ES8101049A1 - Procedimiento mejorado para la preparacion de sulfonilureas - Google Patents

Procedimiento mejorado para la preparacion de sulfonilureas

Info

Publication number
ES8101049A1
ES8101049A1 ES490198A ES490198A ES8101049A1 ES 8101049 A1 ES8101049 A1 ES 8101049A1 ES 490198 A ES490198 A ES 490198A ES 490198 A ES490198 A ES 490198A ES 8101049 A1 ES8101049 A1 ES 8101049A1
Authority
ES
Spain
Prior art keywords
processes
preparation
pharmaceutical compositions
compositions containing
sulfonyl ureas
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES490198A
Other languages
English (en)
Other versions
ES490198A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst AG filed Critical Hoechst AG
Publication of ES8101049A1 publication Critical patent/ES8101049A1/es
Publication of ES490198A0 publication Critical patent/ES490198A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
    • C07D209/46—Iso-indoles; Hydrogenated iso-indoles with an oxygen atom in position 1
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
    • C07D217/24—Oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

PROCEDIMIENTO DE OBTENCION DE SULFONILUREAS. CONSISTE EN DESDOBLAR BENCENOSULFONIL-ISONREAESTERES, BENCESULFONIL-ISOTIONREAESTERES, BENCENO-SULFONIL-ACIDOS PARABANICOS O BENCENOSULFONIL-AMIDINAS DE ACIDOS HALOGENOFORMICOS SUSTITUIDOS CON EL GRUPO (I) O BENCENOSULFONILUREAS CON EL GRUPO (II). LOS PRODUCTOS OBTENIDOS PUEDEN SER TRATADOS CON AGENTES ALCALINOS, PARA FORMACION DE SALES. SE OBTIENEN COMPUESTOS DE FORMULA GENERAL (III). *FORMULA* DISMINUCION DEL NIVEL DE AZUCAR EN LA SANGRE. ''
ES490198A 1978-06-27 1980-04-01 Procedimiento mejorado para la preparacion de sulfonilureas Granted ES490198A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19782828079 DE2828079A1 (de) 1978-06-27 1978-06-27 Sulfonylharnstoffe und verfahren zu ihrer herstellung

Publications (2)

Publication Number Publication Date
ES8101049A1 true ES8101049A1 (es) 1980-12-01
ES490198A0 ES490198A0 (es) 1980-12-01

Family

ID=6042843

Family Applications (6)

Application Number Title Priority Date Filing Date
ES481755A Expired ES481755A1 (es) 1978-06-27 1979-06-21 Procedimiento mejorado para la preparacion de sulfonilureas.
ES490200A Expired ES8101050A1 (es) 1978-06-27 1980-04-01 Procedimiento mejorado para la preparacion de sulfonilureas
ES490201A Granted ES490201A0 (es) 1978-06-27 1980-04-01 Procedimiento mejorado para la preparacion de sulfonilureas
ES490198A Granted ES490198A0 (es) 1978-06-27 1980-04-01 Procedimiento mejorado para la preparacion de sulfonilureas
ES490199A Granted ES490199A0 (es) 1978-06-27 1980-04-01 Procedimiento mejorado para la preparacion de sulfonilureas
ES490202A Granted ES490202A0 (es) 1978-06-27 1980-04-01 Procedimiento mejorado para la preparacion de sulfonilureas

Family Applications Before (3)

Application Number Title Priority Date Filing Date
ES481755A Expired ES481755A1 (es) 1978-06-27 1979-06-21 Procedimiento mejorado para la preparacion de sulfonilureas.
ES490200A Expired ES8101050A1 (es) 1978-06-27 1980-04-01 Procedimiento mejorado para la preparacion de sulfonilureas
ES490201A Granted ES490201A0 (es) 1978-06-27 1980-04-01 Procedimiento mejorado para la preparacion de sulfonilureas

Family Applications After (2)

Application Number Title Priority Date Filing Date
ES490199A Granted ES490199A0 (es) 1978-06-27 1980-04-01 Procedimiento mejorado para la preparacion de sulfonilureas
ES490202A Granted ES490202A0 (es) 1978-06-27 1980-04-01 Procedimiento mejorado para la preparacion de sulfonilureas

Country Status (31)

Country Link
US (1) US4282239A (es)
EP (1) EP0006587B1 (es)
JP (1) JPS5511580A (es)
AR (1) AR223975A1 (es)
AT (1) ATE382T1 (es)
AU (1) AU527494B2 (es)
BE (1) BE877308A (es)
CA (1) CA1122598A (es)
CU (1) CU35107A (es)
DD (1) DD144539A5 (es)
DE (2) DE2828079A1 (es)
DK (1) DK269579A (es)
ES (6) ES481755A1 (es)
FI (1) FI792008A7 (es)
FR (1) FR2429786A1 (es)
GB (1) GB2024221A (es)
GR (1) GR74059B (es)
IL (1) IL57639A0 (es)
IT (1) IT1121923B (es)
JO (1) JO1010B1 (es)
LU (1) LU81423A1 (es)
MA (1) MA18501A1 (es)
MT (1) MTP848B (es)
MW (1) MW2079A1 (es)
NL (1) NL7904975A (es)
NO (1) NO792148L (es)
OA (1) OA06283A (es)
PT (1) PT69803A (es)
SE (1) SE7905557L (es)
ZA (1) ZA793178B (es)
ZM (1) ZM5879A1 (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2951135A1 (de) * 1979-12-19 1981-06-25 Hoechst Ag, 6230 Frankfurt Sulfonylharnstoffe, verfahren zu ihrer herstellung, pharmazeutische praeparate auf basis dieser verbindungen und ihre verwendung
DE3134780A1 (de) * 1981-09-02 1983-03-10 Hoechst Ag, 6000 Frankfurt "sulfonylharnstoffe, verfahren zu ihrer herstellung, pharmazeutische praeparate auf basis dieser verbindungen und ihre verwendung"
CN103058913B (zh) * 2012-12-13 2015-09-30 江苏弘和药物研发有限公司 5-氯异吲哚酮的合成方法

