ES553738A0 - Un metodo de formacion de un reactivo de diagnostico especifico de sitio. - Google Patents

Un metodo de formacion de un reactivo de diagnostico especifico de sitio.

Info

Publication number
ES553738A0
ES553738A0 ES553738A ES553738A ES553738A0 ES 553738 A0 ES553738 A0 ES 553738A0 ES 553738 A ES553738 A ES 553738A ES 553738 A ES553738 A ES 553738A ES 553738 A0 ES553738 A0 ES 553738A0
Authority
ES
Spain
Prior art keywords
receptor
stimulated
site
platelet
antigen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES553738A
Other languages
English (en)
Other versions
ES8801439A1 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Scripps Research Institute
Original Assignee
Scripps Clinic and Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scripps Clinic and Research Foundation filed Critical Scripps Clinic and Research Foundation
Publication of ES553738A0 publication Critical patent/ES553738A0/es
Publication of ES8801439A1 publication Critical patent/ES8801439A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/10—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
    • A61K51/1027—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody against receptors, cell-surface antigens or cell-surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00—Preparations for testing in vivo
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/81—Packaged device or kit
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/948—Microorganisms using viruses or cell lines
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/806—Electrical property or magnetic property
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/808—Materials and products related to genetic engineering or hybrid or fused cell technology, e.g. hybridoma, monoclonal products
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/808—Materials and products related to genetic engineering or hybrid or fused cell technology, e.g. hybridoma, monoclonal products
    • Y10S530/809—Fused cells, e.g. hybridoma

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Optics & Photonics (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Epidemiology (AREA)
  • Physics & Mathematics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
ES553738A 1985-04-04 1986-04-04 Un metodo de formacion de un reactivo de diagnostico especifico de sitio. Expired ES8801439A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/720,032 US4820505A (en) 1985-04-04 1985-04-04 Detection of activated platelets with antibodies to thrombospondin

Publications (2)

Publication Number Publication Date
ES553738A0 true ES553738A0 (es) 1987-12-16
ES8801439A1 ES8801439A1 (es) 1987-12-16

Family

ID=24892375

Family Applications (1)

Application Number Title Priority Date Filing Date
ES553738A Expired ES8801439A1 (es) 1985-04-04 1986-04-04 Un metodo de formacion de un reactivo de diagnostico especifico de sitio.

Country Status (10)

