ES553675A0 - Un procedimiento para preparar nuevos esteres de acido androstano-17b-carboxilico - Google Patents

Un procedimiento para preparar nuevos esteres de acido androstano-17b-carboxilico

Info

Publication number: ES553675A0
Authority: ES; Spain
Prior art keywords: sub; hydrogen; straight; compounds; carbon atoms
Prior art date: 1985-04-04
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Granted

Application number

ES553675A

Other languages

English (en)

Other versions

ES8800264A1 (es

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Draco AB

Original Assignee

Draco AB

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1985-04-04

Filing date

1986-04-03

Publication date

1987-10-16

1986-04-03 Application filed by Draco AB filed Critical Draco AB

1987-10-16 Publication of ES8800264A1 publication Critical patent/ES8800264A1/es

1987-10-16 Publication of ES553675A0 publication Critical patent/ES553675A0/es

Status Expired legal-status Critical Current

Links

238000000034 method Methods 0.000 title abstract 3
229910052739 hydrogen Inorganic materials 0.000 abstract 8
239000001257 hydrogen Substances 0.000 abstract 8
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 4
125000001183 hydrocarbyl group Chemical group 0.000 abstract 4
150000002431 hydrogen Chemical class 0.000 abstract 4
125000004432 carbon atom Chemical group C* 0.000 abstract 3
150000001875 compounds Chemical class 0.000 abstract 3
ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 abstract 2
PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical compound FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 abstract 2
125000000217 alkyl group Chemical group 0.000 abstract 2
229910052801 chlorine Inorganic materials 0.000 abstract 2
239000000460 chlorine Substances 0.000 abstract 2
229910052731 fluorine Inorganic materials 0.000 abstract 2
239000011737 fluorine Substances 0.000 abstract 2
125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 2
229920006395 saturated elastomer Polymers 0.000 abstract 2
UPMXNNIRAGDFEH-UHFFFAOYSA-N 3,5-dibromo-4-hydroxybenzonitrile Chemical compound OC1=C(Br)C=C(C#N)C=C1Br UPMXNNIRAGDFEH-UHFFFAOYSA-N 0.000 abstract 1
OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 abstract 1
125000003545 alkoxy group Chemical group 0.000 abstract 1
125000004429 atom Chemical group 0.000 abstract 1
125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
229910052799 carbon Inorganic materials 0.000 abstract 1
125000004093 cyano group Chemical group *C#N 0.000 abstract 1
125000004122 cyclic group Chemical group 0.000 abstract 1
230000000694 effects Effects 0.000 abstract 1
229910052736 halogen Inorganic materials 0.000 abstract 1
125000005843 halogen group Chemical group 0.000 abstract 1
150000002367 halogens Chemical class 0.000 abstract 1
125000000623 heterocyclic group Chemical group 0.000 abstract 1
230000004968 inflammatory condition Effects 0.000 abstract 1
239000000543 intermediate Substances 0.000 abstract 1
-1 nitro, carboxy Chemical group 0.000 abstract 1
239000000825 pharmaceutical preparation Substances 0.000 abstract 1
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
229930195734 saturated hydrocarbon Natural products 0.000 abstract 1
125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
229930195735 unsaturated hydrocarbon Natural products 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
- C07J71/0005—Oxygen-containing hetero ring
- C07J71/0026—Oxygen-containing hetero ring cyclic ketals
- C07J71/0031—Oxygen-containing hetero ring cyclic ketals at positions 16, 17
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
General Chemical & Material Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Pain & Pain Management (AREA)
Bioinformatics & Cheminformatics (AREA)
Diabetes (AREA)
Endocrinology (AREA)
Rheumatology (AREA)
Engineering & Computer Science (AREA)
Steroid Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Pyrane Compounds (AREA)
Fats And Perfumes (AREA)
Threshing Machine Elements (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)
Pyrrole Compounds (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Crystals, And After-Treatments Of Crystals (AREA)

ES553675A 1985-04-04 1986-04-03 Un procedimiento para preparar nuevos esteres de acido androstano-17b-carboxilico Expired ES8800264A1 (es)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
SE8501693A SE8501693D0 (sv)	1985-04-04	1985-04-04	Novel 16,17-acetalsubstituted androstane-17beta-carboxylic acid esters

Publications (2)

Publication Number	Publication Date
ES8800264A1 ES8800264A1 (es)	1987-10-16
ES553675A0 true ES553675A0 (es)	1987-10-16

Family

ID=20359775

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
ES553675A Expired ES8800264A1 (es)	1985-04-04	1986-04-03	Un procedimiento para preparar nuevos esteres de acido androstano-17b-carboxilico
ES557314A Expired ES8802392A1 (es)	1985-04-04	1987-01-14	Un procedimiento para preparar nuevos esteres de acido androstano-17b-carboxilico

