ES8503658A1 - Procedimiento para preparar fenoxipiridinas sulfuro-sustituidas teniendo actividad antiviral. desglose de la patente n 514.940. - Google Patents

Procedimiento para preparar fenoxipiridinas sulfuro-sustituidas teniendo actividad antiviral. desglose de la patente n 514.940.

Info

Publication number
ES8503658A1
ES8503658A1 ES523660A ES523660A ES8503658A1 ES 8503658 A1 ES8503658 A1 ES 8503658A1 ES 523660 A ES523660 A ES 523660A ES 523660 A ES523660 A ES 523660A ES 8503658 A1 ES8503658 A1 ES 8503658A1
Authority
ES
Spain
Prior art keywords
sulfur
antiviral activity
phenoxypyridines
substituted
substituted phenoxypyridines
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES523660A
Other languages
English (en)
Other versions
ES523660A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Dow Chemical Co
Original Assignee
Dow Chemical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dow Chemical Co filed Critical Dow Chemical Co
Publication of ES523660A0 publication Critical patent/ES523660A0/es
Publication of ES8503658A1 publication Critical patent/ES8503658A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/70—Sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pyridine Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

PROCEDIMIENTO PARA PREPARAR FENOXIPIRIDINAS SULFURO-SUSTITUIDAS CON ACTIVIDAD ANTIVIRAL, DE FORMULA GENERAL (I), EN LA QUE M REPRESENTA 1 O 2; R REPRESENTA UN GRUPO ALQUILO; R1 Y R2 REPRESENTAN CADA UNO DE ELLOS INDEPENDIENTEMENTE BROMO, CLORO, FLUORO O YODO; Y R3 REPRESENTA HIDROGENO, BROMO O FLUORO.CONSISTE EN HACER REACCIONAR UN COMPUESTO DE FORMULA (II) CON UN APROPIADO AGENTE OXIDANTE, TAL COMO ACIDO GLACIAL/PEROXIDO DE HIDROGENO.DE APLICACION EN FARMACIA Y MEDICINA POR SU ACTIVIDAD ANTIVIRAL.
ES523660A 1981-08-13 1983-06-28 Procedimiento para preparar fenoxipiridinas sulfuro-sustituidas teniendo actividad antiviral. desglose de la patente n 514.940. Expired ES8503658A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/292,467 US4371537A (en) 1981-08-13 1981-08-13 Sulfur-substituted phenoxypyridines having antiviral activity

Publications (2)

Publication Number Publication Date
ES523660A0 ES523660A0 (es) 1985-04-01
ES8503658A1 true ES8503658A1 (es) 1985-04-01

Family

ID=23124804

Family Applications (3)

Application Number Title Priority Date Filing Date
ES514940A Granted ES514940A0 (es) 1981-08-13 1982-08-12 Procedimiento para preparar fenoxipiridinas sulfuro-sustituidas teniendo actividad antiviral.
ES523661A Granted ES523661A0 (es) 1981-08-13 1983-06-28 Procedimiento para preparar fenoxipiridinas sulfuro-sustituidas teniendo actividad antiviral. desglose de la patente n 514.940.
ES523660A Expired ES8503658A1 (es) 1981-08-13 1983-06-28 Procedimiento para preparar fenoxipiridinas sulfuro-sustituidas teniendo actividad antiviral. desglose de la patente n 514.940.

Family Applications Before (2)

Application Number Title Priority Date Filing Date
ES514940A Granted ES514940A0 (es) 1981-08-13 1982-08-12 Procedimiento para preparar fenoxipiridinas sulfuro-sustituidas teniendo actividad antiviral.
ES523661A Granted ES523661A0 (es) 1981-08-13 1983-06-28 Procedimiento para preparar fenoxipiridinas sulfuro-sustituidas teniendo actividad antiviral. desglose de la patente n 514.940.

