ES471896A1 - Procedimiento para preparar particulas conteniendo enzimas - Google Patents

Procedimiento para preparar particulas conteniendo enzimas

Info

Publication number
ES471896A1
ES471896A1 ES471896A ES471896A ES471896A1 ES 471896 A1 ES471896 A1 ES 471896A1 ES 471896 A ES471896 A ES 471896A ES 471896 A ES471896 A ES 471896A ES 471896 A1 ES471896 A1 ES 471896A1
Authority
ES
Spain
Prior art keywords
particles
enzyme
compositions
give
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES471896A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Gist Brocades NV
Original Assignee
Gist Brocades NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gist Brocades NV filed Critical Gist Brocades NV
Publication of ES471896A1 publication Critical patent/ES471896A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16—Organic compounds
    • C11D3/38—Products with no well-defined composition, e.g. natural products
    • C11D3/386—Preparations containing enzymes, e.g. protease or amylase
    • C11D3/38672—Granulated or coated enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/98—Preparation of granular or free-flowing enzyme compositions

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Detergent Compositions (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicinal Preparation (AREA)

Abstract

Procedimiento para preparar partículas conteniendo enzimas que no forman o prácticamente no forman polvo cuando se aplica a las mismas una presión mecánica externa, caracterizado porque comprende mezclar homogéneamente una cantidad de un enzima en forma seca o sustancialmente seca para dar la actividad enzimática deseada en las partículas una vez formadas; con 20 a 60% aproximadamente de un agente cohesivo orgánico hidrófilo, compatible con el enzima; con 10 a 60% aproximadamente de un agente de carga adecuado para usarse en composiciones enzimáticas; y con una pequeña cantidad de agua, si es necesario, suficiente para dar un contenido en humedad en las partículas, una vez formadas, de 5 a 15%; dividir la mezcla obtenida mecánicamente en partículas del tamaño deseado; y revestir las partículas al objeto de evitar la pérdida de humedad.
ES471896A 1977-07-20 1978-07-20 Procedimiento para preparar particulas conteniendo enzimas Expired ES471896A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB30556/77A GB1603640A (en) 1977-07-20 1977-07-20 Enzyme particles

Publications (1)

Publication Number Publication Date
ES471896A1 true ES471896A1 (es) 1979-02-01

Family

ID=10309495

Family Applications (1)

Application Number Title Priority Date Filing Date
ES471896A Expired ES471896A1 (es) 1977-07-20 1978-07-20 Procedimiento para preparar particulas conteniendo enzimas

Country Status (11)

Country Link
US (1) US4242219A (es)
BE (1) BE869132A (es)
CH (1) CH635867A5 (es)
DE (1) DE2831778C3 (es)
ES (1) ES471896A1 (es)
FR (1) FR2399434A1 (es)
GB (1) GB1603640A (es)
IE (1) IE47033B1 (es)
IT (1) IT1160433B (es)
LU (1) LU79988A1 (es)
NL (1) NL175639C (es)

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DE3525648A1 (de) * 1985-07-18 1987-01-29 Bokel Heinz Hermann Dr 1-oxa-2-oxo-2-r-3-aza-5-z-cyclopentanderivate
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US6287841B1 (en) 1988-02-11 2001-09-11 Genencor International, Inc. High alkaline serine protease
US5030378A (en) * 1990-01-02 1991-07-09 The Procter & Gamble Company Liquid detergents containing anionic surfactant, builder and proteolytic enzyme
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BR9306884A (pt) * 1992-08-14 1998-12-08 Solvay Enzymes Gmbh & Co Kg Novos granulados enzimáticos
GB2287947A (en) * 1994-03-19 1995-10-04 Procter & Gamble Detergent composition comprising lactase
US5858946A (en) * 1994-03-19 1999-01-12 Procter & Gamble Company Detergent compositions
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US6500463B1 (en) * 1999-10-01 2002-12-31 General Mills, Inc. Encapsulation of sensitive components into a matrix to obtain discrete shelf-stable particles
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US6468568B1 (en) 2000-06-16 2002-10-22 General Mills, Inc. Oligosaccharide encapsulated mineral and vitamin ingredients
US6558718B1 (en) 2000-06-19 2003-05-06 General Mills, Inc. Nutrient clusters for food products and methods of preparation
US7018821B2 (en) * 2001-06-22 2006-03-28 Genencor International, Inc. Highly impact-resistant granules
ATE450606T1 (de) * 2002-01-16 2009-12-15 Genencor Int Mehrfachsubstituierte proteasevarianten
US7431986B2 (en) * 2002-07-24 2008-10-07 General Mills, Inc. Encapsulation of sensitive components using pre-emulsification
EP1576084B1 (en) * 2002-12-24 2008-04-30 Genencor International, Inc. Mechanically robust plasticized granules
US8088387B2 (en) 2003-10-10 2012-01-03 Immunogen Inc. Method of targeting specific cell populations using cell-binding agent maytansinoid conjugates linked via a non-cleavable linker, said conjugates, and methods of making said conjugates
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DE102004021384A1 (de) * 2004-04-30 2005-11-24 Henkel Kgaa Verfahren zur Herstellung von Granulaten mit verbesserter Lagerstabilität und Abriebfestigkeit
KR101555058B1 (ko) 2005-07-29 2015-09-22 애보트 래버러토리즈 게엠베하 살균된 판크레아틴 분말의 제조방법
US9198871B2 (en) * 2005-08-15 2015-12-01 Abbott Products Gmbh Delayed release pancreatin compositions
US11266607B2 (en) * 2005-08-15 2022-03-08 AbbVie Pharmaceuticals GmbH Process for the manufacture and use of pancreatin micropellet cores
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US20090163398A1 (en) * 2005-11-16 2009-06-25 Kao Corporation Composite particle
US10072256B2 (en) * 2006-05-22 2018-09-11 Abbott Products Gmbh Process for separating and determining the viral load in a pancreatin sample
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Also Published As

Publication number Publication date
IE47033B1 (en) 1983-11-30
NL175639B (nl) 1984-07-02
IE781442L (en) 1979-01-20
IT1160433B (it) 1987-03-11
NL7806728A (nl) 1979-01-23
IT7868719A0 (it) 1978-07-19
FR2399434A1 (fr) 1979-03-02
FR2399434B1 (es) 1982-03-05
GB1603640A (en) 1981-11-25
BE869132A (fr) 1979-01-19
CH635867A5 (de) 1983-04-29
DE2831778B2 (de) 1979-08-16
NL175639C (nl) 1984-12-03
LU79988A1 (es) 1978-12-12
DE2831778C3 (de) 1980-04-24
DE2831778A1 (de) 1979-01-25
US4242219A (en) 1980-12-30

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19990503