ES498750A0 - Procedimiento para la preparacion de acidos carboxilicos - Google Patents

Procedimiento para la preparacion de acidos carboxilicos

Info

Publication number: ES498750A0
Authority: ES; Spain
Prior art keywords: methyl; hydrogen; preparation; procedure; carboxyl acids
Prior art date: 1980-01-29
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Granted

Application number

ES498750A

Other languages

English (en)

Other versions

ES8200670A1 (es

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Hoechst AG

Original Assignee

Hoechst AG

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1980-01-29

Filing date

1981-01-23

Publication date

1981-11-01

1981-01-23 Application filed by Hoechst AG filed Critical Hoechst AG

1981-11-01 Publication of ES498750A0 publication Critical patent/ES498750A0/es

1981-11-01 Publication of ES8200670A1 publication Critical patent/ES8200670A1/es

Status Expired legal-status Critical Current

Links

-1 CARBOXYL ACIDS Chemical class 0.000 title abstract 2
239000002253 acid Substances 0.000 title 1
239000001257 hydrogen Substances 0.000 abstract 4
229910052739 hydrogen Inorganic materials 0.000 abstract 4
125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 4
125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 4
CCMLIFHRMDXEBM-UHFFFAOYSA-N 2-phenyl-1,3-thiazol-4-ol Chemical compound OC1=CSC(C=2C=CC=CC=2)=N1 CCMLIFHRMDXEBM-UHFFFAOYSA-N 0.000 abstract 1
WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical compound [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 abstract 1
ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 abstract 1
GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Substances BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 abstract 1
229910052794 bromium Inorganic materials 0.000 abstract 1
125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
229910052801 chlorine Inorganic materials 0.000 abstract 1
239000000460 chlorine Substances 0.000 abstract 1
230000007691 collagen metabolic process Effects 0.000 abstract 1
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/08—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D277/12—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/04—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D277/06—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Obesity (AREA)
Diabetes (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Life Sciences & Earth Sciences (AREA)
Hematology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Thiazole And Isothizaole Compounds (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Plural Heterocyclic Compounds (AREA)

ES498750A 1980-01-29 1981-01-23 Procedimiento para la preparacion de acidos carboxilicos Expired ES8200670A1 (es)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE19803002989 DE3002989A1 (de)	1980-01-29	1980-01-29	Hydroxyphenyl-thiazol, -thiazolin und -thiazolidin-carbonsaeuren, verfahren zu ihrer herstellung und ihre verwendung zur beeinflussung des kollagenstoffwechsels

Publications (2)

Publication Number	Publication Date
ES498750A0 true ES498750A0 (es)	1981-11-01
ES8200670A1 ES8200670A1 (es)	1981-11-01

Family

ID=6093111

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
ES498750A Expired ES8200670A1 (es)	1980-01-29	1981-01-23	Procedimiento para la preparacion de acidos carboxilicos
ES498766A Expired ES8204726A1 (es)	1980-01-29	1981-01-23	Procedimiento para la preparacion de acidos carboxilicos

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
ES498766A Expired ES8204726A1 (es)	1980-01-29	1981-01-23	Procedimiento para la preparacion de acidos carboxilicos

Country Status (7)

