ES8502428A1 - Procedimiento para preparar nuevas semicarbazidas - Google Patents
Procedimiento para preparar nuevas semicarbazidasInfo
- Publication number
- ES8502428A1 ES8502428A1 ES532180A ES532180A ES8502428A1 ES 8502428 A1 ES8502428 A1 ES 8502428A1 ES 532180 A ES532180 A ES 532180A ES 532180 A ES532180 A ES 532180A ES 8502428 A1 ES8502428 A1 ES 8502428A1
- Authority
- ES
- Spain
- Prior art keywords
- carbon atoms
- alkyl
- semicarbazids
- procedure
- phenyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 125000004432 carbon atom Chemical group C* 0.000 abstract 7
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 229910052739 hydrogen Inorganic materials 0.000 abstract 3
- 239000001257 hydrogen Substances 0.000 abstract 3
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000001624 naphthyl group Chemical group 0.000 abstract 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- -1 carbonyl-methyl Chemical group 0.000 abstract 1
- 239000000496 cardiotonic agent Substances 0.000 abstract 1
- 230000003177 cardiotonic effect Effects 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 231100000252 nontoxic Toxicity 0.000 abstract 1
- 230000003000 nontoxic effect Effects 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
- C07D239/94—Nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pyrrole Compounds (AREA)
- Compositions Of Macromolecular Compounds (AREA)
- Steroid Compounds (AREA)
- Paints Or Removers (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
- Luminescent Compositions (AREA)
- Photoreceptors In Electrophotography (AREA)
- Thiazole And Isothizaole Compounds (AREA)
Abstract
PROCEDIMIENTO PARA PREPARAR NUEVAS SEMICARBAZIDAS.CONSISTE EN HACER REACCIONAR UN COMPUESTO DE FORMULA (II) CON UNA AMINA PRIMARIA O SECUNDARIA DE FORMULA (III) PARA OBTENER NUEVAS SEMICARBAZIDAS DE FORMULA (I), DONDE R1 ES H, ALCOHILO C 1 A 4 O TRIFLUOROMETILO; R2, R3 Y R4 SON H, METILO O ETILO; R5 ES H, ALCOHILO C 1 A 8, CICLOALCOHILO C 3 A 7 Y OTROS; Y R6 ES ALCOHILO C 1 A 4. LA REACCION SE LLEVA A CABO EN PRESENCIA DE UN DISOLVENTE COMO ACETONA, DIMETILFORMAMIDA O ALCOHOLES A TEMPERATURA ENTRE 110 Y 80JC.TIENEN APLICACION COMO MEDICAMENTOS POR SER INHIBIDORES DE FOSFORO DIESTERASA Y ESTIMULANTES CARDIACOS CON LARGA DURACION DE EFECTO.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19823240456 DE3240456A1 (de) | 1982-11-02 | 1982-11-02 | Neue semicarbazide, ihre herstellung und verwendung |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES8502428A1 true ES8502428A1 (es) | 1985-01-01 |
| ES532180A0 ES532180A0 (es) | 1985-01-01 |
Family
ID=6177119
Family Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES526919A Granted ES526919A0 (es) | 1982-11-02 | 1983-10-31 | Procedimiento para preparar nuevas semicarbazidas |
| ES532179A Expired ES8502427A1 (es) | 1982-11-02 | 1984-05-04 | Procedimiento para preparar nuevas semicarbazidas |
| ES532178A Granted ES532178A0 (es) | 1982-11-02 | 1984-05-04 | Procedimiento para preparar nuevas semicarbazidas |
| ES532180A Granted ES532180A0 (es) | 1982-11-02 | 1984-05-04 | Procedimiento para preparar nuevas semicarbazidas |
| ES532177A Granted ES532177A0 (es) | 1982-11-02 | 1984-05-04 | Procedimiento para preparar nuevas semicarbazidas |
Family Applications Before (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES526919A Granted ES526919A0 (es) | 1982-11-02 | 1983-10-31 | Procedimiento para preparar nuevas semicarbazidas |
| ES532179A Expired ES8502427A1 (es) | 1982-11-02 | 1984-05-04 | Procedimiento para preparar nuevas semicarbazidas |
| ES532178A Granted ES532178A0 (es) | 1982-11-02 | 1984-05-04 | Procedimiento para preparar nuevas semicarbazidas |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES532177A Granted ES532177A0 (es) | 1982-11-02 | 1984-05-04 | Procedimiento para preparar nuevas semicarbazidas |
Country Status (27)
| Country | Link |
|---|---|
| US (1) | US4546102A (es) |
| EP (1) | EP0108981B1 (es) |
| JP (1) | JPH0625165B2 (es) |
| KR (1) | KR910003117B1 (es) |
| AT (1) | ATE18042T1 (es) |
| AU (1) | AU561149B2 (es) |
| CA (1) | CA1210001A (es) |
| CS (1) | CS235987B2 (es) |
| DD (1) | DD212512A5 (es) |
| DE (2) | DE3240456A1 (es) |
| DK (1) | DK157863C (es) |
| ES (5) | ES526919A0 (es) |
| FI (1) | FI77237C (es) |
| GR (1) | GR78947B (es) |
