FI64349C - Foerfarande foer framstaellning av ett terapeutiskt anvaendbart l-pyroglutamyl-l-histidyl-glysin och dess salter - Google Patents

Foerfarande foer framstaellning av ett terapeutiskt anvaendbart l-pyroglutamyl-l-histidyl-glysin och dess salter Download PDF

Info

Publication number: FI64349C
Authority: FI; Finland
Prior art keywords: formula; compound; pyroglutamyl; group; histidyl
Prior art date: 1977-09-06

Application number

FI782714A

Other languages

English (en)

Finnish (fi)

Other versions

FI782714A7 (fi

FI64349B (fi

Inventor

Karl-Ludwig Reichelt

Olav Edvardt Trygstad

Original Assignee

Nyegaard & Co As

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1977-09-06

Filing date

1978-09-05

Publication date

1983-11-10

1978-09-05 Application filed by Nyegaard & Co As filed Critical Nyegaard & Co As

1979-03-07 Publication of FI782714A7 publication Critical patent/FI782714A7/fi

1983-07-29 Application granted granted Critical

1983-07-29 Publication of FI64349B publication Critical patent/FI64349B/fi

1983-11-10 Publication of FI64349C publication Critical patent/FI64349C/fi

Links

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229920001223 polyethylene glycol Polymers 0.000 description 1
229940093430 polyethylene glycol 1500 Drugs 0.000 description 1
229940113125 polyethylene glycol 3000 Drugs 0.000 description 1
229920000656 polylysine Polymers 0.000 description 1
108010026466 polyproline Proteins 0.000 description 1
229920002689 polyvinyl acetate Polymers 0.000 description 1
239000011118 polyvinyl acetate Substances 0.000 description 1
229920000036 polyvinylpyrrolidone Polymers 0.000 description 1
239000001267 polyvinylpyrrolidone Substances 0.000 description 1
235000013855 polyvinylpyrrolidone Nutrition 0.000 description 1
239000000843 powder Substances 0.000 description 1
108090000623 proteins and genes Proteins 0.000 description 1
102000004169 proteins and genes Human genes 0.000 description 1
238000000746 purification Methods 0.000 description 1
230000006340 racemization Effects 0.000 description 1
239000011541 reaction mixture Substances 0.000 description 1
239000011347 resin Substances 0.000 description 1
229920005989 resin Polymers 0.000 description 1
CVHZOJJKTDOEJC-UHFFFAOYSA-N saccharin Chemical compound C1=CC=C2C(=O)NS(=O)(=O)C2=C1 CVHZOJJKTDOEJC-UHFFFAOYSA-N 0.000 description 1
229940081974 saccharin Drugs 0.000 description 1
235000019204 saccharin Nutrition 0.000 description 1
239000000901 saccharin and its Na,K and Ca salt Substances 0.000 description 1
239000004208 shellac Substances 0.000 description 1
ZLGIYFNHBLSMPS-ATJNOEHPSA-N shellac Chemical compound OCCCCCC(O)C(O)CCCCCCCC(O)=O.C1C23[C@H](C(O)=O)CCC2[C@](C)(CO)[C@@H]1C(C(O)=O)=C[C@@H]3O ZLGIYFNHBLSMPS-ATJNOEHPSA-N 0.000 description 1
229940113147 shellac Drugs 0.000 description 1
235000013874 shellac Nutrition 0.000 description 1
239000000741 silica gel Substances 0.000 description 1
229910002027 silica gel Inorganic materials 0.000 description 1
235000019812 sodium carboxymethyl cellulose Nutrition 0.000 description 1
229920001027 sodium carboxymethylcellulose Polymers 0.000 description 1
238000010532 solid phase synthesis reaction Methods 0.000 description 1
239000000600 sorbitol Substances 0.000 description 1
238000004611 spectroscopical analysis Methods 0.000 description 1
235000013599 spices Nutrition 0.000 description 1
239000003381 stabilizer Substances 0.000 description 1
239000008107 starch Substances 0.000 description 1
235000019698 starch Nutrition 0.000 description 1
238000010254 subcutaneous injection Methods 0.000 description 1
239000007929 subcutaneous injection Substances 0.000 description 1
239000000126 substance Substances 0.000 description 1
239000000375 suspending agent Substances 0.000 description 1
238000013268 sustained release Methods 0.000 description 1
239000003765 sweetening agent Substances 0.000 description 1
235000020357 syrup Nutrition 0.000 description 1
239000006188 syrup Substances 0.000 description 1
238000010998 test method Methods 0.000 description 1
239000002562 thickening agent Substances 0.000 description 1
239000004408 titanium dioxide Substances 0.000 description 1
235000010215 titanium dioxide Nutrition 0.000 description 1
QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 description 1
MWOOGOJBHIARFG-UHFFFAOYSA-N vanillin Chemical compound COC1=CC(C=O)=CC=C1O MWOOGOJBHIARFG-UHFFFAOYSA-N 0.000 description 1
FGQOOHJZONJGDT-UHFFFAOYSA-N vanillin Natural products COC1=CC(O)=CC(C=O)=C1 FGQOOHJZONJGDT-UHFFFAOYSA-N 0.000 description 1
235000012141 vanillin Nutrition 0.000 description 1
239000000080 wetting agent Substances 0.000 description 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0821—Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp
- C07K5/0825—Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp and Glp-amino acid; Derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Obesity (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Diabetes (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Hematology (AREA)
Child & Adolescent Psychology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)

