FI108729B - Menetelmä ei-selektoitavissa olevien geenien ekspressoimiseksi eukaryoottisoluissa, jotka eivät ole DHFR--soluja - Google Patents

Menetelmä ei-selektoitavissa olevien geenien ekspressoimiseksi eukaryoottisoluissa, jotka eivät ole DHFR--soluja Download PDF

Info

Publication number: FI108729B
Authority: FI; Finland
Prior art keywords: cells; gene; genes; selection; selectable
Prior art date: 1988-03-02

Application number

FI890946A

Other languages

English (en)

Finnish (fi)

Swedish (sv)

Other versions

FI890946L (fi

FI890946A0 (fi

Inventor

Gerd Zettlmeissl

Klaus-Dieter Langner

Manfred Wirth

Hansjoerg Hauser

Original Assignee

Behringwerke Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1988-03-02

Filing date

1989-02-28

Publication date

2002-03-15

1989-02-28 Application filed by Behringwerke Ag filed Critical Behringwerke Ag

1989-02-28 Publication of FI890946A0 publication Critical patent/FI890946A0/fi

1989-09-03 Publication of FI890946L publication Critical patent/FI890946L/fi

2002-03-15 Application granted granted Critical

2002-03-15 Publication of FI108729B publication Critical patent/FI108729B/fi

Links

108090000623 proteins and genes Proteins 0.000 title claims 11
210000004027 cell Anatomy 0.000 title claims 2
210000003527 eukaryotic cell Anatomy 0.000 title claims 2
102100024746 Dihydrofolate reductase Human genes 0.000 title 1
108020001096 dihydrofolate reductase Proteins 0.000 title 1
239000003112 inhibitor Substances 0.000 claims 2
RXWNCPJZOCPEPQ-NVWDDTSBSA-N puromycin Chemical compound C1=CC(OC)=CC=C1C[C@H](N)C(=O)N[C@H]1[C@@H](O)[C@H](N2C3=NC=NC(=C3N=C2)N(C)C)O[C@@H]1CO RXWNCPJZOCPEPQ-NVWDDTSBSA-N 0.000 claims 2
101150074155 DHFR gene Proteins 0.000 claims 1
108010092408 Eosinophil Peroxidase Proteins 0.000 claims 1
102100028471 Eosinophil peroxidase Human genes 0.000 claims 1
108010017080 Granulocyte Colony-Stimulating Factor Proteins 0.000 claims 1
102000004269 Granulocyte Colony-Stimulating Factor Human genes 0.000 claims 1
108010017213 Granulocyte-Macrophage Colony-Stimulating Factor Proteins 0.000 claims 1
102000004457 Granulocyte-Macrophage Colony-Stimulating Factor Human genes 0.000 claims 1
108010002386 Interleukin-3 Proteins 0.000 claims 1
229930193140 Neomycin Natural products 0.000 claims 1
108010022233 Plasminogen Activator Inhibitor 1 Proteins 0.000 claims 1
102100039418 Plasminogen activator inhibitor 1 Human genes 0.000 claims 1
102100033571 Tissue-type plasminogen activator Human genes 0.000 claims 1
108050006955 Tissue-type plasminogen activator Proteins 0.000 claims 1
239000003550 marker Substances 0.000 claims 1
229960004927 neomycin Drugs 0.000 claims 1
102000004169 proteins and genes Human genes 0.000 claims 1
229950010131 puromycin Drugs 0.000 claims 1
239000013598 vector Substances 0.000 claims 1
108700026220 vif Genes Proteins 0.000 claims 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/65—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression using markers
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/745—Blood coagulation or fibrinolysis factors
- C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/81—Protease inhibitors
- C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
- C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
- C07K14/8121—Serpins
- C07K14/8128—Antithrombin III
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells

Landscapes

Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Zoology (AREA)
Wood Science & Technology (AREA)
Biomedical Technology (AREA)
Biotechnology (AREA)
General Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Biophysics (AREA)
Molecular Biology (AREA)
Biochemistry (AREA)
General Health & Medical Sciences (AREA)
Microbiology (AREA)
Plant Pathology (AREA)
Physics & Mathematics (AREA)
Gastroenterology & Hepatology (AREA)
Medicinal Chemistry (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Hematology (AREA)
Toxicology (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)

FI890946A 1988-03-02 1989-02-28 Menetelmä ei-selektoitavissa olevien geenien ekspressoimiseksi eukaryoottisoluissa, jotka eivät ole DHFR--soluja FI108729B (fi)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE3806617A DE3806617A1 (de)	1988-03-02	1988-03-02	Erzeugung hochexprimierender, rekombinanter, eukaryotischer zellen
DE3806617		1988-03-02

