ES8201151A1 - Procedimiento para la preparacion de acidos 5-sulfamoilorta-nilicos - Google Patents
Procedimiento para la preparacion de acidos 5-sulfamoilorta-nilicosInfo
- Publication number
- ES8201151A1 ES8201151A1 ES499509A ES499509A ES8201151A1 ES 8201151 A1 ES8201151 A1 ES 8201151A1 ES 499509 A ES499509 A ES 499509A ES 499509 A ES499509 A ES 499509A ES 8201151 A1 ES8201151 A1 ES 8201151A1
- Authority
- ES
- Spain
- Prior art keywords
- preparation
- formula
- sulfamoyl
- therapy
- compounds
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
- C07D333/20—Radicals substituted by singly bound hetero atoms other than halogen by nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D307/52—Radicals substituted by nitrogen atoms not forming part of a nitro radical
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Urology & Nephrology (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
PROCEDIMIENTO DE PREPARACION DE ACIDOS 5-SULFAMOILORTANILICOS DE FORMULA (I), EN QUE R ES ALCOHOLICO, ALQUENILO, CICLOALCOHILO O CICLOALCOHILALCOHILO, Y AR FENILO, TIENILO O FURILO. SE HACE REACCIONAR UN COMPUESTO DE FORMULA (III), EN QUE X ES HALOGENO, CON UNA AMINA DE FORMULA (III) EN UNA SOLUCION ORGANICA MUY POLAR, COMO DISOLVENTE, Y, OPCIONALMENTE, EN RPRESENCIA DE UN FIJADOR DE ACIDOS. LA REACCION S EFECTUA A TEMPERATURA DE 80-100 C, SIENDO X FLUOR, O DE 120-140 C, SIENDO X CLORO. LA AMINA EN EXCESO Y LOS DISOLVENTES SE SEPARAN POR DESTILACION. SE TRATA EL RESIDUO CON AGUA Y SE PURIFICA POR RECRISTALIZACION EN ALCOHOLES ACUOSOS. SE USAN EN FORMA DE SALES SODICAS O POTASICAS, EN PREPARADOS FARMACEUTICOS COMO AGENTES SALIDIURETICOS.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19803006686 DE3006686A1 (de) | 1980-02-22 | 1980-02-22 | 5-sulfamoyl-orthanilsaeuren, verfahren zu ihrer herstellung und ihre verwendung als heilmittel |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES8201151A1 true ES8201151A1 (es) | 1981-12-01 |
| ES499509A0 ES499509A0 (es) | 1981-12-01 |
Family
ID=6095322
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES499508A Granted ES499508A0 (es) | 1980-02-22 | 1981-02-17 | Procedimiento para la preparacion de acidos 5-sulfamoilorta-nilicos |
| ES499510A Granted ES499510A0 (es) | 1980-02-22 | 1981-02-17 | Procedimiento para la preparacion de acidos 5-sulfamoilorta-nilicos |
| ES499509A Granted ES499509A0 (es) | 1980-02-22 | 1981-02-17 | Procedimiento para la preparacion de acidos 5-sulfamoilorta-nilicos |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES499508A Granted ES499508A0 (es) | 1980-02-22 | 1981-02-17 | Procedimiento para la preparacion de acidos 5-sulfamoilorta-nilicos |
| ES499510A Granted ES499510A0 (es) | 1980-02-22 | 1981-02-17 | Procedimiento para la preparacion de acidos 5-sulfamoilorta-nilicos |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US4339446A (es) |
| EP (1) | EP0034746B1 (es) |
| JP (1) | JPS56142257A (es) |
| AR (1) | AR230622A1 (es) |
| AT (1) | ATE5883T1 (es) |
| AU (1) | AU536892B2 (es) |
| CA (1) | CA1155449A (es) |
| DE (2) | DE3006686A1 (es) |
