ES8201151A1 - Procedimiento para la preparacion de acidos 5-sulfamoilorta-nilicos - Google Patents
Procedimiento para la preparacion de acidos 5-sulfamoilorta-nilicosInfo
- Publication number
- ES8201151A1 ES8201151A1 ES499509A ES499509A ES8201151A1 ES 8201151 A1 ES8201151 A1 ES 8201151A1 ES 499509 A ES499509 A ES 499509A ES 499509 A ES499509 A ES 499509A ES 8201151 A1 ES8201151 A1 ES 8201151A1
- Authority
- ES
- Spain
- Prior art keywords
- preparation
- formula
- sulfamoyl
- therapy
- compounds
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
- C07D333/20—Radicals substituted by singly bound hetero atoms other than halogen by nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D307/52—Radicals substituted by nitrogen atoms not forming part of a nitro radical
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Reproductive Health (AREA)
- Endocrinology (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
Abstract
PROCEDIMIENTO DE PREPARACION DE ACIDOS 5-SULFAMOILORTANILICOS DE FORMULA (I), EN QUE R ES ALCOHOLICO, ALQUENILO, CICLOALCOHILO O CICLOALCOHILALCOHILO, Y AR FENILO, TIENILO O FURILO. SE HACE REACCIONAR UN COMPUESTO DE FORMULA (III), EN QUE X ES HALOGENO, CON UNA AMINA DE FORMULA (III) EN UNA SOLUCION ORGANICA MUY POLAR, COMO DISOLVENTE, Y, OPCIONALMENTE, EN RPRESENCIA DE UN FIJADOR DE ACIDOS. LA REACCION S EFECTUA A TEMPERATURA DE 80-100 C, SIENDO X FLUOR, O DE 120-140 C, SIENDO X CLORO. LA AMINA EN EXCESO Y LOS DISOLVENTES SE SEPARAN POR DESTILACION. SE TRATA EL RESIDUO CON AGUA Y SE PURIFICA POR RECRISTALIZACION EN ALCOHOLES ACUOSOS. SE USAN EN FORMA DE SALES SODICAS O POTASICAS, EN PREPARADOS FARMACEUTICOS COMO AGENTES SALIDIURETICOS.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19803006686 DE3006686A1 (de) | 1980-02-22 | 1980-02-22 | 5-sulfamoyl-orthanilsaeuren, verfahren zu ihrer herstellung und ihre verwendung als heilmittel |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES8201151A1 true ES8201151A1 (es) | 1981-12-01 |
| ES499509A0 ES499509A0 (es) | 1981-12-01 |
Family
ID=6095322
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES499508A Granted ES499508A0 (es) | 1980-02-22 | 1981-02-17 | Procedimiento para la preparacion de acidos 5-sulfamoilorta-nilicos |
| ES499510A Expired ES8201152A1 (es) | 1980-02-22 | 1981-02-17 | Procedimiento para la preparacion de acidos 5-sulfamoilorta-nilicos |
| ES499509A Granted ES499509A0 (es) | 1980-02-22 | 1981-02-17 | Procedimiento para la preparacion de acidos 5-sulfamoilorta-nilicos |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES499508A Granted ES499508A0 (es) | 1980-02-22 | 1981-02-17 | Procedimiento para la preparacion de acidos 5-sulfamoilorta-nilicos |
| ES499510A Expired ES8201152A1 (es) | 1980-02-22 | 1981-02-17 | Procedimiento para la preparacion de acidos 5-sulfamoilorta-nilicos |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US4339446A (es) |
| EP (1) | EP0034746B1 (es) |
| JP (1) | JPS56142257A (es) |
| AR (1) | AR230622A1 (es) |
| AT (1) | ATE5883T1 (es) |
| AU (1) | AU536892B2 (es) |
| CA (1) | CA1155449A (es) |
| DE (2) | DE3006686A1 (es) |
| DK (1) | DK77881A (es) |
| ES (3) | ES499508A0 (es) |
| FI (1) | FI810510A7 (es) |
| HU (1) | HU187300B (es) |
| IL (1) | IL62176A0 (es) |
| ZA (1) | ZA811144B (es) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1921845A (zh) * | 2004-02-20 | 2007-02-28 | 安万特药物公司 | 作为hm74调节剂的呋塞米衍生物以及它们用于治疗炎症的用途 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3875150A (en) * | 1969-04-29 | 1975-04-01 | Leo Pharm Prod Ltd | New sulfamyl-anthranilic acids |
| US3812104A (en) * | 1971-06-25 | 1974-05-21 | Ciba Geigy Corp | 5-arylsulfamyl-anthranilic acids |
| GB1364366A (en) * | 1971-07-20 | 1974-08-21 | Tera Middle East Pharmaceutica | Derivatives of 4-chloro-5-sulphamoyl-anthranilic acid their preparation and pahamaceutical compositions comprising them |
| DE2142758A1 (de) * | 1971-08-26 | 1973-03-01 | Ciba Geigy Ag | Aromatische sulfamoylverbindungen |
| DE2232457A1 (de) * | 1972-07-01 | 1974-01-10 | Boehringer Mannheim Gmbh | Neue 3-alkyl-4-sulfamoylanilinderivate |
-
1980
- 1980-02-22 DE DE19803006686 patent/DE3006686A1/de not_active Withdrawn
-
1981
- 1981-02-10 AT AT81100911T patent/ATE5883T1/de not_active IP Right Cessation
- 1981-02-10 EP EP81100911A patent/EP0034746B1/de not_active Expired
- 1981-02-10 DE DE8181100911T patent/DE3161905D1/de not_active Expired
- 1981-02-17 ES ES499508A patent/ES499508A0/es active Granted
