ES8307723A1 - "procedimiento para la preparacion de nuevos 1-ariloxi-3-alcohilamino-2-propanoles". - Google Patents
"procedimiento para la preparacion de nuevos 1-ariloxi-3-alcohilamino-2-propanoles".Info
- Publication number
- ES8307723A1 ES8307723A1 ES515245A ES515245A ES8307723A1 ES 8307723 A1 ES8307723 A1 ES 8307723A1 ES 515245 A ES515245 A ES 515245A ES 515245 A ES515245 A ES 515245A ES 8307723 A1 ES8307723 A1 ES 8307723A1
- Authority
- ES
- Spain
- Prior art keywords
- formula
- procedure
- alcohilamino
- ariloxi
- propanols
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000000034 method Methods 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 206010002383 Angina Pectoris Diseases 0.000 abstract 1
- LFQSCWFLJHTTHZ-HQMMCQRPSA-N Ethanol-14C Chemical compound C[14CH2]O LFQSCWFLJHTTHZ-HQMMCQRPSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 230000000144 pharmacologic effect Effects 0.000 abstract 1
- 239000002798 polar solvent Substances 0.000 abstract 1
- 238000010992 reflux Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C253/00—Preparation of carboxylic acid nitriles
- C07C253/30—Preparation of carboxylic acid nitriles by reactions not involving the formation of cyano groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Cardiology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pyrrole Compounds (AREA)
- Fats And Perfumes (AREA)
- Medicinal Preparation (AREA)
- Saccharide Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
- Seasonings (AREA)
Abstract
PROCEDIMIENTO PARA LA OBTENCION DE 1-ARILOXI-3-ALCOHILAMINO-2-PROPANOLES Y DE SUS SALES DE ADICION DE ACIDO, DE FORMULA (I), EN LA QUE R<3 ES ALCOHILO C<1<-<1<0; Y R<1 Y R<2 PUEDEN SER VARIOS TIPOS DE RADICALES. CONSISTE EN LA REACCION DE UN COMPUESTO DE FORMULA (II) CON UNA AMINA DE FORMULA NH<2R<3, EN LAS QUE Z ES EL GRUPO -CH-CH<2- O -CHOH-CH<2-HAL, SIENDO HAL UN HALOGENO; Y R<1, R<2 Y R<3 TIENEN EL MISMO SIGNIFICADO QUE EN LA FORMULA (I). LA REACCION SE LLEVA A CABO EN UN DISOLVENTE POLAR, TAL COMO ETANOL, A LA TEMPERATURA DE REFLUJO. ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS PARA EL TRATAMIENTO DE LA ANGINA DE PECHO Y ARRITMIAS CARDIACAS.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19813133678 DE3133678A1 (de) | 1981-08-26 | 1981-08-26 | Neue l-aryloxy-3-alkylamino-2-propanole und verfahren zu ihrer herstellung |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES515245A0 ES515245A0 (es) | 1983-08-01 |
| ES8307723A1 true ES8307723A1 (es) | 1983-08-01 |
Family
ID=6140122
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES515245A Expired ES8307723A1 (es) | 1981-08-26 | 1982-08-25 | "procedimiento para la preparacion de nuevos 1-ariloxi-3-alcohilamino-2-propanoles". |
| ES520095A Expired ES8401455A1 (es) | 1981-08-26 | 1983-02-25 | Procedimiento para la preparacion de nuevos 1-ariloxi-3-alcohilamino-2-propanoles. |
| ES520094A Granted ES520094A0 (es) | 1981-08-26 | 1983-02-25 | Procedimiento para la preparacion de nuevos 1-ariloxi-3-alcohilamino-2-propanoles. |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES520095A Expired ES8401455A1 (es) | 1981-08-26 | 1983-02-25 | Procedimiento para la preparacion de nuevos 1-ariloxi-3-alcohilamino-2-propanoles. |
| ES520094A Granted ES520094A0 (es) | 1981-08-26 | 1983-02-25 | Procedimiento para la preparacion de nuevos 1-ariloxi-3-alcohilamino-2-propanoles. |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US4442120A (es) |
| EP (1) | EP0073016B1 (es) |
| JP (1) | JPS5859957A (es) |
| KR (1) | KR890000620B1 (es) |
| AT (1) | ATE16700T1 (es) |
| AU (1) | AU558338B2 (es) |
| CA (1) | CA1165324A (es) |
