ES521952A0 - Un procedimiento para preparar derivados de androsteno. - Google Patents

Un procedimiento para preparar derivados de androsteno.

Info

Publication number: ES521952A0
Authority: ES; Spain
Prior art keywords: androsteno; procedure; preparing derivatives; derivatives; preparing
Prior art date: 1981-08-20
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Granted

Application number

ES521952A

Other languages

English (en)

Other versions

ES8406506A1 (es

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

ER Squibb and Sons LLC

Original Assignee

ER Squibb and Sons LLC

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1981-08-20

Filing date

1983-04-29

Publication date

1984-07-01

1983-04-29 Application filed by ER Squibb and Sons LLC filed Critical ER Squibb and Sons LLC

1984-07-01 Publication of ES521952A0 publication Critical patent/ES521952A0/es

1984-07-01 Publication of ES8406506A1 publication Critical patent/ES8406506A1/es

Status Expired legal-status Critical Current

Links

MSEZLHAVPJYYIQ-VMXHOPILSA-N (8s,9s,10r,13s,14s)-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one Chemical class C1CC2=CC(=O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CCC[C@@]1(C)CC2 MSEZLHAVPJYYIQ-VMXHOPILSA-N 0.000 abstract 1
125000000217 alkyl group Chemical group 0.000 abstract 1
230000003110 anti-inflammatory effect Effects 0.000 abstract 1
125000003118 aryl group Chemical group 0.000 abstract 1
125000000753 cycloalkyl group Chemical group 0.000 abstract 1
125000001424 substituent group Chemical group 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
- C07J31/003—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring the S atom directly linked to a ring carbon atom of the cyclopenta(a)hydrophenanthrene skeleton
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0003—Androstane derivatives
- C07J1/0011—Androstane derivatives substituted in position 17 by a keto group

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Pulmonology (AREA)
Immunology (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Dermatology (AREA)
Steroid Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Cosmetics (AREA)
Inorganic Compounds Of Heavy Metals (AREA)

ES521952A 1981-08-20 1983-04-29 Un procedimiento para preparar derivados de androsteno. Expired ES8406506A1 (es)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US06/294,680 US4361559A (en)	1981-08-20	1981-08-20	Antiinflammatory 17,17-bis (substituted thio) androstenes

Publications (2)

Publication Number	Publication Date
ES521952A0 true ES521952A0 (es)	1984-07-01
ES8406506A1 ES8406506A1 (es)	1984-07-01

Family

ID=23134474

Family Applications (3)

Application Number	Title	Priority Date	Filing Date
ES515110A Expired ES8308336A1 (es)	1981-08-20	1982-08-19	Un procedimiento para preparar compuestos de 3-cetoandroste-no.
ES521951A Granted ES521951A0 (es)	1981-08-20	1983-04-29	Un procedimiento para preparar derivados de androsteno.
ES521952A Expired ES8406506A1 (es)	1981-08-20	1983-04-29	Un procedimiento para preparar derivados de androsteno.

Family Applications Before (2)

Application Number	Title	Priority Date	Filing Date
ES515110A Expired ES8308336A1 (es)	1981-08-20	1982-08-19	Un procedimiento para preparar compuestos de 3-cetoandroste-no.
ES521951A Granted ES521951A0 (es)	1981-08-20	1983-04-29	Un procedimiento para preparar derivados de androsteno.

Country Status (24)

