ES469353A1 - Un procedimiento para la preparacion de compuestos derivadosde bencimidazol - Google Patents

Un procedimiento para la preparacion de compuestos derivadosde bencimidazol

Info

Publication number
ES469353A1
ES469353A1 ES469353A ES469353A ES469353A1 ES 469353 A1 ES469353 A1 ES 469353A1 ES 469353 A ES469353 A ES 469353A ES 469353 A ES469353 A ES 469353A ES 469353 A1 ES469353 A1 ES 469353A1
Authority
ES
Spain
Prior art keywords
lower alkyl
hydrogen atom
benzimidazole derivative
formula
cycloalkyl group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES469353A
Other languages
English (en)
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB18438/77A external-priority patent/GB1595316A/en
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of ES469353A1 publication Critical patent/ES469353A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/18—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
    • C07D303/20—Ethers with hydroxy compounds containing no oxirane rings
    • C07D303/22—Ethers with hydroxy compounds containing no oxirane rings with monohydroxy compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D235/26—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D235/28—Sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
ES469353A 1977-05-03 1978-05-02 Un procedimiento para la preparacion de compuestos derivadosde bencimidazol Expired ES469353A1 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB18438/77A GB1595316A (en) 1977-05-03 1977-05-03 4-(3-amino-2-hydroxy-propoxy)-benzimidazole derivatives and pharmaceutical compositions containing them
GB4915677 1977-11-25
GB220878 1978-01-19

Publications (1)

Publication Number Publication Date
ES469353A1 true ES469353A1 (es) 1980-01-01

Family

ID=27254036

Family Applications (1)

Application Number Title Priority Date Filing Date
ES469353A Expired ES469353A1 (es) 1977-05-03 1978-05-02 Un procedimiento para la preparacion de compuestos derivadosde bencimidazol

Country Status (18)

Country Link
JP (1) JPS53135979A (da)
AR (2) AR220335A1 (da)
AU (1) AU3569678A (da)
DE (1) DE2819458A1 (da)
DK (1) DK190378A (da)
ES (1) ES469353A1 (da)
FI (1) FI781349A7 (da)
FR (1) FR2399414A1 (da)
GR (1) GR73669B (da)
IL (1) IL54591A0 (da)
IT (1) IT1096276B (da)
LU (1) LU79591A1 (da)
MC (1) MC1192A1 (da)
NL (1) NL7804794A (da)
NO (1) NO781556L (da)
NZ (1) NZ187066A (da)
PT (1) PT67980A (da)
SE (1) SE7805140L (da)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2801980A1 (de) 1978-01-18 1979-07-19 Boehringer Mannheim Gmbh 4-hydroxy-2-benzimidazolin-thion- derivate, verfahren zu ihrer herstellung sowie diese verbindungen enthaltende arzneimittel
EP0003758A1 (de) * 1978-02-09 1979-09-05 Ciba-Geigy Ag Verätherte Hydroxy-benzodiheterocyclen und ihre Säureadditionssalze, Verfahren zu deren Herstellung und diese enthaltende pharmazeutische Präparate
DE2905877A1 (de) * 1979-02-16 1980-08-28 Boehringer Mannheim Gmbh Neue aminopropanolderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
CH661501A5 (fr) * 1982-01-26 1987-07-31 Oreal Composes derivant du amino-3 propanol-2 utilisables pour la teinture des cheveux, leur procede de preparation, composition de teinture les contenant et procede de teinture de cheveux correspondant.
DE3839743A1 (de) * 1988-11-25 1990-05-31 Hoechst Ag Verfahren zur herstellung von benzimidazolonen
US9784726B2 (en) 2013-01-08 2017-10-10 Atrogi Ab Screening method, a kit, a method of treatment and a compound for use in a method of treatment
GB201714734D0 (en) 2017-09-13 2017-10-25 Atrogi Ab New compounds and uses
GB201714740D0 (en) 2017-09-13 2017-10-25 Atrogi Ab New compounds and uses
GB201714736D0 (en) 2017-09-13 2017-10-25 Atrogi Ab New compounds and uses
GB201714745D0 (en) 2017-09-13 2017-10-25 Atrogi Ab New compounds and uses
GB201903832D0 (en) 2019-03-20 2019-05-01 Atrogi Ab New compounds and methods
GB202205895D0 (en) 2022-04-22 2022-06-08 Atrogi Ab New medical uses

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1058822A (en) * 1963-07-30 1967-02-15 Ici Ltd 3-amino-2-hydroxypropoxy heterocyclic derivatives
GB1363735A (en) * 1970-10-23 1974-08-14 Hoechst Ag Process for the manufacture of benzimidazolones
US4081447A (en) * 1975-04-09 1978-03-28 Abbott Laboratories 5-[2-Hydroxy-3-(3,4-dimethoxy phenethylamino)]-propoxy-3,4-dihydro carbostyril and pharmaceutically acceptable salts thereof
CH624395A5 (da) * 1976-01-08 1981-07-31 Ciba Geigy Ag

Also Published As

Publication number Publication date
JPS53135979A (en) 1978-11-28
IT1096276B (it) 1985-08-26
FR2399414A1 (fr) 1979-03-02
FI781349A7 (fi) 1978-11-04
DE2819458A1 (de) 1978-11-16
PT67980B (da) 1980-05-05
NO781556L (no) 1978-11-06
AR219173A1 (es) 1980-07-31
NL7804794A (nl) 1978-11-07
MC1192A1 (fr) 1979-02-23
SE7805140L (sv) 1978-11-04
NZ187066A (en) 1981-02-11
GR73669B (da) 1984-03-28
AU3569678A (en) 1979-11-08
IL54591A0 (en) 1978-07-31
AR220335A1 (es) 1980-10-31
IT7823000A0 (it) 1978-05-03
PT67980A (en) 1978-06-01
DK190378A (da) 1978-11-04
LU79591A1 (de) 1979-06-13

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