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
ES557314A Expired ES8802392A1 (es)	1985-04-04	1987-01-14	Un procedimiento para preparar nuevos esteres de acido androstano-17b-carboxilico

Country Status (31)

Country	Link
US (1)	US4950659A (es)
EP (2)	EP0197018B1 (es)
JP (1)	JPH0762028B2 (es)
KR (1)	KR930009444B1 (es)
CN (1)	CN1021444C (es)
AT (2)	ATE83241T1 (es)
AU (1)	AU590545B2 (es)
CA (1)	CA1333597C (es)
CS (1)	CS266581B2 (es)
DD (2)	DD247681A5 (es)
DE (2)	DE3689936T2 (es)
DK (3)	DK165638C (es)
ES (2)	ES8800264A1 (es)
FI (1)	FI85378C (es)
GR (1)	GR860902B (es)
HU (2)	HU196830B (es)
IE (1)	IE61474B1 (es)
IL (1)	IL78143A0 (es)
JO (1)	JO1479B1 (es)
LT (3)	LT3812B (es)
LV (3)	LV10960B (es)
MY (1)	MY102056A (es)
NO (1)	NO165298C (es)
NZ (1)	NZ215586A (es)
PH (2)	PH23547A (es)
PL (2)	PL150052B1 (es)
PT (1)	PT82340B (es)
RU (3)	RU1795972C (es)
SE (1)	SE8501693D0 (es)
UA (2)	UA19288A (es)
ZA (1)	ZA861884B (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
SE8501693D0 (sv)	1985-04-04	1985-04-04	Draco Ab	Novel 16,17-acetalsubstituted androstane-17beta-carboxylic acid esters
HU203769B (en) *	1989-03-09	1991-09-30	Richter Gedeon Vegyeszet	Process for producing new steroide derivatives and pharmaceutical compositions containing them
DE69311742T2 (de) *	1992-12-24	1998-01-08	Rhone Poulenc Rorer Ltd	Neue steroide
GB9423919D0 (en) *	1994-11-26	1995-01-11	Rhone Poulenc Rorer Ltd	Chemical process
GB0110411D0 (en) *	2001-04-27	2001-06-20	Astrazeneca Ab	Chemical process

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3828080A (en) *	1972-01-20	1974-08-06	Glaxo Lab Ltd	Androstane-17beta-carboxylic acids and processes for the preparation thereof
SE378109B (es) *	1972-05-19	1975-08-18	Bofors Ab
GB1438940A (en) *	1972-07-19	1976-06-09	Glaxo Lab Ltd	17beta-haloalkoxycarbonyl-17alpha-oxysteroids
GB1517278A (en) *	1974-08-30	1978-07-12	Glaxo Lab Ltd	Alkyl and haloalkyl androsta-1,4,15-triene and-4,15-diene-17beta-carboxylates
CH628355A5 (de) *	1976-02-24	1982-02-26	Ciba Geigy Ag	Verfahren zur herstellung neuer androstadien-17beta-carbonsaeuren und ihrer ester und salze.
US4198336A (en)	1978-04-05	1980-04-15	Syntex (U.S.A.) Inc.	Chemical process for preparing androsta-4-ene 17α-carboxylic acids
ZA814440B (en) *	1980-07-10	1982-10-27	Otsuka Pharma Co Ltd	Soft steroids having anti-inflammatory activity
SE449106B (sv) *	1980-07-10	1987-04-06	Otsuka Pharma Co Ltd	Steroid med anti-inflammatorisk verkan samt komposition innehallande denna
ZA817929B (en) *	1980-12-22	1982-10-27	Upjohn Co	5alpha-and 5beta-androstane-17beta-carboxylates
SE8306370D0 (sv) *	1983-11-18	1983-11-18	Draco Ab	Novel androstane-17beta-carboxylic acid esters, a process and intermediates for their preparation, compositions and method for the treatment of inflammatory conditions
SE8403905D0 (sv) *	1984-07-30	1984-07-30	Draco Ab	Liposomes and steroid esters
SE8501693D0 (sv)	1985-04-04	1985-04-04	Draco Ab	Novel 16,17-acetalsubstituted androstane-17beta-carboxylic acid esters
JP2687768B2 (ja) *	1991-07-30	1997-12-08	トヨタ自動車株式会社	エンジンの制御装置

