ES546884A0 - Un procedimiento para preparar un derivado de 7-(2-(dialqui-lamino)-etil)-4-hidroxi-1,3-bencimidazol-2-ona - Google Patents

Un procedimiento para preparar un derivado de 7-(2-(dialqui-lamino)-etil)-4-hidroxi-1,3-bencimidazol-2-ona

Info

Publication number: ES546884A0
Authority: ES; Spain
Prior art keywords: dialqui; bencimidazole; hidroxi; etil; lamino
Prior art date: 1984-09-12
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Granted

Application number

ES546884A

Other languages

English (en)

Other versions

ES8605491A1 (es

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

SmithKline Beecham Corp

Original Assignee

SmithKline Beecham Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1984-09-12

Filing date

1985-09-11

Publication date

1986-03-16

1985-09-11 Application filed by SmithKline Beecham Corp filed Critical SmithKline Beecham Corp

1986-03-16 Publication of ES546884A0 publication Critical patent/ES546884A0/es

1986-03-16 Publication of ES8605491A1 publication Critical patent/ES8605491A1/es

Status Expired legal-status Critical Current

Links

238000000034 method Methods 0.000 title abstract 3
150000001875 compounds Chemical class 0.000 abstract 2
-1 methoxyphenethyl Chemical group 0.000 abstract 2
125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 1
125000000094 2-phenylethyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])* 0.000 abstract 1
230000003276 anti-hypertensive effect Effects 0.000 abstract 1
125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
229940052760 dopamine agonists Drugs 0.000 abstract 1
239000003136 dopamine receptor stimulating agent Substances 0.000 abstract 1
229910052739 hydrogen Inorganic materials 0.000 abstract 1
239000001257 hydrogen Substances 0.000 abstract 1
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D235/26—Oxygen atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Cosmetics (AREA)
Detergent Compositions (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Plural Heterocyclic Compounds (AREA)

ES546884A 1984-09-12 1985-09-11 Un procedimiento para preparar un derivado de 7-(2-(dialqui-lamino)-etil)-4-hidroxi-1,3-bencimidazol-2-ona Expired ES8605491A1 (es)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US06/649,465 US4554287A (en)	1984-09-12	1984-09-12	Antihypertensive 7-[2-(dialkylamino)ethyl]-4-hydroxy-1,3-benzimidazol-2-ones

Publications (2)

Publication Number	Publication Date
ES546884A0 true ES546884A0 (es)	1986-03-16
ES8605491A1 ES8605491A1 (es)	1986-03-16

Family

ID=24604906

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ES546884A Expired ES8605491A1 (es)	1984-09-12	1985-09-11	Un procedimiento para preparar un derivado de 7-(2-(dialqui-lamino)-etil)-4-hidroxi-1,3-bencimidazol-2-ona

Country Status (12)

Country	Link
US (1)	US4554287A (es)
EP (1)	EP0175525B1 (es)
JP (1)	JPS6168473A (es)
AT (1)	ATE53025T1 (es)
AU (1)	AU586187B2 (es)
CA (1)	CA1255685A (es)
DE (1)	DE3577849D1 (es)
DK (1)	DK407885A (es)
ES (1)	ES8605491A1 (es)
GR (1)	GR852189B (es)
PT (1)	PT81109B (es)
ZA (1)	ZA856943B (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1986001204A1 (en) *	1984-08-15	1986-02-27	Schering Aktiengesellschaft	New dopamine derivatives, process for their production, and their use as medicinal products
DE3728695A1 (de) *	1987-08-25	1989-03-09	Schering Ag	Neue benzimidazol-derivate
GB9210632D0 (en) *	1992-05-19	1992-07-01	Fisons Plc	Compounds
IE914003A1 (en) *	1990-11-20	1992-05-20	Astra Pharma Prod	Biologically Active Amines
TW356468B (en) *	1995-09-15	1999-04-21	Astra Pharma Prod	Benzothiazolone compounds useful as beta2-adrenoreceptor and dopamine DA2 receptor agonists process for preparing same and pharmaceutical compositions containing same
GB9526511D0 (en) *	1995-12-23	1996-02-28	Astra Pharma Prod	Pharmaceutically active compounds
TW200738658A (en)	2005-08-09	2007-10-16	Astrazeneca Ab	Novel compounds
TW200745067A (en)	2006-03-14	2007-12-16	Astrazeneca Ab	Novel compounds
TW200833670A (en)	2006-12-20	2008-08-16	Astrazeneca Ab	Novel compounds 569
GB0702458D0 (en)	2007-02-08	2007-03-21	Astrazeneca Ab	Salts 668
WO2009154557A1 (en)	2008-06-18	2009-12-23	Astrazeneca Ab	Benzoxazinone derivatives acting as beta2-adrenoreceptor agonist for the treatment of respiratory disorders

