ATE168377T1 - Spiro(pyran)piperidine-derivate - Google Patents

Spiro(pyran)piperidine-derivate

Info

Publication number
ATE168377T1
ATE168377T1 AT90313262T AT90313262T ATE168377T1 AT E168377 T1 ATE168377 T1 AT E168377T1 AT 90313262 T AT90313262 T AT 90313262T AT 90313262 T AT90313262 T AT 90313262T AT E168377 T1 ATE168377 T1 AT E168377T1
Authority
AT
Austria
Prior art keywords
pyran
spiro
piperidine derivatives
spirocycles
chem
Prior art date
Application number
AT90313262T
Other languages
English (en)
Inventor
John J Baldwin
David A Claremon
Jason M Elliott
Gerald S Ponticello
David C Remy
Harold G Selnick
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Application granted granted Critical
Publication of ATE168377T1 publication Critical patent/ATE168377T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10Spiro-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D221/00Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/20Spiro-condensed ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/10Spiro-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/10Spiro-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D513/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/10Spiro-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Fats And Perfumes (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Dental Preparations (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Hydrogenated Pyridines (AREA)
AT90313262T 1989-12-08 1990-12-06 Spiro(pyran)piperidine-derivate ATE168377T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US44795089A 1989-12-08 1989-12-08
US61209190A 1990-11-16 1990-11-16

Publications (1)

Publication Number Publication Date
ATE168377T1 true ATE168377T1 (de) 1998-08-15

Family

ID=27035165

Family Applications (1)

Application Number Title Priority Date Filing Date
AT90313262T ATE168377T1 (de) 1989-12-08 1990-12-06 Spiro(pyran)piperidine-derivate

Country Status (17)

Country Link
EP (1) EP0431943B1 (de)
JP (1) JPH0747576B2 (de)
KR (1) KR910011859A (de)
CN (2) CN1053613A (de)
AT (1) ATE168377T1 (de)
AU (2) AU6787390A (de)
CA (1) CA2031633A1 (de)
DE (1) DE69032480T2 (de)
ES (1) ES2118715T3 (de)
FI (1) FI906045A7 (de)
HU (1) HU908122D0 (de)
IE (1) IE904430A1 (de)
IL (1) IL96507A0 (de)
NO (1) NO905306L (de)
NZ (1) NZ236315A (de)
PT (1) PT96126A (de)
YU (1) YU231790A (de)

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Also Published As

Publication number Publication date
IL96507A0 (en) 1991-08-16
FI906045A0 (fi) 1990-12-07
EP0431943A3 (en) 1992-03-25
CA2031633A1 (en) 1991-06-09
HU908122D0 (en) 1991-06-28
NZ236315A (en) 1994-09-27
CN1110685A (zh) 1995-10-25
EP0431943A2 (de) 1991-06-12
CN1053613A (zh) 1991-08-07
ES2118715T3 (es) 1998-10-01
AU6329794A (en) 1994-07-21
DE69032480T2 (de) 1999-05-06
JPH0747576B2 (ja) 1995-05-24
EP0431943B1 (de) 1998-07-15
PT96126A (pt) 1991-09-30
NO905306L (no) 1991-06-10
IE904430A1 (en) 1991-06-19
YU231790A (sh) 1993-05-28
FI906045L (fi) 1991-06-09
JPH04217960A (ja) 1992-08-07
FI906045A7 (fi) 1991-06-09
KR910011859A (ko) 1991-08-07
AU6787390A (en) 1991-06-13
NO905306D0 (no) 1990-12-07
DE69032480D1 (de) 1998-08-20

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