ES8400382A1 - Un derivado de ascoclorina - Google Patents

Un derivado de ascoclorina

Info

Publication number
ES8400382A1
ES8400382A1 ES515648A ES515648A ES8400382A1 ES 8400382 A1 ES8400382 A1 ES 8400382A1 ES 515648 A ES515648 A ES 515648A ES 515648 A ES515648 A ES 515648A ES 8400382 A1 ES8400382 A1 ES 8400382A1
Authority
ES
Spain
Prior art keywords
substitute
core
contain
derivative
ascochlorine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES515648A
Other languages
English (en)
Other versions
ES515648A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chugai Pharmaceutical Co Ltd
Original Assignee
Chugai Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP14166081A external-priority patent/JPS5843938A/ja
Priority claimed from JP16882181A external-priority patent/JPS5869860A/ja
Application filed by Chugai Pharmaceutical Co Ltd filed Critical Chugai Pharmaceutical Co Ltd
Publication of ES515648A0 publication Critical patent/ES515648A0/es
Publication of ES8400382A1 publication Critical patent/ES8400382A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79—Acids; Esters
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/125—Saturated compounds having only one carboxyl group and containing ether groups, groups, groups, or groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C403/00—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
    • C07C403/14—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by doubly-bound oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C07C69/67—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of saturated acids
    • C07C69/708—Ethers
    • C07C69/712—Ethers the hydroxy group of the ester being etherified with a hydroxy compound having the hydroxy group bound to a carbon atom of a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79—Acids; Esters
    • C07D213/80—Acids; Esters in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

UN PROCEDIMIENTO PARA LA PREPARACION DE UN DERIVADO DE ASCOCLORINASE HACE REACCIONAR UNA SAL MONOMETALICA DE ASCOCLORINA (II) DONDE M ES UN METAL ALCALINO, CON EL COMPUESTO X-(CNK H2NK) COR DONDE X ES UN ATOMO DE HALOGENO Y NK ES UN NUMERO ENTERO DE 1 A 5. EL PRODUCTO OBTENIDO (I) PUEDE HIDROLIZARSE A CONTINUACION. R ES UN GRUPO HIDROXILO, ALCOXI INFERIOR, PIRIDILO, AMINO, FENOXIALQUILO QUE PUEDE CONTENER UN SUSTITUYENTE EN EL NUCLEO O FENILO QUE ASIMISMO PUEDE CONTENER UN SUSTITUYENTE EN EL NUCLEO
ES515648A 1981-09-10 1982-09-10 Un derivado de ascoclorina Expired ES8400382A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP14166081A JPS5843938A (ja) 1981-09-10 1981-09-10 アスコクロリン誘導体
JP16882181A JPS5869860A (ja) 1981-10-23 1981-10-23 アスコクロリン誘導体

Publications (2)

Publication Number Publication Date
ES515648A0 ES515648A0 (es) 1983-11-01
ES8400382A1 true ES8400382A1 (es) 1983-11-01

Family

ID=26473856

Family Applications (2)

Application Number Title Priority Date Filing Date
ES515648A Expired ES8400382A1 (es) 1981-09-10 1982-09-10 Un derivado de ascoclorina
ES522459A Granted ES522459A0 (es) 1981-09-10 1983-05-16 Un procedimiento para la preparacion de un derivado de ascoclorina.

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES522459A Granted ES522459A0 (es) 1981-09-10 1983-05-16 Un procedimiento para la preparacion de un derivado de ascoclorina.

Country Status (9)

Country Link
US (2) US4500544A (es)
EP (1) EP0074628B1 (es)
KR (1) KR880002433B1 (es)
AR (1) AR242373A1 (es)
CA (1) CA1192557A (es)
CS (1) CS244911B2 (es)
DE (1) DE3271383D1 (es)
ES (2) ES8400382A1 (es)
MX (1) MX157777A (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5409951A (en) * 1990-06-15 1995-04-25 Novo Nordisk A/S Fungicidally active compounds
US5139481A (en) * 1991-08-07 1992-08-18 The General Hospital Corporation Treatment for type II diabetes
JPH0816057B2 (ja) * 1992-09-10 1996-02-21 田村 學造 グリケイション阻害剤
US5420334A (en) * 1994-04-04 1995-05-30 Merck & Co., Inc. Inhibitors of farnesyl-protein transferase
EP0743820A4 (en) 1994-12-13 1997-06-11 Peter K Law TREATMENT OF MAMMAL-SPECIFIC CONDITIONS WITH MYOBLASTS
BR9610207A (pt) * 1995-08-28 1999-02-02 American Home Prod Acidos fenóxi acéticos como inibidores da aldose redutase e agentes anti-hiperglicêmicos
EP1142870A1 (en) 1998-12-14 2001-10-10 Nuclear Receptor Research Limited Novel ligands of nuclear receptor
CA2366281A1 (en) * 1999-03-11 2000-09-14 Nuclear Receptor Research Limited Novel ligands of nuclear receptors ppar's
US20050153870A1 (en) * 2002-01-31 2005-07-14 Kunio Ando Medicinal composition for diagnosis, prevention, or therapy of multiple risk factor syndrome
WO2013059606A1 (en) 2011-10-21 2013-04-25 Tufts Medical Center, Inc. Compounds and methods for the treatment of muscular disease, and related screening methods

