ES8302311A1 - Metodo para la determinacion de un analito biologico de interes utilizando agentes pluorescentes encapsulados. - Google Patents
Metodo para la determinacion de un analito biologico de interes utilizando agentes pluorescentes encapsulados.Info
- Publication number
- ES8302311A1 ES8302311A1 ES506017A ES506017A ES8302311A1 ES 8302311 A1 ES8302311 A1 ES 8302311A1 ES 506017 A ES506017 A ES 506017A ES 506017 A ES506017 A ES 506017A ES 8302311 A1 ES8302311 A1 ES 8302311A1
- Authority
- ES
- Spain
- Prior art keywords
- immunoassay
- binding partner
- test kit
- analyte
- microencapsulated
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000003018 immunoassay Methods 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title abstract 2
- 239000012491 analyte Substances 0.000 abstract 3
- 239000000463 material Substances 0.000 abstract 3
- 238000000034 method Methods 0.000 abstract 2
- 230000003213 activating effect Effects 0.000 abstract 1
- 230000000984 immunochemical effect Effects 0.000 abstract 1
- 239000003094 microcapsule Substances 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/585—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with a particulate label, e.g. coloured latex
- G01N33/586—Liposomes, microcapsules or cells
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/80—Fluorescent dyes, e.g. rhodamine
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/805—Optical property
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/807—Apparatus included in process claim, e.g. physical support structures
- Y10S436/808—Automated or kit
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/826—Additives, e.g. buffers, diluents, preservatives
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Manufacturing Of Micro-Capsules (AREA)
Abstract
METODO PARA LA DETERMINACION DE UN ANALITO BIOLOGICO MEDIANTE AGENTES FLUORESCENTES ENCAPSULADOS. CONSISTE EN MARCAR UNA ESPECIE INMUNOLOGICA, ESPECIFICA PARA EL ANALITO, CON UN MATERIAL FLUORESCENTE ENCAPSULADO, BIOLOGICAMENTE COMPATIBLE CON DICHA ESPECIE; PONER EN CONTACTO LA ESPECIE MARCADA CON FLOURESCENTE ENCAPSULADO Y EL MATERIAL BIOLOGICO A ANALIZAR; SEPARAR EL COMPLEJO FORMADO; ROMPER LA CAPSULA QUE CONTIENE EL MARCADOR FLUORESCENTE; PONER EN CONTACTO EL FLUORESCENTE LIBERADO CON UNA FUENTE DE ENERGIA, QUE NO SEA RADIACION ELECTROMAGNETICA, Y CAPAZ DE ACTIVAR EL MARCADOR FLUORESCENTE; Y DETERMINAR LA QUIMILUMINISCENCIA EMITIDA. EL METODO TIENE APLICACIONES EN ANALISIS CLINICOS, CUALI Y CUANTITATIVOS.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/233,057 US4372745A (en) | 1979-12-19 | 1981-02-10 | Chemical luminescence amplification substrate system for immunochemistry involving microencapsulated fluorescer |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES506017A0 ES506017A0 (es) | 1983-01-01 |
| ES8302311A1 true ES8302311A1 (es) | 1983-01-01 |
Family
ID=22875705
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES506017A Expired ES8302311A1 (es) | 1981-02-10 | 1981-10-05 | Metodo para la determinacion de un analito biologico de interes utilizando agentes pluorescentes encapsulados. |
| ES515013A Expired ES8306260A1 (es) | 1981-02-10 | 1982-08-16 | "dispositivo para la determinacion de un analito biologico de interes utilizando agentes fluorescentes encapsulados". |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES515013A Expired ES8306260A1 (es) | 1981-02-10 | 1982-08-16 | "dispositivo para la determinacion de un analito biologico de interes utilizando agentes fluorescentes encapsulados". |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US4372745A (es) |
