ES8401942A1 - Procedimiento para la preparacion de n-piridil-amidas de acido 1-fenil-ciclopentancarboxilico. - Google Patents

Procedimiento para la preparacion de n-piridil-amidas de acido 1-fenil-ciclopentancarboxilico.

Info

Publication number
ES8401942A1
ES8401942A1 ES518137A ES518137A ES8401942A1 ES 8401942 A1 ES8401942 A1 ES 8401942A1 ES 518137 A ES518137 A ES 518137A ES 518137 A ES518137 A ES 518137A ES 8401942 A1 ES8401942 A1 ES 8401942A1
Authority
ES
Spain
Prior art keywords
antiinflammatory
preparation
pharmaceutical compositions
new compounds
antitussive activity
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES518137A
Other languages
English (en)
Other versions
ES518137A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Medea Research SRL
Original Assignee
Medea Research SRL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from IT8125570A external-priority patent/IT1226048B/it
Priority claimed from IT24116/82A external-priority patent/IT1154522B/it
Application filed by Medea Research SRL filed Critical Medea Research SRL
Publication of ES518137A0 publication Critical patent/ES518137A0/es
Publication of ES8401942A1 publication Critical patent/ES8401942A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/75—Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pyridine Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

PROCEDIMIENTO PARA LA PREPARACION DE N-PIRIDIL-AMIDAS DE ACIDO 1-FENIL-CICLOPENTACARBOXILICO, DE FORMULA (I), EN LA QUE PY ES EL ANILLO DE PIRIDINA, EVENTUALMENTE SUSTITUIDO POR UNO O MAS GRUPOS DE METILO O ATOMOS DE CLORO.CONSISTE EN HACER REACCIONAR DERIVADOS ACTIVADOS DE ACIDO 1-FENIL-CICLOPENTAN-CARBOXIL ICO, DE FORMULA GENERAL (II), CON AMINOPIRIDINAS, DE FORMULA (III), EN LAS QUE X ES UN ATOMO DE HALOGENO O UN GRUPO ALCOXILO: Y R Y RK, IGUALES O DIFERENTES, REPRESENTAN ATOMOS DE HIDROGENO, GRUPOS METILO O ATOMOS DE CLORO.DE APLICACION EN COMPOSICIONES FARMACEUTICAS POR SU ACTIVIDAD ANTIINFLAMATORIA.
ES518137A 1981-12-14 1982-12-13 Procedimiento para la preparacion de n-piridil-amidas de acido 1-fenil-ciclopentancarboxilico. Expired ES8401942A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT8125570A IT1226048B (it) 1981-12-14 1981-12-14 Composti ad attivita'antiinfiammatoria, processo per la loro preparazione e composizioni farmaceutiche relative
IT24116/82A IT1154522B (it) 1982-11-08 1982-11-08 Composti ad attivita' antiinfirmmatoria, processo per la loro preparazione e composizioni farmaceutiche relative

Publications (2)

Publication Number Publication Date
ES518137A0 ES518137A0 (es) 1984-01-16
ES8401942A1 true ES8401942A1 (es) 1984-01-16

Family

ID=26328463

Family Applications (1)

Application Number Title Priority Date Filing Date
ES518137A Expired ES8401942A1 (es) 1981-12-14 1982-12-13 Procedimiento para la preparacion de n-piridil-amidas de acido 1-fenil-ciclopentancarboxilico.

Country Status (3)

