ES8302019A1 - Procedimiento de preparacion de nuevos derivados de benzol-y &-hidroxibencilpenil-osidos. - Google Patents

Procedimiento de preparacion de nuevos derivados de benzol-y &-hidroxibencilpenil-osidos.

Info

Publication number
ES8302019A1
ES8302019A1 ES506660A ES506660A ES8302019A1 ES 8302019 A1 ES8302019 A1 ES 8302019A1 ES 506660 A ES506660 A ES 506660A ES 506660 A ES506660 A ES 506660A ES 8302019 A1 ES8302019 A1 ES 8302019A1
Authority
ES
Spain
Prior art keywords
group
carbon atoms
derivatives
benzoyl
phenyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES506660A
Other languages
English (en)
Other versions
ES506660A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SORI SOC RECH IND
Original Assignee
SORI SOC RECH IND
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SORI SOC RECH IND filed Critical SORI SOC RECH IND
Publication of ES8302019A1 publication Critical patent/ES8302019A1/es
Publication of ES506660A0 publication Critical patent/ES506660A0/es
Granted legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20Carbocyclic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20Carbocyclic rings
    • C07H15/203Monocyclic carbocyclic rings other than cyclohexane rings; Bicyclic carbocyclic ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Genetics & Genomics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE DERIVADOS DE BENZOIL- Y <007>-HIDROXIBENCILFENIL-OXIDOS, DE FORMULA (I), Y DE SUS DIATEROISOMEROS CUANDO Z ES CHOH, DE FORMULA (I), EN LA QUE Z ES CO O CHOH; R ES UN RADICAL OXO; Y X -X PUEDEN SER VARIOS RADICALES. CONSISTE EN LA REACCION DE UN DERIVADO DE FENILFENOL DE FORMULA (II), EN LA QUE A ES HIDROGENO, SODIO O POTASIO, Y LOS DEMAS SIMBOLOS TIENEN EL MISMO SIGNIFICADO QUE EN LA FORMULA (I), CON UN DERIVADO OXO, TAL COMO HALOGENOACILOXOS O ACILOXOS. LA REACCION SE LLEVA A CABO EN UN DISOLVENTE INERTE, A UNA TEMPERATURA ENTRE 0<025>C Y LA DE REFLUJO DEL MEDIO DE REACCION. ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS COMO AGENTES ANTIULCEROSOS, ANTIAGREGANTES PLAQUETARIOS, ANTITROMBOTICOS Y OXIGENADORES CEREBRALES.
ES506660A 1980-10-29 1981-10-28 Procedimiento de preparacion de nuevos derivados de benzol-y &-hidroxibencilpenil-osidos. Granted ES506660A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8023133A FR2492830A1 (fr) 1980-10-29 1980-10-29 Nouveaux composes appartenant a la famille des benzoyl- et a-hydroxybenzyl-phenyl-osides, leur procede de preparation et leur application en therapeutique

Publications (2)

Publication Number Publication Date
ES8302019A1 true ES8302019A1 (es) 1983-01-01
ES506660A0 ES506660A0 (es) 1983-01-01

Family

ID=9247461

Family Applications (1)

Application Number Title Priority Date Filing Date
ES506660A Granted ES506660A0 (es) 1980-10-29 1981-10-28 Procedimiento de preparacion de nuevos derivados de benzol-y &-hidroxibencilpenil-osidos.

Country Status (14)