| EP (1) | EP0070832A4 (es) |
| BE (1) | BE892094R (es) |
| BR (1) | BR8108972A (es) |
| CA (1) | CA1190147A (es) |
| ES (2) | ES8302311A1 (es) |
| IT (1) | IT1157258B (es) |
| WO (1) | WO1982002772A1 (es) |
| ZA (1) | ZA82338B (es) |
Families Citing this family (96)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1201382A (en) * | 1982-03-26 | 1986-03-04 | Andrew S. Janoff | Lupus assay method and composition |
| JPS59500529A (ja) * | 1982-03-26 | 1984-03-29 | ザ リポソ−ム カンパニ−、インコ−ポレ−テッド | 狼瘡分析方法および組成物 |
| US4483929A (en) * | 1982-05-03 | 1984-11-20 | Liposome Technology Incorporated | Liposomes with glycolipid-linked antibodies |
| US4480041A (en) * | 1982-07-09 | 1984-10-30 | Collaborative Research, Inc. | Use of phosphotriester intermediates for preparation of functionalized liposomes |
| US4517303A (en) * | 1982-10-20 | 1985-05-14 | E. I. Du Pont De Nemours And Company | Specific binding assays utilizing analyte-cytolysin conjugates |
| US4668638A (en) * | 1983-03-24 | 1987-05-26 | The Liposome Company, Inc. | Liposome composition for lupus assay |
| JPH06105256B2 (ja) * | 1983-06-14 | 1994-12-21 | 株式会社東芝 | 免疫分析方法 |
| US4713324A (en) * | 1983-09-01 | 1987-12-15 | Technicon Instruments Corporation | Inverted latency specific binding assay |
| GB8401368D0 (en) * | 1984-01-19 | 1984-02-22 | Amersham Int Plc | Assay method |
| US4695554A (en) * | 1984-02-14 | 1987-09-22 | Becton Dickinson And Company | Sac or liposome containing dye (sulforhodamine) for immunoassay |
| US4708933A (en) * | 1984-06-12 | 1987-11-24 | Leaf Huang | Immunoliposome assay-methods and products |
| US4957735A (en) * | 1984-06-12 | 1990-09-18 | The University Of Tennessee Research Corporation | Target-sensitive immunoliposomes- preparation and characterization |
| US5082768A (en) * | 1984-06-15 | 1992-01-21 | Mast Immunosystems, Inc. | Attenuator to suppress extraneous light in luminescent specific-binding assays |
| US4814270A (en) * | 1984-09-13 | 1989-03-21 | Becton Dickinson And Company | Production of loaded vesicles |
| DK365785A (da) * | 1984-09-17 | 1986-03-18 | Hoffmann La Roche | Metalcomplexer |
| US5075447A (en) * | 1984-09-17 | 1991-12-24 | Hoffmann-La Roche Inc. | Ruthenium complexes useful as carriers for immunologically active materials |
| US5310687A (en) * | 1984-10-31 | 1994-05-10 | Igen, Inc. | Luminescent metal chelate labels and means for detection |
| US4743561A (en) * | 1985-03-05 | 1988-05-10 | Abbott Laboratories | Luminescent assay with a reagent to alter transmitive properties of assay solution |
| US4678608A (en) * | 1985-04-15 | 1987-07-07 | American Cyanamid Company | Chemiluminescent composition |
| JPS61277062A (ja) * | 1985-05-31 | 1986-12-08 | Hitachi Ltd | 免疫分析方法およびそれに用いる試薬 |
| US4752572A (en) * | 1985-08-30 | 1988-06-21 | Eastman Kodak Company | Lipid vesicles containing labeled species and their analytical uses |
| US5017475A (en) * | 1985-11-25 | 1991-05-21 | Microbiological Associates, Inc. | Fluorescent detection method based on enzyme activated conversion of a fluorophore precursor substrate |
| DE3545398A1 (de) * | 1985-12-20 | 1987-06-25 | Boehringer Mannheim Gmbh | Verfahren zur steigerung der quanten-ausbeute bei der oxidation von luminol durch peroxide in gegenwart von peroxidase |