Country Link
US (1) US4820505A (es)
EP (1) EP0216864B1 (es)
JP (1) JP2752614B2 (es)
AT (1) ATE76301T1 (es)
CA (1) CA1264029A (es)
DE (1) DE3685390D1 (es)
DK (1) DK173787B1 (es)
ES (1) ES8801439A1 (es)
NO (1) NO170128C (es)
WO (1) WO1986005693A1 (es)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5225181A (en) * 1985-06-07 1993-07-06 The Research Foundation Of State University Of New York Radiolabeled antiplatelet monoclonal antibody for imaging in-vivo thrombi
NO884566L (no) * 1987-10-15 1989-04-17 Univ Moskovsk Anvendelse av fluorderivater og kontrastpreparat for diagnostisering av ondartede neoplasmer.
US5372933A (en) * 1988-10-03 1994-12-13 The Scripps Research Institute Polypeptides that mimic receptor-induced binding sites, and methods of using same
US5024829A (en) * 1988-11-21 1991-06-18 Centocor, Inc. Method of imaging coronary thrombi
US5026537A (en) * 1989-04-06 1991-06-25 Centocor, Inc. Methods for imaging atherosclerotic plaque
US5185142A (en) * 1989-07-28 1993-02-09 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Antigen-specific composition and in vivo methods for detecting and localizing an antigenic site and for radiotherapy
US5116599A (en) * 1989-07-31 1992-05-26 Johns Hopkins Univ. Perfluoro-t-butyl-containing compounds for use in fluorine-19 nmr and/or mri
WO1991006858A1 (en) * 1989-11-03 1991-05-16 The United States Of America, As Represented By The Secretary, U.S. Department Of Commerce Novel monoclonal antibody against human platelets
DE59010815D1 (de) * 1989-12-27 1998-04-23 Boehringer Ingelheim Int Verwendung eines antikoagulant als diagnostikum
US5627036A (en) * 1989-12-27 1997-05-06 Boehringer Ingelheim International Gmbh Use of an anticoagulant as a diagnostic agent
US5192744A (en) * 1990-01-12 1993-03-09 Northwestern University Method of inhibiting angiogenesis of tumors
US5196309A (en) * 1990-11-15 1993-03-23 The Scripps Research Institute Characterization of platelet aggregation disorders
ES2083152T3 (es) * 1990-11-30 1996-04-01 Monoclonetics Int Metodos para el diagnostico de dolores cronicos lumbares y cervicales.
US5844097A (en) * 1990-11-30 1998-12-01 Monoclonetics International, Inc. Methods for the diagnosis of peripheral nerve damage
US5256538A (en) * 1991-03-08 1993-10-26 Board Of Regents, The University Of Texas System Detection of early platelet activation and prediagnosis of thrombotic events
US5807745A (en) * 1991-03-11 1998-09-15 New England Medical Center Hospitals, Inc. Method of inhibiting PADGEM-mediated or ELAM-1-mediated leukocyte adhesion using an inhibitor comprising a Lex core component
US5364612A (en) * 1991-05-06 1994-11-15 Immunomedics, Inc. Detection of cardiovascular lesions
SE469451B (sv) * 1991-06-28 1993-07-05 Anders Larsson Karakterisering eller bestaemning av maengden mammalieceller medelst antikroppar
WO1993007174A1 (en) * 1991-10-01 1993-04-15 The General Hospital Corporation Activation-dependent protein expressed on the surface of activated platelets and antibodies thereto
US5457028A (en) * 1992-04-22 1995-10-10 Milwaukee Heart Research Foundation Standard platelet samples and method for preparation thereof
EP0681485A1 (en) 1993-01-26 1995-11-15 Allergan, Inc. Compositions and methods to disinfect contact lenses
US5968477A (en) * 1994-01-24 1999-10-19 Neorx Corporation Radiolabeled annexin conjugates with hexose and a chelator
US20030220233A1 (en) * 1994-01-24 2003-11-27 Neorx Corporation Radiolabeled annexins
US7049140B1 (en) 1999-04-29 2006-05-23 Vanderbilt University X-ray guided drug delivery
US6159443A (en) * 1999-04-29 2000-12-12 Vanderbilt University X-ray guided drug delivery
US7306925B2 (en) 2001-11-09 2007-12-11 Vanderbilt University Phage antibodies to radiation-inducible neoantigens
US7906102B2 (en) 2001-10-03 2011-03-15 Vanderbilt University Ligands to radiation-induced molecules
US7029468B2 (en) * 2002-06-25 2006-04-18 Enpath Medical, Inc. Catheter assembly with side wall exit lumen and method therefor
US7655411B2 (en) * 2002-08-23 2010-02-02 W2 Holdings, Inc. Thrombospondin fragments and binding agents in the detection, diagnosis and evaluation of cancer
WO2016014939A1 (en) 2014-07-24 2016-01-28 Washington University Compositions targeting radiation-induced molecules and methods of use thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3789116A (en) * 1970-12-09 1974-01-29 Abbott Lab Fluorescent labeled antibody reagent
US4385046A (en) * 1980-12-15 1983-05-24 Minnesota Mining And Manufacturing Company Diagnostic radio-labeled polysaccharide derivatives
JPS6058927A (ja) * 1983-09-09 1985-04-05 Nippon Mejifuijitsukusu Kk 放射能標識血小板製剤
US4610960A (en) * 1983-12-21 1986-09-09 Wisconsin Alumni Research Foundation Monoclonal antibody to thrombospondin and method for assaying for and isolating thrombospondin
US4783330A (en) * 1984-11-15 1988-11-08 New England Medical Center Hospitals, Inc. Monoclonal antibodies to activated platelets