| DK (1) | DK77881A (es) |
| ES (3) | ES499508A0 (es) |
| FI (1) | FI810510L (es) |
| HU (1) | HU187300B (es) |
| IL (1) | IL62176A0 (es) |
| ZA (1) | ZA811144B (es) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2005216879B2 (en) * | 2004-02-20 | 2009-12-10 | Aventis Pharmaceuticals Inc | Furosemide derivatives as modulators of HM74 and their use for the treatment of inflammation |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3875150A (en) * | 1969-04-29 | 1975-04-01 | Leo Pharm Prod Ltd | New sulfamyl-anthranilic acids |
| US3812104A (en) * | 1971-06-25 | 1974-05-21 | Ciba Geigy Corp | 5-arylsulfamyl-anthranilic acids |
| GB1364366A (en) * | 1971-07-20 | 1974-08-21 | Tera Middle East Pharmaceutica | Derivatives of 4-chloro-5-sulphamoyl-anthranilic acid their preparation and pahamaceutical compositions comprising them |
| DE2142758A1 (de) * | 1971-08-26 | 1973-03-01 | Ciba Geigy Ag | Aromatische sulfamoylverbindungen |
| DE2232457A1 (de) * | 1972-07-01 | 1974-01-10 | Boehringer Mannheim Gmbh | Neue 3-alkyl-4-sulfamoylanilinderivate |
-
1980
- 1980-02-22 DE DE19803006686 patent/DE3006686A1/de not_active Withdrawn
-
1981
- 1981-02-10 EP EP81100911A patent/EP0034746B1/de not_active Expired
- 1981-02-10 AT AT81100911T patent/ATE5883T1/de not_active IP Right Cessation
- 1981-02-10 DE DE8181100911T patent/DE3161905D1/de not_active Expired
- 1981-02-17 ES ES499508A patent/ES499508A0/es active Granted
- 1981-02-17 ES ES499510A patent/ES499510A0/es active Granted
- 1981-02-17 ES ES499509A patent/ES499509A0/es active Granted
- 1981-02-19 FI FI810510A patent/FI810510L/fi not_active Application Discontinuation
- 1981-02-20 ZA ZA00811144A patent/ZA811144B/xx unknown
- 1981-02-20 AR AR284374A patent/AR230622A1/es active
- 1981-02-20 DK DK77881A patent/DK77881A/da not_active Application Discontinuation
- 1981-02-20 CA CA000371434A patent/CA1155449A/en not_active Expired
- 1981-02-20 HU HU81415A patent/HU187300B/hu unknown
- 1981-02-20 AU AU67507/81A patent/AU536892B2/en not_active Ceased
- 1981-02-20 JP JP2417181A patent/JPS56142257A/ja active Pending
- 1981-02-20 US US06/236,605 patent/US4339446A/en not_active Expired - Fee Related
- 1981-02-20 IL IL62176A patent/IL62176A0/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP0034746B1 (de) | 1984-01-18 |
| AU536892B2 (en) | 1984-05-31 |
| ES8201150A1 (es) | 1981-12-01 |
| DE3161905D1 (en) | 1984-02-23 |
| ES8201152A1 (es) | 1981-12-01 |
| DK77881A (da) | 1981-08-23 |
| FI810510A7 (fi) | 1981-08-23 |
| IL62176A0 (en) | 1981-03-31 |
| AU6750781A (en) | 1982-09-16 |
| ES499508A0 (es) | 1981-12-01 |
| ATE5883T1 (de) | 1984-02-15 |
| DE3006686A1 (de) | 1981-08-27 |
| CA1155449A (en) | 1983-10-18 |
| ES499509A0 (es) | 1981-12-01 |
| ES499510A0 (es) | 1981-12-01 |
| ZA811144B (en) | 1982-03-31 |
| AR230622A1 (es) | 1984-05-31 |
| JPS56142257A (en) | 1981-11-06 |
| FI810510L (fi) | 1981-08-23 |
| EP0034746A1 (de) | 1981-09-02 |
| US4339446A (en) | 1982-07-13 |
| HU187300B (en) | 1985-12-28 |
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