1985
- 1985-04-04 SE SE8501693A patent/SE8501693D0/xx unknown
1986
- 1986-03-13 ZA ZA861884A patent/ZA861884B/xx unknown
- 1986-03-14 IL IL78143A patent/IL78143A0/xx not_active IP Right Cessation
- 1986-03-19 AU AU54868/86A patent/AU590545B2/en not_active Expired
- 1986-03-21 EP EP86850103A patent/EP0197018B1/en not_active Expired - Lifetime
- 1986-03-21 DE DE3689936T patent/DE3689936T2/de not_active Expired - Lifetime
- 1986-03-21 DE DE8686850103T patent/DE3687239T2/de not_active Expired - Lifetime
- 1986-03-21 EP EP89116726A patent/EP0355859B1/en not_active Expired - Lifetime
- 1986-03-21 AT AT86850103T patent/ATE83241T1/de not_active IP Right Cessation
- 1986-03-21 AT AT89116726T patent/ATE107657T1/de not_active IP Right Cessation
- 1986-03-25 US US06/843,771 patent/US4950659A/en not_active Expired - Lifetime
- 1986-03-25 FI FI861275A patent/FI85378C/fi not_active IP Right Cessation
- 1986-03-25 NZ NZ215586A patent/NZ215586A/en unknown
- 1986-03-25 DK DK138386A patent/DK165638C/da not_active IP Right Cessation
- 1986-04-01 JO JO19861479A patent/JO1479B1/en active
- 1986-04-02 CS CS862328A patent/CS266581B2/cs unknown
- 1986-04-03 UA UA4027897A patent/UA19288A/uk unknown
- 1986-04-03 ES ES553675A patent/ES8800264A1/es not_active Expired
- 1986-04-03 NO NO861313A patent/NO165298C/no unknown
- 1986-04-03 HU HU861423A patent/HU196830B/hu not_active IP Right Cessation
- 1986-04-03 IE IE87986A patent/IE61474B1/en not_active IP Right Cessation
- 1986-04-03 HU HU884925A patent/HU199872B/hu unknown
- 1986-04-03 JP JP61075677A patent/JPH0762028B2/ja not_active Expired - Lifetime
- 1986-04-03 UA UA4027252A patent/UA13319A/uk unknown
- 1986-04-03 RU SU864027252A patent/RU1795972C/ru active
- 1986-04-03 DD DD86288744A patent/DD247681A5/de unknown
- 1986-04-03 KR KR1019860002523A patent/KR930009444B1/ko not_active Expired - Lifetime
- 1986-04-03 CA CA000505744A patent/CA1333597C/en not_active Expired - Fee Related
- 1986-04-04 PL PL1986265699A patent/PL150052B1/pl unknown
- 1986-04-04 CN CN86102193A patent/CN1021444C/zh not_active Expired - Fee Related
- 1986-04-04 PL PL1986258775A patent/PL148272B1/pl unknown
- 1986-04-04 GR GR860902A patent/GR860902B/el unknown
- 1986-04-04 PT PT82340A patent/PT82340B/pt unknown
- 1986-07-31 RU SU864027897A patent/RU1779257C/ru active
1987
- 1987-01-14 ES ES557314A patent/ES8802392A1/es not_active Expired
- 1987-07-31 PH PH35610A patent/PH23547A/en unknown
- 1987-07-31 DD DD87305598A patent/DD261364A5/de unknown
- 1987-09-28 MY MYPI87001991A patent/MY102056A/en unknown
1988
- 1988-06-13 PH PH37057A patent/PH24369A/en unknown
1991
- 1991-11-05 RU SU915001895A patent/RU2081879C1/ru active
1992
- 1992-05-05 DK DK059392A patent/DK167150B1/da not_active IP Right Cessation
1993
- 1993-05-21 DK DK059693A patent/DK167574B1/da not_active IP Right Cessation
- 1993-06-30 LV LVP-93-818A patent/LV10960B/lv unknown
- 1993-06-30 LV LVP-93-861A patent/LV10281B/xx unknown
- 1993-07-30 LV LVP-93-1006A patent/LV10957B/lv unknown
- 1993-12-28 LT LTIP1677A patent/LT3812B/lt not_active IP Right Cessation
- 1993-12-28 LT LTIP1678A patent/LT3913B/lt not_active IP Right Cessation
- 1993-12-28 LT LTIP1676A patent/LT3811B/lt not_active IP Right Cessation