Country	Link
US (1)	US4457936A (es)
EP (1)	EP0033151B1 (es)
JP (1)	JPS56120675A (es)
AT (1)	ATE7297T1 (es)
CA (1)	CA1171420A (es)
DE (2)	DE3002989A1 (es)
ES (2)	ES8200670A1 (es)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3002989A1 (de) *	1980-01-29	1981-07-30	Hoechst Ag, 6000 Frankfurt	Hydroxyphenyl-thiazol, -thiazolin und -thiazolidin-carbonsaeuren, verfahren zu ihrer herstellung und ihre verwendung zur beeinflussung des kollagenstoffwechsels
US4935412A (en) *	1983-12-29	1990-06-19	The Research Foundation Of State University Of New York	Non-antibacterial tetracycline compositions possessing anti-collagenolytic properties and methods of preparing and using same
USRE34656E (en) *	1983-12-29	1994-07-05	The Research Foundation Of State University Of New York	Use of tetracycline to enhance bone protein synthesis and/or treatment of bone deficiency
US4666897A (en) *	1983-12-29	1987-05-19	Research Foundation Of State University	Inhibition of mammalian collagenolytic enzymes by tetracyclines
DE3432094A1 (de) *	1984-08-31	1986-03-06	Hoechst Ag, 6230 Frankfurt	Ester der pyridin-2,4- und -2,5- dicarbonsaeure als arzneimittel zur inhibierung der prolin- und lysinhydroxylase
DE3544338A1 (de) *	1985-12-14	1987-06-19	Hoechst Ag	Peptid-derivate mit inhibitorischer wirkung auf hydroxylierende enzyme, verfahren zu ihrer herstellung, diese enthaltende mittel und ihre verwendung
IT1196485B (it) *	1986-07-14	1988-11-16	Zambon Spa	Derivati dell'acido tiazolidin-4-carbossilico ad attivita' farmaceutica
JPS6339868A (ja) *	1986-08-04	1988-02-20	Otsuka Pharmaceut Factory Inc	ジ低級アルキルフエノ−ル誘導体
DE3643012A1 (de) *	1986-12-17	1988-06-30	Hoechst Ag	2,3-disubstituierte isoxazolidine, verfahren zu ihrer herstellung, diese enthaltende mittel und ihre verwendung
DK0513379T3 (da) *	1990-11-30	1996-09-30	Teijin Ltd	2-Arylthiazolderivater og farmaceutisk præparat indeholdende sådanne
US5840739A (en) *	1992-11-16	1998-11-24	University Of Florida Research Foundation, Inc.	Thiazoline acid derivatives
ES2156633T3 (es) *	1996-03-25	2001-07-01	Alcon Lab Inc	Derivados del acido tiazolidina-4-carboxilico como agentes citoprotectores.
EP0878480A1 (en) *	1997-05-14	1998-11-18	H.W. Prof. Dr. Müller	A method for the improvement of neuronal regeneration
US6495539B1 (en)	1998-02-19	2002-12-17	Washington University	B-lactam-like chaperone inhibitors
US6083966A (en) *	1998-08-31	2000-07-04	University Of Florida	Thiazoline acid derivatives
CN1585639A (zh)	1998-09-21	2005-02-23	佛罗里达大学研究基金会	抗疟疾制剂
EP1488791A3 (en) *	1998-09-21	2005-04-06	University Of Florida Research Foundation, Inc.	Antimalarial agents
AU2164300A (en) *	1998-12-04	2000-06-26	N.V. Organon	Substituted thiazoles for treatment of human diseases involving modulators of p-, l- and e- selectin
US7038073B2 (en)	2002-05-15	2006-05-02	Genzyme Corporation	Synthesis of 2-alkyl amino acids
WO2005034949A1 (en)	2003-09-09	2005-04-21	University Of Florida	Desferrithiocin derivatives and their use as iron chelators
WO2005055931A2 (en) *	2003-12-03	2005-06-23	University Of Medicine And Dentistry Of New Jersey	Method of preventing survival of retrovirally cells and of inhibiting formation of infectious retroviruses
SG158168A1 (en)	2004-12-23	2010-01-29	Arena Pharm Inc	5ht2c receptor modulator compositions and methods of use
TR201910900T4 (tr)	2005-04-04	2019-08-21	Univ Florida	Desferritiyokin polieter analogları.
WO2008115433A1 (en)	2007-03-15	2008-09-25	University Of Florida	Desferrithiocin polyether analogues
EP2566854A4 (en) *	2010-05-04	2013-11-06	Shire Llc	DESAZADESFERROTHIOCIN AND DEAZADESFERROTHIOCIN POLYETHER ANALOGS AS METAL CHELATORS
EP3620161A1 (en)	2011-12-16	2020-03-11	University of Florida Research Foundation, Inc.	Uses of 4'-desferrithiocin analogs
AU2014352780A1 (en)	2013-11-22	2016-06-09	University Of Florida Research Foundation, Inc.	Desferrithiocin analogs and uses thereof
KR20170140306A (ko)	2015-04-27	2017-12-20	유니버시티 오브 플로리다 리서치 파운데이션, 인코포레이티드	대사적으로 프로그램화된 금속 킬레이트화제 및 그의 용도

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB584981A (en) *	1945-03-12	1947-01-28	Herbert Clare Carrington	Manufacture of thiazoline derivatives
US3809754A (en) *	1968-12-31	1974-05-07	Medial De Toledo & Cie	Method of treating diseases of the mucous membrane using compounds of a thiazolidine carboxylic acid and pharmaceutical preparations thereof
US3882110A (en) *	1969-06-11	1975-05-06	Roussel Uclaf	Novel 2-alkyl-5-thiazole-carboxylic acid derivatives
IT1050117B (it) *	1969-09-17	1981-03-10	Godo Shusei Kk	Metodo per la sintesi dell acido aeruginoico
FR2062120A5 (es) *	1969-10-10	1971-06-25	Messier Fa
FR2141526B1 (es) *	1971-06-14	1975-05-30	Roussel Uclaf
DE2245560A1 (de) *	1972-09-16	1974-03-21	Basf Ag	Verfahren zur herstellung von 4alkoxycarbonyl-2-thiazolinen
GB1584981A (en) *	1977-01-13	1981-02-18	Davy Instr Ltd	Conveyor weigher
DE3002989A1 (de) *	1980-01-29	1981-07-30	Hoechst Ag, 6000 Frankfurt	Hydroxyphenyl-thiazol, -thiazolin und -thiazolidin-carbonsaeuren, verfahren zu ihrer herstellung und ihre verwendung zur beeinflussung des kollagenstoffwechsels
US4367233A (en) *	1981-10-02	1983-01-04	American Home Products Corporation	Inhibitors of mammalian collagenase

