ES8201315A1 - Procedimiento para la deteccion y la determinacion de un an-tigeno o anticuerpo - Google Patents

Procedimiento para la deteccion y la determinacion de un an-tigeno o anticuerpo

Info

Publication number
ES8201315A1
ES8201315A1 ES498270A ES498270A ES8201315A1 ES 8201315 A1 ES8201315 A1 ES 8201315A1 ES 498270 A ES498270 A ES 498270A ES 498270 A ES498270 A ES 498270A ES 8201315 A1 ES8201315 A1 ES 8201315A1
Authority
ES
Spain
Prior art keywords
reagent
antibody
antigen
latex
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES498270A
Other languages
English (en)
Other versions
ES498270A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Siemens Healthcare Diagnostics GmbH Germany
Original Assignee
Behringwerke AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Behringwerke AG filed Critical Behringwerke AG
Publication of ES8201315A1 publication Critical patent/ES8201315A1/es
Publication of ES498270A0 publication Critical patent/ES498270A0/es
Granted legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/805—Optical property

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Materials For Medical Uses (AREA)
  • Non-Silver Salt Photosensitive Materials And Non-Silver Salt Photography (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

PROCEDIMIENTO PARA LA DETECCION Y LA DETERMINACION DE UN ANTIGENO O ANTICUERPO. CONSISTENTE EN HACER REACCIONAR CON EL ANTIGENO O ANTICUERPO A DETERMINAR CON UN REACTIVO DE LATEX. ESTE REACTIVO ESTA CONSTITUIDO POR UNA SUSPENSION DE PARTICULAS DE LATEX DE DOS MARGENES DIFERENTES DE TAMAÑOS, PREFERENTEMENTE ENTRE 0,15 HASTA 0,25 UM Y 0,5 HASTA 0,8 UM, RESPECTIVAMENTE. ESTAS PARTICULASS ESTAN CARGADAS, POR LO MENOS, CON DOS CANTIDADES DIFERENTES DEL MISMO ANTIGENO O ANTICUERPO. EL REACTIVO SE REUNE EN FASE LIQUIDA CON EL ANTIGENO O ANTICUERPO A DETERMINAR, PARA QUE TENGA LUGAR LA REACCION CORRESPONDIENTE, EFECTUANDOSE LA DETERMINACION POR MEDIDA DE LA DISPERSION DE LA LUZ.
ES498270A 1979-05-07 1980-12-31 Procedimiento para la deteccion y la determinacion de un an-tigeno o anticuerpo Granted ES498270A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19792918342 DE2918342A1 (de) 1979-05-07 1979-05-07 Latex-reagenz

Publications (2)

Publication Number Publication Date
ES8201315A1 true ES8201315A1 (es) 1981-12-01
ES498270A0 ES498270A0 (es) 1981-12-01

Family

ID=6070116

Family Applications (2)

Application Number Title Priority Date Filing Date
ES491029A Expired ES8200770A1 (es) 1979-05-07 1980-04-30 Procedimiento de preparacion de un reactivo de latex para la deteccion y la determinacion de anticuerpos o antigenos.
ES498270A Granted ES498270A0 (es) 1979-05-07 1980-12-31 Procedimiento para la deteccion y la determinacion de un an-tigeno o anticuerpo

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES491029A Expired ES8200770A1 (es) 1979-05-07 1980-04-30 Procedimiento de preparacion de un reactivo de latex para la deteccion y la determinacion de anticuerpos o antigenos.

Country Status (8)

Country Link
US (1) US4305925A (es)
EP (1) EP0019741B1 (es)
JP (1) JPS55151264A (es)
AT (1) ATE16130T1 (es)
AU (1) AU527485B2 (es)
DE (2) DE2918342A1 (es)
DK (1) DK153589C (es)
ES (2) ES8200770A1 (es)