Country	Link
US (1)	US4361559A (es)
EP (1)	EP0073026B1 (es)
JP (1)	JPS5841900A (es)
KR (1)	KR890000678B1 (es)
AT (1)	ATE18671T1 (es)
AU (1)	AU564228B2 (es)
CA (1)	CA1213270A (es)
CS (1)	CS235959B2 (es)
DD (3)	DD211567A5 (es)
DE (1)	DE3269987D1 (es)
DK (1)	DK165838C (es)
ES (3)	ES8308336A1 (es)
FI (1)	FI78916C (es)
GR (1)	GR76251B (es)
HU (1)	HU187783B (es)
IE (1)	IE53732B1 (es)
IL (1)	IL66564A (es)
NO (1)	NO159601C (es)
NZ (1)	NZ201343A (es)
PH (2)	PH18594A (es)
PL (2)	PL244113A1 (es)
PT (1)	PT75442B (es)
SU (1)	SU1189353A3 (es)
ZA (1)	ZA825260B (es)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4447363A (en) *	1982-07-07	1984-05-08	E. R. Squibb & Sons, Inc.	Androstene-17-dithioketals
US4435326A (en) *	1982-09-09	1984-03-06	E. R. Squibb & Sons, Inc.	Intermediates useful in the preparation of 17,17-bis(substituted thio)androstenes
US4420428A (en) *	1982-12-27	1983-12-13	E. R. Squibb & Sons, Inc.	16-Ketoandrostene-17-dithioketals
US4427592A (en) *	1983-01-31	1984-01-24	E. R. Squibb & Sons, Inc.	Androstene-17-dithioketals
US4481144A (en) *	1984-02-03	1984-11-06	E. R. Squibb & Sons, Inc.	17-Substituted thia-17-alkyl(or alkenyl or alkynyl)androstenes
US4499021A (en) *	1984-04-12	1985-02-12	E. R. Squibb & Sons, Inc.	17β(Substituted thio)-16-ketoandrostene-17α..-carboxylic acid derivatives
US4529548A (en) *	1984-05-07	1985-07-16	E. R. Squibb & Sons, Inc.	17β-(substituted thio)androstenes
US4528138A (en) *	1984-06-20	1985-07-09	E. R. Squibb & Sons, Inc.	16-Keto-17-substituted thia-17-alkyl(or alkenyl or alkynyl) androstenes
US4529547A (en) *	1984-06-20	1985-07-16	E.R. Squibb & Sons, Inc.	17-(substituted thio)-17-(substituted dithio)androstenes
US4891367A (en) *	1987-04-22	1990-01-02	Merrell Dow Pharmaceuticals Inc.	17β-(cyclopropyloxy)androst-5-en-3β-ol and related compounds useful as C17-20 lyase inhibitors
US4868168A (en) *	1987-11-13	1989-09-19	E. R. Squibb & Sons, Inc.	Steroid ointment formulation
US4868169A (en) *	1987-11-13	1989-09-19	E. R. Squibb & Sons, Inc.	Steroid cream formulation
US5016635A (en) *	1988-11-29	1991-05-21	Sigmedics, Inc. Of Delaware	Control of FNS via pattern variations of response EMG
US4883792A (en) *	1989-01-17	1989-11-28	Peter Timmins	Steroid cream formulation
GB9103824D0 (en) *	1991-02-23	1991-04-10	Fisons Ag	Formulation
IE922301A1 (en) *	1991-07-25	1993-01-27	Squibb & Sons Inc	Selective thioketalization process, process for preparing¹thioenol ethers from thioketals, and process for the¹preparation of thioketals
DE4235220A1 (de) *	1992-10-13	1994-06-16	Schering Ag	Gestagen wirksame 19,11ß-überbrückte 4-Estrene
DK0675897T3 (da) *	1992-12-24	1998-01-26	Rhone Poulenc Rorer Ltd	Nye steroider
US5344651A (en) *	1993-07-23	1994-09-06	The Procter & Gamble Company	Cyproterone acetate thioacetate
US5439901A (en) *	1993-07-23	1995-08-08	The Procter & Gamble Company	Cyproterone thiopivalate

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US2840577A (en) *	1956-12-21	1958-06-24	Searle & Co	17-thio derivatives of estratrien-3-ol and of estratetraen-3-ol
US2949477A (en) *	1959-03-04	1960-08-16	Searle & Co	1, 3, 17-triacetoxyestra-1, 3, 5(10), 16-tetraene and congeners
US4094840A (en) *	1977-05-12	1978-06-13	E. R. Squibb & Sons, Inc.	17-Alkylthio (and arylthio) androsteno[16α,17α-b]benzodioxin-3-ones
US4091036A (en) *	1977-05-12	1978-05-23	E. R. Squibb & Sons, Inc.	17-Alkylthio (and arylthio)-1',2',3',4'-tetrahydroandrosteno [16 α, 17 α-b]naphthalenes and derivatives
US4133811A (en) *	1978-02-17	1979-01-09	E. R. Squibb & Sons, Inc.	13-Alkylthio (and arylthio)-11,17-epoxy-17-methyl-18-norandrostenes
US4146538A (en) *	1978-02-27	1979-03-27	E. R. Squibb & Sons, Inc.	17-Alkylthio (and arylthio) androsteno[17α,16α-b]benzopyran-3-ones and [16α,17α]naphthopyran-3-ones

