ES8401972A1 - "un procedimiento para la preparacion de un nuevo compuesto biciclico". - Google Patents

"un procedimiento para la preparacion de un nuevo compuesto biciclico".

Info

Publication number
ES8401972A1
ES8401972A1 ES514126A ES514126A ES8401972A1 ES 8401972 A1 ES8401972 A1 ES 8401972A1 ES 514126 A ES514126 A ES 514126A ES 514126 A ES514126 A ES 514126A ES 8401972 A1 ES8401972 A1 ES 8401972A1
Authority
ES
Spain
Prior art keywords
formula
compound
group
procedure
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES514126A
Other languages
English (en)
Other versions
ES514126A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Richter Gedeon Vegyeszeti Gyar Nyrt
Original Assignee
Richter Gedeon Vegyeszeti Gyar RT
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszeti Gyar RT filed Critical Richter Gedeon Vegyeszeti Gyar RT
Publication of ES8401972A1 publication Critical patent/ES8401972A1/es
Publication of ES514126A0 publication Critical patent/ES514126A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

PROCEDIMIENTO PARA LA PREPARACION DE COMPUESTOS BICICLICOS.CONSISTE EN: A) LA REACCION DE UN COMPUESTO DE FORMULA (II) O EL ALCOHOLATO DE METAL ALCALINO EN 9 CON UN COMPUESTO DE FORMULA (III) PARA OBTENER COMPUESTOS DE FORMULA (I), DONDE R ES UN GRUPO HIDROXI ETERIFICADO DE LA FORMULA -OR; O B) LA REACCION DE UN COMPUESTO DE FORMULA (II) CON UN ACIDO CARBOXILICO DE FORMULA (IV), EN PRESENCIA DE UN AGENTE DE FIJACION DE ACIDO O DE UN METAL ALCALINO, PARA OBTENER COMPUESTOS DE FORMULA (I), DONDE R ES UN GRUPO HIDROXI ESTERIFICADO DE LA FORMULA -O-CO-R. LOSRADICALES R Y R REPRESENTAN UN GRUPO ALCOHILO DE C 1 A 6, R ES UN GRUPO BENCILO, DIFENILMETILO O FENILO, Y EL GRUPO -OCO-R ES UN GRUPO FENIL -(C1-5-ALCOHIL)-CARBONILOXI, CINAMOILOXI, BENZOILOXI, BENCILOILOXI, XANTENO-9-CARBONILOXI Y OTROS.DE APLICACION FARMACOLOGICA EN LA TERAPIA DE LOS TRASTORNOS DEL RITMO CARDIACO.
ES514126A 1981-07-20 1982-07-19 "un procedimiento para la preparacion de un nuevo compuesto biciclico". Granted ES514126A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU812112A HU184960B (en) 1981-07-20 1981-07-20 Process for preparing new derivatives of 3,7-diazabicyclo/3.3.1/ nonane

Publications (2)

Publication Number Publication Date
ES8401972A1 true ES8401972A1 (es) 1984-01-01
ES514126A0 ES514126A0 (es) 1984-01-01

Family

ID=10957812

Family Applications (2)

Application Number Title Priority Date Filing Date
ES514126A Granted ES514126A0 (es) 1981-07-20 1982-07-19 "un procedimiento para la preparacion de un nuevo compuesto biciclico".
ES520567A Expired ES8404354A1 (es) 1981-07-20 1983-03-14 Un procedimiento para la preparacion de un nuevo compuesto biciclico.

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES520567A Expired ES8404354A1 (es) 1981-07-20 1983-03-14 Un procedimiento para la preparacion de un nuevo compuesto biciclico.

Country Status (31)