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EP0070527B1 (en) * 1981-07-17 1985-06-19 Toray Industries, Inc. Method of assaying biologically active substances and labelling agents therefor
DE3145082A1 (de) * 1981-11-13 1983-05-19 Behringwerke Ag, 3550 Marburg "ein latex, biologisch aktive latexkonjugate und verfahren zu ihrer herstellung"
US4543339A (en) * 1982-03-16 1985-09-24 Oneill Christopher Early pregnancy detection by detecting enhanced blood platelet activation
US4766083A (en) * 1982-04-04 1988-08-23 Wako Pure Chemical Industries, Ltd. Method for the photometric determination of biological agglutination
JPS58209994A (ja) * 1982-05-10 1983-12-07 Fujirebio Inc 活性蛋白等固定化物を用いた抗原の測定方法
US4459361A (en) * 1982-06-04 1984-07-10 Angenics, Inc. Ligand assay with one or two particulate reagents and filter
GB2123146B (en) * 1982-06-28 1985-09-25 Abbott Lab Dual parameter flow immunoassays
EP0101228B1 (en) * 1982-08-06 1986-10-08 International Institute Of Cellular And Molecular Pathology (Icp) Particle agglutination assay of antigens
FR2531718B1 (fr) * 1982-08-16 1986-11-21 Sanofi Sa Reactif permettant un dosage de tres haute sensibilite de l'antigene caracteristique du virus de l'hepatite b dans les liquides biologiques humains
US4595661A (en) * 1983-11-18 1986-06-17 Beckman Instruments, Inc. Immunoassays and kits for use therein which include low affinity antibodies for reducing the hook effect
US4590169A (en) * 1983-11-18 1986-05-20 Beckman Instruments, Inc. Direct particle agglutination immunoassays avoiding false negatives at high antigen concentrations
WO1985004426A1 (en) * 1984-03-26 1985-10-10 International Health Services A method of determining the clotting time of blood and particulate reagents therefor
US4665020A (en) * 1984-05-30 1987-05-12 United States Department Of Energy Flow cytometer measurement of binding assays
JPH0650314B2 (ja) * 1984-09-08 1994-06-29 オリンパス光学工業株式会社 免疫反応測定装置
US4762413A (en) * 1984-09-07 1988-08-09 Olympus Optical Co., Ltd. Method and apparatus for measuring immunological reaction with the aid of fluctuation in intensity of scattered light
DE3662730D1 (en) * 1985-01-24 1989-05-11 Inst Int Pathologie Cellulaire Immunoassay method for antibodies of different classes in a liquid sample
DE3507574A1 (de) * 1985-03-04 1986-09-04 Gödecke AG, 1000 Berlin Zweistufiger agglutinationsschnelltest zum kombinierten nachweis "seropositiver" und "seronegativer" rheumafaktoren
GB8526355D0 (en) * 1985-10-25 1985-11-27 Alta Diagnostic Machines Ltd Determination of antibody content of blood
US5770459A (en) * 1986-04-30 1998-06-23 Igen International, Inc. Methods and apparatus for improved luminescence assays using particle concentration, electrochemical generation of chemiluminescence detection
GB8621495D0 (en) * 1986-09-05 1986-10-15 Acade Diagnostic Systems Sa Nv Assay
JP2588174B2 (ja) * 1986-09-08 1997-03-05 三菱化学株式会社 抗原−抗体反応の測定法
US6881589B1 (en) 1987-04-30 2005-04-19 Bioveris Corporation Electrochemiluminescent localizable complexes for assay compositions
US5935779A (en) * 1988-11-03 1999-08-10 Igen International Inc. Methods for improved particle electrochemiluminescence assay
US5746974A (en) * 1988-11-03 1998-05-05 Igen International, Inc. Apparatus for improved luminescence assays using particle concentration, electrochemical generation of chemiluminescence and chemiluminescence detection
US5962218A (en) * 1988-11-03 1999-10-05 Igen International Inc. Methods and apparatus for improved luminescence assays
US5779976A (en) * 1988-11-03 1998-07-14 Igen International, Inc. Apparatus for improved luminescence assays
US5705402A (en) * 1988-11-03 1998-01-06 Igen International, Inc. Method and apparatus for magnetic microparticulate based luminescence assay including plurality of magnets
CA2023804C (en) * 1989-08-23 1999-05-25 Takeshi Miyazaki Method for measuring an immunologically active material and apparatus suitable for practicing said method
DE69017471D1 (de) * 1990-02-22 1995-04-06 Univ Mcgill Feststoff-phase-interferometrisches immunotestsystem.
US5269937A (en) * 1990-10-23 1993-12-14 Cetus Corporation HPLC light scattering detector for biopolymers
US5250186A (en) * 1990-10-23 1993-10-05 Cetus Corporation HPLC light scattering detector for biopolymers
ZA92803B (en) 1991-02-06 1992-11-25 Igen Inc Method and apparatus for magnetic microparticulate based luminescene asay including plurality of magnets
US5290707A (en) * 1991-11-25 1994-03-01 The United States Of America As Represented By The Secretary Of The Army Method for detection of microorganisms
DE4202924A1 (de) * 1992-02-01 1993-08-05 Behringwerke Ag Verfahren zur bestimmung von rheumafaktoren und mittel zur durchfuehrung des verfahrens
TW239881B (es) * 1992-12-22 1995-02-01 Sienna Biotech Inc
US6200820B1 (en) 1992-12-22 2001-03-13 Sienna Biotech, Inc. Light scatter-based immunoassay
US6290991B1 (en) 1994-12-02 2001-09-18 Quandrant Holdings Cambridge Limited Solid dose delivery vehicle and methods of making same
US6019968A (en) * 1995-04-14 2000-02-01 Inhale Therapeutic Systems, Inc. Dispersible antibody compositions and methods for their preparation and use
US5628432A (en) * 1996-04-03 1997-05-13 Mosley; Julius Personal cooling system
JP3652029B2 (ja) * 1996-10-16 2005-05-25 積水化学工業株式会社 高感度免疫測定法
US5858648A (en) * 1996-11-04 1999-01-12 Sienna Biotech, Inc. Assays using reference microparticles
JP4896347B2 (ja) * 2000-06-30 2012-03-14 協和メデックス株式会社 不溶性担体粒子比濁免疫測定用試薬
JPWO2002079782A1 (ja) * 2001-03-30 2004-07-22 株式会社三菱化学ヤトロン エラスターゼ１の免疫分析用試薬及び免疫分析方法並びに膵疾患の検出方法
ATE465409T1 (de) * 2001-07-02 2010-05-15 Sekisui Medical Co Ltd Latex-trägerpartikel für ein testreagenz, und testreagenz
WO2005114218A2 (en) * 2004-05-15 2005-12-01 Genentech, Inc. Cross-screening system and methods for detecting a molecule having binding affinity for a target molecule
JP4331073B2 (ja) * 2004-08-31 2009-09-16 デンカ生研株式会社 抗原の測定方法及びそのための試薬
ES2675044T3 (es) 2005-06-03 2018-07-06 Board Of Regents Of The University Of Texas System Electroquímica y quimioluminiscencia electrogenerada con un único electrodo faradaico
WO2009066731A1 (ja) * 2007-11-21 2009-05-28 Arkray, Inc. 測定試薬、それを用いた免疫比濁法および検体分析用具
CN105181962B (zh) * 2015-09-02 2016-09-14 郁东 一种类风湿因子检测试剂
JP6978489B2 (ja) 2017-03-28 2021-12-08 デンカ株式会社 膜担体、並びにそれを用いた液体試料検査キット及びその製造方法
DE102021111494A1 (de) 2021-05-04 2022-11-10 Atral-Secal Gmbh Nachweisgerät sowie ein Nachweisverfahren für in Luft enthaltene pathogene Substanzen
DE102021126818A1 (de) 2021-10-15 2023-04-20 Atral-Secal Gmbh Nachweisgerät sowie ein Nachweisverfahren für in Luft enthaltene pathogene Substanzen
CN114935655B (zh) * 2022-06-16 2024-02-20 安徽农业大学 一种猪il-17胶乳增强免疫比浊法检测试剂盒及其制备使用方法
CN115754312A (zh) * 2022-10-12 2023-03-07 湖南菲科生物技术有限公司 氧化型低密度脂蛋白检测试剂盒及其制备方法
DE102022132609A1 (de) 2022-12-08 2024-06-13 Hager Safety Deutschland Gmbh Nachweisgerät sowie ein Nachweisverfahren für in Luft enthaltene pathogene Substanzen