| US4717511A (en) * | 1985-12-26 | 1988-01-05 | American Cyanamid Company | Chemiluminescent composition |
| US5585279A (en) * | 1986-01-23 | 1996-12-17 | Davidson; Robert S. | Time-resolved luminescence binding assays using a fluorescent transition metal label other than ruthenium |
| US4698183A (en) * | 1986-02-04 | 1987-10-06 | American Cyanamid Company | High light output-short duration chemiluminescent compositions |
| US6271041B1 (en) | 1986-04-30 | 2001-08-07 | Igen International, Inc. | Electrochemiluminescent reaction utilizing amine-derived reductant |
| US6165729A (en) * | 1986-04-30 | 2000-12-26 | Hyperion Catalysis International, Inc. | Electrochemiluminescent reaction utilizing amine-derived reductant |
| US6451225B1 (en) | 1986-04-30 | 2002-09-17 | Igen International, Inc. | Electrochemiluminescent reaction utilizing amine-derived reductant |
| US5707559A (en) * | 1986-07-17 | 1998-01-13 | Tropix, Inc. | Chemiluminescent 1,2-dioxetane compounds |
| BR8707399A (pt) | 1986-07-24 | 1988-09-13 | Quest Systems Inc | Metodo de detectar uma substancia usando decomposicao enzimaticamente induzida de dioxetanos |
| EP0261719A3 (en) * | 1986-09-23 | 1990-10-10 | Akzo N.V. | Thermochemiluminescent cyclodextrin complexes |
| US4891324A (en) * | 1987-01-07 | 1990-01-02 | Syntex (U.S.A.) Inc. | Particle with luminescer for assays |
| US4978625A (en) * | 1987-10-19 | 1990-12-18 | Becton, Dickinson And Company | Fluorescence immunoassay using water insoluble dyes |
| EP0674176B1 (en) | 1987-11-04 | 2004-02-04 | Igen International, Inc. | Luminescent rhenium complexes and methods of production |
| US4950613A (en) * | 1988-02-26 | 1990-08-21 | Gen-Probe Incorporated | Proteted chemiluminescent labels |
| US6702986B1 (en) | 1988-04-29 | 2004-03-09 | Igen International, Inc. | Electrochemiluminescent reaction utilizing amine-derived reductant |
| US5256532A (en) * | 1988-05-02 | 1993-10-26 | Zynaxis Technologies, Inc. | Methods, reagents and test kits for determination of subpopulations of biological entities |
| US5389523A (en) * | 1988-05-31 | 1995-02-14 | The United States Of Americas, As Represented By The Secretary Of Commerce | Liposome immunoanalysis by flow injection assay |
| JP2656564B2 (ja) * | 1988-08-26 | 1997-09-24 | 株式会社日立製作所 | 免疫分析方法 |
| US5238610A (en) * | 1988-10-06 | 1993-08-24 | The United States Of America As Represented By The Secretary Of The Navy | Method of detecting oxidizing agents in aqueous media through the use of chemiluminescent microemulsions |
| CA2002083C (en) * | 1988-11-03 | 2001-01-09 | Haresh P. Shah | Enhanced electrochemiluminescence |
| MY104234A (en) * | 1988-11-17 | 1994-02-28 | Becton Dickinson Co | Immunoassay on a preblocked solid surface |
| WO1991005063A1 (en) * | 1989-10-05 | 1991-04-18 | Exoxemis, Inc. | Haloperoxidase acid optimum chemiluminescence assay system |
| WO1991005605A1 (en) * | 1989-10-10 | 1991-05-02 | Kosak Kenneth M | Cyclodextrin labels for immunoassay and biochemical analysis |
| US5108899A (en) * | 1989-10-31 | 1992-04-28 | Exoxemis, Inc. | Chemiluminescence assay of in vivo inflammation |
| US5375606A (en) * | 1990-02-28 | 1994-12-27 | Zynaxis, Inc. | Bio-analytical separation method |
| US5121302A (en) * | 1990-12-24 | 1992-06-09 | American Cyanamid Company | Solid, thin chemiluminescent device |
