ES534695A0 - Un procedimiento para preparar ester 1-acetoxietilico de cefuroxima cristalino, muy puro - Google Patents

Un procedimiento para preparar ester 1-acetoxietilico de cefuroxima cristalino, muy puro

Info

Publication number: ES534695A0
Authority: ES; Spain
Prior art keywords: cefuroxyme; acetoxyethylene; ester; prepare; procedure
Prior art date: 1983-07-29
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Granted

Application number

ES534695A

Other languages

English (en)

Spanish (es)

Other versions

ES8601869A1 (es

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Glaxo Group Ltd

Original Assignee

Glaxo Group Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1983-07-29

Filing date

1984-07-27

Publication date

1985-11-01

1984-07-27 Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd

1985-11-01 Publication of ES8601869A1 publication Critical patent/ES8601869A1/es

1985-11-01 Publication of ES534695A0 publication Critical patent/ES534695A0/es

Status Granted legal-status Critical Current

Links

XTXRWKRVRITETP-UHFFFAOYSA-N Vinyl acetate Chemical compound CC(=O)OC=C XTXRWKRVRITETP-UHFFFAOYSA-N 0.000 title 1
150000002148 esters Chemical class 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
- C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
- C07D501/38—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof
- C07D501/46—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof with the 7-amino radical acylated by carboxylic acids containing hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
- C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
- C07D501/26—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group
- C07D501/34—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group with the 7-amino radical acylated by carboxylic acids containing hetero rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Communicable Diseases (AREA)
Pharmacology & Pharmacy (AREA)
Oncology (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Cephalosporin Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

ES534695A 1983-07-29 1984-07-27 Un procedimiento para preparar ester 1-acetoxietilico de cefuroxima cristalino, muy puro Granted ES534695A0 (es)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB838320521A GB8320521D0 (en)	1983-07-29	1983-07-29	Chemical process

Publications (2)

Publication Number	Publication Date
ES8601869A1 ES8601869A1 (es)	1985-11-01
ES534695A0 true ES534695A0 (es)	1985-11-01

Family

ID=10546505

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ES534695A Granted ES534695A0 (es)	1983-07-29	1984-07-27	Un procedimiento para preparar ester 1-acetoxietilico de cefuroxima cristalino, muy puro

Country Status (21)

Country	Link
JP (1)	JPH0613526B2 (de)
KR (1)	KR910008377B1 (de)
AT (1)	AT392470B (de)
AU (2)	AU582121B2 (de)
BE (1)	BE900241A (de)
CA (1)	CA1265511A (de)
CH (1)	CH662121A5 (de)
DE (1)	DE3427828A1 (de)
DK (1)	DK165505C (de)
ES (1)	ES534695A0 (de)
FI (1)	FI76808C (de)
FR (1)	FR2549837B1 (de)
GB (2)	GB8320521D0 (de)
IE (1)	IE57726B1 (de)
IL (1)	IL72536A (de)
NL (1)	NL8402372A (de)
NO (1)	NO167292C (de)
NZ (1)	NZ209046A (de)
PT (1)	PT78985B (de)
SE (1)	SE463263B (de)
ZA (1)	ZA845830B (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB8400024D0 (en) *	1984-01-03	1984-02-08	Glaxo Group Ltd	Cephalosporin antibiotics
GB8524001D0 (en) *	1985-09-30	1985-11-06	Glaxo Group Ltd	Pharmaceutical composition
US5063224A (en) *	1990-07-09	1991-11-05	Eli Lilly And Company	R-cefuroxime axetil
IT1277426B1 (it) *	1995-08-03	1997-11-10	Acs Dobfar Spa	Forma cristallina biodisponibile del cefuroxima axetil
CN1111537C (zh) *	1997-05-15	2003-06-18	第一制糖株式会社	高纯晶形头孢呋辛1－乙酰氧乙酯的制备方法
KR100228264B1 (ko) *	1997-08-02	1999-11-01	김선진	결정형 세푸록심 악세틸의 제조방법
CA2209868C (en) *	1997-08-15	2001-08-14	Bernard Charles Sherman	Pharmaceutical compositions comprising cefuroxime axetil
IN186539B (de) *	1997-09-29	2001-09-29	Ranbaxy Lab Ltd
EP0937727B1 (de) *	1998-02-20	2002-01-30	Fako Ilaclari A.S.	Verfahren zur Herstellung vom löslichen kristallinen Cefuroxim axetil
IN190849B (de)	2000-07-17	2003-08-23	Ranbaxy Lab Ltd
AT411996B (de)	2000-09-11	2004-08-26	Sandoz Ag	Verfahren zur herstellung von cefuroxim in der form seines n-butylammoniumsalzes
ITMI20011763A1 (it) *	2001-08-10	2003-02-10	Antibioticos Spa	Processo di preparazione di cefuroxime axelite ad elevata purezza
ITMI20011925A1 (it) *	2001-09-14	2003-03-14	Antibioticos Spa	Metodo applicabile su scala industriale per la preparazione di cefuroxime axetile cristallino
TWI328006B (en) *	2003-12-26	2010-08-01	Nissan Chemical Ind Ltd	Crystal form of quinoline compound and process for its production
CN100448879C (zh) *	2004-07-22	2009-01-07	北京化工大学	一种无定型头孢呋辛酯的制备方法
DE102005019458A1 (de) *	2005-04-25	2006-10-26	Grünenthal GmbH	Darreichungsform mit verbesserter Freisetzung von Cefuroximaxetil
CN118561870A (zh) *	2024-05-15	2024-08-30	广东立国制药有限公司	一种制备头孢呋辛酸的方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1571683A (en) *	1976-02-16	1980-07-16	Glaxo Operations Ltd	Ester derivatives of cefuroxime
CA1094545A (en) *	1976-02-16	1981-01-27	Michael Gregson	Cephalosporin antibiotics
GB1598568A (en) *	1977-04-19	1981-09-23	Glaxo Lab Ltd	Esters of(6r,7r)-3-carbamoyloxymethyl-7-((z)-2-(fur-2-yl)-2-methoxyiminoacetamido)-ceph-3-em-4-carboxylic acid
JPS577485A (en) *	1980-06-13	1982-01-14	Takeda Chem Ind Ltd	Cephalosporin
YU44680B (en) *	1982-07-30	1990-12-31	Glaxo Lab Ltd	Process for obtaining very pure amorphous form of cephuroxim axetile
GB8400024D0 (en) *	1984-01-03	1984-02-08	Glaxo Group Ltd	Cephalosporin antibiotics