FI782714A 1977-09-06 1978-09-05 Foerfarande foer framstaellning av ett terapeutiskt anvaendbart l-pyroglutamyl-l-histidyl-glysin och dess salter FI64349C (fi)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GB3719377		1977-09-06
GB3719377		1977-09-06

Publications (3)

Publication Number	Publication Date
FI782714A7 FI782714A7 (fi)	1979-03-07
FI64349B FI64349B (fi)	1983-07-29
FI64349C true FI64349C (fi)	1983-11-10

Family

ID=10394541

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FI782714A FI64349C (fi)	1977-09-06	1978-09-05	Foerfarande foer framstaellning av ett terapeutiskt anvaendbart l-pyroglutamyl-l-histidyl-glysin och dess salter

Country Status (12)

Country	Link
EP (1)	EP0001174B1 (de)
JP (1)	JPS5951935B2 (de)
AT (1)	AT363624B (de)
AU (1)	AU518157B2 (de)
CA (1)	CA1105926A (de)
DE (1)	DE2860944D1 (de)
DK (1)	DK390678A (de)
ES (1)	ES473090A1 (de)
FI (1)	FI64349C (de)
IT (1)	IT1106283B (de)
NO (1)	NO147601C (de)
ZA (1)	ZA785022B (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4328134A (en) *	1980-05-06	1982-05-04	Schally Andrew Victor	Anorexigenic peptides
JPS59188235U (ja) *	1983-06-01	1984-12-13	東レ株式会社	建築用下見板
US4719207A (en) *	1984-06-25	1988-01-12	Yamanouchi Pharmaceutical Co., Ltd.	CNS active substituted azetidinone compounds
US4785003A (en) *	1984-10-16	1988-11-15	Biomeasure, Inc.	N-disubstituted glycine and B-amino-propionic acid derivatives having anti-ulcer activity
US4598067A (en) *	1984-10-16	1986-07-01	Biomeasure, Inc.	Antiulcer compounds
JPH03502685A (ja) *	1987-09-17	1991-06-20	ハフスルンド　ニイコメッド　バイオレグ　アクチーセルスカペット	医薬組成物の製造のためのトリペプチドの使用および医薬組成物と方法

1978
- 1978-09-05 CA CA310,610A patent/CA1105926A/en not_active Expired
- 1978-09-05 JP JP53109040A patent/JPS5951935B2/ja not_active Expired
- 1978-09-05 DE DE7878300346T patent/DE2860944D1/de not_active Expired
- 1978-09-05 AU AU39554/78A patent/AU518157B2/en not_active Expired
- 1978-09-05 NO NO783027A patent/NO147601C/no unknown
- 1978-09-05 DK DK390678A patent/DK390678A/da not_active Application Discontinuation
- 1978-09-05 IT IT50967/78A patent/IT1106283B/it active
- 1978-09-05 ES ES473090A patent/ES473090A1/es not_active Expired
- 1978-09-05 AT AT0642878A patent/AT363624B/de not_active IP Right Cessation
- 1978-09-05 ZA ZA00785022A patent/ZA785022B/xx unknown
- 1978-09-05 EP EP78300346A patent/EP0001174B1/de not_active Expired
- 1978-09-05 FI FI782714A patent/FI64349C/fi not_active IP Right Cessation