| JP3097866B2 (ja) * | 1991-10-15 | 2000-10-10 | マルティライト リミティド | 標識試薬を使用した結合検定法 |
| US6159686A (en) * | 1992-09-14 | 2000-12-12 | Sri International | Up-converting reporters for biological and other assays |
| US6399397B1 (en) | 1992-09-14 | 2002-06-04 | Sri International | Up-converting reporters for biological and other assays using laser excitation techniques |
| US5736410A (en) | 1992-09-14 | 1998-04-07 | Sri International | Up-converting reporters for biological and other assays using laser excitation techniques |
| US5437274A (en) * | 1993-02-25 | 1995-08-01 | Gholam A. Peyman | Method of visualizing submicron-size vesicles and particles in blood circulation |
| AU687363B2 (en) * | 1993-03-19 | 1998-02-26 | Ciba Corning Diagnostics Corp. | Luminometer |
| GB9310468D0 (en) * | 1993-05-20 | 1993-07-07 | Oxford Glycosystems Ltd | Sugar complexes |
| US6316180B1 (en) | 1995-01-04 | 2001-11-13 | Igen International, Inc. | Electrochemiluminescent monitoring of compounds/electrochemiluminescence assays |
| US5643713A (en) * | 1995-06-07 | 1997-07-01 | Liang; Pam | Electrochemiluminescent monitoring of compounds |
| US20010003647A1 (en) * | 1995-06-07 | 2001-06-14 | Ji Sun | Coreatant-including electrochemiluminescent compounds, methods, systems and kits utilizing same |
| WO1996033411A1 (en) * | 1995-04-18 | 1996-10-24 | Igen, Inc. | Electrochemiluminescence of rare earth metal chelates |
| CN1181720A (zh) * | 1995-04-25 | 1998-05-13 | 伊萝莉公司 | 可远程编程的存储器材料及其应用 |
| US5679519A (en) * | 1995-05-09 | 1997-10-21 | Oprandy; John J. | Multi-label complex for enhanced sensitivity in electrochemiluminescence assay |
| US6319670B1 (en) * | 1995-05-09 | 2001-11-20 | Meso Scale Technology Llp | Methods and apparatus for improved luminescence assays using microparticles |
| US5686046A (en) * | 1995-07-13 | 1997-11-11 | Chiron Diagnostics Corporation | Luminometer |
| US5856194A (en) | 1996-09-19 | 1999-01-05 | Abbott Laboratories | Method for determination of item of interest in a sample |
| US5795784A (en) | 1996-09-19 | 1998-08-18 | Abbott Laboratories | Method of performing a process for determining an item of interest in a sample |
| US5800999A (en) | 1996-12-16 | 1998-09-01 | Tropix, Inc. | Dioxetane-precursor-labeled probes and detection assays employing the same |
| US7745142B2 (en) * | 1997-09-15 | 2010-06-29 | Molecular Devices Corporation | Molecular modification assays |
| US7632651B2 (en) * | 1997-09-15 | 2009-12-15 | Mds Analytical Technologies (Us) Inc. | Molecular modification assays |
| US7070921B2 (en) | 2000-04-28 | 2006-07-04 | Molecular Devices Corporation | Molecular modification assays |
| US20050227294A1 (en) * | 1997-09-15 | 2005-10-13 | Molecular Devices Corporation | Molecular modification assays involving lipids |
| DE69836092T2 (de) * | 1997-10-24 | 2007-05-10 | Invitrogen Corp., Carlsbad | Rekombinatorisches klonieren unter verwendung von nukleinsaüren mit rekombinationsstellen |
| CA2283597C (en) | 1998-10-02 | 2008-02-05 | Ortho-Clinical Diagnostics, Inc. | Reduced cortisol conjugates |
| US6410255B1 (en) * | 1999-05-05 | 2002-06-25 | Aurora Biosciences Corporation | Optical probes and assays |
| US7198924B2 (en) | 2000-12-11 | 2007-04-03 | Invitrogen Corporation | Methods and compositions for synthesis of nucleic acid molecules using multiple recognition sites |
| DE60137953D1 (de) | 2000-10-06 | 2009-04-23 | Life Technologies Corp | Zellen mit spektraler signatur sowie verfahren zu ihrer herstellung und nutzung |