Country Status (18)

Country Link
US (1) US4371537A (es)
EP (1) EP0072529B1 (es)
JP (1) JPS5841868A (es)
KR (1) KR890001148B1 (es)
AT (1) ATE17719T1 (es)
AU (1) AU551683B2 (es)
CA (1) CA1180017A (es)
DE (1) DE3268816D1 (es)
DK (1) DK157297C (es)
ES (3) ES514940A0 (es)
GB (1) GB2103619B (es)
GR (1) GR76894B (es)
IE (1) IE53713B1 (es)
IL (1) IL66496A0 (es)
NO (1) NO159851C (es)
NZ (1) NZ201550A (es)
PH (1) PH19150A (es)
ZA (1) ZA825762B (es)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4616087A (en) * 1982-05-21 1986-10-07 The Dow Chemical Company 2,5-bis alkyl sulfonyl and 2,5-bis alkyl thio substituted-pyridines
CA1215067A (en) * 1982-10-18 1986-12-09 Sudarshan K. Malhotra 2-(6-phenoxy-3-nitro-2-pyridinoxy)-propionate compounds
US4588733A (en) * 1984-10-19 1986-05-13 Merrell Dow Pharmaceuticals Inc. 2-phenylpyrano[2,3-b]pyridines and their use in inhibiting viruses
NZ228003A (en) * 1988-02-29 1992-04-28 Colgate Palmolive Co Dispensing device with pump and removable container: nozzle has open and closed positions
IE913697A1 (en) * 1990-10-22 1992-04-22 Res Corp Technologies Inc Aryl and heteroaryl, compounds having anti-retrovirus¹activity
TW231258B (es) * 1992-05-27 1994-10-01 Shell Internat Res Schappej B V
ES2176251T3 (es) * 1993-07-28 2002-12-01 Aventis Pharma Ltd Compuestos utilizados como inhibidores de pde iv y del factor de necrosis tumoral(tnf).
US5945425A (en) * 1994-04-29 1999-08-31 G.D. Searle & Co. Method of using (H+ /K+)ATPase inhibitors as antiviral agents
DE19817264A1 (de) * 1998-04-18 1999-10-21 Bayer Ag Neue Dihydropyrimidine
AU2145500A (en) * 1998-11-30 2000-06-19 Ishihara Sangyo Kaisha Ltd. A meta-nitro phenol derivative and a process for producing it
US7064139B2 (en) * 2001-10-29 2006-06-20 Uniroyal Chemical Company, Inc. Method for treating retroviral infections
RU2011124149A (ru) * 2008-11-17 2012-12-27 Ф.Хоффманн-Ля Рош Аг Нафтилуксусные кислоты
RS52809B (sr) * 2008-11-17 2013-10-31 F. Hoffmann-La Roche Ag. Naftilsirćetne kiseline
US8188090B2 (en) * 2008-11-17 2012-05-29 Hoffman-La Roche Inc. Naphthylacetic acids
US8470884B2 (en) 2011-11-09 2013-06-25 Hoffmann-La Roche Inc. Alkenyl naphthylacetic acids
US9000044B2 (en) 2012-02-28 2015-04-07 Hoffmann-La Roche Inc. Substituted naphthylacetic acids