1981
- 1981-08-20 US US06/294,680 patent/US4361559A/en not_active Expired - Lifetime
1982
- 1982-07-19 CA CA000407557A patent/CA1213270A/en not_active Expired
- 1982-07-21 NZ NZ201343A patent/NZ201343A/en unknown
- 1982-07-22 AU AU86318/82A patent/AU564228B2/en not_active Ceased
- 1982-07-22 ZA ZA825260A patent/ZA825260B/xx unknown
- 1982-08-10 PH PH27702A patent/PH18594A/en unknown
- 1982-08-12 IE IE1951/82A patent/IE53732B1/en not_active IP Right Cessation
- 1982-08-12 GR GR69029A patent/GR76251B/el unknown
- 1982-08-17 PL PL24411382A patent/PL244113A1/xx unknown
- 1982-08-17 PL PL1982237936A patent/PL141303B1/pl unknown
- 1982-08-18 IL IL66564A patent/IL66564A/xx not_active IP Right Cessation
- 1982-08-18 HU HU822683A patent/HU187783B/hu not_active IP Right Cessation
- 1982-08-19 SU SU823480340A patent/SU1189353A3/ru active
- 1982-08-19 DE DE8282107589T patent/DE3269987D1/de not_active Expired
- 1982-08-19 KR KR8203735A patent/KR890000678B1/ko not_active Expired
- 1982-08-19 PT PT75442A patent/PT75442B/pt not_active IP Right Cessation
- 1982-08-19 JP JP57144576A patent/JPS5841900A/ja active Granted
- 1982-08-19 AT AT82107589T patent/ATE18671T1/de not_active IP Right Cessation
- 1982-08-19 ES ES515110A patent/ES8308336A1/es not_active Expired
- 1982-08-19 DK DK372982A patent/DK165838C/da not_active IP Right Cessation
- 1982-08-19 FI FI822890A patent/FI78916C/fi not_active IP Right Cessation
- 1982-08-19 CS CS826085A patent/CS235959B2/cs unknown
- 1982-08-19 NO NO822823A patent/NO159601C/no unknown
- 1982-08-19 EP EP82107589A patent/EP0073026B1/en not_active Expired
- 1982-08-20 DD DD82242677A patent/DD211567A5/de not_active IP Right Cessation
- 1982-08-20 DD DD82257403A patent/DD215556A5/de not_active IP Right Cessation
- 1982-08-20 DD DD82257409A patent/DD215086A5/de not_active IP Right Cessation
1983
- 1983-04-29 ES ES521951A patent/ES521951A0/es active Granted
- 1983-04-29 ES ES521952A patent/ES8406506A1/es not_active Expired
1984
- 1984-06-29 PH PH30900A patent/PH19857A/en unknown