Publications (3)

Publication Number	Publication Date
FI890946A0 FI890946A0 (fi)	1989-02-28
FI890946L FI890946L (fi)	1989-09-03
FI108729B true FI108729B (fi)	2002-03-15

Family

ID=6348554

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FI890946A FI108729B (fi)	1988-03-02	1989-02-28	Menetelmä ei-selektoitavissa olevien geenien ekspressoimiseksi eukaryoottisoluissa, jotka eivät ole DHFR--soluja

Country Status (10)

Country	Link
EP (1)	EP0330977A3 (fr)
JP (1)	JPH0223873A (fr)
KR (1)	KR0136909B1 (fr)
AU (1)	AU617438B2 (fr)
CA (1)	CA1339207C (fr)
DE (1)	DE3806617A1 (fr)
DK (1)	DK175625B1 (fr)
FI (1)	FI108729B (fr)
PT (1)	PT89880B (fr)
YU (1)	YU44789A (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ATE352612T1 (de) *	1990-08-29	2007-02-15	Pharming Intellectual Pty Bv	Homologe rekombination in säugetier-zellen
DE4037837A1 (de) *	1990-11-28	1992-06-04	Behringwerke Ag	Zellfreie rezeptorbindungsteste, ihre herstellung und verwendung
DE4322330A1 (de)	1992-08-31	1994-03-03	Behringwerke Ag	Verwendung des IL-4-Rezeptors zur Therapie, Prophylaxe und Diagnose von allergischen, viralen, parasitären und bakteriellen Erkrankungen sowie von Pilzinfektionen
DE4228839A1 (de)	1992-08-29	1994-03-03	Behringwerke Ag	Verfahren zum Nachweis und zur Bestimmung von Mediatoren
US8765370B2 (en) *	2009-06-11	2014-07-01	Scinopharm Taiwan, Ltd	Inhibition-based high-throughput screen strategy for cell clones

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1987002708A1 (fr) *	1985-10-24	1987-05-07	Siska Diagnostics, Inc.	Sondes d'acide nucleique marquees par des composes chelates de lanthanides
EP0247145B1 (fr) *	1985-11-05	1992-02-26	Genetics Institute, Inc.	Vecteurs amplifiables par multiplication pour expression d'adn hexogene en grande quantite

1988
- 1988-03-02 DE DE3806617A patent/DE3806617A1/de not_active Withdrawn
1989
- 1989-02-21 EP EP19890103030 patent/EP0330977A3/fr not_active Withdrawn
- 1989-02-28 FI FI890946A patent/FI108729B/fi not_active IP Right Cessation
- 1989-03-01 DK DK198900992A patent/DK175625B1/da not_active IP Right Cessation
- 1989-03-01 AU AU30858/89A patent/AU617438B2/en not_active Ceased
- 1989-03-01 PT PT89880A patent/PT89880B/pt not_active IP Right Cessation
- 1989-03-01 CA CA000592435A patent/CA1339207C/fr not_active Expired - Fee Related
- 1989-03-01 YU YU00447/89A patent/YU44789A/xx unknown
- 1989-03-02 KR KR1019890002552A patent/KR0136909B1/ko not_active Expired - Fee Related
- 1989-03-02 JP JP1050931A patent/JPH0223873A/ja active Pending

Also Published As

Publication number	Publication date
AU617438B2 (en)	1991-11-28
CA1339207C (fr)	1997-08-05
FI890946L (fi)	1989-09-03
YU44789A (en)	1990-06-30
DK99289D0 (da)	1989-03-01
DK175625B1 (da)	2004-12-27
DK99289A (da)	1989-09-03
JPH0223873A (ja)	1990-01-26
KR890014733A (ko)	1989-10-25
PT89880A (pt)	1989-11-10
AU3085889A (en)	1989-09-07
DE3806617A1 (de)	1989-09-14
EP0330977A3 (fr)	1991-01-23
FI890946A0 (fi)	1989-02-28
PT89880B (pt)	1994-05-31
KR0136909B1 (ko)	1998-04-25
EP0330977A2 (fr)	1989-09-06

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Legal Events

Date	Code	Title	Description
2004-08-31	FG	Patent granted	Owner name: BEHRINGWERKE AKTIENGESELLSCHAFT
2006-08-31	MA	Patent expired