Country Link
EP (1) EP0081756B1 (es)
DE (1) DE3263567D1 (es)
ES (1) ES8401942A1 (es)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT2404919E (pt) 2005-11-08 2013-10-22 Vertex Pharma Composto heterocíclico útil como um modulador de transportadores de cassete de ligação a atp
US7671221B2 (en) 2005-12-28 2010-03-02 Vertex Pharmaceuticals Incorporated Modulators of ATP-Binding Cassette transporters
US7754739B2 (en) 2007-05-09 2010-07-13 Vertex Pharmaceuticals Incorporated Modulators of CFTR
EP2164840A2 (en) 2007-05-09 2010-03-24 Vertex Pharmaceuticals Incorporated Modulators of cftr
CA2989620C (en) 2007-12-07 2022-05-03 Vertex Pharmaceuticals Incorporated Processes for producing cycloalkylcarboxamido-pyridine benzoic acids
HUE049642T2 (hu) 2007-12-07 2020-09-28 Vertex Pharma 3-(6-(1-(2,2-Difluorbenzo[d][1,3]dioxol-5-il)-ciklopropánkarboxamido)-3-metilpiridin-2-il)-benzoesav szilárd formái
CA2716109C (en) 2008-02-28 2016-07-19 Vertex Pharmaceuticals Incorporated Heteroaryl derivatives as cftr modulators
NZ616097A (en) * 2008-03-31 2015-04-24 Vertex Pharma Pyridyl derivatives as cftr modulators
AU2013270464B2 (en) * 2008-03-31 2016-05-26 Vertex Pharmaceuticals Incorporated Pyridyl derivatives as CFTR modulators
ES2900353T3 (es) 2010-04-07 2022-03-16 Vertex Pharma Composiciones farmacéuticas de ácido 3-(6-(1-(2,2-difluorobenzo[d][1,3]dioxol-5-il)ciclopropanocarboxamido)-3-metilpiriidin-2-il)benzoico y administración de las mismas
NZ727015A (en) 2012-01-25 2017-12-22 Vertex Pharma Formulations of 3-(6-(1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl) cyclopropanecarboxamido)-3-methylpyridin-2-yl)benzoic acid
CA2930199C (en) 2013-11-12 2022-10-25 Vertex Pharmaceuticals Incorporated Process of preparing pharmaceutical compositions for the treatment of cftr mediated diseases
EP2878339A1 (en) 2013-12-02 2015-06-03 Siena Biotech S.p.A. SIP3 antagonists
HUE055423T2 (hu) 2014-11-18 2021-11-29 Vertex Pharma Eljárás nagy áteresztõképességû tesztelõ nagy teljesítményû folyadék-kromatográfia elvégzésére

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1584802A (es) * 1968-09-09 1970-01-02

Also Published As

Publication number Publication date
EP0081756B1 (en) 1985-05-15
ES518137A0 (es) 1984-01-16
EP0081756A1 (en) 1983-06-22
DE3263567D1 (en) 1985-06-20

Similar Documents

Publication Publication Date Title
AU589427B2 (en) Pyridonecarboxylic acid derivatives and process for their preparation
GB1268243A (en) 0,2,4,5,-tetrahydro-3h,3-benzazepines
ES8800272A1 (es) Un procedimiento para la preparacion de polipeptidos.
EP0104522A3 (en) New pyrazolo(3,4-b)pyridine derivatives and process for producing them
HUT37411A (en) Process for the production of 1,5-benzothiazapine-derivatives
ES8606282A1 (es) Un procedimiento de preparar derivados de acidos quinolin- ynaftiridin-carboxilicos
GB1430720A (en) Furo 2,3alpha pyrimidines their process of preparation and their therapeutic application
HUT46895A (en) Process for production of new 5-lipoxigenase bicyclic compounds with inhibiation effect
JPS5576872A (en) Imidazolidinone derivative
ES472295A1 (es) Procedimiento de obtencion de nuevas acilureas con actividadfarmacologica
JPS5564592A (en) Thiazolo 3, 2-a pyrimidine derivative, its preparation, and drug comprising it
AU635463B2 (en) 2-amino-t trahydro-isoquinoline derivatives and a process for the preparation thereof and pharmaceutical compositions containing same
ES481418A1 (es) Un procedimiento para preparar un compuesto de 5,8-dihidro- furo 3,2-b, 1,8-naftiridina
JPS5772981A (en) 1,8-naphthyridine derivative and its salt
ES8404358A1 (es) Un procedimiento para obtener derivados de isoxazolopirimidina.
ES8300747A1 (es) Procedimiento para la preparacion de derivados de acido in- dolacetico
JPS5564591A (en) Thiazolo 3, 2-a pyrimidine derivative, its preparation, and drug comprising it
DE3263316D1 (en) New compound having analgesic, antiinflammatory and mucoregulating activities, process for its production and relative pharmaceutical compositions
JPS5549386A (en) Heterocyclic compound and its acid addition salt
JPS57149289A (en) Thiazinobenzoazepin derivative
FI104078B1 (fi) Menetelmä terapeuttisesti käyttökelpoisten (3-(1-piperatsinyyli)tieno[2,3-b]- ja -[2,3-c]pyridiinijohdannaisten valmistamiseksi
JPS57197258A (en) Sulfonic ester derivative and its preparation
JPS55104266A (en) Novel pyridone derivative
ES8304137A1 (es) Un procedimiento para la preparacion de compuestos b -lactamicos.
DE3469734D1 (en) Biphenylylalkanoic acid derivatives, methods of preparation and pharmaceutical compositions therefrom

Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20001009