1980
- 1980-01-29 DE DE19803002989 patent/DE3002989A1/de not_active Withdrawn
1981
- 1981-01-23 ES ES498750A patent/ES8200670A1/es not_active Expired
- 1981-01-23 ES ES498766A patent/ES8204726A1/es not_active Expired
- 1981-01-24 AT AT81100532T patent/ATE7297T1/de not_active IP Right Cessation
- 1981-01-24 DE DE8181100532T patent/DE3163339D1/de not_active Expired
- 1981-01-24 EP EP81100532A patent/EP0033151B1/de not_active Expired
- 1981-01-28 CA CA000369496A patent/CA1171420A/en not_active Expired
- 1981-01-29 JP JP1221281A patent/JPS56120675A/ja active Pending
1982
- 1982-04-07 US US06/366,318 patent/US4457936A/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
EP0033151B1 (de)	1984-05-02
CA1171420A (en)	1984-07-24
DE3163339D1 (en)	1984-06-07
US4457936A (en)	1984-07-03
EP0033151A1 (de)	1981-08-05
ES498766A0 (es)	1982-05-01
DE3002989A1 (de)	1981-07-30
ATE7297T1 (de)	1984-05-15
ES8204726A1 (es)	1982-05-01
JPS56120675A (en)	1981-09-22
ES8200670A1 (es)	1981-11-01

Publication	Publication Date	Title
ES498766A0 (es)	1982-05-01	Procedimiento para la preparacion de acidos carboxilicos
DK138982A (da)	1982-09-28	Fremgangsmaade til fremstilling af bispidinderivater
DK65987D0 (da)	1987-02-10	1,4-benzoxazinderivater eller syreadditionssalte deraf, fremgangsmaade til fremstilling af forbindelserne og forbindelsernes anvendelse
ATE75722T1 (de)	1992-05-15	Neue diphenylpropylamin-derivate, ihre herstellung sowie ihre pharmazeutische verwendung.
ES557515A0 (es)	1988-02-16	Procedimiento para la obtencion de derivados del acido piridin-3-carboxilico
DK408083D0 (da)	1983-09-08	Isoquinilinderivater, deres fremstilling og anvendelse
SE8303136L (sv)	1983-12-09	Optiskt aktiva derivat av n-arylerat oxazolidinon-2, specifika och reversibla inhibitorer av monoaminoxydas av typ b, och deras framstellningssett
FI852730A0 (fi)	1985-07-10	(pyrrol-1-yl) -fenyl-dihydropyridazinoner, deras framstaellning och anvaendning.
SE7811455L (sv)	1979-07-02	2-imino-imidazolidin-derivat
ES511097A0 (es)	1983-06-16	"procedimiento para la preparacion de derivados de oxindol".
DK532679A (da)	1980-06-17	Fremgangsmaade til fremstilling af 2-aryl-3,4-diaza-bicyclo (4,1,0)hepten-(2)-on-(5).
ZA83856B (en)	1983-11-30	Thiazaspirane derivatives,processes for their preparation,and medicaments
FI870067A0 (fi)	1987-01-08	Metionin-substituerade 1,4-dihydropyridiner, foerfarande foer deras framstaellning och deras anvaendning.
DE3361181D1 (en)	1985-12-12	Substituted 1-oxo-2-phenyl-2-(2-alkylaminoethyl)-1,2,3,4-tetrahydronaphthalenes, their preparation and use
DE3362130D1 (en)	1986-03-27	7-phenyl-7-phenoxymethyl-hexahydro-1,4-oxazepines, their preparation and use
ES2061722T3 (es)	1994-12-16	Derivados de fenantridina, procedimiento para su obtencion y agentes para la realizacion del procedimiento.
ES517874A0 (es)	1983-12-01	Procedimiento de preparacion de derivados de diaza-3,7a-cicloherta-(j,k)-fluorenos.
ES550218A0 (es)	1987-04-16	Procedimiento para la obtencion de dihidrotiazinas asimetri-cas
FI873483A0 (fi)	1987-08-11	Oxiranpseudooligosackarider, foerfarande foer deras framstaellning, deras anvaendning och farmaceutiska preparat.
DK316682A (da)	1983-01-16	Fremgangsmaade til fremstilling af optisk aktive dipeptider
DK231787A (da)	1987-11-08	3-amino-dihydropyridiner, fremgangsmaade til deres fremstilling og deres anvendelse i laegemidler