ES8306734A1 - "procedimiento para la preparacion de derivados de bis-aminometil-antraquinona". - Google Patents

"procedimiento para la preparacion de derivados de bis-aminometil-antraquinona".

Info

Publication number
ES8306734A1
ES8306734A1 ES516225A ES516225A ES8306734A1 ES 8306734 A1 ES8306734 A1 ES 8306734A1 ES 516225 A ES516225 A ES 516225A ES 516225 A ES516225 A ES 516225A ES 8306734 A1 ES8306734 A1 ES 8306734A1
Authority
ES
Spain
Prior art keywords
formula
bis
aminomethyl
manufacture
treatment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES516225A
Other languages
English (en)
Other versions
ES516225A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19803044072 external-priority patent/DE3044072A1/de
Priority claimed from DE19813117984 external-priority patent/DE3117984A1/de
Application filed by Hoechst AG filed Critical Hoechst AG
Publication of ES516225A0 publication Critical patent/ES516225A0/es
Publication of ES8306734A1 publication Critical patent/ES8306734A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/10—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms
    • C07D295/112—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • C07D295/116—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings with the doubly bound oxygen or sulfur atoms directly attached to a carbocyclic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C46/00—Preparation of quinones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C50/00—Quinones
    • C07C50/24—Quinones containing halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C50/00—Quinones
    • C07C50/26—Quinones containing groups having oxygen atoms singly bound to carbon atoms
    • C07C50/34—Quinones containing groups having oxygen atoms singly bound to carbon atoms the quinoid structure being part of a condensed ring system having three rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/10—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms
    • C07D211/14—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms with hydrocarbon or substituted hydrocarbon radicals attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/26—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE DERIVADOS DE BIS-AMINOMETILANTRAQUINONA Y DE SUS SALES CON ACIDOS FISIOLOGICAMENTE COMPATIBLES, DE FORMULA (I), EN LA QUE R Y R PUEDEN SER VARIOS TIPOS DE RADICALES; Y R PUEDE SER HIDROGENO O HIDROXILO. CONSISTE EN LA REACCION DE REDUCCION DE UNA ANTRAQUINONA DE FORMULA (II); SEGUIDA DE TRATAMIENTO DE LA ANTRAHIDROQUINONA FORMADA CON FORMALDEHIDO Y UNA AMINA DE FORMULA R NHR , EN LA QUE R Y R TIENEN EL MISMO SIGNIFICADO QUE EN LA FORMULA (I); Y, FINALMENTE, OXIDACION DEL DERIVADO DE BIS-AMINOMETILANTRAHIDROQUINONA OBTENIDO CON OXIGENO, PEROXIDO DE HIDROGENO O PEROXIACIDOS. LA REDUCCION SE LLEVA A CABO CON DITIONITRO SODICO, MEDIANTE HIDROGENACION CATALITICA O CON HIDRUROS METALICOS. ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS PARA EL TRATAMIENTO DE AMEBIASIS, ENFERMEDADES CANCEROSAS Y VIRICAS Y CONTRA LA ENCEFALOMIOCARDITIS.
ES516225A 1980-11-24 1982-10-05 "procedimiento para la preparacion de derivados de bis-aminometil-antraquinona". Expired ES8306734A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19803044072 DE3044072A1 (de) 1980-11-24 1980-11-24 Bis-aminomehtyl-anthrachinon-derivate, verfahren zu ihrer herstellung, sie enthaltende mittel und ihre verwendung
DE19813117984 DE3117984A1 (de) 1981-05-07 1981-05-07 Bis-(aminomethyl)-anthrachinon-derivate, verfahren zu ihrer herstellung, sie enthaltende mittel und ihre verwendung

Publications (2)

Publication Number Publication Date
ES516225A0 ES516225A0 (es) 1983-06-01
ES8306734A1 true ES8306734A1 (es) 1983-06-01

Family

ID=25789259

Family Applications (2)

Application Number Title Priority Date Filing Date
ES507234A Granted ES507234A0 (es) 1980-11-24 1981-11-18 Procedimiento para la preparacion de derivados de bis-amino-metil-antraquinona.
ES516225A Expired ES8306734A1 (es) 1980-11-24 1982-10-05 "procedimiento para la preparacion de derivados de bis-aminometil-antraquinona".

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES507234A Granted ES507234A0 (es) 1980-11-24 1981-11-18 Procedimiento para la preparacion de derivados de bis-amino-metil-antraquinona.

Country Status (10)

Country Link
EP (1) EP0052853A1 (es)
AR (1) AR227341A1 (es)
AU (1) AU7776681A (es)
DK (1) DK519581A (es)
ES (2) ES507234A0 (es)
FI (1) FI813709A7 (es)
GR (1) GR78224B (es)
IL (1) IL64336A0 (es)
NO (1) NO813974L (es)
PT (1) PT74023B (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AUPR393701A0 (en) * 2001-03-23 2001-04-26 Commonwealth Scientific And Industrial Research Organisation Self-reducing anthraquinone compounds
ES2496592T3 (es) 2006-11-16 2014-09-19 F.I.S.- Fabbrica Italiana Sintetici S.P.A. Proceso para la preparación de Imatinib y compuestos intermedios del mismo
WO2016116527A1 (de) * 2015-01-20 2016-07-28 Cynora Gmbh Organische moleküle, insbesondere zur verwendung in optoelektronischen bauelementen

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2055111A1 (en) * 1970-11-10 1972-05-18 Bredereck, Karl, Dr., 7000 Stuttgart Aminomethylation of aminoanthraquinones - to yield dyestuff inters
SE445996B (sv) * 1977-08-15 1986-08-04 American Cyanamid Co Nya atrakinonderivat
DE2827197A1 (de) * 1978-06-21 1980-01-10 Bayer Ag Verfahren zur herstellung von aminoanthrachinonen

Also Published As

Publication number Publication date
GR78224B (es) 1984-09-26
ES8303385A1 (es) 1983-02-01
AU7776681A (en) 1982-06-03
ES516225A0 (es) 1983-06-01
PT74023B (de) 1983-08-16
FI813709L (fi) 1982-05-25
FI813709A7 (fi) 1982-05-25
DK519581A (da) 1982-05-25
AR227341A1 (es) 1982-10-15
NO813974L (no) 1982-05-25
EP0052853A1 (de) 1982-06-02
IL64336A0 (en) 1982-02-28
ES507234A0 (es) 1983-02-01
PT74023A (de) 1981-12-01

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