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1618389U (de) 1950-10-05 1950-12-28 Eisen Fuchs G M B H Endpreistabelle fuer walzeisen.
DE1670700U (de) 1952-11-12 1954-01-21 Siemens Ag Aufhaengevorrichtung fuer pendelleuchten.
DE1670660U (de) 1953-08-26 1954-01-21 Aerzener Bastkunst M Cramer Halter fuer blumentoepfe und pflanzenschalen.
LU47776A1 (es) * 1964-07-30 1966-07-13
DE1445774A1 (de) * 1964-07-30 1969-01-23 Hoechst Ag Verfahren zur Herstellung von Benzolsulfonylharnstoffen
FR1528139A (fr) * 1966-05-14 1968-06-07 Hoechst Ag Benzène-sulfonyl-urées et leur préparation
DE1670700B2 (de) * 1966-05-14 1978-06-22 Hoechst Ag, 6000 Frankfurt Benzolsulfonylharnstoffe, Verfahren zu ihrer Herstellung und deren Verwendung
LU56669A1 (es) * 1967-08-12 1970-02-18
DE2000339C3 (de) * 1970-01-05 1979-04-19 Dr. Karl Thomae Gmbh, 7950 Biberach Isochinolinderivate
US3819633A (en) * 1970-04-01 1974-06-25 Erba Carlo Spa (iso)quinolyl sulfonylureas having antidiabetic activity
GB1329812A (en) * 1971-02-15 1973-09-12 Science Union & Cie Benzenesulphonyl semicarbazides and a process for their preparation
BE791638A (fr) * 1971-11-20 1973-05-21 Hoechst Ag Sulfonyl-urees, leur procede de preparation et leurs applications
DE2238870C3 (de) 1972-08-07 1978-09-28 Hoechst Ag, 6000 Frankfurt Benzolsulfonylharnstoffe
IL45823A (en) * 1973-10-20 1977-10-31 Hoechst Ag Substituted 1-phenyl-4-alkyl(dialkyl or cyclic) aminoalkyl-1,4-dihydro-2h-isoquinoline-3-one derivatives
NL179275C (nl) * 1973-10-24 1986-08-18 Otsuka Pharma Co Ltd Werkwijze voor de bereiding van farmacologisch werkzame glycerol-derivaten en werkwijze voor de bereiding van preparaten die ze bevatten.
US4129729A (en) * 1978-01-03 1978-12-12 Monsanto Company 3-Phenacyl and phenacylidene phthalimidines and corresponding naphthoyl derivatives

Also Published As

Publication number Publication date
FR2429786B1 (es) 1982-06-18
ATE382T1 (de) 1981-11-15
MTP848B (en) 1980-06-24
ES490200A0 (es) 1980-12-01
LU81423A1 (de) 1980-01-22
CU35107A (en) 1982-08-24
GB2024221A (en) 1980-01-09
DK269579A (da) 1979-12-28
AU527494B2 (en) 1983-03-10
DE2961309D1 (en) 1982-01-14
FR2429786A1 (fr) 1980-01-25
AU4838079A (en) 1980-01-03
IL57639A0 (en) 1979-10-31
EP0006587A1 (de) 1980-01-09
NL7904975A (nl) 1980-01-02
DE2828079A1 (de) 1980-01-10
NO792148L (no) 1979-12-28
JPS5511580A (en) 1980-01-26
ZA793178B (en) 1980-06-25
MW2079A1 (en) 1980-11-12
EP0006587B1 (de) 1981-11-11
GR74059B (es) 1984-06-06
ES8101053A1 (es) 1980-12-01
ES490198A0 (es) 1980-12-01
DD144539A5 (de) 1980-10-22
ES8101051A1 (es) 1980-12-01
BE877308A (fr) 1979-12-27
ES8101050A1 (es) 1980-12-01
IT1121923B (it) 1986-04-23
OA06283A (fr) 1981-06-30
ES8100882A1 (es) 1980-12-01
ES490201A0 (es) 1980-12-01
AR223975A1 (es) 1981-10-15
ZM5879A1 (en) 1981-05-21
MA18501A1 (fr) 1979-12-31
FI792008A7 (fi) 1981-01-01
PT69803A (de) 1979-07-01
SE7905557L (sv) 1979-12-28
US4282239A (en) 1981-08-04
ES490202A0 (es) 1980-12-01
ES481755A1 (es) 1980-07-01
IT7923846A0 (it) 1979-06-25
JO1010B1 (en) 1982-07-10
ES490199A0 (es) 1980-12-01
CA1122598A (en) 1982-04-27

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20010301