Also Published As

Publication number	Publication date
CA1105926A (en)	1981-07-28
DE2860944D1 (en)	1981-11-12
ZA785022B (en)	1979-10-31
ES473090A1 (es)	1979-10-16
NO147601C (no)	1983-05-11
ATA642878A (de)	1981-01-15
AU518157B2 (en)	1981-09-17
DK390678A (da)	1979-03-07
EP0001174A1 (de)	1979-03-21
FI782714A7 (fi)	1979-03-07
AU3955478A (en)	1980-03-13
AT363624B (de)	1981-08-25
FI64349B (fi)	1983-07-29
IT1106283B (it)	1985-11-11
EP0001174B1 (de)	1981-08-12
JPS5488267A (en)	1979-07-13
IT7850967A0 (it)	1978-09-05
NO783027L (no)	1979-03-07
JPS5951935B2 (ja)	1984-12-17
NO147601B (no)	1983-01-31

Legal Events

Date	Code	Title	Description
2004-08-31	MM	Patent lapsed	Owner name: REICHELT, KARL LUDVIG

Publication	Publication Date	Title
IE60128B1 (en)	1994-06-01	Hydroxylamine derivatives,their preparation and use as medicaments
EP0184309A2 (de)	1986-06-11	Peptide welche Aminosäureester 11 bis 23 von VIP besitzen
EP0253190B1 (de)	1992-12-30	Teilweise retro-invertierte Analoge des Tuftsin, Methode zu ihrer Herstellung und pharmazeutische Zusammensetzungen, die sie enthalten
US4386073A (en)	1983-05-31	Tripeptides acting on the central nervous system and a process for the preparation thereof
US4487765A (en)	1984-12-11	Peptides
JPH01157998A (ja)	1989-06-21	Ｌ−プロリン誘導体及びその製造方法並びにそれを含有する医薬組生物
IE841782L (en)	1985-01-12	Peptides
EP0000252B1 (de)	1982-02-03	Peptiden, Verfahren zu dessen Herstellung und denen enthaltende pharmazeutische Präparate
FI64349B (fi)	1983-07-29	Foerfarande foer framstaellning av ett terapeutiskt anvaendbart l-pyroglutamyl-l-histidyl-glycin och dess salter
HU182866B (en)	1984-03-28	Process for preparing new tetrapeptide derivatives
US5811548A (en)	1998-09-22	Tri-and tetracyclic compounds
US4260601A (en)	1981-04-07	Chemical compounds
US4322436A (en)	1982-03-30	Novel substituted phenylacetic acid amide compounds
US4250192A (en)	1981-02-10	Novel substituted phenylacetic acid amide compounds
US4420490A (en)	1983-12-13	Substituted phenylacetic acid amide compounds
GB2130590A (en)	1984-06-06	Peptides
SE461042B (sv)	1989-12-18	Peptider med tillvaextbefraemjande aktivitet jaemte veterinaera kompositioner innehaallande naemnda peptider
CZ293445B6 (cs)	2004-04-14	Způsob přípravy derivátu pentapeptidu, meziprodukt pro tuto přípravu a použití tohoto derivátu
WO1988005049A1 (en)	1988-07-14	Novel compounds
EP0156063A2 (de)	1985-10-02	Hypoglycemische Tetrapeptide
EP0001335B1 (de)	1981-07-08	Ein Peptid, Verfahren zu seiner Herstellung und dieses Peptid enthaltende Zusammensetzungen
CA1064942A (en)	1979-10-23	Pyroglutamy compounds having antidepressive activity and process for their manufacture
HU181402B (en)	1983-07-28	Process for preparing new peptides with psychopharmacological activity
HU220875B1 (en)	2002-06-29	Pentapeptide derivative, production thereof and their intermediates
US4271152A (en)	1981-06-02	Psycho-pharmacological peptides