| US6939721B2 (en) * | 2000-12-18 | 2005-09-06 | Agilent Technologies, Inc. | Fluorescence immunoassays using organo-metallic complexes for energy transfer |
| US6461543B2 (en) * | 2001-01-17 | 2002-10-08 | Omniglow Corporation | Chemiluminescent solution based on disubstituted perylene tetracarboxylic acids, their dianhydrides and diimides |
| US7727752B2 (en) * | 2003-07-29 | 2010-06-01 | Life Technologies Corporation | Kinase and phosphatase assays |
| CA2445420A1 (en) * | 2003-07-29 | 2005-01-29 | Invitrogen Corporation | Kinase and phosphatase assays |
| US7619059B2 (en) * | 2003-07-29 | 2009-11-17 | Life Technologies Corporation | Bimolecular optical probes |
| US20050069929A1 (en) | 2003-08-08 | 2005-03-31 | Invitrogen Corporation | Methods and compositions for seamless cloning of nucleic acid molecules |
| US20060035242A1 (en) | 2004-08-13 | 2006-02-16 | Michelitsch Melissa D | Prion-specific peptide reagents |
| DE602004025592D1 (de) * | 2003-09-12 | 2010-04-01 | Life Technologies Corp | Anwendungen des Resonanzenergietransfers zwischen Terbium und GFP |
| WO2005043125A2 (en) * | 2003-11-03 | 2005-05-12 | Integrigen, Inc. | A non-fluorescent, non-enzymatic, chemiluminescent aqueous assay |
| DE602004027538D1 (de) * | 2003-12-01 | 2010-07-15 | Life Technologies Corp | Rekombinationsstellen enthaltende nukleinsäuremoleküle und verfahren zur verwendung davon |
| WO2005084404A2 (en) * | 2004-03-03 | 2005-09-15 | Cornell Research Foundation, Inc. | Microfluidic biosensor and methods of use |
| US8029985B2 (en) * | 2004-09-01 | 2011-10-04 | Vybion, Inc. | Amplified bioassay |
| TW200643171A (en) | 2005-06-07 | 2006-12-16 | Temasek Life Sciences Lab Ltd | Porcine circovirus type 2 vaccines |
| EP3211011A1 (en) | 2007-11-16 | 2017-08-30 | Nuvelo, Inc. | Antibodies to lrp6 |
| US20120107834A1 (en) * | 2009-01-16 | 2012-05-03 | Angros Lee H | Encapsulated reagents and methods of use |
| WO2013138522A2 (en) | 2012-03-16 | 2013-09-19 | Genelux Corporation | Methods for assessing effectiveness and monitoring oncolytic virus treatment |
| CN105122044B (zh) * | 2013-04-18 | 2018-01-02 | 英派尔科技开发有限公司 | 标记和检测石墨烯层中的缺陷的方法和系统 |
| US20190030153A1 (en) | 2015-07-22 | 2019-01-31 | University Of Saskatchewan | Mycoplasma vaccines and uses thereof |
| US20180258473A1 (en) * | 2015-11-10 | 2018-09-13 | Administracion General De La Comunidad Autonoma De Euskadi | Diagnostic methods and devices |
| US20210147525A1 (en) | 2019-10-18 | 2021-05-20 | The Regents Of The University Of California | Methods and compositions for treating pathogenic blood vessel disorders |
| EP4770666A2 (en) | 2023-09-01 | 2026-07-08 | Children's Hospital Medical Center | Identification of targets for immunotherapy in melanoma using splicing-derived neoantigens |
Family Cites Families (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3401123A (en) * | 1961-03-15 | 1968-09-10 | Ncr Co | Process for making case-hardened capsules and its capsule product |
| NL152290B (nl) * | 1965-09-08 | 1977-02-15 | American Cyanamid Co | Werkwijze ter bereiding van chemiluminescerende mengsels. |
| GB1270999A (en) * | 1969-07-30 | 1972-04-19 | Bdh Pharmaceuticals Ltd | Propane-1,2-diol derivatives |
| US3704231A (en) * | 1971-02-16 | 1972-11-28 | American Cyanamid Co | Chemiluminescent additives |