- 1981-02-17 ES ES499510A patent/ES8201152A1/es not_active Expired
- 1981-02-17 ES ES499509A patent/ES499509A0/es active Granted
- 1981-02-19 FI FI810510A patent/FI810510A7/fi not_active Application Discontinuation
- 1981-02-20 AU AU67507/81A patent/AU536892B2/en not_active Ceased
- 1981-02-20 CA CA000371434A patent/CA1155449A/en not_active Expired
- 1981-02-20 AR AR284374A patent/AR230622A1/es active
- 1981-02-20 ZA ZA00811144A patent/ZA811144B/xx unknown
- 1981-02-20 HU HU81415A patent/HU187300B/hu unknown
- 1981-02-20 DK DK77881A patent/DK77881A/da not_active Application Discontinuation
- 1981-02-20 US US06/236,605 patent/US4339446A/en not_active Expired - Fee Related
- 1981-02-20 JP JP2417181A patent/JPS56142257A/ja active Pending
- 1981-02-20 IL IL62176A patent/IL62176A0/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ZA811144B (en) | 1982-03-31 |
| IL62176A0 (en) | 1981-03-31 |
| ES8201150A1 (es) | 1981-12-01 |
| FI810510L (fi) | 1981-08-23 |
| ES499510A0 (es) | 1981-12-01 |
| AR230622A1 (es) | 1984-05-31 |
| DE3006686A1 (de) | 1981-08-27 |
| ATE5883T1 (de) | 1984-02-15 |
| US4339446A (en) | 1982-07-13 |
| AU536892B2 (en) | 1984-05-31 |
| AU6750781A (en) | 1982-09-16 |
| JPS56142257A (en) | 1981-11-06 |
| CA1155449A (en) | 1983-10-18 |
| ES499508A0 (es) | 1981-12-01 |
| HU187300B (en) | 1985-12-28 |
| DK77881A (da) | 1981-08-23 |
| DE3161905D1 (en) | 1984-02-23 |
| EP0034746A1 (de) | 1981-09-02 |
| EP0034746B1 (de) | 1984-01-18 |
| ES499509A0 (es) | 1981-12-01 |
| ES8201152A1 (es) | 1981-12-01 |
| FI810510A7 (fi) | 1981-08-23 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ES8604226A1 (es) | Procedimiento para preparar (2-oxo-1, 2, 3, 5-tetrahidroimidazo (2, 1-b) quinazolinil) oxialquilamidas | |
| ES8507549A1 (es) | Procedimiento para preparar 9-1 3 dihidroxi 2 propoximetil guanina y sales farmaceuticamente aceptable | |
| DK148279C (da) | Analogifremgangsmaade til fremstilling af 9-substituerede guaninderivater eller fysiologisk acceptable salte eller optiske isomerer deraf | |
| CU22305A3 (es) | Procedimiento para la preparacion de un derivado de aminoacidos | |
| ES8504131A1 (es) | Un procedimiento para la preparacion de 4-amino-6,7-dimetoxi quinoles. | |
| ES2013067A6 (es) | Un procedimiento para producir un derivado de piperazina. | |
| ES8503669A1 (es) | Procedimiento para preparar derivados n-imidazolilicos de compuestos biciclicos. | |
| ES8401492A1 (es) | Procedimiento para la preparacion de derivados de cefem. | |
| ES8405778A1 (es) | Procedimiento para la preparacion de nuevos benzo-heterociclos. | |
| ES8703405A1 (es) | Un procedimiento para la preparacion de derivados de acetanilida | |
| DK148183D0 (da) | Fremgangsmade til fremstilling af imidazolylphenyl-tetrahydropyridaziner | |
| ES8303404A1 (es) | Procedimiento para preparar 3-amino-sidnoniminas sustituidas. | |
| ES8301884A1 (es) | Procedimiento para la preparacion de derivados de ciclohexe-no | |
| ES8604180A1 (es) | Procedimiento para la obtencion de azoles 2, 4, 5-trisustituidos | |
| DK204686D0 (da) | Quinolylglycinamidderivater og fremgangsmaade til fremstilling deraf | |
| ES8603810A1 (es) | Procedimiento de preparacion de nuevos derivados a-etilben- zol con un grupo dietilaminoalcoxi sustituido y sus sales deadicion acidas y amonicas cuaternarias | |
| ES8105692A1 (es) | Un procedimiento para preparar acidos 2-nitrobenzoicos sus- tituidos con fenoxi en la posicion 5 | |
| ES8304975A1 (es) | "procedimiento para la preparacion de derivados triptaminicos sustituidos de tieniloxipropanolaminas, racemicos y opticamente activos". | |
| ES8503676A1 (es) | Procedimiento de producir derivados de acido oxazolacetico | |
| DK267183A (da) | Theno-pyridinonderivat og fremgangsmaade til fremstilling deraf | |
| ES8703423A1 (es) | Un procedimiento para producir un derivado de acido indola- cetico | |
| ES8207505A1 (es) | Procedimiento para la preparacion de derivados de fenoxi- aminopropanol substituidos | |
| ES8603828A1 (es) | Procedimiento de preparacion de nuevos derivados a-etilben- zol con un grupo piperidinopropanolico sustituido y de sus sales de adicion acidas y amonicas cuaternarias | |
| DK401683A (da) | Substituerede benzensulfonsyreestere, fremgangsmaade til deres fremstilling og deres anvendelse som laegemidler | |
| ES8504135A1 (es) | Procedimiento para la obtencion de derivados de diaril-imidazol.(como desglose y con prioridad de la patente espanola n 504.787, presentada el 17 de agosto de 1981) |