FI110693B - Menetelmä Aspergillus-kantojen rakentamiseksi geenikorvauksen avulla - Google Patents

Menetelmä Aspergillus-kantojen rakentamiseksi geenikorvauksen avulla Download PDF

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Publication number
FI110693B
FI110693B FI893818A FI893818A FI110693B FI 110693 B FI110693 B FI 110693B FI 893818 A FI893818 A FI 893818A FI 893818 A FI893818 A FI 893818A FI 110693 B FI110693 B FI 110693B
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FI
Finland
Prior art keywords
gene
chymosin
expression
fungal host
region
Prior art date
Application number
FI893818A
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English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI893818L (fi
FI893818A0 (fi
Inventor
Hartingsveldt Wim Van
Den Hondel Cees A M J J Van
Annemarie E Veenstra
Den Berg Johannes A Van
Original Assignee
Dsm Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8199839&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=FI110693(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Dsm Nv filed Critical Dsm Nv
Publication of FI893818A0 publication Critical patent/FI893818A0/fi
Publication of FI893818L publication Critical patent/FI893818L/fi
Application granted granted Critical
Publication of FI110693B publication Critical patent/FI110693B/fi

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/87Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/90Stable introduction of foreign DNA into chromosome
    • C12N15/902Stable introduction of foreign DNA into chromosome using homologous recombination
    • C12N15/905Stable introduction of foreign DNA into chromosome using homologous recombination in yeast

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Distillation Of Fermentation Liquor, Processing Of Alcohols, Vinegar And Beer (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Orthopedics, Nursing, And Contraception (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
FI893818A 1988-08-16 1989-08-14 Menetelmä Aspergillus-kantojen rakentamiseksi geenikorvauksen avulla FI110693B (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP88201743 1988-08-16
EP88201743 1988-08-16

Publications (3)

Publication Number Publication Date
FI893818A0 FI893818A0 (fi) 1989-08-14
FI893818L FI893818L (fi) 1990-02-17
FI110693B true FI110693B (fi) 2003-03-14

Family

ID=8199839

Family Applications (1)

Application Number Title Priority Date Filing Date
FI893818A FI110693B (fi) 1988-08-16 1989-08-14 Menetelmä Aspergillus-kantojen rakentamiseksi geenikorvauksen avulla

Country Status (14)

