ES8401007A1 - "procedimiento para preparar un acido x-arilalcanoico". - Google Patents

"procedimiento para preparar un acido x-arilalcanoico".

Info

Publication number
ES8401007A1
ES8401007A1 ES511816A ES511816A ES8401007A1 ES 8401007 A1 ES8401007 A1 ES 8401007A1 ES 511816 A ES511816 A ES 511816A ES 511816 A ES511816 A ES 511816A ES 8401007 A1 ES8401007 A1 ES 8401007A1
Authority
ES
Spain
Prior art keywords
alpha
precursors
manufacture
arylalkanoic acids
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES511816A
Other languages
English (en)
Other versions
ES511816A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Syntex Pharmaceuticals International Ltd
Original Assignee
Syntex Pharmaceuticals International Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syntex Pharmaceuticals International Ltd filed Critical Syntex Pharmaceuticals International Ltd
Publication of ES8401007A1 publication Critical patent/ES8401007A1/es
Publication of ES511816A0 publication Critical patent/ES511816A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/09—Preparation of carboxylic acids or their salts, halides or anhydrides from carboxylic acid esters or lactones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/63—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by introduction of halogen; by substitution of halogen atoms by other halogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C41/00—Preparation of ethers; Preparation of compounds having groups, groups or groups
    • C07C41/48—Preparation of compounds having groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/27—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation
    • C07C45/29—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation of hydroxy groups
    • C07C45/292—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation of hydroxy groups with chromium derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/45—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
    • C07C45/46—Friedel-Crafts reactions
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/84—Ketones containing a keto group bound to a six-membered aromatic ring containing ether groups, groups, groups, or groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/30—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Cosmetics (AREA)

Abstract

PROCEDIMIENTO PARA PREPARAR UN ACIDO A-ARILALCANOICO.SE SOMETE A TRANSPOSICION UN CETAL O UN TIOCETAL DE UN COMPUESTO (II) EN PRESENCIA DE UN DISOLVENTE PROTICO O DIPOLAR O APROTICO; SE FORMA EL ACIDO ALFA-ARILALCANOICO O UN ESTER, UN ORTOESTER O UNA AMIDA DEL MISMO. SE OBTIENE EL COMPUESTO (I), EN EL CUAL AR ES UN RESTO ARILICO Y R1 ES ALCOHILO CON 1 A 8 ATOMOS DE CARBONO O UN CICLOALCOHILO CON 3-7 ATOMOS DE CARBONO. EL MEDIO DISOLVENTE, CONTIENE UNA SAL QUE NO INTERFIERE DE UN ANION CARBONATO, BICARBONATO O FOSFATO, O UN ANION DE UN SEGUNDO ACIDO ORGANICO.
ES511816A 1981-04-30 1982-04-29 "procedimiento para preparar un acido x-arilalcanoico". Granted ES511816A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US25911981A 1981-04-30 1981-04-30

Publications (2)

Publication Number Publication Date
ES8401007A1 true ES8401007A1 (es) 1983-12-01
ES511816A0 ES511816A0 (es) 1983-12-01

Family

ID=22983610

Family Applications (2)

Application Number Title Priority Date Filing Date
ES511816A Granted ES511816A0 (es) 1981-04-30 1982-04-29 "procedimiento para preparar un acido x-arilalcanoico".
ES524528A Expired ES8601839A1 (es) 1981-04-30 1983-07-28 Procedimiento para preparar un acido alfa-arilalcanoico.

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES524528A Expired ES8601839A1 (es) 1981-04-30 1983-07-28 Procedimiento para preparar un acido alfa-arilalcanoico.

Country Status (21)