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3546073A (en) * 1968-08-13 1970-12-08 American Cyanamid Co Fusarium fermentation
US3995061A (en) * 1974-04-09 1976-11-30 Chugai Seiyaku Kabushiki Kaisha Pharmaceutical composition and method of using the same

Also Published As

Publication number Publication date
ES8406995A1 (es) 1984-08-16
AR242373A1 (es) 1993-03-31
EP0074628A2 (en) 1983-03-23
DE3271383D1 (en) 1986-07-03
EP0074628B1 (en) 1986-05-28
ES515648A0 (es) 1983-11-01
ES522459A0 (es) 1984-08-16
CS652682A2 (en) 1985-09-17
US4500544A (en) 1985-02-19
KR880002433B1 (ko) 1988-11-12
EP0074628A3 (en) 1984-01-18
KR840001543A (ko) 1984-05-07
MX157777A (es) 1988-12-09
CS244911B2 (en) 1986-08-14
CA1192557A (en) 1985-08-27
US4542143A (en) 1985-09-17

Similar Documents

Publication Publication Date Title
NO972155L (no) Fremgangsmåte og opplösning for dannelse av et konversjonsbelegg på en metalloverflate
IL115105A (en) Topical ketoconazole emulsions lacking sodium sulfite
JPS5251327A (en) 3-trihydroxygermylpropionic acid and its salts and process for prepari ng the same
NO930232D0 (no) Vateritt og fremstillingsmetode
EP0037486A3 (en) Metal chelates of 1,4-bis(substituted-amino)-5,8-dihydroxy-anthraquinones
ES8603351A1 (es) Un metodo para someter a tratamiento un sistema acuoso susceptible de ser sujeto a contaminacion biologica
BA97167B1 (bs) Postupak za pripravu 7,16-dioksa-2 aza-10-0-kladinozil-12-0 desozaminil-4,5-dihidroksi-6-etil 3,5,9,11,13,15-heksametilbiciklo (11.2.1)heksadeka-1 (2)-en-8-ona
BR8100127A (pt) Composicoes a serem ingeridas pelos rminantes, processo para a sua preparacao e processo para a alimentacao dos ruminantes
IE33111B1 (en) Spiro-imidazoline-phthalan derivatives and a process for the manufacture thereof
KR900700461A (ko) 5-원자 질소 함유 이종원자 방향족 화합물의 제조방법
JPS5412921A (en) Collator
ES8301465A1 (es) Procedimiento para preparar derivados de 11- hidroxi-13 oxa-prostaglandina.
BG38640A3 (en) Method for preparing n- arylsulphenyl- n- diaryloxy- phosphinylmethylglycinates
Bowcock Present Value of£ 1
JPS53141284A (en) N u4 -dialkylaminomethylenearabinofuranosylcytosine and process for its preparation
ES2073606T3 (es) Procedimiento para la preparacion de derivados de acido beta-resorcilico.
JPS5271489A (en) Synthesis of josamycin derivative
JPS51144319A (en) Process for repairing terminal rod for electrolitic furnace of aluminu m
AT351521B (de) Verfahren zur herstellung neuer 2,6-bis- (aminoacylamino)-anthrachinone sowie ihrer saeureadditionssalze
JPS5390246A (en) 2-hydroxymethyl-3,4-di-substd-cyclopentanone derivs. and process for their preparation
JPS52100457A (en) 5-hydroxy-4-homoisotwistane and method of making same
JPS529500A (en) Plastic card forming method
JPS53103434A (en) 2,4-bis(2-chloro-4-trifluoromethoxyphenoxy)-nitrobenzene and process for their preparation
JPS5216380A (en) Identification of hen's egg whether fertilazated or not and of male or female for the fertilizated one
JPS51112711A (en) Valve sheet