| DE (2) | DE3133678A1 (es) |
| DK (1) | DK380482A (es) |
| ES (3) | ES8307723A1 (es) |
| FI (1) | FI75150C (es) |
| GR (1) | GR77606B (es) |
| IE (1) | IE54224B1 (es) |
| IL (1) | IL66633A (es) |
| NO (1) | NO152603C (es) |
| NZ (1) | NZ201716A (es) |
| PH (1) | PH19705A (es) |
| PT (1) | PT75458A (es) |
| ZA (1) | ZA826183B (es) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6343516B1 (en) * | 1998-01-16 | 2002-02-05 | Texaco Inc. | Multiphase flow sampling using an autotraversing sample probe |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1199037A (en) * | 1967-09-27 | 1970-07-15 | Ici Ltd | Alkanolamine Derivatives |
| DE2503222A1 (de) * | 1975-01-27 | 1976-07-29 | Boehringer Sohn Ingelheim | Verfahren zur herstellung von 1-aryl- oxy-3-n-substituierten aminopropanderivaten |
| DE3015991A1 (de) * | 1980-04-25 | 1981-11-05 | C.H. Boehringer Sohn, 6507 Ingelheim | Neue 1-aryloxy-3-alkylamino-2-propanole und verfahren zur ihrer herstellung |
-
1981
- 1981-08-26 DE DE19813133678 patent/DE3133678A1/de not_active Withdrawn
-
1982
- 1982-06-29 NO NO822220A patent/NO152603C/no unknown
- 1982-07-15 US US06/398,577 patent/US4442120A/en not_active Expired - Fee Related
- 1982-07-22 PH PH27614A patent/PH19705A/en unknown
- 1982-07-26 CA CA000408021A patent/CA1165324A/en not_active Expired
- 1982-08-18 EP EP82107536A patent/EP0073016B1/de not_active Expired
- 1982-08-18 AT AT82107536T patent/ATE16700T1/de not_active IP Right Cessation
- 1982-08-18 DE DE8282107536T patent/DE3267692D1/de not_active Expired
- 1982-08-23 FI FI822912A patent/FI75150C/fi not_active IP Right Cessation
- 1982-08-24 PT PT75458A patent/PT75458A/pt unknown
- 1982-08-24 IL IL66633A patent/IL66633A/xx unknown
- 1982-08-25 GR GR69110A patent/GR77606B/el unknown
- 1982-08-25 JP JP57147518A patent/JPS5859957A/ja active Pending
- 1982-08-25 ZA ZA826183A patent/ZA826183B/xx unknown
- 1982-08-25 DK DK380482A patent/DK380482A/da not_active Application Discontinuation
- 1982-08-25 AU AU87718/82A patent/AU558338B2/en not_active Ceased
- 1982-08-25 KR KR8203820A patent/KR890000620B1/ko not_active Expired
- 1982-08-25 NZ NZ201716A patent/NZ201716A/en unknown
- 1982-08-25 IE IE2047/82A patent/IE54224B1/en unknown
- 1982-08-25 ES ES515245A patent/ES8307723A1/es not_active Expired
-
1983
- 1983-02-25 ES ES520095A patent/ES8401455A1/es not_active Expired
- 1983-02-25 ES ES520094A patent/ES520094A0/es active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| NZ201716A (en) | 1986-02-21 |
| KR840001129A (ko) | 1984-03-28 |
| AU558338B2 (en) | 1987-01-29 |
| IL66633A0 (en) | 1982-12-31 |
| PT75458A (de) | 1982-09-01 |
| ES8401454A1 (es) | 1983-12-01 |
| FI822912L (fi) | 1983-02-27 |
| EP0073016B1 (de) | 1985-11-27 |
| GR77606B (es) | 1984-09-25 |
| ES520094A0 (es) | 1983-12-01 |
| IE822047L (en) | 1983-02-26 |
| ES520095A0 (es) | 1983-12-01 |
| NO152603C (no) | 1985-10-23 |
| FI75150B (fi) | 1988-01-29 |
| ES8401455A1 (es) | 1983-12-01 |
| FI75150C (fi) | 1988-05-09 |
| DE3267692D1 (en) | 1986-01-09 |
| ES515245A0 (es) | 1983-08-01 |
| US4442120A (en) | 1984-04-10 |
| ATE16700T1 (de) | 1985-12-15 |
| EP0073016A1 (de) | 1983-03-02 |
| AU8771882A (en) | 1983-03-03 |
| IE54224B1 (en) | 1989-07-19 |
| NO822220L (no) | 1983-02-28 |
| NO152603B (no) | 1985-07-15 |
| IL66633A (en) | 1986-02-28 |
| JPS5859957A (ja) | 1983-04-09 |
| PH19705A (en) | 1986-06-16 |
| FI822912A0 (fi) | 1982-08-23 |
| DE3133678A1 (de) | 1983-03-17 |
| CA1165324A (en) | 1984-04-10 |
| KR890000620B1 (ko) | 1989-03-22 |
| ZA826183B (en) | 1984-04-25 |
| DK380482A (da) | 1983-02-27 |
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