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GB1179435A (en) * 1966-06-17 1970-01-28 Ortho Pharma Corp Stable Reagent for the Detection of Rheumatoid Arthritis
US3925018A (en) * 1973-06-08 1975-12-09 Technicon Instr Method and apparatus for quantitative analysis utilizing particulate reagent material
US4035316A (en) * 1975-11-24 1977-07-12 California Institute Of Technology Cell specific, variable density, polymer microspheres
US4143203A (en) * 1976-03-19 1979-03-06 Amicon Corporation Particulate support material
IT1087285B (it) * 1976-11-10 1985-06-04 Hoffmann La Roche Procedimento di determinazione immunologico
GB1590525A (en) * 1976-12-10 1981-06-03 Technicon Instr Biological analysis
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US4191739A (en) * 1977-10-17 1980-03-04 General Electric Company Antigen-antibody reaction assay employing particle aggregation and resistive pulse analysis

Also Published As

Publication number Publication date
JPS6314783B2 (es) 1988-04-01
ES491029A0 (es) 1981-11-01
ES498270A0 (es) 1981-12-01
DE3071183D1 (en) 1985-11-21
DK198380A (da) 1980-11-08
EP0019741A1 (de) 1980-12-10
AU527485B2 (en) 1983-03-03
ATE16130T1 (de) 1985-11-15
DK153589C (da) 1988-12-12
AU5813080A (en) 1980-11-13
DK153589B (da) 1988-07-25
US4305925A (en) 1981-12-15
DE2918342A1 (de) 1980-11-20
JPS55151264A (en) 1980-11-25
ES8200770A1 (es) 1981-11-01
EP0019741B1 (de) 1985-10-16

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19971001