ES462849A1 - Un procedimiento para la preparacion de nuevos derivados de 3,5-diona-4,4-dimetil-pirrolidina. - Google Patents

Un procedimiento para la preparacion de nuevos derivados de 3,5-diona-4,4-dimetil-pirrolidina.

Info

Publication number
ES462849A1
ES462849A1 ES462849A ES462849A ES462849A1 ES 462849 A1 ES462849 A1 ES 462849A1 ES 462849 A ES462849 A ES 462849A ES 462849 A ES462849 A ES 462849A ES 462849 A1 ES462849 A1 ES 462849A1
Authority
ES
Spain
Prior art keywords
dimethyl
preparation
pyrrolidine
diona
procedure
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES462849A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beecham Group PLC
Original Assignee
Beecham Group PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB43989/75A external-priority patent/GB1560942A/en
Application filed by Beecham Group PLC filed Critical Beecham Group PLC
Publication of ES462849A1 publication Critical patent/ES462849A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • C07D207/273—2-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/36—Oxygen or sulfur atoms
    • C07D207/38—2-Pyrrolones

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Compositions Of Macromolecular Compounds (AREA)

Abstract

Un procedimiento para la preparación de nuevos derivados de 3,5-diona-4,4-dimetil-pirrolidina de fórmula: *(ver fórmula I)*.
ES462849A 1975-10-25 1977-10-01 Un procedimiento para la preparacion de nuevos derivados de 3,5-diona-4,4-dimetil-pirrolidina. Expired ES462849A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB43989/75A GB1560942A (en) 1975-10-25 1975-10-25 10,10,-dimethyl-12-azaprostaglandins
GB2127976 1976-05-22

Publications (1)

Publication Number Publication Date
ES462849A1 true ES462849A1 (es) 1978-06-01

Family

ID=26255242

Family Applications (2)

Application Number Title Priority Date Filing Date
ES452648A Expired ES452648A1 (es) 1975-10-25 1976-10-22 Un procedimiento para la preparacion de nuevos derivados de 3,5-diona-4,4-dimetil-pirrolidina.
ES462849A Expired ES462849A1 (es) 1975-10-25 1977-10-01 Un procedimiento para la preparacion de nuevos derivados de 3,5-diona-4,4-dimetil-pirrolidina.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES452648A Expired ES452648A1 (es) 1975-10-25 1976-10-22 Un procedimiento para la preparacion de nuevos derivados de 3,5-diona-4,4-dimetil-pirrolidina.

Country Status (17)

Country Link
US (1) US4136190A (es)
JP (1) JPS5253856A (es)
AT (1) AT364820B (es)
AU (1) AU506442B2 (es)
CA (1) CA1068716A (es)
DE (1) DE2647968A1 (es)
DK (1) DK479076A (es)
ES (2) ES452648A1 (es)
FI (1) FI762999A7 (es)
FR (1) FR2328465A1 (es)
HU (1) HU174538B (es)
IE (1) IE44299B1 (es)
IL (1) IL50643A (es)
NL (1) NL7611760A (es)
NO (1) NO763566L (es)
NZ (1) NZ182263A (es)
SE (1) SE417091B (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1524818A (en) * 1974-11-29 1978-09-13 Beecham Group Ltd 12-azaprostaglandins
NZ182264A (en) * 1975-10-25 1979-01-11 Beecham Group Ltd 2-carboxyalkyl-1-hydroxyalkyl-pyrrolidin-3,5-dione or-piperidin-3,6-dione derivatives prarmaceutical compostions
US4187312A (en) * 1975-10-25 1980-02-05 Beecham Group Limited 3-Hydroxy-4,4-dimethyl-5-pyrrolidone derivatives
IL58384A0 (en) * 1978-10-14 1980-01-31 Beecham Group Ltd 12-aza analogues of prostcyclin their preparation and pharmaceutical composition containing them
DE3212591A1 (de) * 1982-04-03 1983-10-13 Gödecke AG, 1000 Berlin 2-pyrrolin-3-carbonitril-derivate, verfahren zu deren herstellung und diese enthaltende arzneimittel

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3975399A (en) * 1974-08-06 1976-08-17 E. I. Du Pont De Nemours And Company 1,5-Disubstituted-2-pyrrolidinones, -3-pyrrolin-2-ones, and -4-pyrrolin-2-ones
US4003911A (en) * 1975-09-26 1977-01-18 E. I. Du Pont De Nemours And Company Selected 3-pyrrolidinones and 2,4-pyrrolidindiones

Also Published As

Publication number Publication date
SE7611774L (sv) 1977-04-26
AU506442B2 (en) 1980-01-03
FI762999A7 (es) 1977-04-26
AT364820B (de) 1981-11-25
NL7611760A (nl) 1977-04-27
IL50643A0 (en) 1976-12-31
NO763566L (es) 1977-04-26
ATA788676A (de) 1981-04-15
US4136190A (en) 1979-01-23
DE2647968A1 (de) 1977-05-05
JPS5253856A (en) 1977-04-30
DK479076A (da) 1977-04-26
IE44299L (en) 1977-04-25
ES452648A1 (es) 1978-03-16
CA1068716A (en) 1979-12-25
NZ182263A (en) 1979-01-11
FR2328465B1 (es) 1978-11-17
AU1868776A (en) 1978-04-20
IL50643A (en) 1980-02-29
IE44299B1 (en) 1981-10-07
SE417091B (sv) 1981-02-23
FR2328465A1 (fr) 1977-05-20
HU174538B (hu) 1980-02-28

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