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH434868A (de) * 1964-02-10 1967-04-30 Ciba Geigy Schädlingsbekämpfungsmittel
US3528987A (en) * 1964-07-31 1970-09-15 Geigy Chem Corp N-(substituted pyridyl)rinolamides and -linolenamides
US3535328A (en) * 1967-09-01 1970-10-20 Exxon Research Engineering Co Certain substituted aminothioethoxy pyridines
US3549647A (en) * 1968-12-03 1970-12-22 Dow Chemical Co Bis- and tris-(thio-,sulfinyl- and sulfonyl)pyridines
US3732234A (en) * 1969-09-26 1973-05-08 Dow Chemical Co (thio-,sulfinyl-and sulfonyl)containing pyridine compounds
US3639413A (en) * 1969-09-26 1972-02-01 Dow Chemical Co (thio- sulfinyl- and sulfonyl) containing pyridine compounds
BE758759A (fr) * 1969-11-12 1971-05-10 Merck & Co Inc Pyridones anti-inflammatoires
US3687959A (en) * 1970-05-28 1972-08-29 Exxon Research Engineering Co Alkaryl-alkoxy, aryl-amido derivatives of pyridine
US3655897A (en) * 1971-01-25 1972-04-11 Merck & Co Inc Anti-inflammatory agents
US3719682A (en) * 1971-05-17 1973-03-06 Dow Chemical Co (thio-,sulfinyl-and sulfonyl)containing pyridine compounds
US3980659A (en) * 1972-06-22 1976-09-14 Cassella Farbwerke Mainkur Aktiengesellschaft Certain 6-amino-4-hydrocarbyl-nicotinamides
US3954782A (en) * 1972-06-22 1976-05-04 Cassella Farbwerke Mainkur Aktiengesellschaft 2,6-Hydrazino-3-pyridine carboxyamides
US3956294A (en) * 1972-06-22 1976-05-11 Cassella Farbwerke Mainkur Aktiengesellschaft Substituted pyridine compounds
US3962265A (en) * 1974-01-22 1976-06-08 The Dow Chemical Company H'-(4-((6-chloro-2-pyridinyl)oxy)phenyl)-n-methyl-n-(1-methyl-2-propynyl)urea
US4003733A (en) * 1974-01-22 1977-01-18 The Dow Chemical Company Substituted pyridinyloxy(thio)phenyl -acetamides, -ureas and urea derivatives
US3931201A (en) * 1974-01-22 1976-01-06 The Dow Chemical Company Substituted pyridinyloxy(thio)phenyl -acetamides, -ureas and urea derivatives
US4055650A (en) * 1974-04-17 1977-10-25 A. Christiaens Societe Anonyme Certain 4-phenoxy(or phenylthio)-3-n-acylated-sulfonamido-pyridines
NL7612668A (nl) * 1976-01-06 1977-07-08 Dow Chemical Co Werkwijze voor het bereiden van nieuwe organo- fosforusverbindingen.
US4132784A (en) * 1976-12-02 1979-01-02 The Dow Chemical Company (Substituted pyridyl)phenoxy phosphorus compounds and their use as insecticides
US4067983A (en) * 1976-12-17 1978-01-10 Parke, Davis & Company Pharmaceutical compositions and methods
EP0000176B1 (de) * 1977-06-29 1981-09-16 Ciba-Geigy Ag Pyridyloxy-phenoxy-alkancarbonsäurederivate, Verfahren zu deren Herstellung, und deren Verwendung als Herbizide oder als pflanzenwachstumsregulierende Mittel
US4212980A (en) * 1978-11-13 1980-07-15 Warner-Lambert Company 5-Phenoxy-2-pyridinecarbonitrile compounds and methods for their production
US4229457A (en) * 1979-09-27 1980-10-21 Warner-Lambert Company 3-(3-Substituted aryloxy)-2-yridinecarbonitriles, pharmaceutical compositions and methods for their production

Also Published As

Publication number Publication date
JPH0414107B2 (es) 1992-03-11
IE53713B1 (en) 1989-01-18
GR76894B (es) 1984-09-04
ES523660A0 (es) 1985-04-01
AU8707882A (en) 1983-05-12
NO822751L (no) 1983-02-14
EP0072529B1 (en) 1986-01-29
IL66496A0 (en) 1982-12-31
ATE17719T1 (de) 1986-02-15
DE3268816D1 (en) 1986-03-13
US4371537A (en) 1983-02-01
KR890001148B1 (ko) 1989-04-25
NO159851B (no) 1988-11-07
NO159851C (no) 1989-02-15
DK157297C (da) 1990-05-07
DK157297B (da) 1989-12-04
JPS5841868A (ja) 1983-03-11
EP0072529A1 (en) 1983-02-23
GB2103619A (en) 1983-02-23
IE821956L (en) 1983-02-13
ES8503656A1 (es) 1985-03-16
ES8308852A1 (es) 1983-10-16
GB2103619B (en) 1985-02-27
ES514940A0 (es) 1983-10-16
ZA825762B (en) 1983-06-29
DK362882A (da) 1983-02-14
PH19150A (en) 1986-01-15
CA1180017A (en) 1984-12-27
AU551683B2 (en) 1986-05-08
KR840001137A (ko) 1984-03-28
ES523661A0 (es) 1985-03-16
NZ201550A (en) 1985-07-12

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19970401