ES8802013A1 - Procedimiento para la obtencion de esteres de acido sulfonico - Google Patents

Procedimiento para la obtencion de esteres de acido sulfonico

Info

Publication number
ES8802013A1
ES8802013A1 ES557722A ES557722A ES8802013A1 ES 8802013 A1 ES8802013 A1 ES 8802013A1 ES 557722 A ES557722 A ES 557722A ES 557722 A ES557722 A ES 557722A ES 8802013 A1 ES8802013 A1 ES 8802013A1
Authority
ES
Spain
Prior art keywords
acid esters
sulphonic
unustituted
hypertensors
renting
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES557722A
Other languages
English (en)
Other versions
ES557722A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy AG filed Critical Ciba Geigy AG
Publication of ES8802013A1 publication Critical patent/ES8802013A1/es
Publication of ES557722A0 publication Critical patent/ES557722A0/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
    • C07C309/63—Esters of sulfonic acids
    • C07C309/72—Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/30—Preparation of optical isomers
    • C07C227/32—Preparation of optical isomers by stereospecific synthesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06139—Dipeptides with the first amino acid being heterocyclic

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Neurology (AREA)
  • Genetics & Genomics (AREA)
  • Cardiology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Catalysts (AREA)
  • Detergent Compositions (AREA)

Abstract

LOS ESTERES DE ACIDO SULFONICO (I), DONDE NO EXCLUSIVAMENTE, R1 ES C5-6 CICLOALQUILO INSUSTITUIDO, R2 Y RK SON ALQUILO C1-7 Y R UN RESTO (II) O (III) CON RADICALES SEGUN SE INDICAN; SE OBTIENEN POR ALQUILACION DE UN COMPUESTO (IV) CON OTRO (V) DONDE R3 ES FENILO. APLICABLE COMO HIPERTENSORES.
ES557722A 1985-06-13 1987-09-15 Procedimiento para la obtencion de esteres de acido sulfonico Expired ES8802013A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH250185 1985-06-13

Publications (2)

Publication Number Publication Date
ES8802013A1 true ES8802013A1 (es) 1988-03-16
ES557722A0 ES557722A0 (es) 1988-03-16

Family

ID=4235223

Family Applications (2)

Application Number Title Priority Date Filing Date
ES555954A Expired ES8801197A1 (es) 1985-06-13 1986-06-11 Procedimiento para la obtencion de esteres de acido sulfurico
ES557722A Expired ES8802013A1 (es) 1985-06-13 1987-09-15 Procedimiento para la obtencion de esteres de acido sulfonico

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES555954A Expired ES8801197A1 (es) 1985-06-13 1986-06-11 Procedimiento para la obtencion de esteres de acido sulfurico

Country Status (18)

Country Link
US (2) US4785089A (es)
EP (1) EP0206993B1 (es)
JP (2) JPS61289073A (es)
KR (1) KR940007529B1 (es)
AT (1) ATE53014T1 (es)
CA (1) CA1338089C (es)
CY (1) CY1710A (es)
DD (2) DD283611A5 (es)
DE (1) DE3671439D1 (es)
DK (2) DK170277B1 (es)
ES (2) ES8801197A1 (es)
FI (1) FI86171C (es)
HK (1) HK63293A (es)
HU (1) HU203074B (es)
IE (1) IE58477B1 (es)
IL (1) IL79077A (es)
PT (1) PT82744B (es)
SG (1) SG32393G (es)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0166354B1 (en) * 1984-06-26 1992-08-05 Merck & Co. Inc. Benzofused lactam compounds and pharmaceutical compositions containing them
US4785089A (en) * 1985-06-13 1988-11-15 Ciba-Geigy Corporation Novel sulfonic acid esters and their preparation
US5145864A (en) * 1987-09-15 1992-09-08 Alcoholism And Drug Addiction Research Foundation Reduction of voluntary alcohol consumption by treatment with angiotensin converting enzyme inhibitors
US5110813A (en) * 1987-09-15 1992-05-05 Alcoholism And Drug Addiction Research Foundation Reduction of voluntary alcohol consumption by treatment with angiotensin converting enzyme inhibitors
US5371014A (en) * 1988-02-12 1994-12-06 Daicel Chemical Industries, Ltd. Process for the production of optically active 2-hydroxy acid esters using microbes to reduce the 2-oxo precursor
EP0347374B1 (de) * 1988-06-06 1993-12-15 Ciba-Geigy Ag Verfahren zur Herstellung von Hydroxysäuren
JP3915015B2 (ja) 1995-08-22 2007-05-16 味の素株式会社 光学活性２−ヒドロキシ−４−アリール酪酸またはそのエステルの製造方法
TR200002822T2 (tr) 1998-03-31 2001-01-22 Ciba Specialty Chemicals Holding Inc. HPB esterlerinin hazırlanması için bir işlem.
AU2000239828A1 (en) * 2000-04-18 2001-10-30 Scinopharm Singapore Pte Ltd Process for preparation of 3-((1'-(alkoxycarbonyl)-3'-phenylpropyl)amino)-2-oxo-(1)- benzazepine and its derivatives
CN1585744A (zh) * 2001-03-27 2005-02-23 兰贝克赛实验室有限公司 贝那普利的制备方法
EP1291336A3 (en) * 2001-09-05 2003-10-08 Solvias AG Preparation of optically active alpha-hydroxyethers
ITMI20020934A1 (it) * 2002-05-03 2003-11-03 Danimite Dipharma S P A Processo per la sintesi di benazepril cloridrato
WO2005003134A1 (en) * 2003-07-07 2005-01-13 Hetero Drugs Limited A novel process for the preparation of cilazapril
ATE425146T1 (de) * 2005-05-12 2009-03-15 Lupin Ltd Verbessertes verfahren zur kristallisierung von benazeprilhydrochlorid
CN105061312B (zh) * 2015-07-17 2017-12-12 惠州信立泰药业有限公司 一种改进的盐酸贝那普利的制备方法及含有该盐酸贝那普利的药物组合物

