ES8605576A1 - Un procedimiento para preparar una composicion contra infecciones virales de hepatitis b - Google Patents

Un procedimiento para preparar una composicion contra infecciones virales de hepatitis b

Info

Publication number
ES8605576A1
ES8605576A1 ES535085A ES535085A ES8605576A1 ES 8605576 A1 ES8605576 A1 ES 8605576A1 ES 535085 A ES535085 A ES 535085A ES 535085 A ES535085 A ES 535085A ES 8605576 A1 ES8605576 A1 ES 8605576A1
Authority
ES
Spain
Prior art keywords
hepatitis
virus
antigenicity
polypeptide
extract
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES535085A
Other languages
English (en)
Other versions
ES535085A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Biogen NV
Original Assignee
Biogen NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biogen NV filed Critical Biogen NV
Publication of ES535085A0 publication Critical patent/ES535085A0/es
Publication of ES8605576A1 publication Critical patent/ES8605576A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2730/00—Reverse transcribing DNA viruses
    • C12N2730/00011—Details
    • C12N2730/10011—Hepadnaviridae
    • C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
    • C12N2730/10122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Virology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

PROCEDIMIENTO PARA PREPARAR PRODUCTOS QUE PRESENTAN LA ANTIGENICIDAD DE LOS ANTIGENOS VIRALES DE LA HEPATITIS B. COMPRENDE UNA DE LAS SECUENCIAS SIGUIENTES DE OPERACIONES: A) PREPARAR UN EXTRACTO BACTERIANO DE UN ORGANISMO HOSPEDANTE CARACTERIZADO POR LA EXPRESION DE UN POLIPEPTIDO QUE PRESENTA LA ANTIGENICIDAD DEL ANTIGENO DE NUCLEO DEL VIRUS DE LA HEPATITIS B Y TRATAR EL EXTRACTO ENZIMATICA, PROTEOLITICA O DISOCIATIVAMENTE PARA CONVERTIR UNA PARTE DEL POLIPEPTIDO EN UN POLIPEPTIDO QUE PRESENTA LA ANTIGENICIDAD DEL ANTIGENO DEL VIRUS DE LA HEPATITIS B; B) PREPARAR UN EXTRACTO BACTERIANO D EUN ORGANISMO HOSPEDANTE Y RECOGER DEL EXTRACTO UNA FRACCION QUE CONTIENE EL POLIPEPTIDO QUE PRESENTA LA ANTIGENICIDAD DEL ANTIGENO DEL VIRUS DE LA HEPATITIS B; Y C) TRATAR EL EXTACTO ENZIMATICA-PROTEOLITICA O DISOCIATIVAMENTE PARA CONVERTIR UNA PORCION DEL PRECURSOR EN UN POLIPEPTIDO QUE PRESENTA LA ANTIGENICIDAD DEL ANTIGENO E DEL VIRUS DE LA HEPATITIS B Y QUE PRODUCE EN UN PACIENTE TRATADO LA FORMACIONDE ANTICUERPOS PARA LOS ANTIGENOS E DEL VIRUS DE LA HEPATITIS B.
ES535085A 1983-08-12 1984-08-10 Un procedimiento para preparar una composicion contra infecciones virales de hepatitis b Expired ES8605576A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB838321789A GB8321789D0 (en) 1983-08-12 1983-08-12 Vaccines and compositions against hepatitis

Publications (2)

Publication Number Publication Date
ES535085A0 ES535085A0 (es) 1986-03-16
ES8605576A1 true ES8605576A1 (es) 1986-03-16

Family

ID=10547233

Family Applications (1)

Application Number Title Priority Date Filing Date
ES535085A Expired ES8605576A1 (es) 1983-08-12 1984-08-10 Un procedimiento para preparar una composicion contra infecciones virales de hepatitis b

Country Status (12)

Country Link
EP (1) EP0133599A3 (es)
JP (1) JPS6069030A (es)
KR (1) KR850001532A (es)
AU (1) AU572178B2 (es)
CA (1) CA1259566A (es)
ES (1) ES8605576A1 (es)
FI (1) FI843163A7 (es)
GB (1) GB8321789D0 (es)
HU (1) HUT34890A (es)
IL (1) IL72655A0 (es)
IN (1) IN158222B (es)
PT (1) PT79064B (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7115836B2 (ja) * 2017-11-07 2022-08-09 エム・ブイ・イー・バイオロジカル・ソリューションズ・ユー・エス・リミテッド・ライアビリティ・カンパニー 極低温冷凍機

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3636191A (en) * 1969-10-08 1972-01-18 Cancer Res Inst Vaccine against viral hepatitis and process
US4164565A (en) * 1975-03-14 1979-08-14 New York Blood Center, Inc. Vaccine for active immunization containing hepatitis B surface antigen and associated antigen
FR2303562A1 (fr) * 1975-03-14 1976-10-08 Community Blood Council Greate Nouvelle preparation d'antigene utilisable comme vaccin
US4017360A (en) * 1975-05-14 1977-04-12 Merck & Co., Inc. Method for purifying hepatitis B antigen
ZA792485B (en) * 1978-06-07 1980-06-25 New York Blood Center Inc Vaccine for active immunization containing hepatitis b surface and/or e-antigens
DK171727B1 (da) * 1978-12-22 1997-04-14 Biogen Inc Rekombinante hepatitis B virus DNA-molekyler, værtsorganismer transformeret hermed, HBV-antigenspecifikke polypeptider, DNA-sekvenser kodende for HBV-antigenspecifikke polypeptider, metoder til påvisning af hepatitis B virus-antistoffer, metoder til fremstilling af nævnte DNA-molekyler, fremgangsmåder til fremstilling af nævnte polypeptider og midler til påvisning af HBV-infektion
US4301250A (en) * 1979-11-02 1981-11-17 Merck & Co., Inc. Method of producing hepatitis B surface antigen
AU8746582A (en) * 1981-09-02 1983-03-10 Biogen N.V. Hepatitis b virus e type antigen

Also Published As

Publication number Publication date
CA1259566A (en) 1989-09-19
AU3177684A (en) 1985-02-14
EP0133599A2 (en) 1985-02-27
GB8321789D0 (en) 1983-09-14
ES535085A0 (es) 1986-03-16
IL72655A0 (en) 1984-11-30
JPS6069030A (ja) 1985-04-19
AU572178B2 (en) 1988-05-05
FI843163L (fi) 1985-02-13
HUT34890A (en) 1985-05-28
PT79064B (en) 1986-12-11
FI843163A0 (fi) 1984-08-10
FI843163A7 (fi) 1985-02-13
PT79064A (en) 1984-09-01
IN158222B (es) 1986-09-27
EP0133599A3 (en) 1985-06-12
KR850001532A (ko) 1985-03-30

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