Country Link
US (1) US4451473A (es)
JP (1) JPS5849383A (es)
AR (1) AR230447A1 (es)
AT (1) AT379809B (es)
AU (1) AU552770B2 (es)
BE (1) BE893891A (es)
CA (1) CA1254208A (es)
CH (1) CH653032A5 (es)
CS (1) CS235302B2 (es)
DD (1) DD202575A5 (es)
DE (1) DE3226921C2 (es)
DK (1) DK160875C (es)
ES (2) ES514126A0 (es)
FI (1) FI71320C (es)
FR (1) FR2510575B1 (es)
GB (1) GB2102801B (es)
GR (1) GR76874B (es)
HU (1) HU184960B (es)
IL (1) IL66277A (es)
IN (1) IN155994B (es)
IT (1) IT1190920B (es)
MX (1) MX159288A (es)
NL (1) NL8202908A (es)
NO (1) NO157421C (es)
PH (1) PH18502A (es)
PL (2) PL135814B1 (es)
PT (1) PT75265B (es)
SE (1) SE450704B (es)
SU (2) SU1222197A3 (es)
YU (1) YU45867B (es)
ZA (1) ZA824809B (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5036153A (en) * 1989-05-11 1991-07-30 Braish Tamim F Preparation of 2,5-diazabicyclo[2.2.1]heptanes and intermediates
NZ274915A (en) * 1993-12-29 1997-11-24 Pfizer N-(hetero)aryl methyl diazabicycloalkane derivatives
GB9726630D0 (en) 1997-12-18 1998-02-18 Glaxo Group Ltd Kv2.1 Antagonists
WO2001044243A2 (en) * 1999-12-14 2001-06-21 Neurosearch A/S Novel heteroaryl-diazabicycloalkanes
JP4804346B2 (ja) 2004-03-31 2011-11-02 日本曹達株式会社 環状アミン化合物および有害生物防除剤
UA86328C2 (uk) * 2005-10-06 2009-04-10 Ниппон Сода Ко., Лтд. Циклічні амінові сполуки, засіб для боротьби зі шкідниками
NZ567127A (en) * 2005-10-06 2010-04-30 Nippon Soda Co Bridged cyclic amine compound and pest control agent
SI2152670T1 (sl) * 2007-04-27 2014-04-30 Actelion Pharmaceuticals Ltd. Premoščene šestčlenske obročne spojine
WO2020163689A1 (en) 2019-02-08 2020-08-13 University Of Pittsburgh - Of The Commonwealth System Of Higher Education 20-hete formation inhibitors

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3078272A (en) * 1963-02-19 N-aza-bicyclo-alkylene-imino
DE2428792A1 (de) * 1974-06-14 1976-01-02 Knoll Ag Neue antiarrhythmika
DE2726571A1 (de) * 1977-06-13 1978-12-21 Basf Ag Neue bispidinderivate, verfahren zu deren herstellung und arzneimittel, welche diese enthalten

Also Published As

Publication number Publication date
AT379809B (de) 1986-03-10
JPH0352465B2 (es) 1991-08-12
HU184960B (en) 1984-11-28
DE3226921A1 (de) 1983-02-10
SU1222197A3 (ru) 1986-03-30
IT1190920B (it) 1988-02-24
FI71320C (fi) 1986-12-19
DE3226921C2 (de) 1994-03-10
IT8222448A0 (it) 1982-07-19
SE8204393D0 (sv) 1982-07-19
PH18502A (en) 1985-08-02
DK319982A (da) 1983-01-21
CH653032A5 (de) 1985-12-13
FI822526A0 (fi) 1982-07-15
ATA272382A (de) 1985-07-15
PL135878B1 (en) 1985-12-31
YU157182A (en) 1986-10-31
SE450704B (sv) 1987-07-20
CS235302B2 (en) 1985-05-15
NO157421B (no) 1987-12-07
NO157421C (no) 1988-03-16
SU1272990A3 (ru) 1986-11-23
IN155994B (es) 1985-04-20
GR76874B (es) 1984-09-04
IL66277A0 (en) 1982-11-30
YU45867B (sh) 1992-09-07
US4451473A (en) 1984-05-29
ES520567A0 (es) 1984-05-01
NO822485L (no) 1983-01-21
AR230447A1 (es) 1984-04-30
SE8204393L (sv) 1983-01-21
CA1254208A (en) 1989-05-16
JPS5849383A (ja) 1983-03-23
FI71320B (fi) 1986-09-09
DD202575A5 (de) 1983-09-21
AU552770B2 (en) 1986-06-19
ES514126A0 (es) 1984-01-01
FR2510575B1 (fr) 1986-02-07
AU8617682A (en) 1983-01-27
PL135814B1 (en) 1985-12-31
NL8202908A (nl) 1983-02-16
PL237566A1 (en) 1984-03-12
FR2510575A1 (fr) 1983-02-04
GB2102801B (en) 1985-03-27
DK160875B (da) 1991-04-29
PT75265B (en) 1984-07-02
ES8404354A1 (es) 1984-05-01
IL66277A (en) 1985-08-30
MX159288A (es) 1989-05-12
IT8222448A1 (it) 1984-01-19
PT75265A (en) 1982-08-01
PL244329A1 (en) 1984-05-07
GB2102801A (en) 1983-02-09
DK160875C (da) 1991-10-14
BE893891A (fr) 1983-01-20
FI822526L (fi) 1983-01-21
ZA824809B (en) 1983-04-27

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19981103