ES475533A1 - Un metodo para la preparacion de formas racemicas y optica- mente activas de 2-(4-difenilil)-n-(dimetilamino-alquil)pro-pionamida - Google Patents

Un metodo para la preparacion de formas racemicas y optica- mente activas de 2-(4-difenilil)-n-(dimetilamino-alquil)pro-pionamida

Info

Publication number
ES475533A1
ES475533A1 ES475533A ES475533A ES475533A1 ES 475533 A1 ES475533 A1 ES 475533A1 ES 475533 A ES475533 A ES 475533A ES 475533 A ES475533 A ES 475533A ES 475533 A1 ES475533 A1 ES 475533A1
Authority
ES
Spain
Prior art keywords
novel
manufacture
amide derivative
novel compounds
parenteral
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES475533A
Other languages
English (en)
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
A Menarini SAS
Original Assignee
A Menarini SAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by A Menarini SAS filed Critical A Menarini SAS
Publication of ES475533A1 publication Critical patent/ES475533A1/es
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ES475533A 1977-11-30 1978-11-29 Un metodo para la preparacion de formas racemicas y optica- mente activas de 2-(4-difenilil)-n-(dimetilamino-alquil)pro-pionamida Expired ES475533A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT964377A IT1090782B (it) 1977-11-30 1977-11-30 2 4 bifenilil 2 dietilamino alchil propionamide suoi sali e procedimenti di fabbricazione relativi

Publications (1)

Publication Number Publication Date
ES475533A1 true ES475533A1 (es) 1980-01-16

Family

ID=11132874

Family Applications (1)

Application Number Title Priority Date Filing Date
ES475533A Expired ES475533A1 (es) 1977-11-30 1978-11-29 Un metodo para la preparacion de formas racemicas y optica- mente activas de 2-(4-difenilil)-n-(dimetilamino-alquil)pro-pionamida

Country Status (9)

Country Link
JP (1) JPS5490157A (fr)
BE (1) BE872403A (fr)
CA (1) CA1118446A (fr)
CH (1) CH637370A5 (fr)
DE (1) DE2851416A1 (fr)
ES (1) ES475533A1 (fr)
FR (1) FR2410641A1 (fr)
IT (1) IT1090782B (fr)
NL (1) NL7811698A (fr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITMI20012025A1 (it) * 2001-09-28 2003-03-28 Dompe Spa Sali di ammonio quaternari di omega-amminoalchilammidi di acidi r 2-aril-propionici e composizioni farmaceutiche che li contengono
US20090221703A1 (en) 2006-07-09 2009-09-03 Chongxi Yu High penetration composition and uses thereof
US20090238763A1 (en) 2006-07-09 2009-09-24 Chongxi Yu High penetration compositions and uses thereof
PT2049482E (pt) * 2006-08-08 2016-02-24 Techfields Biochem Co Ltd Profármacos solúveis em água carregados positivamente de ácidos aril- e heteroarilacéticos com velocidade de penetração na pele muito rápida
EP2054384A4 (fr) * 2006-08-15 2010-11-03 Techfields Biochem Co Ltd Promédicaments hydrosolubles chargés positivement contenant des acides aryl- et hétéroarylpropioniques et dotés d'une très grande vitesse de pénétration cutanée
AU2013206218B2 (en) * 2006-08-15 2016-06-30 Techfields Biochem Co. Ltd Positively charged water-soluble prodrugs of aryl- and heteroarylpropionic acids with very fast skin penetration rate
JP2010529101A (ja) 2007-06-04 2010-08-26 テックフィールズ インコーポレイテッド 非常に速い皮膚及び膜浸透速度を有するｎｓａｉａプロドラッグ及びその新規医薬使用
CN108191846B (zh) 2008-12-04 2021-08-20 于崇曦 高穿透性组合物及其应用
JP5940036B2 (ja) * 2013-10-08 2016-06-29 テックフィールズ バイオケム カンパニー リミテッド 非常に速い皮膚透過率を有するアリール−及びヘテロアリールプロピオン酸の正荷電水溶性プロドラッグ
JP6290947B2 (ja) * 2016-02-05 2018-03-07 テックフィールズ バイオケム カンパニー リミテッド 非常に速い皮膚透過率を有するアリール−及びヘテロアリールプロピオン酸の正荷電水溶性プロドラッグ

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1584547A (fr) * 1968-06-05 1969-12-26
FR1593024A (fr) * 1968-09-18 1970-05-25
FR2119846A1 (en) * 1970-12-28 1972-08-11 Choay Sa N,n-diethylaminoethylamide of para isobutyl phenylacetic - acid - antiinflammatory and analgesic
US4145435A (en) * 1976-11-12 1979-03-20 The Upjohn Company 2-aminocycloaliphatic amide compounds

Also Published As

Publication number Publication date
DE2851416C2 (fr) 1989-02-23
JPS631286B2 (fr) 1988-01-12
JPS5490157A (en) 1979-07-17
CH637370A5 (en) 1983-07-29
DE2851416A1 (de) 1979-05-31
IT1090782B (it) 1985-06-26
FR2410641A1 (fr) 1979-06-29
BE872403A (fr) 1979-03-16
FR2410641B1 (fr) 1983-04-15
CA1118446A (fr) 1982-02-16
NL7811698A (nl) 1979-06-01

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19991102