Country Link
US (1) US4432973A (es)
EP (1) EP0051023B1 (es)
JP (1) JPS57102899A (es)
KR (1) KR870001926B1 (es)
AT (1) ATE7701T1 (es)
CA (1) CA1181745A (es)
CS (1) CS224629B2 (es)
DD (1) DD202157A5 (es)
DE (1) DE3163912D1 (es)
ES (1) ES506660A0 (es)
FR (1) FR2492830A1 (es)
GR (1) GR75759B (es)
HU (1) HU191341B (es)
ZA (1) ZA817314B (es)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2549476B1 (fr) * 1983-07-20 1986-04-25 Rech Ind Benzyl-phenyl-osides, procede de preparation et utilisation en therapeutique
JPS63215688A (ja) * 1987-03-04 1988-09-08 Jujo Paper Co Ltd フェノ−ル配糖体の製造法
US4960758A (en) * 1987-05-04 1990-10-02 Fournier Innovation Et Synergie Novel β-D-phenylthioxylosides, their method of preparation and their use as pharmaceuticals
FR2614893B1 (fr) * 1987-05-04 1989-12-22 Fournier Innovation Synergie Nouveaux b-d-phenyl-thioxylosides, leur procede de preparation et leur application en therapeutique
FR2614894B1 (fr) * 1987-05-06 1989-06-16 Adir Nouvelles oximes derivees de la tylosine, leur procede de preparation et les compositions pharmaceutiques les contenant
IE63544B1 (en) * 1988-10-18 1995-05-17 Fournier Ind & Sante Novel Beta-d-phenylthioxylosides their method of preparation and their use in therapy
FR2652353B1 (fr) * 1989-09-22 1994-02-11 Fournier Industrie Sante Nouveaux benzopyran-2-one-beta-d-thioxylosides, leur procede de preparation et leur utilisation en therapeutique.
EP0421829B1 (fr) * 1989-09-22 1994-11-09 Fournier Industrie Et Sante Nouveaux benzopyranone-beta-D-thioxylosides, leur procédé de préparation et leur utilisation en thérapeutique
HK1039128A1 (zh) * 1998-06-24 2002-04-12 弗尼亚工业和卫生 从α-D-木糖衍生的新化合物,制备方法和治疗用途
US6680344B1 (en) 1999-06-01 2004-01-20 The University Of Texas Southwestern Medical Center Method of treating hair loss using diphenylmethane derivatives
AR018699A1 (es) 1999-06-01 2001-11-28 Procter & Gamble Metodo para el tratamiento de la perdida del cabello el cual comprende administrar una composicion que comprende un compuesto el cual no afecta al corazon
JP2003500432A (ja) 1999-06-01 2003-01-07 ザ・ユニバーシティ・オブ・テキサス・サウスウエスタン・メディカル・センター ジフェニルエーテル誘導体を用いて脱毛症を処置する方法
US6291433B1 (en) 1999-06-11 2001-09-18 Fournier Industrie Et Sante Derivatives of α-D-Thioxyloside and their use against atheroma
FR2802929B1 (fr) * 1999-12-23 2003-06-06 Fournier Ind & Sante Benzophenone alpha-d-glycopyranosides, preparation et utilisation en therapeutique
FR2802930B1 (fr) * 1999-12-23 2003-10-10 Fournier Ind & Sante Benzophenone glycopyranosides, preparation et utilisation en therapeutique
HK1052183A1 (zh) * 2000-03-10 2003-09-05 Pharmacia Corporation 制造tetrahydrobenzothiepines的方法
FR2826367B1 (fr) * 2001-06-21 2004-01-30 Fournier Lab Sa Nouveaux derives de [4-(4-cyanobenzoyl)phenyl] glycopyranoside, utilisation en tant que medicamment, procede d'obtention et compositions pharmaceutiques les contenant
FR2826368B1 (fr) * 2001-06-21 2004-01-30 Fournier Lab Sa Nouveaux derives de [4-(4-cyanobenzoyl)phenyl] glycofuranoside, utilisation en tant que medicamment, procede d'obtention et compositions pharmaceutiques les contenant
FR2860234B1 (fr) 2003-09-25 2005-12-23 Fournier Lab Sa Nouveaux derives 666 du thioxylose
JP4753022B2 (ja) * 2004-02-17 2011-08-17 独立行政法人産業技術総合研究所 プリオン増殖抑制剤
JPWO2007013694A1 (ja) * 2005-07-29 2009-02-12 武田薬品工業株式会社 フェノキシアルカン酸化合物
FR2903698B1 (fr) 2006-07-13 2009-01-30 Fournier S A Sa Lab Nouveaux derives de 5-thioxylopyranose.
FR2906247B1 (fr) * 2006-09-27 2008-12-26 Fournier S A Sa Lab Nouveaux derives de 5-thioxylopyranose
FR2906248B1 (fr) 2006-09-27 2008-12-26 Fournier S A Sa Lab Nouveaux derives de 5-thioxylopyranose

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2218569A (en) * 1939-09-13 1940-10-22 Dow Chemical Co Glycosides of pentose ethers
US2798079A (en) * 1953-12-29 1957-07-02 Universal Oil Prod Co Condensation of aromatic hydrocarbon derivatives with carbohydrates and related materials
US3152115A (en) * 1960-11-17 1964-10-06 Geigy Chem Corp New aryl glucosaminides
US3356674A (en) * 1961-07-07 1967-12-05 Rikagaku Kenkyusho 3-c-hydroxymethyl-3, 5-didesoxy-l-lyxofuranose and its derivatives, and a process for the production thereof
US3496196A (en) * 1965-10-02 1970-02-17 Tanabe Pharm Co Ltd 4,6-diazido-4,6-dideoxy-myo-inositol tetraacylates
FR2141532B1 (es) * 1971-06-14 1974-08-23 Anvar
US3960835A (en) * 1974-01-18 1976-06-01 Commercial Solvents Corporation Zearaline glycoside compounds
US4175123A (en) * 1976-12-23 1979-11-20 Bayer Aktiengesellschaft Amino-sugar derivatives, process for their preparation and pharmaceutical composition thereof

Also Published As

Publication number Publication date
ZA817314B (en) 1982-10-27
ES506660A0 (es) 1983-01-01
DE3163912D1 (en) 1984-07-05
KR870001926B1 (ko) 1987-10-22
EP0051023B1 (fr) 1984-05-30
FR2492830A1 (fr) 1982-04-30
HU191341B (en) 1987-02-27
KR830007485A (ko) 1983-10-21
JPS57102899A (en) 1982-06-26
DD202157A5 (de) 1983-08-31
US4432973A (en) 1984-02-21
CA1181745A (en) 1985-01-29
ATE7701T1 (de) 1984-06-15
GR75759B (es) 1984-08-02
FR2492830B1 (es) 1983-10-07
EP0051023A1 (fr) 1982-05-05
CS224629B2 (en) 1984-01-16
JPH024235B2 (es) 1990-01-26

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19970303