Also Published As

Publication number	Publication date
HU199872B (en)	1990-03-28
LV10957B (en)	1996-04-20
UA13319A (uk)	1997-02-28
JPH0762028B2 (ja)	1995-07-05
MY102056A (en)	1992-03-31
LV10960A (lv)	1995-12-20
IE61474B1 (en)	1994-11-02
LT3913B (en)	1996-04-25
IE860879L (en)	1986-10-04
ES8802392A1 (es)	1988-05-16
LV10281B (en)	1995-04-20
PL148272B1 (en)	1989-09-30
FI85378B (fi)	1991-12-31
DE3689936D1 (de)	1994-07-28
RU2081879C1 (ru)	1997-06-20
PT82340B (pt)	1988-10-14
EP0355859B1 (en)	1994-06-22
KR930009444B1 (ko)	1993-10-04
LV10281A (lv)	1994-10-20
EP0355859A1 (en)	1990-02-28
DK165638B (da)	1992-12-28
HU196830B (en)	1989-01-30
DK167574B1 (da)	1993-11-22
RU1795972C (ru)	1993-02-15
RU1779257C (ru)	1992-11-30
NO861313L (no)	1986-10-06
IL78143A0 (en)	1986-07-31
UA19288A (uk)	1997-12-25
DK138386A (da)	1986-10-05
LT3812B (en)	1996-03-25
DK59392D0 (da)	1992-05-05
DE3687239D1 (de)	1993-01-21
EP0197018A1 (en)	1986-10-08
DE3687239T2 (de)	1993-04-15
GR860902B (en)	1986-07-29
PH23547A (en)	1989-08-25
EP0197018B1 (en)	1992-12-09
ES557314A0 (es)	1988-05-16
US4950659A (en)	1990-08-21
PH24369A (en)	1990-06-13
CA1333597C (en)	1994-12-20
ES8800264A1 (es)	1987-10-16
DK167150B1 (da)	1993-09-06
CN86102193A (zh)	1987-09-02
PT82340A (en)	1986-05-01
LV10960B (en)	1996-08-20
DE3689936T2 (de)	1994-09-29
AU5486886A (en)	1986-10-16
CS266581B2 (en)	1990-01-12
FI85378C (fi)	1992-04-10
NO165298B (no)	1990-10-15
KR860008208A (ko)	1986-11-14
DD247681A5 (de)	1987-07-15
LV10957A (lv)	1995-12-20
NZ215586A (en)	1990-01-29
DK59693D0 (da)	1993-05-21
LTIP1677A (en)	1995-07-25
DK165638C (da)	1993-06-01
JO1479B1 (en)	1988-03-10
NO165298C (no)	1991-01-23
LTIP1678A (en)	1995-07-25
SE8501693D0 (sv)	1985-04-04
DK59693A (da)	1993-05-21
HUT40809A (en)	1987-02-27
PL150052B1 (en)	1990-04-30
CN1021444C (zh)	1993-06-30
LTIP1676A (en)	1995-07-25
CS232886A2 (en)	1989-04-14
DD261364A5 (de)	1988-10-26
ZA861884B (en)	1987-07-29
LT3811B (en)	1996-03-25
ATE107657T1 (de)	1994-07-15
FI861275A0 (fi)	1986-03-25
ATE83241T1 (de)	1992-12-15
JPS61236794A (ja)	1986-10-22
AU590545B2 (en)	1989-11-09
DK59392A (da)	1992-05-05
PL265699A1 (en)	1988-03-03
DK138386D0 (da)	1986-03-25
FI861275A7 (fi)	1986-10-05

Legal Events

Date	Code	Title	Description
2010-07-05	FD1A	Patent lapsed	Effective date: 20100623

Publication	Publication Date	Title
ES8103744A1 (es)	1981-03-16	Un metodo para la preparacion de derivados de ftalimidina
PT96897A (pt)	1991-10-31	Processo para a preparacao de novos compostos aril-e heteroariletilenicos e de composicoes farmaceuticas que os contem
DE3583872D1 (de)	1991-10-02	Dihydropyridin-derivate, verfahren zu ihrer herstellung, diese enthaltende pharmazeutische zusammensetzungen, und verfahren zur herstellung dieser zusammensetzungen.
SE8306370D0 (sv)	1983-11-18	Novel androstane-17beta-carboxylic acid esters, a process and intermediates for their preparation, compositions and method for the treatment of inflammatory conditions
ES553675A0 (es)	1987-10-16	Un procedimiento para preparar nuevos esteres de acido androstano-17b-carboxilico
MY102057A (en)	1992-03-31	Novel androstane-17b-carboxylic acid esters
ES470916A1 (es)	1979-10-01	un procedimiento para la preparacion de derivados de acidos4-hidroxi-2-quinolinon-3-carboxilicos
GB2004885A (en)	1979-04-11	Indolopyrones
JPS51136653A (en)	1976-11-26	Process for preparing novel organophosphorous compounds
JO1478B1 (en)	1988-03-10	Legacy of the new androstan-17 beta carboxylic acid