UHZYTMXLRWXGPK-UHFFFAOYSA-N phosphorus pentachloride Chemical compound ClP(Cl)(Cl)(Cl)Cl UHZYTMXLRWXGPK-UHFFFAOYSA-N 0.000 title abstract 2
- 229960004889 salicylic acid Drugs 0.000 title abstract 2
- 230000000202 analgesic effect Effects 0.000 title 1
- FFKUDWZICMJVPA-UHFFFAOYSA-N 2-phosphonooxybenzoic acid Chemical compound OC(=O)C1=CC=CC=C1OP(O)(O)=O FFKUDWZICMJVPA-UHFFFAOYSA-N 0.000 abstract 1
- 229940035676 analgesics Drugs 0.000 abstract 1
- 229950010892 fosfosal Drugs 0.000 abstract 1
- 231100001231 less toxic Toxicity 0.000 abstract 1
- 239000003960 organic solvent Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/08—Esters of oxyacids of phosphorus
- C07F9/09—Esters of phosphoric acids
- C07F9/12—Esters of phosphoric acids with hydroxyaryl compounds
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Procedimiento de obtención del ácido 2-fosfonoxibenzoico y sales del mismo, cuyo ácido responde a la fórmula, que consiste esencialmente en tratar en una sola etapa el ácido 2-hidroxibenzoico con pentacloruro de fósforo, para obtener un tricloruro de ácido intermedio que se hidroliza con agua, seguido por precipitación del producto de reacción con un disolvente orgánico.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US70186976A | 1976-07-01 | 1976-07-01 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES460645A1 true ES460645A1 (es) | 1978-05-01 |
Family
ID=24819007
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES460645A Expired ES460645A1 (es) | 1976-07-01 | 1977-07-01 | Procedimiento de obtencion del acido 2-fosfonoxibenzoico y sales del mismo. |
Country Status (2)
| Country | Link |
|---|---|
| DE (1) | DE2641526A1 (es) |
| ES (1) | ES460645A1 (es) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2109893A1 (es) * | 1996-07-26 | 1998-01-16 | Urquima Sa | Procedimiento de preparacion industrial mediante fosforilacion con pentoxido de fosforo. |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1171318B (it) * | 1981-06-19 | 1987-06-10 | Malesci Sas | Composto idrosolubile ad attivita' antinfiammatoria analgesica antipiretica e relativo procedimento di preparazione |
| IT1270996B (it) * | 1994-07-22 | 1997-05-26 | Wilton Licensing Ag | Derivati fosforilati di composti aventi attivita' antiinfiammatoria o analgesica e procedimento per la loro preparazione |
-
1976
- 1976-09-15 DE DE19762641526 patent/DE2641526A1/de not_active Withdrawn
-
1977
- 1977-07-01 ES ES460645A patent/ES460645A1/es not_active Expired
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2109893A1 (es) * | 1996-07-26 | 1998-01-16 | Urquima Sa | Procedimiento de preparacion industrial mediante fosforilacion con pentoxido de fosforo. |
Also Published As
| Publication number | Publication date |
|---|---|
| DE2641526A1 (de) | 1978-01-12 |
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