Also Published As

Publication number Publication date
ATE76301T1 (de) 1992-06-15
EP0216864B1 (en) 1992-05-20
US4820505A (en) 1989-04-11
EP0216864A1 (en) 1987-04-08
DK581386A (da) 1986-12-03
NO170128B (no) 1992-06-09
CA1264029A (en) 1989-12-27
NO864872D0 (no) 1986-12-04
DK581386D0 (da) 1986-12-03
DE3685390D1 (de) 1992-06-25
WO1986005693A1 (en) 1986-10-09
JPS62502964A (ja) 1987-11-26
ES8801439A1 (es) 1987-12-16
JP2752614B2 (ja) 1998-05-18
EP0216864A4 (en) 1989-09-26
DK173787B1 (da) 2001-10-22
NO170128C (no) 1992-09-16
NO864872L (no) 1986-12-04

Similar Documents

Publication Publication Date Title
NO170128C (no) Fremgangsmaate for dannelse av et monoklonalt antistoff for anvendelse som et diagnostisk posisjonsspesifikt reagens
ATE128183T1 (de) Peptide und antikörper, die die bindung von blutplättchen verhindern.
ATE66531T1 (de) Verfahren zum nachweis von immunkomplexen im serum.
ATE159982T1 (de) Antikörper mit modifiziertem kohlenhydratgehalt und verfahren zur herstellung und verwendung
ES556865A0 (es) Un metodo de inmunoensayo.
ES2082777T3 (es) Un metodo para la deteccion de un anti-cuerpo y antigeno en un inmunoensayo.
ATE123340T1 (de) Diagnostischer nachweis unter verwendung von chimären antikörpern.
DE3883073D1 (de) Einschritt-immuntest zur bestimmung von antigen-spezifischen antikoerpern aus einer der immunglobulin-klassen a, m, d oder e und dazu geeignetes mittel.
ATE48037T1 (de) Verfahren und reagenz zur verwendung zur bestimmung von pivka-ii.
DE3776525D1 (de) Immunochemisches verfahren zur bestimmung von stabilem glykosiliertem haemoglobin.
Stevens et al. Immunochemical and electrophoretic properties of oestrous rabbit uterine fluid proteins obtained by uterine ligation
DK199783A (da) Immunoglobulin-halvmolekyler og fremgangsmaade til fremstilling af hybrid-antistoffer
DE3587542D1 (de) Verfahren zur Diagnose in vitro von menschlichen Cytomegalovirusinfektionen und Anwendung von monoklonalen Antikörpern gegen Cytomegaloviren, die mit einer cytomegalovirusinduzierten Proteinkinase reagieren.
DE69026875D1 (de) Immunobestimmung von menschlichem osteocalcin, reagenz und satz dafür
DE58907087D1 (de) Verfahren zur Bestimmung von für ein Antigen klassenspezifischen Antikörpern und dazu geeignetes Reagenz.
ATE188551T1 (de) Feststellung von antikörperproduktion
DE3686717D1 (de) Immuntestverfahren.
DK414386A (da) Monoklonalt antistof, cellelinje til fremstilling deraf og antistoffets anvendelse
BARNHART Immunologic techniques
DE3785175D1 (de) A-assoziierte h-antigene, spezifische monoklonale antikoerper und methoden zu deren verwendung zur blutgruppenbestimmung.
ATE184286T1 (de) Hgpiib-fragmente und ihre verwendung in in-vitro- verfahren zur bestimmung von in vivo stattfindenden thrombotischen ereignissen
Maidment Jr et al. Isoelectric focusing analysis of soluble immune complexes bound to Protein A-Sepharose
Pitts et al. BRIEF REPORT: Defective Synthesis of IgM Antibodies in Macroglobulinemia
DE3853315D1 (de) Verfahren zur quantitativen Bestimmung von Serumproteinen in Körperflüssigkeiten und Mittel zur Durchführung des Verfahrens.
ATE43442T1 (de) Methode zur bestimmung des basischen fetoproteins und reagens hierfuer.

Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20071015