ES471593A1 - Procedimiento para preparar nuevos derivados indolicos - Google Patents

Procedimiento para preparar nuevos derivados indolicos

Info

Publication number
ES471593A1
ES471593A1 ES471593A ES471593A ES471593A1 ES 471593 A1 ES471593 A1 ES 471593A1 ES 471593 A ES471593 A ES 471593A ES 471593 A ES471593 A ES 471593A ES 471593 A1 ES471593 A1 ES 471593A1
Authority
ES
Spain
Prior art keywords
alkyl
hydrogen
alkylamino
procedure
substituted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES471593A
Other languages
English (en)
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz AG filed Critical Sandoz AG
Publication of ES471593A1 publication Critical patent/ES471593A1/es
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C07D209/16Tryptamines
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
ES471593A 1977-07-12 1978-07-10 Procedimiento para preparar nuevos derivados indolicos Expired ES471593A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH858977 1977-07-12
CH300878 1978-03-20

Publications (1)

Publication Number Publication Date
ES471593A1 true ES471593A1 (es) 1979-10-01

Family

ID=25691930

Family Applications (1)

Application Number Title Priority Date Filing Date
ES471593A Expired ES471593A1 (es) 1977-07-12 1978-07-10 Procedimiento para preparar nuevos derivados indolicos

Country Status (14)

Country Link
EP (1) EP0000355B1 (fr)
JP (1) JPS5436259A (fr)
AU (1) AU521641B2 (fr)
CA (1) CA1114381A (fr)
DE (1) DE2861502D1 (fr)
DK (1) DK300978A (fr)
ES (1) ES471593A1 (fr)
FI (1) FI782138A7 (fr)
IE (1) IE47209B1 (fr)
IL (1) IL55116A (fr)
IT (1) IT7850140A0 (fr)
NZ (1) NZ187813A (fr)
PH (1) PH14993A (fr)
PT (1) PT68270A (fr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0003901B1 (fr) * 1978-02-24 1981-08-05 Pfizer Limited 3-(Imidazol-1-ylalkyl)indoles, comme inhibiteurs sélectifs de la thromboxane synthétase, compositions pharmaceutiques les contenant et leurs procédés de préparation
US4634713A (en) * 1982-05-28 1987-01-06 Ciba-Geigy Corporation Antihypertensive 3-(ureidocyclohexyleneamino)propane-1,2-diol derivatives
JPH0283380A (ja) * 1988-09-21 1990-03-23 Kotobuki Seiyaku Kk 新規ジアミン誘導体、抗不整脈剤及びその製法
FR2642422A1 (fr) * 1988-12-22 1990-08-03 Roussel Uclaf Nouvelles polyamines acylees, leur procede de preparation et leur application comme fongicides
US5656642A (en) * 1993-04-07 1997-08-12 Otsuka Pharmaceutical Co., Ltd. Peripheral vasodilating agent containing piperidine derivative as active ingredient
MY142362A (en) 2004-01-29 2010-11-30 Otsuka Pharma Co Ltd Pharmaceutical composition for promoting angiogenesis
US11764679B2 (en) 2020-01-15 2023-09-19 Solaredge Technologies Ltd. Power device
CN116478134B (zh) * 2022-01-17 2025-07-25 上海医药工业研究院有限公司 Ssri/5-ht1a双靶点抗抑郁甲酰哌啶类化合物及其制备方法和应用
CN115433164B (zh) * 2022-09-14 2023-12-12 南京师范大学 烟酰胺衍生物及其制备方法和在抗衰老延长寿命中的应用

Also Published As

Publication number Publication date
JPS5436259A (en) 1979-03-16
PT68270A (en) 1978-08-01
IE781382L (en) 1979-01-12
IE47209B1 (en) 1984-01-11
EP0000355A1 (fr) 1979-01-24
IL55116A0 (en) 1978-09-29
PH14993A (en) 1982-03-22
FI782138A7 (fi) 1979-01-13
CA1114381A (fr) 1981-12-15
DE2861502D1 (en) 1982-02-25
AU3793978A (en) 1980-01-17
NZ187813A (en) 1981-03-16
IL55116A (en) 1982-02-28
IT7850140A0 (it) 1978-07-03
DK300978A (da) 1979-01-13
AU521641B2 (en) 1982-04-22
EP0000355B1 (fr) 1982-01-06

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20001009