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5535060A (en) * 1978-09-05 1980-03-11 Agency Of Ind Science & Technol Asymmetric hydrogenation of alpha-keto-acid ester
JPS5823861B2 (ja) * 1979-06-05 1983-05-18 工業技術院長 α−ケトエステルの不斉水素化方法
US4344949A (en) * 1980-10-03 1982-08-17 Warner-Lambert Company Substituted acyl derivatives of 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acids
US4374847A (en) * 1980-10-27 1983-02-22 Ciba-Geigy Corporation 1-Carboxyalkanoylindoline-2-carboxylic acids
EP0072352B1 (de) * 1981-08-11 1986-03-05 Ciba-Geigy Ag Benzazepin-2-one, Verfahren zu ihrer Herstellung, pharmazeutische Präparate die diese Verbindungen enthalten, sowie die Verbindungen zur therapeutischen Verwendung
US4410520A (en) * 1981-11-09 1983-10-18 Ciba-Geigy Corporation 3-Amino-[1]-benzazepin-2-one-1-alkanoic acids
EP0081320A3 (en) * 1981-12-07 1984-07-18 Beecham Group Plc Preparation of acetic acid derivatives
US4473575A (en) * 1982-07-19 1984-09-25 Ciba-Geigy Corporation 3-Amino-(1)-benzazepin-2-one-1-alkanoic acids
US4470988A (en) * 1983-02-10 1984-09-11 Ciba-Geigy Corporation Benzazocinone and benzazoninone derivatives, and their pharmaceutical use
DE3315464A1 (de) * 1983-04-28 1984-10-31 Hoechst Ag, 6230 Frankfurt Verfahren zur herstellung von n-alkylierten dipeptiden und deren estern
DE3328986A1 (de) * 1983-08-11 1985-02-21 Degussa Ag, 6000 Frankfurt Verfahren zur praktisch stereospezifischen herstellung von optisch aktiven (alpha)-aminocarbonsaeureestern
US4785089A (en) * 1985-06-13 1988-11-15 Ciba-Geigy Corporation Novel sulfonic acid esters and their preparation

Also Published As

Publication number Publication date
CY1710A (en) 1994-01-14
HU203074B (en) 1991-05-28
FI86171C (fi) 1992-07-27
DK171950B1 (da) 1997-08-25
JPH0735358B2 (ja) 1995-04-19
FI862462A7 (fi) 1986-12-14
EP0206993A1 (de) 1986-12-30
DD283611A5 (de) 1990-10-17
US4785089A (en) 1988-11-15
ATE53014T1 (de) 1990-06-15
JPH05310656A (ja) 1993-11-22
SG32393G (en) 1993-05-21
DK170277B1 (da) 1995-07-24
DE3671439D1 (de) 1990-06-28
IL79077A (en) 1994-01-25
DK276386A (da) 1986-12-14
ES557722A0 (es) 1988-03-16
JPH0567140B2 (es) 1993-09-24
DK276386D0 (da) 1986-06-12
ES8801197A1 (es) 1987-12-16
KR940007529B1 (ko) 1994-08-19
US5066801A (en) 1991-11-19
KR870000291A (ko) 1987-02-17
HK63293A (en) 1993-07-09
IE58477B1 (en) 1993-09-22
DK39695A (da) 1995-04-07
ES555954A0 (es) 1987-12-16
PT82744B (pt) 1988-12-15
FI86171B (fi) 1992-04-15
CA1338089C (en) 1996-02-27
DD266097A5 (de) 1989-03-22
IE861571L (en) 1986-11-13
FI862462A0 (fi) 1986-06-09
PT82744A (en) 1986-07-01
IL79077A0 (en) 1986-09-30
EP0206993B1 (de) 1990-05-23
JPS61289073A (ja) 1986-12-19

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Legal Events

Date Code Title Description
PC1A Transfer granted
FD1A Patent lapsed

Effective date: 20080128