| HK (1) | HK58389A (es) |
| HU (1) | HU191889B (es) |
| IE (1) | IE56183B1 (es) |
| IL (1) | IL70103A (es) |
| NO (1) | NO167201C (es) |
| NZ (1) | NZ206120A (es) |
| PH (1) | PH20225A (es) |
| PL (1) | PL141232B1 (es) |
| PT (1) | PT77572B (es) |
| SG (1) | SG10889G (es) |
| SU (1) | SU1179926A3 (es) |
| YU (1) | YU216483A (es) |
| ZA (1) | ZA838139B (es) |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE792856A (fr) * | 1971-12-17 | 1973-06-15 | Sandoz Sa | Nouveaux derives de la triazolo-quinazoline, leur preparation et medicaments contenant ces |
| JPS55151570A (en) * | 1979-05-15 | 1980-11-26 | Takeda Chem Ind Ltd | Pyrimidine derivatives, their preparation and antimicrobial for agriculture |
-
1982
- 1982-11-02 DE DE19823240456 patent/DE3240456A1/de not_active Withdrawn
-
1983
- 1983-10-27 PT PT77572A patent/PT77572B/pt unknown
- 1983-10-28 AT AT83110812T patent/ATE18042T1/de not_active IP Right Cessation
- 1983-10-28 DE DE8383110812T patent/DE3362201D1/de not_active Expired
- 1983-10-28 YU YU02164/83A patent/YU216483A/xx unknown
- 1983-10-28 EP EP83110812A patent/EP0108981B1/de not_active Expired
- 1983-10-28 PL PL1983244355A patent/PL141232B1/pl unknown
- 1983-10-31 ES ES526919A patent/ES526919A0/es active Granted
- 1983-10-31 FI FI833971A patent/FI77237C/fi not_active IP Right Cessation
- 1983-10-31 US US06/546,864 patent/US4546102A/en not_active Expired - Fee Related
- 1983-11-01 SU SU833659009A patent/SU1179926A3/ru active
- 1983-11-01 DD DD83256216A patent/DD212512A5/de not_active IP Right Cessation
- 1983-11-01 HU HU833775A patent/HU191889B/hu not_active IP Right Cessation
- 1983-11-01 NZ NZ206120A patent/NZ206120A/en unknown
- 1983-11-01 KR KR1019830005191A patent/KR910003117B1/ko not_active Expired
- 1983-11-01 JP JP58205715A patent/JPH0625165B2/ja not_active Expired - Lifetime
- 1983-11-01 ZA ZA838139A patent/ZA838139B/xx unknown
- 1983-11-01 CA CA000440166A patent/CA1210001A/en not_active Expired
- 1983-11-01 NO NO833978A patent/NO167201C/no unknown
- 1983-11-01 IE IE2550/83A patent/IE56183B1/en not_active IP Right Cessation
- 1983-11-01 GR GR72840A patent/GR78947B/el unknown
- 1983-11-01 IL IL70103A patent/IL70103A/xx not_active IP Right Cessation
- 1983-11-01 DK DK501083A patent/DK157863C/da not_active IP Right Cessation
- 1983-11-02 CS CS838065A patent/CS235987B2/cs unknown
- 1983-11-02 PH PH29792A patent/PH20225A/en unknown
- 1983-11-02 AU AU20920/83A patent/AU561149B2/en not_active Ceased
-
1984
- 1984-05-04 ES ES532179A patent/ES8502427A1/es not_active Expired
- 1984-05-04 ES ES532178A patent/ES532178A0/es active Granted
- 1984-05-04 ES ES532180A patent/ES532180A0/es active Granted
- 1984-05-04 ES ES532177A patent/ES532177A0/es active Granted
-
1989
- 1989-02-15 SG SG108/89A patent/SG10889G/en unknown
- 1989-07-20 HK HK583/89A patent/HK58389A/xx unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ES8406440A1 (es) | Procedimiento para preparar derivados de 2-amino-3-acilamino-6-bencilamino-piridina | |
| ES467565A1 (es) | Procedimiento para la preparacion de nuevas 4-acilamino-fe- nil-etanol-aminas. | |
| ES8106904A1 (es) | Procedimiento para la preparacion de nuevas 2-alcoxi-fenil- imidazo(4,5-b)piridinas | |
| NO160445C (no) | Analogifremgangsmaate for fremstilling av terapeutisk aktive heterocykliske forbindelser. | |
| ES538933A0 (es) | Un procedimiento para preparar imidazo(1,2-c)pirimidinas | |
| ES8500953A1 (es) | Procedimiento para preparar derivados de tieno-tiazol | |
| CA1264753C (en) | 2-PYRIDYLCARBOXAMIDES | |
| ES454668A1 (es) | Procedimiento para la preparacion de nuevas homoftalimidas. | |
| ES8502426A1 (es) | Procedimiento para preparar nuevas semicarbazidas | |
| ES541822A0 (es) | Un procedimiento para preparar nuevas 1,2,4-tiadiazinas | |
| FI883965A0 (fi) | Kemiska foereningar. | |
| ATE18993T1 (de) | Dibenzocycloheptenyliden-verbindungen zur verwendung bei der modulation der immunreaktion. | |
| ES8103742A2 (es) | Un procedimiento de preparacion de nuevos derivados de 1,3-benzodioxina | |
| ES8604591A1 (es) | Procedimiento para preparar nuevas 11-piperazinil-5h-imidazo(2,1-c)(1,4)-benzodiazepinas | |
| ES500108A0 (es) | Procedimiento para preparar nuevas benzotiopirano (2,3-c)pi-ridinas |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 19971001 |