| US3817837A (en) * | 1971-05-14 | 1974-06-18 | Syva Corp | Enzyme amplification assay |
| US3887698A (en) * | 1973-03-12 | 1975-06-03 | Univ Leland Stanford Junior | Sacs with epitopic sites on walls enclosing stable free radicals |
| US3935074A (en) * | 1973-12-17 | 1976-01-27 | Syva Company | Antibody steric hindrance immunoassay with two antibodies |
| GB1461877A (en) | 1974-02-12 | 1977-01-19 | Wellcome Found | Assay method utilizing chemiluminescence |
| US4199559A (en) * | 1974-08-12 | 1980-04-22 | Syva Company | Fluorescence quenching with immunological pairs in immunoassays |
| US4169137A (en) * | 1974-12-20 | 1979-09-25 | Block Engineering, Inc. | Antigen detecting reagents |
| US4011219A (en) * | 1975-03-28 | 1977-03-08 | Chugai Seiyaku Kabushiki Kaisha | Phthalazine derivatives and salts thereof |
| US4018884A (en) * | 1975-06-26 | 1977-04-19 | Hoffmann-La Roche Inc. | Fluorogenic materials and labeling techniques |
| US4181650A (en) * | 1975-08-25 | 1980-01-01 | Maier Charles L Jr | Procedure for the assay of pharmacologically immunologically and biochemically active compounds in biological fluids |
| US4201763A (en) * | 1975-10-09 | 1980-05-06 | Bio-Rad Laboratories, Inc. | Solid phase immunofluorescent assay method |
| US4036946A (en) * | 1975-10-20 | 1977-07-19 | Marcos Kleinerman | Immunofluorometric method for measuring minute quantities of antigens, antibodies and other substances |
| US4020151A (en) * | 1976-02-17 | 1977-04-26 | International Diagnostic Technology, Inc. | Method for quantitation of antigens or antibodies on a solid surface |
| US4160818A (en) * | 1976-04-15 | 1979-07-10 | Technicon Instruments Corporation | Fluorimetric immunoassay for diphenylhydantoin |
| US4326008A (en) * | 1976-08-27 | 1982-04-20 | California Institute Of Technology | Protein specific fluorescent microspheres for labelling a protein |
| US4235792A (en) * | 1977-04-14 | 1980-11-25 | The Governing Council Of The University Of Toronto | Immunological materials |
| GB2008247B (en) * | 1977-11-17 | 1982-12-15 | Welsh Nat School Med | Detecting or quantifying substances using labelling techniques |
| US4235871A (en) * | 1978-02-24 | 1980-11-25 | Papahadjopoulos Demetrios P | Method of encapsulating biologically active materials in lipid vesicles |
| US4277437A (en) * | 1978-04-05 | 1981-07-07 | Syva Company | Kit for carrying out chemically induced fluorescence immunoassay |
| US4193983A (en) * | 1978-05-16 | 1980-03-18 | Syva Company | Labeled liposome particle compositions and immunoassays therewith |
| US4255411A (en) * | 1978-11-27 | 1981-03-10 | Damon Corporation | Process of determining an immunogenic substance by competition with an antibody in a microcapsule |
| US4241046A (en) * | 1978-11-30 | 1980-12-23 | Papahadjopoulos Demetrios P | Method of encapsulating biologically active materials in lipid vesicles |
| DE3000483A1 (de) * | 1979-01-09 | 1980-07-17 | Fuji Photo Film Co Ltd | Mikrokapseln fuer immunologische bestimmungen |
| US4238195A (en) * | 1979-01-18 | 1980-12-09 | Miles Laboratories, Inc. | Fluorescer-labeled specific binding assays |
| US4280816A (en) * | 1979-10-25 | 1981-07-28 | Nasik Elahi | Macroencapsulated immunosorbent assay technique and element therefor |
| WO1981001883A1 (en) * | 1979-12-19 | 1981-07-09 | Electro Nucleonics | Chemical luminescence amplification substrate system for immunochemistry |