1983
- 1983-07-29 GB GB838320521A patent/GB8320521D0/en active Pending
1984
- 1984-07-27 IE IE1938/84A patent/IE57726B1/en not_active IP Right Cessation
- 1984-07-27 PT PT78985A patent/PT78985B/pt unknown
- 1984-07-27 FR FR8412011A patent/FR2549837B1/fr not_active Expired
- 1984-07-27 JP JP59155694A patent/JPH0613526B2/ja not_active Expired - Lifetime
- 1984-07-27 AT AT2444/84A patent/AT392470B/de not_active IP Right Cessation
- 1984-07-27 DK DK366684A patent/DK165505C/da not_active IP Right Cessation
- 1984-07-27 DE DE19843427828 patent/DE3427828A1/de not_active Ceased
- 1984-07-27 ZA ZA845830A patent/ZA845830B/xx unknown
- 1984-07-27 KR KR1019840004465A patent/KR910008377B1/ko not_active Expired
- 1984-07-27 SE SE8403897A patent/SE463263B/sv not_active IP Right Cessation
- 1984-07-27 AU AU31256/84A patent/AU582121B2/en not_active Ceased
- 1984-07-27 ES ES534695A patent/ES534695A0/es active Granted
- 1984-07-27 FI FI843011A patent/FI76808C/fi not_active IP Right Cessation
- 1984-07-27 CA CA000459929A patent/CA1265511A/en not_active Expired - Fee Related
- 1984-07-27 NO NO843055A patent/NO167292C/no not_active IP Right Cessation
- 1984-07-27 GB GB08419202A patent/GB2145409B/en not_active Expired
- 1984-07-27 CH CH3672/84A patent/CH662121A5/de not_active IP Right Cessation
- 1984-07-27 BE BE0/213398A patent/BE900241A/fr not_active IP Right Cessation
- 1984-07-27 NL NL8402372A patent/NL8402372A/nl not_active Application Discontinuation
- 1984-07-29 IL IL72536A patent/IL72536A/xx not_active IP Right Cessation
- 1984-07-30 NZ NZ209046A patent/NZ209046A/en unknown
1989
- 1989-06-16 AU AU36601/89A patent/AU634965B2/en not_active Ceased

