ES484543A1 - Un procedimiento para la preparacion de 2-carboxi-3-azabici-clo (3.1.0)hexano - Google Patents

Un procedimiento para la preparacion de 2-carboxi-3-azabici-clo (3.1.0)hexano

Info

Publication number
ES484543A1
ES484543A1 ES484543A ES484543A ES484543A1 ES 484543 A1 ES484543 A1 ES 484543A1 ES 484543 A ES484543 A ES 484543A ES 484543 A ES484543 A ES 484543A ES 484543 A1 ES484543 A1 ES 484543A1
Authority
ES
Spain
Prior art keywords
hexane
azabicyclo
treating
solution
azabici
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES484543A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SHELL INT RESEARCH
Shell Internationale Research Maatschappij BV
Original Assignee
SHELL INT RESEARCH
Shell Internationale Research Maatschappij BV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SHELL INT RESEARCH, Shell Internationale Research Maatschappij BV filed Critical SHELL INT RESEARCH
Publication of ES484543A1 publication Critical patent/ES484543A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/52—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring condensed with a ring other than six-membered

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Indole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Un procedimiento para la preparación de 2-carboxi-3-azabiciclo [3.1.0] hexano o una sal y/o éster del mismo, caracterizado porque comprende hacer reaccionar 3-azabiciclo [3.1.0] hex-2-eno y/o el trímero del mismo con un bisulfito de metal alcalino para formar su aducto bisulfítico, tratar dicho aducto con un cianuro de metal alcalino, para producir 2-ciano-3-azabiciclo [3.1.0]} hexano, e hidrolizar y/o alcoholizar al menos parte de tal producto.
ES484543A 1978-07-06 1979-09-28 Un procedimiento para la preparacion de 2-carboxi-3-azabici-clo (3.1.0)hexano Expired ES484543A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/922,408 US4225499A (en) 1978-07-06 1978-07-06 Process for preparing 3-azabicyclo(3.1.0)hexane-2-carbonitrile

Publications (1)

Publication Number Publication Date
ES484543A1 true ES484543A1 (es) 1980-05-16

Family

ID=25446988

Family Applications (2)

Application Number Title Priority Date Filing Date
ES482178A Expired ES482178A1 (es) 1978-07-06 1979-07-04 Un procedimiento para la preparacion de 2-ciano-3-azabiciclo-3.1.0-hexano.
ES484543A Expired ES484543A1 (es) 1978-07-06 1979-09-28 Un procedimiento para la preparacion de 2-carboxi-3-azabici-clo (3.1.0)hexano

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES482178A Expired ES482178A1 (es) 1978-07-06 1979-07-04 Un procedimiento para la preparacion de 2-ciano-3-azabiciclo-3.1.0-hexano.

Country Status (14)

Country Link
US (1) US4225499A (es)
EP (1) EP0008813B1 (es)
JP (1) JPS5511588A (es)
AU (1) AU528623B2 (es)
BR (1) BR7904219A (es)
CA (1) CA1116613A (es)
CS (1) CS210691B2 (es)
DD (1) DD144769A5 (es)
DE (1) DE2964138D1 (es)
DK (1) DK241079A (es)
ES (2) ES482178A1 (es)
IL (1) IL57719A0 (es)
PL (1) PL118592B1 (es)
ZA (1) ZA793335B (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1117128A (en) * 1978-10-27 1982-01-26 Derek A. Wood 2-cyano-3-azabicyclo(3.1.0)hexane
US8158807B2 (en) 2006-12-20 2012-04-17 Schering Corporation Process for the preparation of 6,6-dimethyl-3-azabicyclo-[3.1.0]-hexane compounds utilizing bisulfite intermediate
EP2481737A1 (en) 2008-06-24 2012-08-01 Merck Sharp & Dohme Corp. Biocatalytic processes for the preparation of substantially stereomerically pure fused bicyclic proline compounds
CN116987022A (zh) * 2022-04-25 2023-11-03 台州臻挚生物科技有限公司 一种含有氮杂双环-[3.1.0]-己烷-2-酮的化合物的制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2479942A (en) * 1946-01-05 1949-08-23 American Cyanamid Co Alkenylaminoacetonitriles
JPS5247918A (en) * 1975-10-15 1977-04-16 Sumitomo Chem Co Ltd Non-medical fungicides and method of making the same
DK527476A (da) * 1975-12-02 1977-06-03 Sandoz Ag Fremgangsmade til fremstilling af organiske forbindelser
GR72713B (es) * 1976-09-15 1983-12-01 American Cyanamid Co

Also Published As

Publication number Publication date
BR7904219A (pt) 1980-03-18
DK241079A (da) 1980-01-07
EP0008813A1 (en) 1980-03-19
JPS6230186B2 (es) 1987-07-01
DD144769A5 (de) 1980-11-05
IL57719A0 (en) 1979-11-30
ES482178A1 (es) 1980-04-01
PL216849A1 (es) 1980-03-24
PL118592B1 (en) 1981-10-31
AU4863779A (en) 1980-01-10
AU528623B2 (en) 1983-05-05
CS210691B2 (en) 1982-01-29
US4225499A (en) 1980-09-30
JPS5511588A (en) 1980-01-26
ZA793335B (en) 1980-06-25
CA1116613A (en) 1982-01-19
DE2964138D1 (en) 1983-01-05
EP0008813B1 (en) 1982-12-01

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