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4070478A (en) *	1977-02-17	1978-01-24	Merck & Co., Inc.	Benzimidazole substituted alanines
US4179505A (en) *	1977-03-30	1979-12-18	Janssen Pharmaceutica N.V.	5-[4-(Diarylmethyl)-1-piperazinylalkyl]benzimidazole derivatives
CA1108619A (en) *	1977-08-12	1981-09-08	Carl H. Ross	4-hydroxy-2-benzimidazolinone derivatives and the preparation thereof
US4314944A (en) *	1980-08-22	1982-02-09	Smithkline Corporation	4-Aminoalkyl-7-hydroxy-2(3H)-indolones

1984
- 1984-09-12 US US06/649,465 patent/US4554287A/en not_active Expired - Fee Related
1985
- 1985-09-05 CA CA000490062A patent/CA1255685A/en not_active Expired
- 1985-09-06 AU AU47144/85A patent/AU586187B2/en not_active Ceased
- 1985-09-06 EP EP85306335A patent/EP0175525B1/en not_active Expired - Lifetime
- 1985-09-06 AT AT85306335T patent/ATE53025T1/de not_active IP Right Cessation
- 1985-09-06 DE DE8585306335T patent/DE3577849D1/de not_active Expired - Fee Related
- 1985-09-06 DK DK407885A patent/DK407885A/da not_active Application Discontinuation
- 1985-09-10 JP JP60201480A patent/JPS6168473A/ja active Pending
- 1985-09-10 GR GR852189A patent/GR852189B/el unknown
- 1985-09-11 ZA ZA856943A patent/ZA856943B/xx unknown
- 1985-09-11 ES ES546884A patent/ES8605491A1/es not_active Expired
- 1985-09-11 PT PT81109A patent/PT81109B/pt unknown

Also Published As

Publication number	Publication date
AU586187B2 (en)	1989-07-06
EP0175525A1 (en)	1986-03-26
DK407885A (da)	1986-03-13
AU4714485A (en)	1986-03-20
ATE53025T1 (de)	1990-06-15
ES8605491A1 (es)	1986-03-16
EP0175525B1 (en)	1990-05-23
US4554287A (en)	1985-11-19
PT81109A (en)	1985-10-01
DK407885D0 (da)	1985-09-06
GR852189B (es)	1986-01-10
ZA856943B (en)	1986-06-25
JPS6168473A (ja)	1986-04-08
CA1255685A (en)	1989-06-13
PT81109B (en)	1987-07-06
DE3577849D1 (de)	1990-06-28

Publication	Publication Date	Title
ES8700663A1 (es)	1986-10-16	Un procedimiento para preparar un derivado de 1,3-benzotia- zol-2(3h)-ona o 1,3-benzoxazol-2(3h)-ona
KR860004882A (ko)	1986-07-14	항 알레르기제로서 유용한 신규의 산성 인돌화합물 및 그 제조방법
ES499870A0 (es)	1982-06-01	Un procedimiento para la preparacion de derivados de indano
ES539446A0 (es)	1986-06-01	Un procedimiento para preparar un derivado de dihidropiridazinona
ES8801245A1 (es)	1988-01-01	Un procedimiento para preparar derivados de piperidina
MA20459A1 (fr)	1985-12-31	Derives de l'imidazol-1,5-a/-pyridine substitues
DK407885D0 (da)	1985-09-06	7-(2-(dialkylamino)ethyl)-4-hydroxy-1,3-benzimidazol-2-oner
ES557061A0 (es)	1988-01-01	Un procedimiento para preparar un derivado de 1,5-benzotiazepina
ES524680A0 (es)	1984-12-16	Procedimiento de obtencion de nuevos compuestos derivados de la difenil-metilen-etilamina.
ES528561A0 (es)	1985-05-01	Un procedimiento para la preparacion de compuestos nitro alifaticos
ES547447A0 (es)	1986-07-16	Un procedimiento para la preparacion de nuevas 1,3-dimetil-1h-purin-2,6-dionas
ES547620A0 (es)	1987-02-16	Procedimiento para preparar pirazol (3,4-b) piridinamidas.
ES545775A0 (es)	1986-12-01	Un procedimiento para preparar un derivado de vinilisoquino-linas
ES8308833A1 (es)	1983-10-01	"un metodo para la preparacion de 3-fenil-1-indanaminas".
ES521440A0 (es)	1984-06-01	Un procedimiento para preparar derivados de imidazolina.
ES534858A0 (es)	1986-01-16	Procedimiento para la obtencion de derivados de 1-(4'-alquiltiofenil)-2-amino-1,3-propandiol
ES509154A0 (es)	1983-03-16	Un procedimiento para la preparacion de nuevos derivados del acido &-glutamil-diaminopimelilo.
ES531141A0 (es)	1985-09-01	Un procedimiento para preparar derivados de tropona