Country Link
EP (1) EP0357127B1 (da)
JP (1) JP2752714B2 (da)
KR (1) KR900003366A (da)
AT (1) ATE181111T1 (da)
AU (1) AU636572B2 (da)
CA (1) CA1341226C (da)
DE (1) DE68929013T2 (da)
DK (1) DK175196B1 (da)
ES (1) ES2134754T3 (da)
FI (1) FI110693B (da)
GR (1) GR3030901T3 (da)
HU (1) HUT51336A (da)
IL (1) IL91309A (da)
PT (1) PT91453B (da)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69032616T2 (de) * 1989-06-16 1999-03-11 Genencor International, Inc., Rochester, N.Y. Dna-sequenzen, vektoren und fusionspolypeptide zur erhöhung der sekretion gewünschter polypeptide von filamentösen fungi
NL9001388A (nl) 1990-06-19 1992-01-16 Unilever Nv Recombinant dna, cel die daarvan afgeleid dna bevat, enzym waarvoor het recombinant dna codeert en toepassingen daarvan.
PT98419B (pt) * 1990-07-24 1999-01-29 Gist Brocades Nv Processo para a preparacao de sequencias de adn que codificam para xilanases, de construcoes de adn que contem essas sequencias, paraa transformacao de hospedeiros microbianos com essas construcoes, para a preparacao de xilanases por expressao nesses hospedeiros e para a degradacao de xilano por accao dessas xilanases
AU664223B2 (en) * 1991-12-09 1995-11-09 Unilever Plc Process for producing/secreting a protein by a transformed mould using expression/secretion regulating regions derived from an (aspergillus) endoxylanase II gene
AU4383293A (en) * 1992-05-19 1993-12-13 Tsi Corporation Production of transgenics by joining regulatory and coding regions in vivo
WO1995017513A1 (en) * 1993-12-23 1995-06-29 Novo Nordisk A/S Retransformation of filamentous fungi
BE1009488A4 (fr) * 1994-06-17 1997-04-01 Solvay Systeme d'expression, vecteur d'integration et cellule transformee par ce vecteur d'integration.
BE1008737A3 (fr) * 1994-01-28 1996-07-02 Solvay Systeme d'expression, vecteur d'integration et cellule transformee par ce vecteur d'integration.
BE1008267A3 (fr) * 1994-01-28 1996-03-05 Solvay Systeme d'expression, vecteur d'integration et cellule transformee par ce vecteur d'integration.
JP5303084B2 (ja) 1997-04-11 2013-10-02 コニンクリーケ デーエスエム ナムローゼ フェンノートシャップ 工業的組み換え生物を溝築するための手段としての遺伝子変換
TW409035B (en) 1997-06-04 2000-10-21 Gist Brocades Bv Starch-based enzyme granulates
EP3351637B1 (en) 2004-04-02 2020-06-10 DSM IP Assets B.V. Filamentous fungal mutants with improved homologous recombination efficiency
EP1776461A2 (en) 2004-04-16 2007-04-25 DSMIP Assets B.V. Fungal promoters for expressing a gene in a fungal cell
CA2583460A1 (en) 2004-10-15 2006-04-20 Dsm Ip Assets B.V. Homologous amds genes as selectable marker
US7888489B2 (en) 2005-01-24 2011-02-15 Dsm Ip Assets B.V. Method for producing a compound of interest in a filamentous fungal cell
CA2630445C (en) 2005-11-28 2016-11-15 Dsm Ip Assets B.V. Enzyme preparations yielding a clean taste
EP1954812B1 (en) 2005-11-29 2012-11-21 DSM IP Assets B.V. Dna binding site of a transcriptional activator useful in gene expression
WO2007063133A2 (en) 2005-12-01 2007-06-07 Dsm Ip Assets B.V. Genes useful for the industrial production of citric acid
EP2511372A1 (en) 2006-11-02 2012-10-17 DSM IP Assets B.V. Improved production of secreted proteins by filamentous fungi
EA018840B1 (ru) 2007-02-15 2013-11-29 ДСМ АйПи АССЕТС Б.В. Рекомбинантная клетка-хозяин для получения соединения, представляющего интерес
JP5497632B2 (ja) 2007-05-09 2014-05-21 ノボザイムス アクティーゼルスカブ 関心対象のポリペプチドを産生するライブラリークローンの選択に適した発現クローニング法
EP2421986A1 (en) 2009-04-22 2012-02-29 DSM IP Assets B.V. Process for the production of a recombinant polypeptide of interest
EA201201125A1 (ru) 2010-02-11 2013-03-29 ДСМ АйПи АССЕТС Б.В. Клетка-хозяин, способная продуцировать ферменты, пригодные для деградации лигноцеллюлозного материала
AU2011273351A1 (en) 2010-07-01 2013-01-17 Dsm Ip Assets B.V. A method for the production of a compound of interest
US20150197760A1 (en) 2012-06-19 2015-07-16 Dsm Ip Assets B.V. Promoters for expressing a gene in a cell
WO2014003555A1 (en) 2012-06-27 2014-01-03 Rijksuniversiteit Groningen Improved penicillin production
JP6468561B2 (ja) 2012-07-19 2019-02-13 ディーエスエム アイピー アセッツ ビー.ブイ.Dsm Ip Assets B.V. AgsE欠損株
WO2014142647A1 (en) 2013-03-14 2014-09-18 Wageningen Universiteit Fungals strains with improved citric acid and itaconic acid production
DK3077517T3 (da) 2013-12-02 2019-02-11 Dsm Ip Assets Bv Isstrukturerende protein
EP3915384A1 (en) 2014-11-07 2021-12-01 DuPont Nutrition Biosciences ApS Recombinant host cell expressing beta-galactosidase and/or transgalactosylating activity deficient in cellulase
WO2016110512A1 (en) 2015-01-06 2016-07-14 Dsm Ip Assets B.V. A crispr-cas system for a yeast host cell
WO2016110453A1 (en) 2015-01-06 2016-07-14 Dsm Ip Assets B.V. A crispr-cas system for a filamentous fungal host cell
US10590436B2 (en) 2015-01-06 2020-03-17 Dsm Ip Assets B.V. CRISPR-CAS system for a lipolytic yeast host cell
WO2016193292A1 (en) 2015-06-02 2016-12-08 Dsm Ip Assets B.V. Use of ice structuring protein afp19 expressed in filamentous fungal strains for preparing food
US20200063166A1 (en) 2017-03-13 2020-02-27 Dsm Ip Assets B.V. Zinc binuclear cluster transcriptional regulator-deficient strain

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK122686D0 (da) * 1986-03-17 1986-03-17 Novo Industri As Fremstilling af proteiner
GB8610600D0 (en) * 1986-04-30 1986-06-04 Novo Industri As Transformation of trichoderma
FI872102L (fi) * 1986-06-06 1987-12-07 Panlabs Inc Expressionssystem hos filamentala fungi.
US4693536A (en) * 1986-06-12 1987-09-15 Molex Incorporated Insulation displacement terminal
WO1989001969A1 (en) * 1987-09-04 1989-03-09 Novo-Nordisk A/S Process for the production of protein products in aspergillus and promoters for use in aspergillus

Also Published As

Publication number Publication date
PT91453B (pt) 1995-05-31
DE68929013T2 (de) 1999-10-21
JP2752714B2 (ja) 1998-05-18
ES2134754T3 (es) 1999-10-16
KR900003366A (ko) 1990-03-26
IL91309A0 (en) 1990-03-19
GR3030901T3 (en) 1999-11-30
IL91309A (en) 1997-11-20
FI893818L (fi) 1990-02-17
AU4002189A (en) 1990-02-22
PT91453A (pt) 1990-03-08
CA1341226C (en) 2001-05-01
DK399889A (da) 1990-02-17
JPH02174673A (ja) 1990-07-06
FI893818A0 (fi) 1989-08-14
HUT51336A (en) 1990-04-28
DK175196B1 (da) 2004-07-05
AU636572B2 (en) 1993-05-06
DK399889D0 (da) 1989-08-15
DE68929013D1 (de) 1999-07-15
EP0357127B1 (en) 1999-06-09
ATE181111T1 (de) 1999-06-15
EP0357127A1 (en) 1990-03-07

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