Country Link
EP (1) EP0064394A1 (es)
JP (1) JPS57192325A (es)
KR (1) KR890002772B1 (es)
AU (1) AU8313382A (es)
CA (1) CA1199646A (es)
CS (1) CS241104B2 (es)
DD (1) DD202688A5 (es)
DK (1) DK192982A (es)
ES (2) ES511816A0 (es)
FI (1) FI821501A7 (es)
GR (1) GR75425B (es)
HU (1) HU189577B (es)
IL (1) IL65629A (es)
IN (1) IN155753B (es)
NO (3) NO821417L (es)
NZ (1) NZ200458A (es)
PH (1) PH24244A (es)
PL (1) PL139818B1 (es)
PT (1) PT74818B (es)
RO (1) RO83840B1 (es)
ZA (1) ZA822955B (es)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ198271A (en) * 1980-09-11 1985-05-31 Syntex Pharma Int Preparation of alpha-aromatic-substituted alkanoic acids and intermediates
FI82680C (fi) * 1981-12-11 1991-04-10 Syntex Pharma Int Framstaellning av - arylalkansyror.
ATE23987T1 (de) * 1984-02-02 1986-12-15 Zambon Spa Verfahren zur herstellung von alpharylalkans|uren.
IT1173216B (it) * 1984-02-03 1987-06-18 Zambon Spa Processo per la preparazione di acidi alfa-idrossiaril-alcanoici
IT1196013B (it) * 1984-02-03 1988-11-10 Zambon Spa Procedimento per preparare acidi alfa-aril-alcanoici
EP0160241B1 (en) * 1984-04-14 1988-11-30 Kyowa Hakko Kogyo Co., Ltd. Process for producing an alpha-aromatic group substituted alkanoic acid derivative
US4608441A (en) * 1984-07-11 1986-08-26 Blaschim S.P.A. Process for the preparation of arylalkanoic acids by oxidative rearrangement of arylalkanones
IT1201443B (it) * 1985-07-31 1989-02-02 Zambon Spa Intermedi per la sintesi di acidi carbossilici
JPS62263153A (ja) * 1986-05-28 1987-11-16 エフ・ホフマン―ラ　ロシユ　アーゲー カルバゾ−ル誘導体
IT1197800B (it) * 1986-08-01 1988-12-06 Zambon Spa Processo per la sintesi di acidi carbossilici
US4761497A (en) * 1987-10-13 1988-08-02 Eastman Kodak Company Process for preparing 2-naphthanoic acids and esters thereof
IT1251958B (it) * 1991-10-18 1995-05-27 Zambon Spa Processo per la dealogenazione di derivati del naftalene
JP3744060B2 (ja) * 1996-06-20 2006-02-08 ダイソー株式会社 アシルオキシスルホン酸エステル誘導体の製造法
ES2797777T3 (es) 2017-04-24 2020-12-03 Igm Group B V Funcionalización oxidante simple de alquil aril cetonas
CN114644554A (zh) * 2020-12-21 2022-06-21 上海医药工业研究院 (s)-氟比洛芬的制备方法及其中间体

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE50897B1 (en) * 1980-02-26 1986-08-06 Blaschim Spa Process for preparing esters of alkanoic acids via rearrangement of alpha-haloketals
JPS5798232A (en) * 1980-11-10 1982-06-18 Sagami Chem Res Center 1-(6-methoxy-2-naphthyl)-2-oxy-1-alkanone acetal
NZ198271A (en) * 1980-09-11 1985-05-31 Syntex Pharma Int Preparation of alpha-aromatic-substituted alkanoic acids and intermediates
JPS57144234A (en) * 1981-03-03 1982-09-06 Sagami Chem Res Center 1-halophenyl-2-oxy-1-alkanone acetal

Also Published As

Publication number Publication date
RO83840B1 (ro) 1984-04-30
PT74818A (en) 1982-05-01
KR830010036A (ko) 1983-12-24
AU8313382A (en) 1982-11-04
CS310082A2 (en) 1985-07-16
CA1199646A (en) 1986-01-21
IL65629A (en) 1987-08-31
EP0064394A1 (en) 1982-11-10
GR75425B (es) 1984-07-17
ES511816A0 (es) 1983-12-01
NO824255L (no) 1982-11-01
CS241104B2 (en) 1986-03-13
PL139818B1 (en) 1987-02-28
RO83840A2 (ro) 1984-04-02
ZA822955B (en) 1983-12-28
IN155753B (es) 1985-03-02
DK192982A (da) 1982-10-31
HU189577B (en) 1986-07-28
FI821501A0 (fi) 1982-04-29
NZ200458A (en) 1985-11-08
PT74818B (en) 1983-10-28
FI821501A7 (fi) 1982-10-31
ES524528A0 (es) 1985-12-01
JPS57192325A (en) 1982-11-26
NO821417L (no) 1982-11-01
KR890002772B1 (ko) 1989-07-28
NO831338L (no) 1982-11-01
PH24244A (en) 1990-05-04
IL65629A0 (en) 1982-07-30
DD202688A5 (de) 1983-09-28
ES8601839A1 (es) 1985-12-01
PL236221A1 (es) 1982-12-06

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19970303