Also Published As

Publication number	Publication date
DK165505B (da)	1992-12-07
FR2549837B1 (fr)	1986-12-26
ATA244484A (de)	1990-09-15
JPS6075484A (ja)	1985-04-27
SE8403897L (sv)	1985-01-30
IL72536A (en)	1988-01-31
FI76808B (fi)	1988-08-31
DE3427828A1 (de)	1985-02-14
FI843011L (fi)	1985-01-30
FI843011A0 (fi)	1984-07-27
NZ209046A (en)	1988-02-29
PT78985B (en)	1986-10-23
NL8402372A (nl)	1985-02-18
KR910008377B1 (ko)	1991-10-12
ES8601869A1 (es)	1985-11-01
KR850001221A (ko)	1985-03-16
NO843055L (no)	1985-01-30
AU582121B2 (en)	1989-03-16
CH662121A5 (de)	1987-09-15
DK366684D0 (da)	1984-07-27
PT78985A (en)	1984-08-01
FR2549837A1 (fr)	1985-02-01
AT392470B (de)	1991-04-10
FI76808C (fi)	1988-12-12
GB2145409A (en)	1985-03-27
SE463263B (sv)	1990-10-29
AU3660189A (en)	1989-10-05
AU3125684A (en)	1985-01-31
GB2145409B (en)	1987-02-18
NO167292B (no)	1991-07-15
GB8419202D0 (en)	1984-08-30
SE8403897D0 (sv)	1984-07-27
BE900241A (fr)	1985-01-28
IL72536A0 (en)	1984-11-30
NO167292C (no)	1991-10-23
DK366684A (da)	1985-01-30
IE841938L (en)	1985-01-29
IE57726B1 (en)	1993-03-24
GB8320521D0 (en)	1983-09-01
DK165505C (da)	1993-04-19
JPH0613526B2 (ja)	1994-02-23
ZA845830B (en)	1986-03-26
CA1265511A (en)	1990-02-06
AU634965B2 (en)	1993-03-11

Publication	Publication Date	Title
ES534695A0 (es)	1985-11-01	Un procedimiento para preparar ester 1-acetoxietilico de cefuroxima cristalino, muy puro
ES544852A0 (es)	1987-04-01	Un procedimiento para la preparacion de derivados sustituidos ester benzoato de 3-hidroximorfinanos.
ES554044A0 (es)	1988-02-16	Procedimiento para preparar un derivado de ciclohexano hidroxibromado
ES548672A0 (es)	1986-12-01	Un procedimiento para la preparacion de un derivado de dihi-dropiridina
ES545756A0 (es)	1986-07-16	Un procedimiento para la preparacion de un derivado de acido6-fluor-1,4-dihidro-4-oxo-7-piperazinilquinolin sustituido-3-carboxilico
FR2574135B1 (fr)	1988-01-22	Cheville a expansion par cone
ES533474A0 (es)	1986-04-01	Procedimiento para modificar un elemento quirurgico estructural
ES540003A0 (es)	1986-09-01	Un procedimiento para preparar un derivado de octahidrobenzo(f) quinoleina
ES543646A0 (es)	1986-05-01	Un procedimiento para la preparacion de derivados esteroida-les
ES534509A0 (es)	1985-09-01	Un procedimiento para la preparacion de acidos fenilquinolin-carboxilicos.
ES532859A0 (es)	1985-12-01	Un procedimiento para producir fenilalanina
ES534607A0 (es)	1985-10-01	Un procedimiento para la preparacion de un derivado de poliol-eter.
ES535981A0 (es)	1986-01-16	Un procedimiento para la preparacion de derivados de benzofurano
ES522597A0 (es)	1984-08-01	Un procedimiento para la produccion de diesteres de acidos sulfosuccinicos
ES541505A0 (es)	1986-04-16	Un procedimiento para la preparacion de monohidrato de bis- hidrobromuro de ceftazidima cristalino
DE3482255D1 (de)	1990-06-21	Kristallines silicophosphoaluminat.
ES531343A0 (es)	1985-07-16	Un procedimiento para producir zincosilicatos cristalinos porosos
DK606384D0 (da)	1984-12-18	Fremgangsmaade til fremstilling af krystallinske silicophosphoaluminater
ES527237A0 (es)	1985-04-16	Un procedimiento para producir derivados de tiazol
ES540839A0 (es)	1986-05-16	Un procedimiento para producir un derivado de ester de cefa-losporina
ES523288A0 (es)	1984-10-01	Procedimiento para preparar un derivado de pirazolpiridina.
ES535392A0 (es)	1985-12-01	Un procedimiento para la preparacion de derivados de imidazobenzodiacepina
ES546645A0 (es)	1987-01-01	Procedimiento para preparar un pseudooligosacarido
ES531498A0 (es)	1985-06-16	Un procedimiento para la preparacion de derivados de pirimidinatriona
ES534252A0 (es)	1986-07-16	Procedimiento de preparar un dentifrico antiplacas, estable