Also Published As

Publication number	Publication date
PL237936A1 (en)	1984-02-13
AU8631882A (en)	1983-02-24
FI822890L (fi)	1983-02-21
GR76251B (es)	1984-08-04
SU1189353A3 (ru)	1985-10-30
US4361559A (en)	1982-11-30
DD211567A5 (de)	1984-07-18
PT75442B (en)	1985-01-04
PT75442A (en)	1982-09-01
ATE18671T1 (de)	1986-04-15
IE821951L (en)	1983-02-20
PH18594A (en)	1985-08-12
PH19857A (en)	1986-07-22
HU187783B (en)	1986-02-28
DK165838B (da)	1993-01-25
ES8406505A1 (es)	1984-07-01
FI78916C (fi)	1989-10-10
EP0073026A1 (en)	1983-03-02
IL66564A0 (en)	1982-12-31
CA1213270A (en)	1986-10-28
DD215556A5 (de)	1984-11-14
ZA825260B (en)	1983-05-25
IL66564A (en)	1986-03-31
JPH035400B2 (es)	1991-01-25
KR890000678B1 (ko)	1989-03-24
NO159601C (no)	1989-01-18
IE53732B1 (en)	1989-02-01
ES515110A0 (es)	1983-08-16
NO159601B (no)	1988-10-10
KR840001183A (ko)	1984-03-28
ES521951A0 (es)	1984-07-01
ES8406506A1 (es)	1984-07-01
FI822890A0 (fi)	1982-08-19
EP0073026B1 (en)	1986-03-19
CS235959B2 (en)	1985-05-15
NO822823L (no)	1983-02-21
DK165838C (da)	1993-06-21
DE3269987D1 (en)	1986-04-24
PL141303B1 (en)	1987-07-31
NZ201343A (en)	1985-08-16
PL244113A1 (en)	1984-05-21
ES8308336A1 (es)	1983-08-16
AU564228B2 (en)	1987-08-06
DK372982A (da)	1983-02-21
JPS5841900A (ja)	1983-03-11
DD215086A5 (de)	1984-10-31
FI78916B (fi)	1989-06-30

Legal Events

Date	Code	Title	Description
2000-04-01	FD1A	Patent lapsed	Effective date: 20000201

Publication	Publication Date	Title
ES521951A0 (es)	1984-07-01	Un procedimiento para preparar derivados de androsteno.
ES497517A0 (es)	1982-04-16	Procedimiento de preparacion de nuevos iminoacidos y de sus derivados.
ES502827A0 (es)	1982-11-01	Procedimiento de preparar acidos hidroxicarboxilicos y sus derivados.
ES522037A0 (es)	1985-06-01	Procedimiento para preparar derivados de piperazina.
ES488535A0 (es)	1981-05-16	Procedimiento para preparar derivados de di fosfonatos.
ES517332A0 (es)	1984-04-16	Procedimiento para preparar derivados de feniltiadiazinona.
NO800931L (no)	1980-10-03	Fremgangsmaate for fremstilling av merkapto-acyldipeptider
ES541707A0 (es)	1985-12-01	Procedimiento para la preparacion de derivados de tiazolidina.
AR222635A1 (es)	1981-06-15	Procedimiento para la preparacion de derivados de fenilpiperazina
ES530574A0 (es)	1985-12-16	Procedimiento para preparar derivados de pirazol 1,5-a-piridina
FI801023A7 (fi)	1981-01-01	Bentsotiatsolijohdannaisten valmistusmenetelmä.
ES509744A0 (es)	1983-06-16	Procedimiento para preparar derivados sustituidos de tetrahidropirimidinona.
ES515767A0 (es)	1983-11-01	Procedimiento para preparar derivados de indano.
ES515568A0 (es)	1983-10-16	Procedimiento para preparar derivados de fenantreno.
AR231975A1 (es)	1985-04-30	Procedimiento para preparar derivados de 2-aminoalquil-2-piridilamidas
NL7704298A (nl)	1977-11-30	Werkwijze ter bereiding van p- en q-derivaten van rifamycine.
NL7812132A (nl)	1979-07-03	5.6-dihydroprostacyclinederivaten en werkwijzen ter bereiding ervan.
ES541706A0 (es)	1985-12-01	Procedimiento para la preparacion de derivados de tiazolidina.
ES504681A0 (es)	1982-12-01	Procedimiento para preparar derivados de 11- hidroxi-13 oxa-prostaglandina.
MX159206A (es)	1989-05-02	Procedimiento para preparar derivados de 20,21 dinoreburnamenina
ES513256A0 (es)	1983-07-01	Procedimiento para preparar derivados de cefalosporina.
ES542457A0 (es)	1985-12-16	Procedimiento para preparar derivados de pirazolpiridina.
ES509419A0 (es)	1983-07-01	Procedimiento de preparar nuevos derivados de aprovincaminol.
ES495828A0 (es)	1981-12-01	Procedimiento para preparar derivados de s-fenilseleno-bencimidazol.
ES529614A0 (es)	1985-08-01	Procedimiento de preparar 2-trifluometil-4, 6-dinitrofenol y sus derivados