| US4342826A (en) * | 1980-02-04 | 1982-08-03 | Collaborative Research, Inc. | Immunoassay products and methods |
-
1981
- 1981-02-10 US US06/233,057 patent/US4372745A/en not_active Expired - Fee Related
- 1981-09-21 BR BR8108972A patent/BR8108972A/pt unknown
- 1981-09-21 WO PCT/US1981/001286 patent/WO1982002772A1/en not_active Ceased
- 1981-09-21 EP EP19810902790 patent/EP0070832A4/en not_active Withdrawn
- 1981-10-05 ES ES506017A patent/ES8302311A1/es not_active Expired
-
1982
- 1982-01-18 CA CA000394331A patent/CA1190147A/en not_active Expired
- 1982-01-19 ZA ZA82338A patent/ZA82338B/xx unknown
- 1982-02-10 IT IT19574/82A patent/IT1157258B/it active
- 1982-02-10 BE BE0/207284A patent/BE892094R/fr active
- 1982-08-16 ES ES515013A patent/ES8306260A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| IT1157258B (it) | 1987-02-11 |
| ES506017A0 (es) | 1983-01-01 |
| CA1190147A (en) | 1985-07-09 |
| EP0070832A4 (en) | 1983-06-17 |
| BR8108972A (pt) | 1983-01-11 |
| WO1982002772A1 (en) | 1982-08-19 |
| ZA82338B (en) | 1982-11-24 |
| ES515013A0 (es) | 1983-05-01 |
| IT8219574A0 (it) | 1982-02-10 |
| BE892094R (fr) | 1982-08-10 |
| ES8306260A1 (es) | 1983-05-01 |
| EP0070832A1 (en) | 1983-02-09 |
| US4372745A (en) | 1983-02-08 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ES8306260A1 (es) | "dispositivo para la determinacion de un analito biologico de interes utilizando agentes fluorescentes encapsulados". | |
| AU564381B2 (en) | Non-fluorescent vessels for holding test samples in fluorescent assays | |
| NO903124D0 (no) | Testmetode og reagenssett for denne. | |
| JPS6447952A (en) | Immunoassay, reagent used therefor and making thereof | |
| ATE58600T1 (de) | Testverfahren. | |
| AU1591888A (en) | Element and method for performing biological assays accurately, rapidly and simply | |
| CA2005564A1 (en) | Test carrier for the analytical investigation of a sample liquid with the help of a specific binding reaction of two bioaffine binding partners and a corresponding test process | |
| ES8801440A1 (es) | Un metodo de ensayo mejorado para la determinacion de analitos bioligicos tales como haptenos, antigenos ,receptores , farmacos y similares. | |
| EP0291194B8 (en) | Immunoassays and devices therefor | |
| FI891012A0 (fi) | Menetelmä ja väline immuunikokeissa esiintyvien häiriötekijöiden kompensoimiseksi | |
| DK212986A (da) | Fremgangsmaade til bestemmelse af et stof i en praeve | |
| EP0217403A3 (en) | Solid-phase analytical device and method for using same | |
| ES8301367A1 (es) | Un metodo para realizar un ensayo de ligandos en un medio poroso inerte. | |
| JPS5763454A (en) | Immuno assay method and assay apparatus | |
| ES8302313A1 (es) | "metodo para ensayar reacciones antigeno-anticuerpo". | |
| ES2033266T3 (es) | Procedimiento y estuche de ensayo para la determinacion de sustancias activas libres en liquidos biologicos. | |
| GR3002496T3 (en) | Immunometric assay | |
| EP0303229A3 (en) | Method of high sensitivity immunoassay | |
| GB8626767D0 (en) | Assays | |
| JPS5748658A (en) | Immunologic measuring method and reagent for measurement | |
| MY103022A (en) | Monoclonal antibodies recognizing l-thyroxine | |
| DK72082A (da) | Cytoreceptor-proeve | |
| GB1508133A (en) | Biological analysis | |
| ATE80948T1 (de) | Diagnostisches immuntest-verfahren mittels festphasenabscheidung. | |
| GB8724549D0 (en) | Immunoassay |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 19981103 |